1030results about "Cation exchanger materials" patented technology

A method including pretreating ground lithium-containing ceramics to form alkali coated ceramics, leaching the alkali coated ceramics to form a leachate comprising a filtrate and a solid residue, preferentially extracting lithium from the filtrate to form a lithium rich solution and a raffinate, precipitating a crude lithium carbonate from the lithium rich solution and purifying the crude lithium carbonate to produce a battery grade lithium carbonate. A method including leaching a slurry comprising lithium-containing ceramics, water, a strong base, and an alkaline earth metal oxide / hydroxide at a pressure ranging from 0 to 1450 psi and at a temperature ranging from 100 to 500°C to form a leached slurry comprising a liquid filtrate and a solid residue, processing the liquid filtrate to recover a lithium-rich organic solution, and processing the lithium-rich organic solution to produce a battery-grade lithium compound and sodium sulfate.

Described herein are methods of recovering lithium from dilute lithium sources. The methods include extracting lithium from an extraction feed using direct lithium extraction in an extraction stage to yield a lithium intermediate, performing one or more concentration operations, each concentration operation concentrating an input stream to yield an output feed, wherein the input stream is obtained from the lithium intermediate and / or the extraction feed is obtained from the output feed. At least one of the concentration operations includes a membrane separation operation having a plurality of reactors in series each having a semi-permeable membrane, such as a counter-flow reverse osmosis operation. Methods may also include generating a low TDS stream as a permeate from any of the one or more concentration operations, wherein the low TDS stream is recycled or used as fresh water.

The present disclosure relates to the extraction of lithium from liquid resources such as natural and synthetic brines, leachate solutions from clays and minerals, and recycled products. Herein are systems and processes for extracting lithium using ion exchange materials, where transition metal impurities may be removed from the synthetic lithium solution. In some embodiments, the transition metal species are reformulated to form ion exchange materials to be used in the systems and processes described herein.

The invention relates to a strong cation exchange chromatographic filler as well as a preparation method and application thereof. The strong cation exchange chromatographic filler comprises sulfonated poly (glycidyl methacrylate)-divinyl benzene microspheres. The strong cation exchange chromatographic filler provided by the invention can simultaneously show excellent separation selectivity on rare earth elements, and also has long-term stability and excellent cycle performance, so that the economic cost is reduced, and the strong cation exchange chromatographic filler has relatively high economic benefits and is green and environment-friendly.

A method is provided, comprising: obtaining, for a chromatography machine including a first dispersed plug flow reactor (DPFR) and a continuous stirred tank reactor (CSTR) prior to a column, and a second DPFR after the column, geometric measurements associated with the second DPFR; generating, by a processor, transport model parameters for a transport model associated with the second DPFR based on the geometric measurements; feeding a tracer molecule into the chromatography machine; capturing one or more tracer molecule measurements based on the tracer molecule traveling through the chromatography machine; and estimating, by the processor, based on the transport model associated with the second DPFR and the one or more tracer molecule measurements based on the tracer molecule traveling through the chromatography machine, one or more transport model parameters for a transport model associated with the first DPFR and the CSTR.

The present invention relates to the process to prepare recombinant lectin having amino acid sequence of SEQ ID NO:1, wherein the process comprises fed-batch fermentation of a clone in a host cell at specific feeding rate with carbon to Nitrogen ratio of 3:1 to 6:1. The invention also relates to the process of purification of recombinant lectin having amino acid sequence of SEQ ID NO: 1.

The invention relates to the technical field of pharmaceutical separation, and discloses a device, method and application of ursodeoxycholic acid preparation and purification. The device comprises a separation tank, wherein a batching center cylinder is rotatably installed inside the separation tank, and a plurality of elution tubes are arranged around the batching center cylinder. The batching center cylinder rotates forward, and centrifugal force is used to load adsorption resin into each elution tube. Then, the batching center cylinder rotates reversely, and the volume of each elution tube is poured out by anti-centrifugal force, so as to achieve a more convenient effect of replacing the adsorption resin. The replaced adsorption resin is cleaned outside the device and reused. The purification method and application thereof realize column loading, sample loading and elution in the separation tank in sequence without stopping the machine for operation, and simplify the column loading and column replacement operations, so as to solve the problem that the separation and purification process in the prior art is complicated and not suitable for batch production, so as to meet the industrial production requirements of solvent recycling.

The present invention relates to a system for capturing carbon dioxide from an air stream. The system includes a carbon dioxide capturing unit that includes a humidity / temperature adjusting unit with an evaporative cooling unit and a CO2 adsorbing unit. The CO2 adsorbing unit includes a sorbent column made of polyamine-Cu (II) complex resin. The humidity / temperature adjusting unit receives air stream from ambient atmosphere and process the air stream to obtain a humidity-adjusted air stream. The CO2 adsorbing unit receives the humidity-adjusted air stream to pass through the sorbent column. The sorbent column selectively adsorbs the CO2 from the humidity-adjusted air stream. The sorbent column is regenerated using an alkaline stream to separate the adsorbed CO2 from the sorbent column.

The invention belongs to the technical field of radioactive isotope separation and purification, and particularly relates to a device for separating and purifying carrier-free lutetium 177. Comprising a mounting rack, a salt transfer assembly arranged in the middle of the front side of the mounting rack, a valve assembly arranged in the middle of the rear side of the mounting rack, a separation and purification column arranged on one side of the salt transfer assembly, a sample injection system arranged on one side of the valve assembly, a fraction assembly arranged above the mounting rack and a waste liquid assembly arranged on one side of the mounting rack, the control terminal is used for controlling the sampling system and the on-off of valves in the valve assembly so as to control the flowing of liquid in the separation and purification device, so that the functions of ytterbium and lutetium separation, lutetium-to-salt concentration and ytterbium-to-salt recovery in the separation and purification device are realized. The problems that in the prior art, an overall device for separating and purifying carrier-free lutetium-177 is large in size and occupied area, the requirement for the automation control degree is high, and the service life of parts is short are solved.

Disclosed herein are methods and systems for the use of extraction chromatography resins to concentrate Ac from dilute solutions that may contain Th isotopes and / or other isotopes, such as Ra. As disclosed herein, at least some extraction chromatography resins strongly retain trivalent actinides between 4 and 6 M HNO3 that can be recovered in good yields with small volumes of dilute acids. These small volumes of acid eluents result in significant concentration of the solution of the trivalent / certain tetravalent ions, such that they can be further processed without requiring lengthy evaporation steps that are utilized in standard Ac concentration methods.

Provided is a cation exchange membrane in which when a hydroxide aqueous solution showing strong alkalinity is produced by using an electrodialyzer, significant swelling in the cation exchange membrane in contact with the hydroxide aqueous solution is suppressed, destruction of a cation exchange resin due to polyvalent cations contained as impurities in a raw material inorganic salt is suppressed, and the capacity of the cation exchange membrane is hardly lowered.　This cation exchange membrane is characterized by having an electric resistance of 2.0-5.0 (Ω∙cm2), as measured at 25ºC in 0.5 mol / L of a NaCl aqueous solution, and a dimensional change rate of at most 1.2%.

A bipolar membrane in which a cation-exchange membrane and an anion-exchange membrane are joined to each other, wherein a leakage ratio of gluconic acid at 60° C. is not more than 1.0%, and the cation-exchange membrane is supported by a polyolefin reinforcing member and, further, contains a polyvinyl chloride.

The invention discloses a method for extracting a target product from a milk raw material, and relates to the technical field of food processing. According to the method, before strong anion exchange chromatography is carried out, a synergistic pretreatment step of ultrafiltration and conductivity adjustment is introduced, so that acceleration, synergism, quality improvement and cost reduction of the chromatography process are realized, and the technical bottlenecks of low speed, easiness in pollution, instability and the like of the traditional ion exchange chromatography during treatment of milk raw materials are overcome; and a solution is provided for high-efficiency, high-purity and large-scale production of the beta-lactoglobulin and the alpha-lactalbumin. According to the method, strong anion exchange chromatography and weak anion exchange chromatography can be combined, so that the extraction purity of beta-lactoglobulin and alpha-lactalbumin can be further improved; in addition, the method can synchronously realize high-efficiency extraction of various target substances such as casein micelles, lactose and milk mineral salts, so that the additional value and resource utilization efficiency of milk source byproducts are greatly improved.

The invention discloses a parameter differential separation process, and relates to the technical field of separation. The defects in the prior art are overcome. The method specifically comprises the following steps: carrying out a generalized separation process by using a parameter differential moving bed, and operating the generalized separation process to eliminate a displacement zone in chromatographic sequential operation; the method comprises the following steps: contacting a mobile-phase liquid feeding solution with solid-phase resin / adsorbent filler through a novel mass transfer equilibrium contact method, and starting to obtain a characteristic separation curve; the multiple components contained in the mobile phase liquid feed solution are separated by a new mass transfer equilibrium contact process such that at least one component contained in the mobile phase liquid feed solution can be adsorbed onto the resin / adsorbent. The method realizes final separation of a large-scale production separation system, improves the maximum mass transfer efficiency, can also be used for a binary separation system in the separation process of glucose and fructose, reduces the consumption of washing liquid, and reduces the final power consumption.

The present invention provides a kit and a detection method for synchronously detecting catecholamines and their metabolites, which relates to the technical field of analytical detection. The kit contains a diluent, a solid-phase extraction reagent, an LC-MS / MS detection reagent, a solid-phase extraction device, and a solid-phase extraction packing material. Among them, the solid-phase extraction packing material creatively adopts zwitterionic exchange microspheres containing both carboxyl and quaternary ammonium groups. The kit can not only synchronously and efficiently separate and detect 8 kinds of catecholamines and their metabolites in urine samples, but also separate and detect 6 kinds of amino-containing catecholamines and their metabolites in blood samples. When the above kit is used to separate and detect catecholamines and their metabolites, the extraction recovery rate is relatively high, and the linear range covers the reference value range of normal detection, which can significantly shorten the detection time of urine samples, improve the detection efficiency of mass spectrometry, and is conducive to popularization and application in clinical detection.

The present disclosure provides various characteristics for treating tail brine extracted from a bromine plant, when said brine contains residual bromine and chlorine with low pH and high ORP values that will be used in a lithium extraction production facility. The method conditions the extracted tail brine by adding either sodium hydroxide or ammonium hydroxide to bring its pH levels to between 5.5 and 6.5. The conditioned tail brine then gets pre-treated with hydrazine in either less than 70 ppm if used in combination with sodium hydroxide; or 195 ppm if used with ammonium hydroxide until the ORP levels have reached to below 100 mV. The extracted tail brine is then processed through DLE processing device having four groups of adsorption columns filled with lithium adsorption resins that, after treating the extracted tail brine, discharges the raw eluate solution to an effluent tail brine tank using an effluent tail brine pump connected to the DLE processing device.

A full solid-waste micro-expansive concrete and its preparation method are provided, and relate to the field of concrete material technologies. The full solid-waste micro-expansive concrete includes the following components in parts by weight: 920-1060 parts of a coarse aggregate, 460-582 parts of a fine aggregate, 11-19 parts of an expansive agent, 389-512 parts of a modified solid-waste-based cementitious material, and 231-268 parts of water. The coarse aggregate is coal gangue. The fine aggregate is waste ceramic. The modified solid-waste-based cementitious material includes a solid-waste-based clinker, modified polyvinyl alcohol, and a modified anion exchange resin. The solid-waste-based clinker is prepared from the coal gangue, carbide slag, and desulfurization gypsum. The expansive agent is obtained by calcining the carbide slag. The concrete prepared can ensure the initial strength of the concrete, and guarantee continuous micro-expansion in the later stage, compensating for shrinkage and thereby increasing the overall strength of the concrete.

The preparation method comprises the following steps: by taking a seed ball matrix as a base ball, preparing monodisperse porous polymer microspheres through one-step swelling polymerization, then converting residual double bonds on the surfaces of the polymer microspheres into epoxy groups by adopting an oxidation reaction, then grafting a dextran hydrophilic layer to completely cover hydrophobic sites on the surfaces, and then carrying out chemical modification and ligand bonding by utilizing hydroxyl on dextran, so as to obtain the polymer microspheres. The prepared ion exchange polymer filler is porous, high in hydrophilicity and high in exchange capacity and is successfully applied to protein separation and purification. Therefore, the ion exchange purification filler prepared by the method has a good application prospect.

The present invention discloses an acid-sugar separation resin and a preparation method thereof, belonging to separation resin technology. The resin is formed by modifying sodium styrene sulfonate and a chloride ion type strong alkaline anion exchange resin, and then heating and polymerizing with an azo compound water-soluble free radical initiator. The acid-sugar separation resin provided by the present invention is an amphoteric ion exchange resin, and the functional groups contained in the resin structure: quaternary ammonium salt groups, so that the resin obtains excellent acid-sugar separation effect and improves the acid-sugar separation rate; the sulfonate groups contained can avoid the sulfuric acid tailing phenomenon, avoid the sulfuric acid tailing phenomenon to reduce the concentration of recovered sulfuric acid, thereby increasing the cost of subsequent sulfuric acid concentration.

The invention discloses composite resin for removing metal ions as well as a preparation method and application of the composite resin, and belongs to the technical field of resin materials. In order to solve the problem that the traditional cation exchange resin has poor removal rate on heavy metals in a solution containing alkali metals and heavy metals at the same time, the invention provides the composite resin with a weak acid cation functional group and a nitrogen-containing chelating functional group at the same time. The composite resin contains a nitrogen-oxygen-containing chelating functional group and a weakly acidic cation functional group, the nitrogen-oxygen-containing chelating functional group can selectively remove heavy metal ions such as chromium, and the weakly acidic cation functional group can effectively remove alkali metal ions such as calcium. Therefore, the composite resin has the advantages of cation exchange resin and chelating resin, heavy metal ions and alkali metal ions in an ethanolamine stock solution can be effectively removed, and the concentration of the metal ions in the ethanolamine solution treated by the composite resin is lower than 30 ppb.

The present invention relates to a process for separating rubidium ions from saline solutions rich in other monovalent ions, particularly sodium and potassium. The process relies on rubidium ions adsorption via ion exchange performed by metal-hexacy anoferrate particles. The process of the present invention provides pure rubidium salt with estimated production costs that do not exceed 20% of the current price.

Systems and methods for generating radionuclides, such as radium-224. Systems herein may include a first cartridge having a first opening, a second opening, and a chamber therebetween having a first resin having affinity for thorium-228 and bismuth-212; a second cartridge having a first opening, a second opening, and a chamber therebetween having a second resin having affinity for thorium-228 and bismuth-212, a third cartridge having a first opening, a second opening, and a chamber therebetween comprising a third resin having affinity for thorium-228 and bismuth-212, a fourth cartridge having a first opening, a second opening, and a chamber therebetween having a third resin having affinity for lead-212; wherein a continuous flow path is formed from a top of the first cartridge though the second cartridge, through the third cartridge, and to a bottom of the fourth cartridge during system use.

The invention discloses a method for preparing radiation-resistant polystyrene resin and controlling the aperture of the radiation-resistant polystyrene resin. The preparation method of the radiation-resistant polystyrene resin comprises the following steps: fully dissolving polyvinyl alcohol in deionized water, adding an organic phase containing styrene and the like into the deionized water, uniformly stirring and mixing, heating and carrying out a synthetic reaction to prepare non-porous matrix microspheres, and carrying out pore-forming and surface modification treatment on the matrix microspheres. Compared with the prior art, rapid preparation of the radiation-resistant porous mass transfer resin is achieved through two steps, the high grafting rate is kept through accurate control over a cross-linked skeleton, meanwhile, radiation resistance is considered, and the method has the advantages that the process is simple, the cost is low, the particle size is controllable and narrow in distribution, relevant parameters are easy to standardize, and the method is suitable for industrial amplification.

This invention relates to a device comprising polyethylene sulfone (PES) and additional suitable polymers with high load of Prussian blue analogue nanoparticles for removal of monovalent or divalent cation contaminants, optionally doped, and process for the preparation and methods for use thereof. The device and method relate to selectively and effectively remove ammoniacal nitrogen removal and recovery as a valuable resource, and removing radioactive cesium and / or other monovalent or divalent cations from contaminated water.

The invention relates to the technical field of biomacromolecule separation and purification engineering, and discloses a chromatographic separation method for removing endotoxin in a vaccine preparation, which comprises the following steps: preparing an equilibrium buffer solution containing citrate with specific concentration and L-arginine hydrochloride; providing a mixed mode chromatography medium with hydrophobic and ion exchange complex ligands and balancing with a buffer; according to the method, through the synergistic effect of 8.0-12.0 mmol / L of citrate and 150-250 mmol / L of L-arginine hydrochloride, the endotoxin micelle structure is destroyed and is induced to be dissociated into monomers, and meanwhile, L-arginine is used for inhibiting monomer aggregation, so that the monomers are diffused into inner holes of the medium in a small size to be adsorbed, and the endotoxin micelle structure is separated into the medium. Therefore, the problem of separation caused by size overlapping of endotoxin micelles and antigens is solved, and double breakthrough of deep removal of endotoxin and high recovery rate of antigens is realized.

A problem to be solved by the present invention is to provide an ion exchange membrane that can increase the surface area of a membrane effective for ion permeation, properly decreases the electric resistance of a flow passage between membranes and the attachment of a contaminating substance thereto, also enhances the mechanical strength of the membrane itself, and further, is less deformed or damaged due to swelling over a wide range of salt concentrations and even if there is a large difference in salt concentration between two solutions contacted with the membrane. The present invention provides an ion exchange membrane having a concavo-convex shape, wherein the ion exchange membrane has a flat portion in the vicinity of ends, and a convex curve and a concave curve resulting from curvatures of the ion exchange membrane itself form a convex part and a concave parts, respectively, in the concavo-convex shape of the ion exchange membrane, wherein the convex part extends linearly or curvedly, the concave part between the convex parts is flat, the concave part includes a first concave part adjacent to the convex part in the lateral direction of the convex part, along the longitudinal direction of the convex part, the convex part has an apex and a side face in the longitudinal direction, and the side face is inclined from the apex toward the first concave part.

The invention provides a production process of SEMI-G5-grade high-purity NMP (N-Methyl Pyrrolidone), which is characterized in that metal ions, magnetic foreign / non-magnetic foreign particulate matters and the like of conventional industrial-grade NMP are completely removed by adopting a multi-section rectification, resin adsorption and precise filtration process, so that the SEMI-G5-grade NMP reaches the SEMI-G5 grade in an ultra-clean high-purity reagent; and the use requirements on the ultra-clean high-purity NMP in the fields of semiconductors, integrated circuits and novel display are met.

The invention discloses a strongly acidic cation exchange chromatography material and a preparation method thereof. The chromatography material takes microspheres as a matrix material, and takes halogenated alkyl sodium benzenesulfonate and hydroxyl-containing halogenated alkyl sodium sulfonate as functional groups. The preparation method comprises the following steps: epoxy activation: dispersing microspheres in a continuous phase, adding a reducing agent, an alkaline solution and a grafting reagent, and reacting to obtain epoxy activated microspheres; preliminary sulfonation: enabling the epoxy activated microspheres to react with hydroxyl-containing halogenated alkyl sodium sulfonate serving as a first sulfonating agent under an alkaline condition to obtain preliminarily sulfonated microspheres; deep sulfonation: enabling the preliminarily sulfonated microspheres to react with halogenated sodium alkyl benzene sulfonate serving as a second sulfonating agent to obtain a target product. The strongly acidic cation exchange chromatography material provided by the invention can achieve the effects of high protein adsorption capacity and high ion exchange site density.

The invention provides a kit for synchronously detecting catecholamine and metabolites thereof and a detection method, and relates to the technical field of analysis and detection. The kit comprises a diluent, a solid-phase extraction reagent, an LC-MS / MS detection reagent, a solid-phase extraction device and a solid-phase extraction filler. Wherein the solid-phase extraction filler creatively adopts an amphiphilic ion exchange microsphere containing two functional groups, namely carboxyl and quaternary ammonium at the same time. The kit can be used for synchronously and efficiently separating and detecting eight catecholamines and metabolites thereof in a urine sample; and 6 kinds of catecholamines containing amino groups and metabolites thereof in a blood sample can be separated and detected. When the kit is used for separating and detecting catecholamine and metabolites thereof, the extraction and recovery rate is high, the linear range covers the reference value range of normal detection, the detection time of a urine sample can be remarkably shortened, the detection efficiency of mass spectrum is improved, and popularization and application in clinical detection are facilitated.

The invention provides a continuous fluid separation system for recovering lithium from mirabilite, and relates to the technical field of continuous fluid separation. A continuous fluid separation system for recovering lithium from mirabilite comprises a plurality of treatment subsystems, each treatment subsystem comprises an exchange area, a material washing area and an acid regeneration analysis area which are arranged in sequence, and each separation unit of the treatment subsystems is filled with a titanium adsorbent filler; the exchange area adopts a three-parallel two-serial feeding mode; gradient washing is carried out in a three-string mode in the material washing area; and the acid regeneration analysis area adopts a three-parallel analysis mode. According to the continuous fluid separation system for recovering lithium from mirabilite, the recovery rate of lithium can exceed 90%, continuous operation is achieved, product components and concentration are kept stable, and the use amount of washing water and an acid regenerant is greatly reduced.