67 results about "Dialysate flow" patented technology

The utility model relates to the field of medical instruments, in particular to a dilution system structure for hemodialysis, which comprises a front dilution loop, a rear dilution loop, a displacement liquid outlet, a dialyzer and a controller. Displacement liquid of the displacement liquid outlet flows into the dialyzer through the front dilution loop, and dialysate flowing out of the dialyzer and the displacement liquid of the displacement liquid outlet flow into a human body through the rear dilution loop; the front dilution loop comprises a front dilution displacement pump, and the rear dilution loop comprises a rear dilution displacement pump; the problems that existing hemodialysis synchronous mixing and diluting treatment effects are poor and flexibility is poor are solved. The operation modes of the front dilution replacement pump and the rear dilution replacement pump are changed through the connection mode of the front dilution loop and the rear dilution loop, and flexible adjustment of the dialysis mode is achieved; the hemodialysis treatment effect can be effectively improved by monitoring the hemodialysis process in real time and automatically adjusting the hemodialysis parameters according to the monitoring result.

The present invention discloses a hemodialysis fluid balance control method, device, electronic device, and medium, relating to the technical field of intelligent regulation. The hemodialysis fluid balance control method includes: in response to a patient experiencing a hypotensive event, determining whether the hypotensive event is caused by a hypoglycemic event; if the hypotensive event is caused by a hypoglycemic event, switching the patient's dialysate from a sugar-free dialysate to a sugar-containing dialysate; monitoring the patient's real-time blood glucose concentration; and controlling the dialysate flow rate during the patient's dialysis based on the real-time blood glucose concentration. The embodiments of the present application achieve the goal of reducing interference with hemodialysis while ensuring compensation for hypoglycemia.

A system includes an extracorporeal blood treatment device and a heat exchanger for heat exchange between dialysate flowing from the extracorporeal blood treatment device and permeate to be supplied to the extracorporeal blood treatment device. The extracorporeal blood treatment device and the heat exchanger are configured as separate devices.

The invention discloses a movable assistor for peritoneal dialysis, and relates to the technical field of peritoneal dialysis. The movable assistor for peritoneal dialysis comprises a bottom plate, a fixing rod is fixedly arranged on the top face of the bottom plate, the outer wall of the fixing rod is slidably sleeved with a lifting sleeve, a plurality of self-locking wheels are fixedly arranged on the bottom face of the bottom plate, and a lifting mechanism, a dialysis mechanism, a placing mechanism and a fixing mechanism are arranged above the bottom plate. The dialysis mechanism has the technical effects that the dialysis mechanism is composed of the monitoring part and the control part, an automatic monitoring and intelligent control system for the dialysis process is formed, two tray scales of the monitoring part can monitor the weight change of a dialysate container in real time, and the weight information is transmitted to the control calculator through a second data line; the two intelligent flow monitoring valves are installed at the bottom of the connecting pipe and can monitor the flow of dialysate in real time and transmit data through the first data line, and the calculator is controlled to analyze and process the received weight and flow information.

The utility model relates to a multifunctional infusion support for peritoneal dialysis, which comprises a support body, the support body comprises a first rod and a second rod, the second rod is telescopically matched with the first rod, the infusion support further comprises a shelving part, the shelving part is connected with the first rod, and a reference body is arranged on the shelving part. By arranging the first rod and the second rod, the height can be freely adjusted according to illness conditions, and the flow speed of dialysate can be conveniently controlled; the peritoneal dialysis waste liquid bag can be conveniently placed through the arrangement of the placing part, stumbling traction is reduced, infection factors are reduced, meanwhile, the brightness of peritoneal dialysis liquid can be identified through the arrangement of the reference body, and the quality of the peritoneal dialysis liquid can be rapidly evaluated.

The disclosure relates to systems and methods for increasing the functional capabilities of a sorbent-based dialysis system. The systems and methods allow for the mode of operation of the dialysis system to be switched between single pass mode and a sorbent based multi-pass mode by controlling an amount of water added to the dialysate between 0% to 100% of the dialysate flow rate.

The invention discloses a roll type diffusion dialysis membrane assembly and a preparation method thereof. The roll type diffusion dialysis membrane assembly comprises a cylinder body and a U-shaped pipe, the upper end of the straight pipe part of the U-shaped pipe is respectively connected with diffusion liquid and dialysis liquid inlet and outlet pipes; wherein an ion exchange membrane is arranged between a pair of diagonal straight pipe parts, two sides of the ion exchange membrane are respectively provided with a flow channel separation net, and the ion exchange membrane and the flow channel separation nets are tightly attached to each other to be spirally rolled into a barrel by taking the pair of diagonal straight pipe parts as the axis; the wound tail ends of the ion exchange membrane and the runner separation net are respectively fixed on the other pair of straight pipe parts; a space supported by the flow channel separation net forms a fluid channel and is always positioned on two sides of the ion exchange membrane, one side forms a diffusion liquid flow channel and is communicated with a pair of diffusion liquid inlet and outlet connecting pipes, and the other side forms a dialysate flow channel and is communicated with a pair of dialysate inlet and outlet connecting pipes; according to the invention, the problems of difficulty in arranging a liquid inlet / outlet and low mass transfer efficiency when a plurality of membrane modules with higher integration degree are used for common treatment are solved.

A method and a detection device for detecting blood in a dialysate flow of a dialysis machine during extracorporeal blood treatment.

The utility model discloses a difficult-to-break nano dialysis membrane which comprises a cylinder bin serving as a mounting carrier, a first liquid inlet pipe communicated with the interior of the cylinder bin is mounted at the top of the outer side of the cylinder bin, a base is mounted at the inner bottom of the cylinder bin, a discharge pipe is mounted in the center of the base, and a second liquid inlet pipe communicated with the interior of the cylinder bin is mounted at the bottom of the discharge pipe. And the bottom end of the discharge pipe extends to the position below the cylinder bin, and liquid inlet holes are evenly formed in the top of the outer side of the discharge pipe. The internal space of the cylindrical bin is divided into the spiral gap channel through the plurality of groups of stacked nano dialysis membrane tubes, and dialysate flows towards the central position of the cylindrical bin along the spiral gap channel after being injected into the cylindrical bin, so that the flowing path of the dialysate is increased, and the dialysate can flow through the spiral gap channel. Moreover, the effective contact time of the nano dialysis membrane tubes and dialysate is also prolonged, so that the hemodialyzer can realize an expected dialysis effect by using fewer nano dialysis membrane tubes, and the use cost of the hemodialyzer each time is reduced.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a strain measuring device which includes a load cell and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.

The application discloses a kind of roll type diffusion dialysis membrane module and preparation method thereof, including cylinder, U-shaped tube;U-shaped tube straight pipe part upper end is connected respectively with the inlet and outlet pipe of diffusion liquid and dialysate;Wherein, between a pair of diagonal straight pipe parts, ion exchange membrane is equipped, and both sides of ion exchange membrane are equipped with a flow channel screen, above the pair of diagonal straight pipe parts, by ion exchange membrane and flow channel screen, spiral is wound into cylinder by mutual close, and the end of ion exchange membrane and flow channel screen winding is fixed on another pair of straight pipe parts respectively;Space supported by flow channel screen constitutes fluid channel and is always located at both sides of ion exchange membrane, one side constitutes diffusion liquid flow channel and is connected with a pair of diffusion liquid inlet and outlet connector communication, the other side constitutes dialysate flow channel and is connected with a pair of dialysate inlet and outlet connector communication, the application solves the problem that liquid inlet and outlet are difficult to set when multiple membrane modules are commonly processed in higher integrated degree and mass transfer efficiency is lower.

An aspect of the disclosure relates to a dialysate regenerator for connecting to a dialysis apparatus, the dialysate regenerator including a regenerator inlet for receiving dialysate; a regenerator outlet for dispensing regenerated dialysate; a hydraulic circuit connected between the regenerator inlet and the regenerator outlet, and further including a fluid portioning system to divide a dialysate flow into uniform portions for sequential regeneration An aspect of the disclosure relates to a dialysis system including a dialysis apparatus including: a fresh dialysate input; a spent dialysate output; and the dialysate regenerator, wherein the regenerator inlet may be coupled to the spent dialysate output for receiving spent dialysate, and wherein the regenerator outlet may be coupled to the fresh dialysate input for dispensing regenerated dialysate.

A portable hemodialysis system is provided that includes: a dialyzer, a closed-loop blood flow path that transports blood from a patient to the dialyzer and back to the patient, and a closed-loop dialysate flow path that transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs that can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight of each reservoir, and therefore the level of the dialysate in each reservoir, is measured by a preferred level sensor having a lever arm, a load cell, and a tilt sensor. The load cell and the tilt sensor are electrically connected to a processor for sending force measurements and tilt measurements to the processor. The processor can analyze the tilt measurements to correct any inaccurate measurements of the load cell caused by tilt.

The disclosure relates to a method including determining a treatment time of a dialysis treatment for a patient, receiving, from at least a sensor of a dialysis machine, a dialysate flow rate, the dialysate comprising bicarbonate pumped out of a bicarbonate source, wherein the bicarbonate source has an initial amount of bicarbonate, and predicting that by end of the dialysis treatment no more than a threshold amount of bicarbonate will be left in the bicarbonate source, and in response, determining that a clearance value during the treatment is or will be higher than the threshold clearance value, and sending, to a balancing system, an instruction to reduce the dialysate flow rate to a reduced rate, wherein the reduced rate results in reducing a rate of bicarbonate pumped out of the bicarbonate source while maintaining a clearance value of the treatment at no less than the threshold clearance value.

To provide a method for adjusting the dialysate flow rate and a hemodialysis apparatus that can quickly adjust the dialysate flow rate to a desired flow rate. [Solution] The method for adjusting the dialysate flow rate 100 includes: a pump control value determination step in which a pump control value corresponding to a desired dialysate flow rate is determined based on a calibration value that shows the correlation between a desired dialysate flow rate and the pump control value of the circulation pump 92; a pump operation step in which the circulation pump is operated with the pump control value determined in the pump control value determination step; a difference calculation step in which the difference between the current dialysate flow rate and the desired dialysate flow rate is calculated; and a calibration value correction step in which the calibration value is corrected based on the difference calculated in the difference calculation step.

A method includes receiving, by a processor of a dialysis machine, a dialysate flow rate, a bicarbonate setting value, a signal from a pressure sensor configured to measure a pressure within a container, and a signal indicating a state of a fill valve; determining, based on the signal received from the pressure sensor and the state of the fill valve, fill parameters; determining a volume of the container based on at least two of the fill parameters; determining a depletion time in which the concentrate will be depleted from the container based on the volume of the container, the dialysate flow rate, and the bicarbonate setting value; determining, based on the depletion time, an amount of time remaining before the concentrate will be depleted from the container; and causing the dialysis machine to indicate the amount of time remaining before the concentrate will be depleted from the container.

The utility model relates to a directional feeding device for a dialyzer end cover, a dialysate flow opening of the end cover is of a circumferential protruding structure, the directional feeding device comprises a straight vibration feeding assembly, a static material channel assembly, an end cover transferring mechanism and an end cover directional mechanism, the static material channel assembly is arranged in the conveying direction of the straight vibration feeding assembly, and the end cover directional mechanism is arranged on the end cover transferring mechanism. The end cover transferring mechanism clamps and moves the end cover, and a stop block and a deflector rod in the end cover orientation mechanism are matched to limit the rotation angle of the dialysate flow opening, so that the dialysate flow opening is forcibly corrected to the preset direction. The end cover feeding device solves the problem that in the prior art, when end covers are fed, the directions of dialysate flow openings of the end covers are inconsistent. The device can greatly improve the production efficiency and reduce the time and cost of manual adjustment.

An organ preservation system having; an organ chamber with a perfusate reservoir, a pump arranged to circulate perfusate, from the reservoir and passes the perfusate through a dialysis filter, oxygenator, and temperature and pressure sensors prior to entering the chamber where an organ is perfused. The organ rests on the platform such that perfusate leaving the organ flows into the perfusate reservoir. The dialysis filter having permeable tubes which allow perfusate constituents to be exchanged with dialysate flowing through the dialysis filter. The dialysate pass through an ion exchange resin removing selected constituents or waste products from the dialysate by absorption by the ion exchange resin. Following waste absorption, the dialysate is recycled to the dialyzer to again remove waste. Removing waste products from the perfusate by dialysis followed by removal of the waste products from the dialysate with the exchange resin, enables dialysate reuse for extended duration.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient, to the dialyzer, and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. The hemodialysis system includes a hemodialysis machine and dialysate generator which are physically connectable to, and disconnectable from, one another. To connect the hemodialysis machine and dialysate generator together, both the hemodialysis machine and dialysate generator possess connectable and disconnectable electrical connectors and fluid connectors which are positioned and constructed to allow both a fluid and electrical connection between the two machines. The hemodialysis machine includes a processor and a user interface, preferably in the form of a touchscreen, that is capable of controlling both the functions of the hemodialysis machine and the dialysate generator.

Apparatus and methods for performing ex-vivo perfusion of an organ are disclosed. In one arrangement, an organ receiving unit (4) receives an ex-vivo organ and provides fluidic connections to a vasculature of the received organ. A first conduit system defines a perfusate flow circuit (21) including a flow path through the vasculature of the received organ. A perfusate pumping system (14) drives a circulatory flow of perfusate in the perfusate flow circuit and through the vasculature of the received organ. A second conduit system defines a dialysate flow circuit (22). A dialysate pumping system drives a circulatory flow of a dialysate in the dialysate flow circuit. A dialysis unit processes the perfusate using the dialysate, the dialysis unit comprising a membrane configured to contact the perfusate in the perfusate flow circuit on one side of the membrane and the dialysate in the dialysate flow circuit on the other side of the membrane. The membrane allows material to pass between the perfusate flow circuit and the dialysate flow circuit as a transmembrane flux.

The present invention aims to provide a dialysis apparatus with optimized placement and operability of the monitor unit. Furthermore, the present invention aims to provide a dialysis apparatus that reduces the burden on technicians in attaching blood circuits. [Solution] The dialysis apparatus comprises a housing 1 consisting of an electrical unit and a dialysate unit, a blood circuit connected to the patient through which blood and dialysate flow, an extracorporeal circulation unit 8 located on the front of the housing 1 and connected to the blood circuit, a dialyzer 2 located on the side of the housing, and a monitor unit 3 for operating each function and understanding the treatment status. Furthermore, the monitoring unit 3 is characterized by being positioned on the upper surface of the extracorporeal circulation unit as a deployable lid.

The present invention aims to provide an intelligent and safe peritoneal dialysis clamp that can detect and warn dialysis tubes, and can also intelligently adjust the size of the tubes and block the tubes. The present invention comprises an upper cover, a lower cover hingedly connected to the upper cover, the upper cover and the lower cover cooperate to form a limiting channel for the dialysis tube to pass through, the upper cover is sequentially provided with ultrasonic detection parts for detecting the gas in the tube along the dialysate flow direction, two groups of temperature detection components that fit the dialysis tubes, and a pipeline control component for adjusting the opening and closing of the dialysis tubes, a first squeezing seat is formed at one end of the upper cover, the lower cover is provided with a second squeezing seat that cooperates with the pipeline control component to squeeze the dialysis tube, and the lower cover is rotatably connected to a manual lever that cooperates with the first squeezing seat to close the pipeline. The present invention is applied to the technical field of peritoneal dialysis clamps.

The present disclosure relates to a dialysis device that efficiently performs a pre-flushing operation. In the pre-flushing operation, the venous passage (3A) is kept in a state of being connected to the upper part. In a state in which a dialysate supply on-off valve (V9) is closed and a dialysate collection on-off valve (V10) is opened, a pressurization means operates and causes a pre-flush liquid to flow into a dialyzer (2) from a dialysate collection passage (4B), whereby the pre-flush liquid in a dialysate flow path (12b) is reversely filtered in a hollow fiber (12) (blood purification membrane), and a blood flow path (12a) is filled with the pre-flush liquid and pressurized (b). Next, after closing the dialysate collection on-off valve (V10), a decompression means depressurizes the dialysate circuit (4) to generate a pressure difference between the blood circuit (3) and the dialysate circuit (4), and when a dialysate supply on-off valve (V9) provided in the dialysate supply path (4A) is opened, the pre-flush liquid in the blood flow path (12a) is positively filtered in the hollow fibers (12) by the pressure difference, and the pre-flush liquid is discharged from the blood flow path (12a) by the hollow fibers (12). The pre-flush liquid in the blood flow path (12a) flows into the dialysate flow path (12b), and air bubbles B (c) remaining above the dialysate flow path (12b) are removed.

A renal failure blood therapy system includes a memory device storing a therapy target for a patient. The system also includes a processor configured to receive the therapy target for the patient, receive a desired solute concentration for the patient, and apply the therapy target and the desired solute concentration as inputs to an optimization routine. The processor is also configured to execute the optimization routine to determine at least one dialysis therapy prescription specifying at least a dialysis therapy duration, a dialysis therapy frequency, and at least one of a dialysis therapy blood flow rate or a dialysis therapy dialysate flow rate. The processor is further configured to display the at least one dialysis therapy prescription for confirmation or selection by a clinician and transmit the selected or confirmed dialysis therapy prescription to a dialysis machine for a subsequent dialysis treatment for the patient.

The application discloses a peritoneal dialysis catheter assembly capable of preventing fibrin clot blockage, which comprises a drainage tube and a cleaning rod. The drainage tube is internally provided with an axially extending drainage cavity, and the drainage tube comprises an insertion section and a guide section, and the insertion section is provided with a plurality of drainage holes; the cleaning rod is arranged in the drainage cavity, the cleaning rod is coaxially arranged with the drainage tube, and the cleaning rod is provided with a plurality of blades. By means of the energy of the dialysate flow, the blades guide the local deflection and acceleration of the flow direction, induce continuous turbulence and vortex near the inner wall of the drainage cavity, the shear force in the turbulence area can effectively strip the fibrin clot adhered to the cavity wall, and the stirring action of the vortex prevents the deposition of new clots on the surface of the cavity wall. The arrangement of the plurality of blades can generate vortexes with alternating directions at different axial positions, avoid the single stable mode of the flow field and reduce the scouring efficiency, so that the unobstructed state of the drainage cavity can be maintained for a long time without relying on external power.

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and / or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and / or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and / or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

A blood purification apparatus is provided which returns blood in a blood circuit to a body. The blood purification apparatus includes a blood circuit and a dialysate circuit connected via a blood purifier; an air introduction path connected to the dialysate circuit; an air introduction portion provided to the dialysate circuit or the air introduction path and introducing air into the dialysate circuit via the air introduction path to bring the dialysate circuit to a positive pressure; and a control device which controls the air introduction portion in a manner that dialysate flows from the dialysate circuit to the blood circuit, and controls the blood circuit and the dialysate circuit in a manner that blood in the blood circuit and the blood purifier is returned to the body by causing the dialysate to flow from the dialysate circuit to the blood circuit.

One aspect of this disclosure relates to a dialysate regenerator for connection to a dialysis apparatus, the dialysate regenerator including a regenerator inlet for receiving dialysate; a regenerator outlet for dispensing regenerated dialysate; a hydraulic circuit connected between the regenerator inlet and the regenerator outlet; and a fluid dispensing system for dividing the dialysate flow into uniform portions for sequential regeneration. Another aspect of this disclosure relates to a dialysis system including a dialysis apparatus comprising: a fresh dialysate inlet; a used dialysate outlet; and a dialysate regenerator, wherein the regenerator inlet can be connected to the used dialysate outlet to receive used dialysate, and wherein the regenerator outlet can be connected to the fresh dialysate inlet to dispense regenerated dialysate.

Provided are a method for adjusting a dialysate flow rate and a hemodialyzer capable of quickly completing adjustment of the dialysate flow rate to a desired flow rate. A method for adjusting a dialysate flow rate (100) includes: a pump control value determination step of determining a pump control value corresponding to a desired dialysate flow rate, on the basis of a calibration value indicating a correlation between the desired dialysate flow rate and a pump control value of a circulation pump (92); a pump operation step of operating the circulation pump with the pump control value determined in the pump control value determination step; a difference calculation step of obtaining a difference between a current dialysate flow rate and the desired dialysate flow rate; and a calibration value correction step of correcting the calibration value on the basis of the difference calculated in the difference calculation step.