26 results about "Dialysate flow" patented technology

The disclosure relates to systems and methods for increasing the functional capabilities of a sorbent-based dialysis system. The systems and methods allow for the mode of operation of the dialysis system to be switched between single pass mode and a sorbent based multi-pass mode by controlling an amount of water added to the dialysate between 0% to 100% of the dialysate flow rate.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a strain measuring device which includes a load cell and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.

The application discloses a kind of roll type diffusion dialysis membrane module and preparation method thereof, including cylinder, U-shaped tube;U-shaped tube straight pipe part upper end is connected respectively with the inlet and outlet pipe of diffusion liquid and dialysate;Wherein, between a pair of diagonal straight pipe parts, ion exchange membrane is equipped, and both sides of ion exchange membrane are equipped with a flow channel screen, above the pair of diagonal straight pipe parts, by ion exchange membrane and flow channel screen, spiral is wound into cylinder by mutual close, and the end of ion exchange membrane and flow channel screen winding is fixed on another pair of straight pipe parts respectively;Space supported by flow channel screen constitutes fluid channel and is always located at both sides of ion exchange membrane, one side constitutes diffusion liquid flow channel and is connected with a pair of diffusion liquid inlet and outlet connector communication, the other side constitutes dialysate flow channel and is connected with a pair of dialysate inlet and outlet connector communication, the application solves the problem that liquid inlet and outlet are difficult to set when multiple membrane modules are commonly processed in higher integrated degree and mass transfer efficiency is lower.

To provide a method for adjusting the dialysate flow rate and a hemodialysis apparatus that can quickly adjust the dialysate flow rate to a desired flow rate. [Solution] The method for adjusting the dialysate flow rate 100 includes: a pump control value determination step in which a pump control value corresponding to a desired dialysate flow rate is determined based on a calibration value that shows the correlation between a desired dialysate flow rate and the pump control value of the circulation pump 92; a pump operation step in which the circulation pump is operated with the pump control value determined in the pump control value determination step; a difference calculation step in which the difference between the current dialysate flow rate and the desired dialysate flow rate is calculated; and a calibration value correction step in which the calibration value is corrected based on the difference calculated in the difference calculation step.

A method includes receiving, by a processor of a dialysis machine, a dialysate flow rate, a bicarbonate setting value, a signal from a pressure sensor configured to measure a pressure within a container, and a signal indicating a state of a fill valve; determining, based on the signal received from the pressure sensor and the state of the fill valve, fill parameters; determining a volume of the container based on at least two of the fill parameters; determining a depletion time in which the concentrate will be depleted from the container based on the volume of the container, the dialysate flow rate, and the bicarbonate setting value; determining, based on the depletion time, an amount of time remaining before the concentrate will be depleted from the container; and causing the dialysis machine to indicate the amount of time remaining before the concentrate will be depleted from the container.

The utility model relates to a directional feeding device for a dialyzer end cover, a dialysate flow opening of the end cover is of a circumferential protruding structure, the directional feeding device comprises a straight vibration feeding assembly, a static material channel assembly, an end cover transferring mechanism and an end cover directional mechanism, the static material channel assembly is arranged in the conveying direction of the straight vibration feeding assembly, and the end cover directional mechanism is arranged on the end cover transferring mechanism. The end cover transferring mechanism clamps and moves the end cover, and a stop block and a deflector rod in the end cover orientation mechanism are matched to limit the rotation angle of the dialysate flow opening, so that the dialysate flow opening is forcibly corrected to the preset direction. The end cover feeding device solves the problem that in the prior art, when end covers are fed, the directions of dialysate flow openings of the end covers are inconsistent. The device can greatly improve the production efficiency and reduce the time and cost of manual adjustment.

The present invention aims to provide a dialysis apparatus with optimized placement and operability of the monitor unit. Furthermore, the present invention aims to provide a dialysis apparatus that reduces the burden on technicians in attaching blood circuits. [Solution] The dialysis apparatus comprises a housing 1 consisting of an electrical unit and a dialysate unit, a blood circuit connected to the patient through which blood and dialysate flow, an extracorporeal circulation unit 8 located on the front of the housing 1 and connected to the blood circuit, a dialyzer 2 located on the side of the housing, and a monitor unit 3 for operating each function and understanding the treatment status. Furthermore, the monitoring unit 3 is characterized by being positioned on the upper surface of the extracorporeal circulation unit as a deployable lid.

A renal failure blood therapy system includes a memory device storing a therapy target for a patient. The system also includes a processor configured to receive the therapy target for the patient, receive a desired solute concentration for the patient, and apply the therapy target and the desired solute concentration as inputs to an optimization routine. The processor is also configured to execute the optimization routine to determine at least one dialysis therapy prescription specifying at least a dialysis therapy duration, a dialysis therapy frequency, and at least one of a dialysis therapy blood flow rate or a dialysis therapy dialysate flow rate. The processor is further configured to display the at least one dialysis therapy prescription for confirmation or selection by a clinician and transmit the selected or confirmed dialysis therapy prescription to a dialysis machine for a subsequent dialysis treatment for the patient.

The application discloses a peritoneal dialysis catheter assembly capable of preventing fibrin clot blockage, which comprises a drainage tube and a cleaning rod. The drainage tube is internally provided with an axially extending drainage cavity, and the drainage tube comprises an insertion section and a guide section, and the insertion section is provided with a plurality of drainage holes; the cleaning rod is arranged in the drainage cavity, the cleaning rod is coaxially arranged with the drainage tube, and the cleaning rod is provided with a plurality of blades. By means of the energy of the dialysate flow, the blades guide the local deflection and acceleration of the flow direction, induce continuous turbulence and vortex near the inner wall of the drainage cavity, the shear force in the turbulence area can effectively strip the fibrin clot adhered to the cavity wall, and the stirring action of the vortex prevents the deposition of new clots on the surface of the cavity wall. The arrangement of the plurality of blades can generate vortexes with alternating directions at different axial positions, avoid the single stable mode of the flow field and reduce the scouring efficiency, so that the unobstructed state of the drainage cavity can be maintained for a long time without relying on external power.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

A blood purification apparatus is provided which returns blood in a blood circuit to a body. The blood purification apparatus includes a blood circuit and a dialysate circuit connected via a blood purifier; an air introduction path connected to the dialysate circuit; an air introduction portion provided to the dialysate circuit or the air introduction path and introducing air into the dialysate circuit via the air introduction path to bring the dialysate circuit to a positive pressure; and a control device which controls the air introduction portion in a manner that dialysate flows from the dialysate circuit to the blood circuit, and controls the blood circuit and the dialysate circuit in a manner that blood in the blood circuit and the blood purifier is returned to the body by causing the dialysate to flow from the dialysate circuit to the blood circuit.

Provided are a method for adjusting a dialysate flow rate and a hemodialyzer capable of quickly completing adjustment of the dialysate flow rate to a desired flow rate. A method for adjusting a dialysate flow rate (100) includes: a pump control value determination step of determining a pump control value corresponding to a desired dialysate flow rate, on the basis of a calibration value indicating a correlation between the desired dialysate flow rate and a pump control value of a circulation pump (92); a pump operation step of operating the circulation pump with the pump control value determined in the pump control value determination step; a difference calculation step of obtaining a difference between a current dialysate flow rate and the desired dialysate flow rate; and a calibration value correction step of correcting the calibration value on the basis of the difference calculated in the difference calculation step.

Provided is a blood purification device that returns blood in a blood circuit to the body. The blood purification device comprises a blood circuit and a dialysate circuit which are connected through a blood purifier; an air introduction path connected to the dialysate circuit; an air introduction unit that is provided in the dialysate circuit or the air introduction path, introduces air into the dialysate circuit via the air introduction path, and causes the dialysate circuit to be at a positive pressure; and a control device that controls the air introduction unit so that the dialysate flows from the dialysate circuit to the blood circuit, and that controls the blood circuit and the dialysate circuit so that the blood in the blood circuit and the blood purifier returns to the body by causing the dialysate to flow from the dialysate circuit to the blood circuit.

This application relates to a blood pressure pattern recognition and intervention system for hemodialysis in end-stage renal disease. The method includes: a dialysis device for performing hemodialysis on a user; a data collection device; a memory and a processor, the processor loading a dialysis control program to execute the following steps: filtering and combining data collected by the data collection device and a historical database to obtain blood pressure-related features; generating classification factors and grouping patients into different groups; establishing training and testing sets, training a machine learning model to obtain a blood pressure prediction model, and validating and adjusting the model based on the testing set; inputting the data collected by the data collection device into the blood pressure prediction model, and obtaining dialysis device control parameters based on the blood pressure prediction model; and controlling the dialysate temperature, dialysate flow rate, and dialysis duration of the dialysis device based on the dialysis device control parameters. This application has the advantage of being able to calculate and adjust the parameters of the dialysis device according to the user's real-time condition.

This invention discloses an integrated dialysate parameter measurement device relating to the field of blood purification technology, comprising: a dual-loop processing architecture arranged along a fluid channel, including an independent main control loop and a protection loop; the main control loop includes a first sensing module arranged along the dialysate flow direction; the protection loop includes a second sensing module arranged along the dialysate flow direction; both the first and second sensing modules are configured to measure the temperature and conductivity of the flowing dialysate; an electrical signal isolation element is disposed between the first and second sensing modules and connected to a reference potential to form electrical signal isolation during conductivity measurement by the two sets of conductivity measuring electrodes; wherein, the dual-loop processing architecture is configured to process data based on data collected by the first and / or second sensing modules. Using this device can improve the accuracy and stability of dialysate parameter measurement and enhance the safety and reliability of system operation.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient, to the dialyzer, and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. The hemodialysis system includes a hemodialysis machine and dialysate generator which are physically connectable to, and disconnectable from, one another. To connect the hemodialysis machine and dialysate generator together, both the hemodialysis machine and dialysate generator possess connectable and disconnectable electrical connectors and fluid connectors which are positioned and constructed to allow both a fluid and electrical connection between the two machines. The hemodialysis machine includes a processor and a user interface, preferably in the form of a touchscreen, that is capable of controlling both the functions of the hemodialysis machine and the dialysate generator.

A dialysis system includes a dialysis device, a flow path through which a dialysate supplied to the dialysis device or a liquid component for adjusting the dialysate flows, and a cleaning liquid supply portion for supplying a cleaning liquid to the flow path. The cleaning liquid supply portion has an acid supply portion for supplying an acidic cleaning liquid (a) to the flow path, and an alkali supply portion for supplying a cleaning liquid (b) containing sodium hypochlorite to the flow path. A cleaning method of the dialysis system includes a first cleaning process in which the inside of the dialysis device is cleaned with a cleaning liquid (a+b) obtained by mixing the cleaning liquid supplied from the acid supply portion and the cleaning liquid (b) supplied from the alkali supply portion.

This invention relates to the field of blood purification control technology, and discloses a CRRT fluid management decision-making system and method based on hemodynamic monitoring, comprising: a blood flow acquisition module for acquiring systolic blood pressure, mean arterial pressure, and heart rate to form a current hemodynamic dataset and determine a baseline dataset; a grading determination module for determining the hemodynamic grade based on the current hemodynamic dataset and the baseline dataset; a dehydration boundary module for determining the hard boundary of the net dehydration rate; a dehydration command module for generating and trimming net dehydration commands; a pump control linkage module for writing net dehydration commands and linkage adjustment of replacement fluid flow rate and dialysate flow rate; a safety control module for entering or de-entering a safety mode and updating the net dehydration command; and a termination and takeover module for outputting a stop control command or a manual takeover flag. This invention achieves automatic decision-making and orderly execution of net dehydration operations under safe conditions during continuous blood purification.

To provide various systems and methods for performing hemodialysis more efficiently, easily and / or at a lower cost.SOLUTION: A hemodialysis system (6000) comprises a dialysis unit (6001) and a user interface unit (6002) for displaying safety-critical information about a dialysis process. The hemodialysis system may include a dialysate flow path that includes a balancing circuit, a mixing circuit, and / or a directing circuit. The circuits may be defined in one or more cassettes. The fluid circuit may be at least partially spatially and / or thermally isolated from electrical components of the system. A gas supply is provided in fluid communication with the dialysate flow path and / or the dialyzer to force dialysate through the dialyzer and return blood to the patient.SELECTED DRAWING: Figure 61

In one aspect, a system includes a blood treatment machine; a dialyzer configured to be coupled to the blood treatment machine, the dialyzer including a dialyzer housing defining a blood inlet and a blood outlet; a bundle of hollow fibers within an interior of the dialyzer housing; a pumping device drivable to force blood received from the blood inlet through lumens of the bundle of hollow fibers and out the blood outlet; a dialysate inlet port in fluid communication with a dialysate flow path that includes space in the interior of the dialyzer housing between the bundle of hollow fibers; and a dialysate outlet port in fluid communication with the dialysate flow path. The system further includes a fluid conditioning system configured to (i) prepare and supply fresh dialysate to the dialyzer via the dialysate inlet port, and (ii) receive spent dialysate from the dialyzer via the dialysate outlet port, recycle the spent dialysate, and supply the recycled dialysate to the dialyzer via the dialysate inlet port.

The present application belongs to the technical field of peritoneal dialysis, and provides an automatic peritoneal dialysis device, which comprises a shell placed on a support table, the upper end of the shell is provided with a control console and a placing plate for placing a dialysate bag, the upper end of the shell is fixed with a liquid hanging rod for hanging a plurality of liquid supplement bags, the shell is divided into left and right two chambers by a partition plate, the connecting end of the dialysate bag is inserted into one end of an elastic water bag arranged in the left chamber, and the elastic water bag is provided with an adjusting structure for adjusting the capacity of the elastic water bag, the adjusting structure for adjusting the capacity of the elastic water bag can adjust the total amount of single dialysate flowing into the body according to the patient's own condition, the switching structure is arranged to automatically change the liquid, thereby reducing the liquid changing operation burden of the patient and nursing staff, and the peristaltic pump is arranged to adjust the flow and the size of the flow rate of the dialysate flowing into the patient's body.

This invention discloses a blood purification device and its usage method, relating to the field of medical device technology. A first housing and a second housing directly or indirectly form a hollow inner cavity and are capable of sliding relative to each other along the axial direction. During blood purification, blood flows through the fibrous membrane bundle, while dialysate flows through the inner cavity formed by the first and second housings, resulting in substance exchange between the blood and dialysate. When the fibrous membrane bundle becomes blocked, the first and second housings separate and move relative to each other along the axial direction. The fibrous membrane bundle is elastic, causing it to stretch. The shape of the micropores on the sidewalls of each membrane tube changes, allowing some of the blocking proteins to be squeezed out. When the length of the membrane bundle is restored, the size of the micropores on the sidewalls of each membrane tube is larger than in the initial state, further eliminating the blockage.

The present disclosure relates to a method comprising: determining a dialysis treatment time of a patient; receiving a dialysate flow rate from at least one sensor of the dialysis machine, the dialysate comprising bicarbonate pumped from a bicarbonate source, the bicarbonate source having an initial bicarbonate amount; and predicting that the amount of bicarbonate remaining in the bicarbonate source does not exceed a threshold at the end of the dialysis treatment; and in response, determining that the clearance value during the treatment is currently above or will be above the clearance threshold; and sending instructions to a balancing system to reduce the dialysate flow rate to a reduced flow rate capable of reducing the rate at which bicarbonate is pumped out of the bicarbonate source while maintaining the clearance value of the treatment not below the clearance threshold.

The current invention relates to a peritoneal dialysis filter device, which comprises a housing comprising a first port and a second port, and a hollow fibre membrane formed from hollow hydrophilic fibres within the housing. When in use, a dialysate from a subject enters the filter device through the first port and exits via the second port in an outflow direction, and a regenerated dialysate from a sorbent system enters the filter device through the second port and exits via the first port in an inflow direction. Also disclosed herein is a peritoneal dialysis system comprising said filter device, a method for controlling dialysate flow in a peritoneal dialysis system, and a haemodialysis device.

The invention relates to the technical field of hemodialysis, in particular to a hemodialysis liquid regulation and control method for blood glucose concentration balance, which specifically comprises the following steps: acquiring an initial insulin sensitivity index of a patient before dialysis; setting a blood glucose threshold interval and a dialysate flow velocity interval; the blood sugar concentration of the patient is monitored in real time in the dialysis process; matching the real-time blood glucose concentration with the blood glucose threshold interval to determine a corresponding dialysate flow velocity interval; performing dynamic adjustment on the basis of the real-time blood glucose concentration; the blood glucose concentration is pre-judged based on the real-time blood glucose concentration, so that the type and the flow velocity of dialysate are regulated and controlled; therefore, in the hemodialysis process, different patients can be more accurately adapted, and accurate regulation and control of the blood sugar concentration can be achieved.

A portable hemodialysis system is provided that includes a dialyzer, a closed-loop blood flow path, a closed-loop dialysate flow path, a blood pump, and a pair of dialysate pumps. The processor controls the flow of blood through the blood flow path, and the processor controls the flow of dialysate through the dialysate flow path. Further, the processor stores a pre-programmed patient treatment plan in which the flow rate of dialysate through the dialysate flow path is reduced throughout the patient treatment to maximize the amount of urea removed by the sorbent filter. In an alternative embodiment, a processor stores a patient treatment plan in which the dialysate flow rate increases throughout the patient treatment. In still alternative embodiments, the processor stores a patient treatment plan in which the flow rate of dialysate through the dialysate flow path increases and decreases throughout the patient treatment.