344 results about "Dialysis fluid" patented technology

The invention relates to the technical field of medical equipment, and discloses an intelligent temperature control and flow control system for hemodialysis, which comprises a dialysis pipeline shunting shell; the two main pipelines are arranged in the dialysis pipeline shunting shell, and a plurality of slave pipelines are arranged between the two main pipelines; when the flow rate of the liquid is low, the slave pipeline is far away from the heating component, the temperature of the liquid cannot rise too fast under the condition that the flow rate is low, the knob part can move to the slave pipeline when controlling the valve component to increase the flow rate of the liquid, and the slave pipeline moves close to the heating component. The distance between the auxiliary pipeline and the temperature rising component is reduced, when the flow rate of liquid with large flow is high, the auxiliary pipeline gets close to the temperature rising component, heat generated by the temperature rising component can be better received by the auxiliary pipeline and conducted to the liquid, and the flow adjusting system and the temperature control system can cooperate to achieve the purpose that the flow adjusting system and the temperature control system work together. A preset temperature value can be provided for the dialysis liquid all the time when the flow is increased or decreased.

The present invention discloses a hemodialysis fluid balance control method, device, electronic device, and medium, relating to the technical field of intelligent regulation. The hemodialysis fluid balance control method includes: in response to a patient experiencing a hypotensive event, determining whether the hypotensive event is caused by a hypoglycemic event; if the hypotensive event is caused by a hypoglycemic event, switching the patient's dialysate from a sugar-free dialysate to a sugar-containing dialysate; monitoring the patient's real-time blood glucose concentration; and controlling the dialysate flow rate during the patient's dialysis based on the real-time blood glucose concentration. The embodiments of the present application achieve the goal of reducing interference with hemodialysis while ensuring compensation for hypoglycemia.

The invention discloses a dialysate supply device for hemodialysis, which comprises a tank body, a partition plate, a material storage tank, a liquid storage box, a stirring rod and a power mechanism, and is provided with a feeding mechanism, a liquid discharge mechanism and a supply device, the feeding mechanism performs lifting reciprocating motion through a first conical block and a second conical block which are driven by a cam; quantitative closed feeding of dialysis dry powder is achieved, the problem that a traditional blade cuts a dry powder bag to cause scrap pollution is solved, a liquid discharging mechanism adopts a double-column-shaped shell to be matched with a piston plate and a one-way valve and is in linkage with a feeding mechanism, medicine liquid is synchronously and quantitatively extracted, and a supply device utilizes a floating block to ascend and descend along with the liquid level, and a sealing block is driven to be opened and closed through an adjusting rod. According to the automatic feeding device for the dialysis dry powder, the dialysis dry powder is accurately metered, mixed and fed, and the preparation quality of the dialysis liquid and the clinical use safety are improved.

This disclosure relates to systems for medical fluid pumps and related methods. In some implementations, a system includes a system for draining fluid from a peritoneal cavity of a patient comprising a microfluidic pump; a drain bag fluidly coupled to the microfluidic pump; and an inlet line coupled to the drain bag, wherein the microfluidic pump is configured to apply a negative pressure to an interior of the drain bag to draw effluent from a peritoneal cavity of the patient along the inlet line and into the drain bag. In some implementations, a system for performing peritoneal dialysis includes a microfluidic pump; a dual chamber bag fluidly coupled to the microfluidic pump, where the dual chamber bag includes an effluent chamber configured to be fluidly coupled to a peritoneal cavity of a patient; a dialysate chamber; and a flexible membrane separating the effluent chamber from the dialysate chamber.

The invention discloses a peritoneal dialysis system which comprises an abdominal cavity pipeline with the first end communicated with the abdominal cavity of a human body; the semi-permeable membrane assembly comprises a membrane, a first side and a second side, the first side and the second side are separated by the membrane, and the first side is communicated with the second end of the abdominal cavity pipeline so as to receive the abdominal cavity dialysate from the abdominal cavity pipeline and inject the abdominal cavity dialysate into the abdominal cavity of the human body; the external liquid path system comprises an external liquid pipeline communicated with the second side, and the external liquid pipeline comprises a waste liquid outlet for outputting dialysis waste liquid led out from the peritoneal dialysis liquid through the membrane; when the peritoneal dialysis solution is led out, the membrane allows moisture and small molecular solutes in the peritoneal dialysis solution to permeate into the second side and entraps a macromolecular penetrant on the first side so as to maintain the osmotic pressure of the peritoneal dialysis solution.

The disclosure relates to systems and methods for increasing the functional capabilities of a sorbent-based dialysis system. The systems and methods allow for the mode of operation of the dialysis system to be switched between single pass mode and a sorbent based multi-pass mode by controlling an amount of water added to the dialysate between 0% to 100% of the dialysate flow rate.

This utility model relates to the field of packaging and sealing technology, and discloses a peritoneal dialysis fluid packaging and sealing machine, including a support plate. A slide rail is fixedly connected to the upper surface of the support plate, and a slider is fixedly connected to the upper surface of the slide rail. A clamping assembly is provided outside the slider, the clamping assembly including a clamping plate. The clamping plate is disposed outside the slider, and a connecting rod two is fixedly connected to the outer wall of the clamping plate. A fixing post one is rotatably connected to one end of the outer wall of the connecting rod two, and a fixing post two is rotatably connected to one end of the connecting rod two. A connecting rod three is rotatably connected to the outer wall of the fixing post one. In this utility model, the clamping plate stably clamps the packaging bag by driving the gears and connecting rods through a motor. Combined with the sliding of the slider on the slide rail, the packaging bag can be accurately transported to the sealing position, improving the stability of clamping and transporting, ensuring accurate positioning of the packaging bag during the sealing process, reducing sealing deviations caused by displacement, and improving sealing quality.

This invention discloses an open, non-contact liquid heating method, comprising: collecting temperature data of multiple points of dialysis fluid and heating unit, and obtaining flow rate deviation and temperature sensor consistency deviation indices during dialysis fluid infusion; preprocessing the temperature data to obtain a stable multi-source temperature data sequence; fusing the multi-source temperature data to obtain the dialysis fluid characterization temperature, and analyzing it in conjunction with temperature change characteristics, flow rate deviation, and temperature sensor consistency deviation indices to construct a system state characterization quantity; identifying the heating stage based on the system state characterization quantity, using the dialysis fluid characterization temperature as the control target, generating heating control quantities according to the heating stage, and introducing compensation corrections when the flow rate changes; performing anomaly detection based on the system state characterization quantity, and jointly judging it in conjunction with the flow rate deviation and temperature sensor consistency deviation indices, generating anomaly scores based on the judgment results, and outputting corresponding hierarchical control strategies.

The present application relates to an extracorporeal blood treatment system (50) for treating a subject, the system comprising: an extracorporeal blood circuit (52); a dialysate fluid circuit (54); the extracorporeal blood circuit and the dialysate fluid circuit being separated by a membrane (56) of a filtration unit (58); at least one blood pump (60) for controlling the flow of blood through the blood circuit; at least one dialysate fluid pump (62) for controlling the flow of dialysate fluid through the dialysate fluid circuit (54); a system computing unit (64) operatively connected to the blood pump and to the dialysate fluid pump, the system computing unit having at least one input; wherein the system computing unit is adapted to receive a desired blood concentration of glutamine GLN b , to receive a desired blood concentration of glucose GLUCOSE b , and to receive a desired blood concentration of ketone bodies KETONE b ; the system computing unit being adapted to control the blood pump and the dialysate fluid pump such that an actual concentration value of glutamine GLN a is driven to approach GLN b , and an actual concentration value of glucose GLUCOSE a is driven to approach D b , and an actual concentration value of ketone bodies is driven to approach KETONE a . The present application relates to a treatment device for use in an extracorporeal blood treatment system, a method for treating cancer using the system, a controller for controlling the method and a dialysis liquid suitable for use in the method.

The utility model relates to the technical field of peritoneal dialysis equipment, and discloses a pipeline speed controller which comprises a lower clamping plate and an upper clamping plate, a peritoneal dialysis pipeline body is arranged between the lower clamping plate and the upper clamping plate in a clamped mode, and a plurality of clamping mechanisms are arranged on the two sides of the lower clamping plate and the two sides of the upper clamping plate in a clamped mode. A pipeline flow speed control mechanism is fixedly arranged on the upper end face of the upper clamping plate, and first handles are arranged on the two sides of the lower clamping plate correspondingly. According to the peritoneal dialysis catheter, the catheter flow speed control mechanism is arranged at the upper end of the upper clamping plate, the baffle can compress the peritoneal dialysis catheter body by rotating the rotating handle, and therefore the purpose of controlling the flow speed of dialysate in the peritoneal dialysis catheter body is achieved, and meanwhile the upper clamping plate and the lower clamping plate are clamped and positioned through the limiting rod and the limiting hole; the upper clamping plate and the lower clamping plate can be detached by detaching the clamping mechanism after dialysis is completed, so that the pipeline speed controller can be repeatedly used, and the dialysis cost is reduced.

A proportioning system includes a solute container filled with dry solutes, a source of water, a container of electrolyte concentrate, a fluid circuit connecting the solute container to the source of water and the container of electrolyte concentrate, the fluid circuit having an empty mixing container, a controller configured to transfer water from the source of water to the solute container through the fluid circuit so as to prepare a solute concentrate solution in the solute container. The controller is configured to transfer fluid from the container of electrolyte concentrate to a mixing container as well as a solute concentrate from the solute container to the mixing container and further adding water to said mixing container to form a medicament therein.

The utility model discloses a hemodialysis filtration treatment device, which relates to the technical field of hemodialysis filtration and comprises a base, a rotating wheel is fixedly mounted at the bottom of the base, a dialysate box is fixedly mounted on the upper surface of the base, a dialysis machine main body is fixedly mounted on the upper surface of the base, and a dialysis pump is rotatably mounted on one side of the dialysis machine main body. A control screen is fixedly installed at the top of the dialysis machine body, a liquid outlet pipe is fixedly installed on the dialysis machine body, a supporting rod is fixedly installed on the upper surface of the base, a liquid storage box is arranged on the upper surface of the base, a handle is fixedly installed on the liquid storage box, and a filtering mechanism is arranged at the other end of the supporting rod. Through the structural arrangement of the filtering mechanism and the fixing and adjusting mechanism, filtering holes in the filtering box can be prevented from being blocked, meanwhile, metabolic waste and waste liquid can be treated respectively, the treatment efficiency is improved, the dialyzer can be fixed, the height of the dialyzer can be adjusted, and the dialyzer can be prevented from falling off and can be adjusted to the height suitable for the dialyzer.

The present application relates to the technical field of automatic peritoneal dialysis machine, and particularly relates to a peritoneal dialysis fluid constant-temperature supply and flow self-adaptive regulation and control system; comprising: a liquid supply driving module, a non-contact end heating module, a multi-dimensional signal sensing module and a temperature-pressure coupling multi-state collaborative control module; the present application introduces a non-contact electromagnetic resonance end heating structure and a temperature-pressure coupling multi-state collaborative control algorithm, on the one hand, uses air gap and high-frequency electromagnetic eddy current to realize safe endogenous heat of dialysis fluid in the pipeline, effectively avoids the risk of local thermal deformation and plasticizer precipitation of the pipeline caused by traditional contact heating, improves the biological safety of fluid infusion, constructs a feedforward defense mechanism based on the change rate of end temperature, and through extraction of the dynamic amplitude and static component of the hydraulic waveform, realizes accurate identification of cold stimulation spasm, regular physiological disturbance and pipeline mechanical obstruction, and after diagnosing mechanical obstruction, actively drives the stepping motor to perform reverse backflushing action.

The utility model relates to the field of medical treatment, in particular to a quantifiable dialysate filling device. The dialysate filling device capable of quantifying can seal the filling pipe when the filling pipe is folded, and waste caused by dialysate leakage is avoided. A quantifiable dialysate filling device comprises a base, a liquid storage barrel, a metering pump and the like, the upper side of the left portion of the base is connected with the liquid storage barrel, and the right side of the upper portion of the liquid storage barrel is connected with the metering pump. The sliding plate moves upwards under the action of threads, the first roller rotates and moves upwards along the first guide frame, the extrusion frame is driven to move rightwards, the extrusion frame moves rightwards to extrude the sealing frame, the sealing frame is driven to move downwards to be closed, and the lower portion of a canning pipe is blocked. And the effects that the canning pipe can be blocked when the canning pipe is folded, and waste caused by dialysate leakage is avoided are achieved.

Extracorporeal blood treatment device comprising a hydraulic system (B) with several lines (7, 9) for supplying dialysate for dialysis treatment and a control system (15) comprising at least one electrical component (17A, 17B, 17C), wherein the hydraulic system (B) has at least one port (11) for the inflow of a fluid into the extracorporeal blood treatment device, and the extracorporeal blood treatment device has a cooling device (19) for cooling the at least one electrical component (17A, 17B, 17C) of the control system (15), which has at least one liquid-coolable cooling element (21) which is in thermal contact with the at least one electrical component (17A, 17B, 17C) of the control system (15), wherein the cooling device (19) has at least one inlet (22A) which is in fluid communication with the port (11) for the inflow of a fluid.and has at least one outlet (22B) which is in fluid communication with a drain (10, 31), and wherein the cooling element is designed such that the liquid flows through the cooling element (21) and the thermal contact between the at least one electrical component (17A, 17B, 17C) of the control system (15) and the cooling element (21) is a contact contact, characterized in that the permeate supplied centrally to the device for extracorporeal blood treatment is used as the cooling liquid for the cooling element (21).

To provide a personal dialysis machine that allows for visual confirmation of the remaining amount of concentrated dialysis solution with a simple configuration, while suppressing cost increases. [Solution] The personal dialysis machine 100 includes drug solution tanks 95, 96 and drug solution solenoid valves 81, 82 for storing drug solution for cleaning the piping 5, and concentrate tanks 93, 94 and concentrate solenoid valves 83, 84 for storing concentrate for dialysis fluid, and includes a drug solution concentrate usage determination unit 51 that determines the amount of at least one of the drug solution and concentrate that has been drawn up by the pump 86, a drug solution concentrate remaining amount calculation unit 52 that calculates the remaining amount of drug solution concentrate based on the amount determined by the drug solution concentrate usage determination unit 51, a drug solution concentrate remaining amount determination unit 55 that determines whether the remaining amount of drug solution concentrate is less than a predetermined standard amount, and a display unit 60 that displays a fact if the remaining amount of drug solution concentrate is less than a predetermined standard amount.

The embodiment of the utility model provides a concentrated liquid supply pipeline purging device which comprises a liquid storage tank, a liquid supply pipeline, a first liquid discharge pipeline, a first liquid discharge valve and a blowing assembly, and the liquid storage tank is used for storing dialysate; the liquid supply pipeline is connected with the liquid storage tank, and the liquid supply pipeline is provided with a liquid supply port for supplying liquid to the hemodialysis device; the first liquid discharge pipeline is connected with the liquid supply pipeline; the first liquid discharge valve is arranged on the first liquid discharge pipeline; and the air blowing assembly is connected with the liquid supply pipeline. After the hemodialysis device finishes treatment of a patient on the same day, the air blowing assembly can be used for blowing liquid in the liquid supply pipeline to be dry, so that the interior of the liquid supply pipeline is kept dry, and bacteria are not prone to breeding. The dialysate in the liquid storage tank can be conveyed to the liquid supply pipeline before the patient is treated on the next day, compared with the prior art, the time consumed for replacing the dialysate in the liquid supply pipeline is short, pure water and the dialysate consumed for replacing the dialysate overnight are saved, and efficient replacement of the dialysate in the supply pipeline is facilitated.

This invention discloses an adaptive adjustment method for dialysis solution mixing parameters based on MPSO (Particle Swarm Optimization), relating to the field of dialysate preparation technology. The method includes: initializing a digital twin model and a causal inference network; constructing a virtual mapping of the physical structure of the solution mixing device and calibrating parameters to form a calibrated virtual-real mapping decision support environment; preprocessing multi-dimensional process data from historical solution mixing batches based on the virtual-real mapping decision support environment; updating the causal inference network using a causal discovery algorithm; learning the causal relationship between dialysis solution mixing parameters and solution quality; and establishing a dynamically updated causal relationship network. Based on the dynamically updated causal relationship network, iteratively searching for the optimal solution of the fitness function through particle swarm optimization generates a pre-optimized parameter set for the virtual environment. This invention, through an MPSO-based particle swarm optimization mechanism in a dynamic virtual environment, enables adaptive searching and recalibration of key parameters such as pump power, turbulence angle, and mixing time under multiple operating conditions.

The invention discloses an intelligent hemodialysis system based on a sodium clearance ratio (RNA) and a control method of the intelligent hemodialysis system. The system integrates five layers of functions to form a complete closed loop: (1) a sensing layer: based on a dialysate conductivity difference value, applying a corrected Gibbs-Donnan formula (Ceq = [Na] d / sigma, sigma = 0.97) and Kalman filtering to reversely deduce plasma sodium concentration in real time; (2) a calculation layer is used for calculating RNa = Naactual / Narget in real time, and RNa = Naactual / Narget; (3) a monitoring layer, namely an RNa + Kt / V double-index instrument panel + three-level alarm; (4) a [Na] d regulation and control curve, RNa closed-loop regulation and three safety rules are calculated through a control layer-double-chamber model; and (5) a feedback layer, cross-course trend analysis and automatic model optimization. The system is compatible with dialysis machines of various brands and can be integrated as an additional module.

The utility model discloses a kind of dialysis tubes of bidirectional laminar flow, including pipe body, inner passage, outer passage and fiber bundle film;Two liquid inlets and two liquid outlets are provided on the side of pipe body;Inner passage is communicated with two liquid inlets;Outer passage is set around inner passage, outer passage lower end is communicated to inner passage lower end, and outer passage is communicated to two liquid outlets;Fiber bundle film is communicated to the two ports of pipe body to transport back blood.The utility model is communicated to inner passage bottom by setting inner passage and outer passage in pipe body, and when dialysate is injected into inner passage through liquid inlet, dialysate can form dialysate laminar flow in inner passage, dialysate can form waste liquid laminar flow in outer passage after flowing into outer passage by dialysis, to form bidirectional laminar flow to improve hemodialysis effect.

The present application relates to the field of medical devices, and discloses a peritoneal dialysis patient peritonitis early warning device based on microfluidic technology, comprising a peritoneal dialysis external catheter and a microfluidic detection module; the peritoneal dialysis external catheter comprises a main passage for dialysis liquid infusion or dialysis waste liquid drainage, and a detection branch selectively communicated with the main passage; a flow path switching structure is arranged on the peritoneal dialysis external catheter, and the flow path switching structure is used for switching between a normal state and a detection state. In the present application, the detection branch selectively communicated with the main passage is arranged on the peritoneal dialysis external catheter, and the flow path switching structure is used for switching between the normal state and the detection state, so that the dialysis waste liquid can enter the microfluidic detection module for detection while maintaining the drainage of the main passage, in-situ detection is realized without changing the basic operation process of peritoneal dialysis, and good clinical process compatibility is achieved.

The invention belongs to the technical field of medical equipment, and particularly discloses a clinical hemodialysis device and a using method thereof.The clinical hemodialysis device comprises a dialysis box, and a dialysis assembly is arranged on one side of the dialysis box; the dialysis assembly comprises a dialyzer, a liquid inlet pipe, a liquid outlet pipe, a dialysate inlet, a dialysate outlet, a dialysis membrane, an inner partition plate and an adjusting structure. By means of the flow guiding structure, flow guiding can be conducted when blood enters the dialysis cavity, the situation that blood easily flows in a deviated mode after entering the dialysis cavity, so that no blood passes through the surface of a dialysis membrane on one side, the blood and dialysis efficiency is affected is prevented, the treatment duration is shortened, complications are reduced, and the treatment effect is improved by heating the blood. Therefore, the blood is kept at the temperature acceptable by the human body, the comfort of a patient during treatment is improved, and the dialysis treatment is safely and efficiently carried out.

The present disclosure is directed to methods for scrubbing low levels of urea from aqueous solutions such as a dialysate from dialysis, and including blood and blood products, and devices capable of employing these methods.

1. Name of the product in this design: Sealing cap (dialysis fluid container). 2. Purpose of this design: For use as a sealing cap for dialysis fluid containers. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application discloses a hemodialysis machine dialysate potassium ion real-time automatic regulation system and belongs to the technical field of medical equipment, which solves the problem of how to accurately regulate the potassium ion concentration in the dialysate of a hemodialysis machine. The man-machine interface of the host computer mainly comprises blood potassium concentration display, regulation system function selection and lower computer function setting functions. The lower computer controller mainly completes the cooperative control of the clamping valve and the peristaltic pump, realizes the function control of the electrode, and, combined with the real-time optimal regulation strategy solved by the nonlinear MPC control algorithm, realizes the switching selection of dialysate with different potassium ion concentrations by electromagnetic valve driving control. The ion selective electrode is adopted to realize the real-time sampling detection of the potassium ion concentration in blood, and the control of the peristaltic pump and the rotary clamping valve is combined to realize the calibration, cleaning and activation of the electrode. The application realizes the real-time switching of dialysate with different potassium ion concentrations and completes the accurate regulation of dialysate with different potassium ion concentrations in the dialysis process.

Described herein are systems and methods for performing peritoneal dialysis. According to one aspect, the disclosure provides a sterile interface connection for connecting a water purification system to a disposable source of dialysate concentrates. The sterile interface connection can include a chamber comprising an inlet adapted to be connected to the water purification system on a proximal end and a valve on a distal end. The sterile interface connection can also include spring-loaded needle disposed in the chamber. The spring-loaded needle can move between a retracted configuration in which the spring-loaded needle is fully retracted into the chamber and the valve is closed and sealed, and an extended configuration in which the spring-loaded needle extends through the valve into the disposable source of dialysate concentrates.

The utility model relates to the technical field of medical instruments, in particular to a bag for peritoneal dialysis fluid, which comprises a storage unit, an infusion unit and a control unit. The short pipe is provided with grooves and protrusions, the protrusions are integrally arranged on the upper side and the lower side of the short pipe respectively, and the grooves are formed in the left side and the right side of the short pipe respectively; the diversion unit comprises a first diversion tube and a second diversion tube, the first diversion tube is fixedly connected with the dialysis bag, and one end of the second diversion tube is fixedly connected with a short tube; the fastening and sealing unit comprises a fastening part and a sealing part, the fastening part is arranged at one end of the second flow guide pipe, the short pipe is arranged in the fastening part, and the sealing part is rotationally connected with the fastening part. Therefore, the short pipe is protected from being influenced by a humid environment or moisture, and the risk of infection is reduced.

A fluid path system and method are provided for disrupting, shedding, removing, and preventing the accumulation of biofilms in a dialysate path of an extracorporeal blood treatment device. The dialysate path may include a dialyzer discharge line, a discharge line, a dialyzer supply line, and a bypass system. At least one ultrasound device may be positioned and configured to generate ultrasound waves in the dialysate path and to propagate the ultrasound waves along at least a portion of the dialysate path. The ultrasound can be used to disrupt a biofilm. An ionizing electrode pair may also be implemented, or alternatively, to disrupt, shed, remove, and prevent the accumulation of biofilm. The system and method can be implemented in particular in a non-disposable part of a fluid path system of an extracorporeal blood treatment device and are useful.

The invention relates to a medical treatment device (1) comprising a stationary unit (1a) and a mobile unit (1b) that can be separated from the stationary unit (1a). The invention relates to a stationary unit (1a), which can be connected, for example, to a stationary or domestic water source (5) and / or can be connected, for example, to a stationary or domestic water outlet (13) by means of a discharge line (11) in order to discharge dialysis waste liquid, and which comprises a mixing device (19), which in turn is configured to prepare and / or heat dialysis liquid for treating a patient (P). The mobile unit (1b) is configured to treat the patient (P), in particular renal replacement treatment, where the mobile unit (1b) comprises at least one line selected from the group consisting of a dialysis fluid input line (31) to the patient, a dialysis waste fluid output line (32) from the patient, and a patient connection line (33) for connection to the patient, and / or comprising a connector for connecting the line to the mobile unit (1b). The stationary unit (1a) and the mobile unit (1b) each comprise a connection (27, 29) so as to be connectable in fluid communication with each other.