151 results about "Dialysis membranes" patented technology

The invention belongs to the field of carbon nanomaterials, and provides a method for preparing a carbon quantum dot material doped with elements such as silicon and aluminum by oxidative depolymerization and stripping of coal gangue. Comprising the steps of screening and matching of coal gangue, oxidative depolymerization stripping, centrifugal dialysis membrane filtration and modification, drying and the like, raw materials and all the steps are specifically set, and the particle size or fluorescence performance of fluorescent carbon dots can be specifically selected and set according to selective oxidative depolymerization stripping conditions. The main particle size of the prepared multi-inorganic-element doped carbon quantum dot material is kept within the range of 1.5-2.0 nm, the structure is stable, the optical performance also meets the requirements, and the material can be further modified and is expected to be applied to the fields of photovoltaic equipment, biological imaging, photocatalytic degradation of organic pollutants or sensing and the like.

The invention belongs to the technical field of membrane separation, and discloses a preparation method of a double-layer hemodialysis membrane capable of releasing negative ions. The preparation method takes polyether sulfone (PES) as a membrane material and a tourmaline-graphene oxide (TM-GO) composite material as an additive, and comprises the following steps: preparing the tourmaline-graphene oxide (TM-GO) composite material; preparing a PES membrane casting solution and a membrane casting solution formed by blending PES and TM-GO; carrying out vacuum defoaming treatment on the membrane casting solution, and then blade-coating a double-layer membrane on a glass plate; and putting the blade-coated membrane into a coagulating bath formed by mixing N, N-dimethylformamide (DMF) and water, and carrying out phase inversion treatment, so as to obtain the double-layer hemodialysis membrane capable of releasing negative ions. The prepared double-layer hemodialysis membrane capable of releasing the negative ions has an excellent toxin removing effect, meanwhile, the negative ions can be released to enter a human body along with blood flow while hemodialysis treatment is conducted, and the membrane is endowed with the anti-oxidation function.

The invention discloses a hemodialysis membrane with a self-anticoagulation function and a preparation method of the hemodialysis membrane. The hemodialysis membrane with the self-anticoagulation function is obtained by modifying natural polymer fibrin, polydopamine and a sulfonic acid type polymer solution. The hemodialysis membrane is any one or more of a polysulfone membrane, a polyether sulfone membrane, a polyvinylidene fluoride membrane, a polymethyl methacrylate membrane, a polyacrylonitrile membrane, a polyamide membrane, a polyvinyl alcohol membrane, a cellulose acetate membrane and a polypropylene membrane. The invention is used for treating acute and chronic kidney diseases, has good biocompatibility, and shows good blood compatibility in the aspects of inhibiting protein adsorption, platelet adsorption and red blood cell adsorption, reducing hemolysis rate, prolonging blood coagulation time and the like. And the risk of thrombosis caused by improper use of an anticoagulant in a continuous anticoagulation treatment process can be effectively avoided, and the living quality and the survival time of a hemodialysis patient are effectively improved and prolonged.

1. Name of the design product: In-vehicle Dialysis Membrane Vent Aroma Diffuser (C-251). 2. Use of the design product: It is used to hold fragrance substances and clip it at the air outlet of the car air conditioner for use and fragrance diffusion. 3. Design key points of the design product: lies in the shape. 4. The picture or photo that best shows the design key points: Perspective View 1.

The invention discloses an antibacterial nanofiber hemodialysis membrane and a preparation method thereof, and relates to the technical field of dialysis membranes, and the preparation method comprises the following steps: mixing a chitosan derivative, heparin, dopamine, an unsaturated monomer and an initiator in a DMF / phosphate buffer mixed solution to obtain a surface treating agent; taking the polyethersulfone nanofiber membrane as a supporting layer, dipping in a surface treating agent, and performing UV irradiation to form a functional layer, thereby obtaining the dialysis membrane. The preparation method comprises the following steps: compounding phenanthroline cerium triacrylate hybridized CeO2 with N-vinyl pyrrolidone, sodium p-styrenesulfonate and lauryl methacrylate to obtain an unsaturated monomer, compounding the unsaturated monomer with a chitosan derivative, heparin and dopamine to prepare a surface treating agent, impregnating a polyether sulfone nanofiber membrane, and carrying out irradiation curing to form a functional layer. The prepared hemodialysis membrane has efficient anticoagulation and broad-spectrum antibacterial properties, high permeability, low protein adsorbability and long-term stability.

The invention provides a resource recycling method of ammonium-containing waste sulfuric acid, which comprises the following steps: (1) respectively introducing a solvent and ammonium-containing waste sulfuric acid into two sides of a dialysis membrane for diffusion dialysis treatment, and respectively obtaining a sulfuric acid solution and an acidic ammonium sulfate solution on two sides of the dialysis membrane; and (2) carrying out bipolar membrane electrolysis treatment on the acidic ammonium sulfate solution to obtain ammonia water and ammonium-containing sulfuric acid. According to the method disclosed by the invention, sulfuric acid and ammonium ions (converted into ammonia water) in the ammonium-containing waste sulfuric acid can be efficiently and greenly recovered, the obtained ammonium-containing sulfuric acid can also be repeatedly recovered, and resource recovery of the ammonium-containing waste sulfuric acid is realized under the condition of ensuring low cost.

The application discloses a kind of hydrophilic polyvinylidene fluoride oil-water separation membranes and preparation method thereof, belong to oil-water separation membrane technical field.The preparation method steps include: with 2,2-dimethoxy-2-phenyl acetophenone as photo initiator, 3,6-dioxane-1,8-octane dithiol and polyethylene glycol diacrylate as modifier, by photo initiation mercapto-olefin gradually polymerization method is modified to alkali treated PVDF membrane, and hydrophilic polyvinylidene fluoride oil-water separation membrane is prepared.The application is grafted to PVDF separation membrane surface by photo initiation mercapto-olefin gradually polymerization method, and hydrophilic separation membrane is obtained.The preparation method provided by the application has the characteristics of simple process, low cost and the like, and the prepared hydrophilic membrane can be further developed and utilized as sewage treatment separation membrane, hemodialysis membrane.

The present disclosure relates to a membrane with significantly increased selectivity for use in hemodialysis applications, wherein the membrane is coated with chondroitin. The membrane can be obtained by contacting a base membrane, which for example comprises a blend of i) a polysulfone, polyethersulfone or polyarylethersulfone and ii) polyvinylpyrrolidone, to a solution of chondroitin followed by e-beam radiation. The disclosure further relates to a process for producing the selective hemodialysis membrane, and to a method of increasing the selectivity of a membrane. The disclosure further relates to a filtration / diffusion device comprising such membrane.

The invention discloses a roll type diffusion dialysis membrane assembly and a preparation method thereof. The roll type diffusion dialysis membrane assembly comprises a cylinder body and a U-shaped pipe, the upper end of the straight pipe part of the U-shaped pipe is respectively connected with diffusion liquid and dialysis liquid inlet and outlet pipes; wherein an ion exchange membrane is arranged between a pair of diagonal straight pipe parts, two sides of the ion exchange membrane are respectively provided with a flow channel separation net, and the ion exchange membrane and the flow channel separation nets are tightly attached to each other to be spirally rolled into a barrel by taking the pair of diagonal straight pipe parts as the axis; the wound tail ends of the ion exchange membrane and the runner separation net are respectively fixed on the other pair of straight pipe parts; a space supported by the flow channel separation net forms a fluid channel and is always positioned on two sides of the ion exchange membrane, one side forms a diffusion liquid flow channel and is communicated with a pair of diffusion liquid inlet and outlet connecting pipes, and the other side forms a dialysate flow channel and is communicated with a pair of dialysate inlet and outlet connecting pipes; according to the invention, the problems of difficulty in arranging a liquid inlet / outlet and low mass transfer efficiency when a plurality of membrane modules with higher integration degree are used for common treatment are solved.

The purpose of the present invention is to provide a dialysis membrane capable of removing CPPs while suppressing a reduction in minerals and capable of being suitably used for blood processing including the adsorption of CPPs. The present invention pertains to a dialysis membrane comprising a hollow fiber membrane or a semipermeable membrane which is a flat membrane, wherein said dialysis membrane is used for blood processing including the adsorption of calciprotein particles which are complexes of calcium phosphate and proteins, and has a compound (A) in which a film-forming polymer constituting the semipermeable membrane has, in a portion other than terminals of a main chain, at least one electron-donating group selected from the group consisting of an amino group, a carboxy group, a phosphoric acid group, a phosphono group, a phosphino group, and a thiol group, and / or has, separately from the semipermeable membrane, at least one electron-donating group selected from the group consisting of an amino group, a carboxy group, a phosphoric acid group, a phosphono group, a phosphino group, and a thiol group.

The invention discloses a protein / polysaccharide composite dialysis membrane based on in-situ loaded lanthanum carbonate and application of the protein / polysaccharide composite dialysis membrane, a lanthanum carbonate loaded protein / polysaccharide composite aggregate is used for modifying a porous filter membrane, and the dialysis membrane with a lanthanum carbonate loaded protein / polysaccharide self-assembled membrane as a compact skin layer and the porous filter membrane as a supporting layer is formed. By integrating a membrane separation mechanism of hemodialysis and an adsorption principle of blood perfusion, the skin layer of the dialysis membrane has molecular sieve separation and chemical adsorption functions, efficient removal of molecular uremic toxins (phosphorus, creatine liver, bilirubin, p-cresol sulfate and indol sulfate) with different sizes is synergistically realized, macromolecular proteins in blood are effectively intercepted by pore size screening, and the dialysis membrane has the advantages of simple structure, low cost and high efficiency. According to the present invention, by using the adsorption effect of the functional group on the surface of the membrane, the high removal rate on the protein-bound urotoxin is achieved, the high removal effect on phosphorus is particularly achieved, the blood compatibility is considered, the large-scale preparation is easily achieved, and the new idea is provided for the development of the high-performance blood purification material.

The invention discloses an electrophoresis and dialysis integrated device, and designs a multistage dialysis and electrophoresis composite separation device driven by an electric field, a separation pool is designed into a plurality of multistage liquid boxes which are mutually independently communicated, and a positive electrophoresis electrode and a negative electrophoresis electrode are oppositely arranged on the inner sides of the outermost side walls of the two liquid boxes on the outermost side of the separation pool. A driving electric field from one end to the other end of the separation tank is formed after electrification, separated dialysis membranes are arranged on the communicating surfaces of every two liquid boxes, the dialysis membranes among the multi-stage liquid boxes are provided with multi-stage apertures according to requirements, charged particles of sample liquid migrate in the direction of the electric field under the action of the electric field, and when the charged particles pass through the dialysis membranes with different apertures, the charged particles are separated from the sample liquid. Molecules larger than the aperture are blocked, and molecules smaller than the aperture can continue to migrate to a next-stage liquid box, so that rapid molecular cascade separation under the driving of an electric field is realized; compared with existing electrophoresis, gel is not used, dyeing is not needed, and a sample is easy to recover; compared with traditional dialysis, the separation speed is greatly increased.

The method of obtaining modified carbon quantum dots by N-substitution of compounds from the coumarin group, consists, according to the invention, in the fact that the carbon quantum dots, obtained by carbonisation of biomass constituting, inter alia, 1 biologically active substance having free carboxyl groups, are modified by the formation of an amide bond in an aqueous medium, under normal conditions, and then purified using dialysis membranes. During grafting, the ratio of dye to EDC is 1 to 1.1. The invention also relates to the carbon quantum dots with a fluorescence emission spectrum in the range 380- 800 nm, obtained by this method.

The invention relates to the field of immune assessment, in particular to an end-stage nephropathy dialysis patient immune assessment method, which comprises the following steps: preparing a database for storing assessment scores of various parameters; preparing a convolutional neural network, and collecting immune intensity change data before and after dialysis of a patient population as a training library; immune intensity change data before and after dialysis under experimental conditions are obtained under laboratory conditions, the data under the experimental conditions are input into a convolutional neural network, and the convolutional neural network is used for training according to a preset mixing proportion rule and outputting a dialysis cause compensation function; data such as demographic characteristics, basic diseases, representative immune activation state data, representative immune senescence state data and dialysis frequency of a patient are collected, a total score is calculated based on a database and a dialysis cause compensation function, and the immunocompetence of the patient is evaluated. By adopting the method, the immunocompetence fluctuation caused by imperfect biocompatibility of the dialysis membrane can be compensated in immune assessment.

The invention discloses a preparation method of a hollow fiber dialysis membrane with precise gradient holes, which comprises the following steps: preparing a spinning solution and 0.1-0.5 wt% of sodium citrate core solution, injecting the spinning solution with the temperature of 50-54 DEG C and the core solution with the temperature of 40-44 DEG C into a spinning head to prepare a hollow fiber prototype, forming an initial fiber in an air section with the temperature of 36-40 DEG C, the RH of 60-70% and the diameter of 600-1000mm, and performing outer coagulating bath treatment at the temperature of 20-24 DEG C and inner coagulating bath treatment at the temperature of 40-44 DEG C to obtain the hollow fiber dialysis membrane with the precise gradient holes. And cleaning, drying, collecting and assembling after drafting. According to the method, the dialysis membrane with the inner diameter of 190-210 mu m, the wall thickness of 35-40 mu m, the inner surface aperture of 3-8 nm, the outer surface aperture of 50-200 nm and the radial aperture gradient larger than or equal to 4.5 nm / mu m is prepared by regulating and controlling parameters such as an air section and a coagulating bath, and the urea clearance rate gt is achieved. The albumin leakage rate is 1t; and the solute removal efficiency and the mechanical strength are balanced.

A process for producing a phenolic monomer product comprising depolymerizing a recycled polymeric material to obtain a depolymerized mixture comprising phenolic monomers and purifying the depolymerized mixture. The polymeric material comprises at least one PAES polymer and at least one additive, and the PAES polymer preferably comprises a backbone comprising at least one sulfone recurring unit, a first end group being a halide, and a second end-capped group, preferably selected from alkoxy groups and / or phenoxy groups. The additive comprises a polyalkylene oxide and / or a polyvinylpyrrolidone (PVP). A purity of at least 95 wt% of phenolic monomers can be achieved in the product. In particular embodiments in which a recycled hemodialysis membrane comprises a polyethersulfone and PVP, a purity of at least 98 wt% based on the total weight of the phenolic monomer product of 4,4'-sulfonyl phenolic monomers can be achieved after depolymerisation and phenolic monomer purification.

The invention belongs to the technical field of medical equipment, and particularly discloses a clinical hemodialysis device and a using method thereof.The clinical hemodialysis device comprises a dialysis box, and a dialysis assembly is arranged on one side of the dialysis box; the dialysis assembly comprises a dialyzer, a liquid inlet pipe, a liquid outlet pipe, a dialysate inlet, a dialysate outlet, a dialysis membrane, an inner partition plate and an adjusting structure. By means of the flow guiding structure, flow guiding can be conducted when blood enters the dialysis cavity, the situation that blood easily flows in a deviated mode after entering the dialysis cavity, so that no blood passes through the surface of a dialysis membrane on one side, the blood and dialysis efficiency is affected is prevented, the treatment duration is shortened, complications are reduced, and the treatment effect is improved by heating the blood. Therefore, the blood is kept at the temperature acceptable by the human body, the comfort of a patient during treatment is improved, and the dialysis treatment is safely and efficiently carried out.

The utility model discloses a difficult-to-break nano dialysis membrane which comprises a cylinder bin serving as a mounting carrier, a first liquid inlet pipe communicated with the interior of the cylinder bin is mounted at the top of the outer side of the cylinder bin, a base is mounted at the inner bottom of the cylinder bin, a discharge pipe is mounted in the center of the base, and a second liquid inlet pipe communicated with the interior of the cylinder bin is mounted at the bottom of the discharge pipe. And the bottom end of the discharge pipe extends to the position below the cylinder bin, and liquid inlet holes are evenly formed in the top of the outer side of the discharge pipe. The internal space of the cylindrical bin is divided into the spiral gap channel through the plurality of groups of stacked nano dialysis membrane tubes, and dialysate flows towards the central position of the cylindrical bin along the spiral gap channel after being injected into the cylindrical bin, so that the flowing path of the dialysate is increased, and the dialysate can flow through the spiral gap channel. Moreover, the effective contact time of the nano dialysis membrane tubes and dialysate is also prolonged, so that the hemodialyzer can realize an expected dialysis effect by using fewer nano dialysis membrane tubes, and the use cost of the hemodialyzer each time is reduced.

This invention discloses a testing fixture for the water contact angle of hollow fiber membranes, including a support assembly, a carrier assembly, an adhesive assembly, a display assembly, and a lifting assembly. The support assembly is symmetrically arranged on both sides, and each of the two sets of support assemblies has a carrier assembly for placing the component on its surface. The carrier assembly has an adhesive assembly for positioning the material on its surface. This invention solves the problem of the lack of an effective method to evaluate the hydrophilicity and hydrophobicity of the inner surface of hollow fiber dialysis membranes by coordinating the components, carrier assembly, adhesive assembly, display assembly, lifting assembly, and stopwatch. The testing method is simple and effective, requiring no special tools or equipment. This testing method and fixture can meet the requirements for rapid evaluation of the contact angle of the inner surface of hollow fiber membranes at the micron level. The testing method is simple, the testing cost is low, and the test results have high reliability. Therefore, it can be used as an evaluation tool for the hydrophilicity and hydrophobicity of the inner surface of hollow fiber membranes.

To provide a stable dialysis using a biological monitoring data and the like by appropriately suppressing a decrease in blood pressure during a dialysis treatment.SOLUTION: A dialyzer includes: an extracorporeal circulation blood passage; a dialysis liquid passage; a dialysis membrane provided to partition a part of the extracorporeal circulation blood passage and the dialysis liquid passage; circulation blood amount change rate measurement means for measuring the circulation blood amount change rate ΔBV of the patient; and water removal means for removing a part of the dialysis liquid flowing in the dialysis liquid passage to outside of the system to remove water in the blood from the extracorporeal circulation blood passage to the dialysis liquid passage. The water removal means is controlled such that the water removal speed at the end of the dialysis process is at a constant speed. The water removal means is controlled such that the water removal speed decreases when an inclination of a graph showing a change over time of the circulation blood amount time change rate ΔBV becomes a predefined first value or less in the period other than the end of the process.SELECTED DRAWING: Figure 2

The invention discloses a preparation method of an oxapyrazine capsule, which comprises the following steps: 1) preparing a primary suspension: dissolving a polymer carrier material in an organic solvent, and dissolving oxapyrazine in the solution to obtain an oil phase; adding a surfactant into the purified water to obtain a water phase; dropwise adding the oil phase into the water phase, and stirring by using a stirrer to prepare a primary suspension; 2) preparing a nano suspension: performing emulsification treatment by an ultrasonic processor to prepare the nano suspension; removing the organic solvent in a manner of reduced pressure evaporation or dialysis with a dialysis membrane to leave an oxapyrazine nanoparticle suspension; 3) preparation of the oxapyrazine capsule: drying the nano suspension prepared in the step 2) by a freeze drying method or a spray drying method to obtain oxapyrazine nano particles in a solid powder form, and the final average particle size is 300 + / -60nm; and filling a capsule shell with the prepared oxapyrazine nanoparticle powder to prepare the oxapyrazine capsule. The sustained release time of the oxapyrazine capsule prepared by the method is obviously prolonged.

The application discloses a kind of roll type diffusion dialysis membrane module and preparation method thereof, including cylinder, U-shaped tube;U-shaped tube straight pipe part upper end is connected respectively with the inlet and outlet pipe of diffusion liquid and dialysate;Wherein, between a pair of diagonal straight pipe parts, ion exchange membrane is equipped, and both sides of ion exchange membrane are equipped with a flow channel screen, above the pair of diagonal straight pipe parts, by ion exchange membrane and flow channel screen, spiral is wound into cylinder by mutual close, and the end of ion exchange membrane and flow channel screen winding is fixed on another pair of straight pipe parts respectively;Space supported by flow channel screen constitutes fluid channel and is always located at both sides of ion exchange membrane, one side constitutes diffusion liquid flow channel and is connected with a pair of diffusion liquid inlet and outlet connector communication, the other side constitutes dialysate flow channel and is connected with a pair of dialysate inlet and outlet connector communication, the application solves the problem that liquid inlet and outlet are difficult to set when multiple membrane modules are commonly processed in higher integrated degree and mass transfer efficiency is lower.

The application discloses an ultrafiltration permeation regulation method and device based on a gradient sponge structure dialysis membrane and relates to the technical field of hemodialysis. An intelligent response membrane assembly containing a nonlinear aperture gradient is constructed; a signal is collected and a concentration polarization critical index is calculated; when the threshold value is exceeded, a multi-frequency coupling pulse control instruction containing a mechanical resonance excitation waveform and a phase reverse matching osmotic pressure oscillation waveform is generated; mechanical resonance excitation is applied to the blood side to induce membrane layer micro-breathing deformation, and an osmotic pressure oscillation waveform is injected into the dialysate side to form a reverse solute diffusion field; microgel deformation feedback signals are monitored in real time, waveform parameters are dynamically adjusted, and the concentration polarization critical index is returned to a safe interval until the ultrafiltration flux is adaptively regulated. The device comprises an intelligent gradient membrane assembly, a fluid power regulation module, an osmotic pressure wave generation module, a sensing feedback array and a central processing unit, can effectively inhibit membrane pollution and concentration polarization, and improves the system operation stability.

The invention discloses a bionic modification method of a hemodialysis membrane and application of the bionic modification method, and belongs to the technical field of medical materials.The method comprises the steps that vinylbenzylamine and vinyltriethoxysilane are dissolved in triethyl phosphate to be stirred, an initiator azodiisobutyronitrile is added, and heating polymerization is conducted to obtain a polymer [P (EP-VTES)]; carrying out amidation reaction to form a gallic acid functional polymer (Ga-EPTES); ga-EPTES is cross-linked to the surface of a polyethersulfone membrane in a monomolecular layer form, and the hemodialysis membrane with the functions of resisting oxidation and removing free DNA is prepared. According to the bionic modification method of the hemodialysis membrane, the functional limitation and modification defects of a traditional blood purification material are broken through, an efficient, safe and large-scale solution is provided for sepsis treatment, and the bionic modification method has scientific value and clinical transformation potential.

This invention discloses a method for preparing a blood purification dialysis membrane and its application, relating to the field of materials preparation technology. The method includes the following steps: S1, dissolving polyacrylonitrile powder in N-N-dimethylformamide solvent to obtain a PAN spinning solution; S2, spinning the PAN spinning solution using electrospinning to obtain a PAN nanofiber membrane; S3, depositing a multi-walled carbon nanotube solution into the interfiber gaps of the PAN nanofiber membrane to obtain a composite PAN nanofiber membrane; S4, subjecting the composite PAN nanofiber membrane to hot-pressing treatment to obtain the blood purification dialysis membrane. By combining electrospinning with multi-walled carbon nanotube deposition and hot-pressing processes, a composite membrane with a gradient pore size structure is constructed. This effectively removes small and medium-sized toxins while selectively retaining large-molecule proteins, solving the technical challenges of wide pore size distribution and difficulty in balancing toxin removal and protein retention in traditional dialysis membranes. It offers the advantages of precise membrane structure control and improved blood purification efficiency.

The present application relates to a kind of saffron red base long wave carbon dots preparation method and its application in anti-counterfeit fluorescent ink, purpose is to solve carbon dots in anti-counterfeit ink encryption mode single, in MnO4 ‑ The detection range is narrow, and the detection limit is high in the detection technology, and the technical scheme is as follows: ultrasonic dissolution of safflower red T and oxalic acid in deionized water at room temperature; high-pressure reactor high-temperature heating reaction, natural cooling to room temperature, filtering, then dialysis membrane dialysis to obtain carbon dots aqueous solution, freeze-drying to obtain carbon dots powder (O-CDs), safflower red base long wave carbon dots and application in metal ion detection and fluorescent anti-counterfeit ink.The present application uses safflower T containing conjugated system as precursor, and successfully prepares carbon dots powder (O-CDs) by doping oxalic acid, which has good biocompatibility, wavelength independence, high stability, low biological toxicity and other advantages, and can be successfully applied to label-free detection and double anti-counterfeiting of MnO4 ‑ .

The invention belongs to the technical field of ceramic precursors, and particularly relates to a silicon-boron-carbon-nitrogen ceramic precursor with a main chain containing alkynyl and a preparation method of the silicon-boron-carbon-nitrogen ceramic precursor. Comprising the following steps: (1) dropwise adding an n-butyllithium solution into an ether solvent, stirring, continuously dropwise adding trichloroethylene, and reacting to obtain an alkynyl dilithium salt turbid solution; (2) adding boron trichloride into the alkynyl dilithium salt turbid solution to carry out primary dechlorination polycondensation reaction, and dropwise adding dichlorosilane to carry out secondary dechlorination polycondensation reaction after the reaction is completed; (3) adding hexamethyldisilazane into the system in the step (2) to carry out an end-capping reaction, collecting supernate after the reaction is finished, and distilling at normal pressure to remove the solvent, so as to obtain a silicon-boron-carbon-nitrogen ceramic precursor crude product; and (4) dissolving the silicon-boron-carbon-nitrogen ceramic precursor crude product in an organic solvent, carrying out dialysis treatment, and carrying out atmospheric distillation on the solution in a dialysis membrane to remove the solvent so as to obtain the silicon-boron-carbon-nitrogen ceramic precursor with the main chain containing alkynyl, and the ceramic yield of the silicon-boron-carbon-nitrogen ceramic precursor in the high-temperature ceramization process can reach more than 70%.

The invention discloses a modified cellulose acetate dialysis membrane and a preparation method thereof.The preparation method comprises the following steps that after a cellulose acetate membrane is hydrolyzed for 1 min, the acetyl part of the cellulose acetate membrane is removed, then the cellulose acetate membrane with the acetyl part removed is subjected to an oxidation reaction, and the cellulose acetate membrane with the acetyl part removed is obtained; a selective oxidation catalyst A and / or a co-catalyst B are / is used in the oxidation reaction process, and an oxidant C is one of sodium hypochlorite, sodium chlorite, calcium hypochlorite, hydrogen peroxide, persulfate or sodium periodate; and then adding chitosan which is subjected to crosslinking modification by dialdehyde cellulose to carry out grafting reaction. According to the method, the grafting effect can be optimal only through the synergistic cooperation of the carboxyl active site amount and the crosslinking degree of the chitosan, and the urea adsorption capacity and the blood compatibility of the cellulose acetate membrane are remarkably improved.

The application provides a method for preparing inorganic mineral and protein composite materials, which comprises the following steps: injecting a uniformly mixed protein solution and an inorganic mineral solution into a shearing stress loading chamber, adding a dehydrating agent into a dialysis chamber, separating the shearing stress loading chamber and the dialysis chamber by a dialysis membrane, applying a shearing stress of 1-10 Pa, acting for 1-8 days, and reacting at a temperature of 10-50 DEG C; and the molecular weight cut-off range of the dialysis membrane is 3-50 kDa. The obtained composite material has excellent mechanical properties, including high strength and toughness, and exhibits good biocompatibility, can support cell adhesion, proliferation and differentiation, and thus effectively promotes bone tissue regeneration. The composite material prepared by the application has a wide application prospect in the fields of bone repair and other biomedical fields.

This invention discloses a polyethersulfone, its preparation method, and its applications. The polyethersulfone satisfies the following formula: x = A1 / (A1+A2) < 6%; where A1 is the integral area occupied by the weight-average molecular weight of not less than 200,000 g / mol in the GPC spectrum, and A1 is denoted as the high molecular weight peak area; A2 is the integral area occupied by the weight-average molecular weight of less than 200,000 g / mol in the GPC spectrum, and A2 is denoted as the main peak area. The polyethersulfone prepared by this invention exhibits a bimodal molecular weight distribution, with the main peak area accounting for more than 90%. The main peak molecular weight can be controlled, and the weight-average molecular weight is between 60,000 and 180,000 g / mol, which can meet the performance requirements of applications such as hemodialysis membranes.