88 results about "Osmotic pressure" patented technology

The invention relates to the technical field of osmotic pressure testing, and particularly discloses an optimization system for osmotic pressure testing of an ipratropium bromide solution, which comprises a data acquisition module, a data processing module and a data processing module, the data recording module records the operation state data of the conductivity acquisition instrument in the use process, and the operation state of the conductivity acquisition instrument directly affects the accuracy of the conductivity data of the standard solution, so that the operation state of the conductivity acquisition instrument can be analyzed based on the data; the conductivity data can be corrected, so that the data is closer to a true value, the reliability of a quality analysis result of a standard solution is improved, the accuracy of a precision detection result of an osmotic pressure detection instrument and an osmotic pressure detection result of an ipratropium bromide solution is further improved, and the optimization of an osmotic pressure detection method is realized.

The invention discloses an osmotic pressure analysis method and device fusing model optimization and physical inversion and a medium, and the method comprises the steps: calculating correlation coefficients of a specified reservoir water level and osmotic pressure under different time lags based on cross-correlation function analysis, and recognizing a differential nonlinear feature corresponding to the maximum correlation coefficient; aiming at the differentiated nonlinear characteristics of different dam types, constructing a plurality of corresponding diagnosis prediction models in parallel, and establishing a model selection decision rule to select an optimal diagnosis model; according to delay parameters obtained through cross-correlation analysis, a permeability coefficient is reversely deduced through a pore medium heat transfer diffusion theoretical formula; according to the regression slope and the theoretical value attenuation factor of the optimal model, a permeability coefficient is reversely deduced in combination with a correction diffusion equation, credibility evaluation and weighted fusion are performed on the permeability coefficient, and a comprehensive permeability coefficient is calculated; and diagnosing the soil type and the permeability characteristic grade. According to the method, the propagation delay characteristic of reservoir water level change in the pore medium can be accurately quantified, and the inversion precision of the permeability coefficient and the engineering applicability are improved.

This invention relates to the field of biotechnology, specifically disclosing a protective agent composition for long-term preservation of Scutellaria baicalensis exosomes and its preparation method. The protective agent composition comprises an osmotic pressure regulator, a stabilizer, a buffer, and a solvent. By optimizing the ratio of each component, the stability of Scutellaria baicalensis exosomes at low temperatures is significantly improved, extending their active preservation time. This composition is suitable for applications in drug delivery, cosmetics, and disease treatment.

The utility model relates to a kind of hole inside upward hole osmotic pressure gauge burying device, including the filter protection component, expandable fixed component, connection adjusting piece and detachable conveying rod connected in turn.Filter protection component contains double-layer porous sleeve: inner sleeve contains osmotic pressure gauge and fills filter medium, and outer sleeve is filled with support filter material between inner sleeve;Expandable fixed component includes elastic sealing member, reset member and support framework, and framework is provided with wire shaft direction passage and connection structure;One end of connection adjusting piece cooperates framework connection structure, and the other end is provided with transmission cooperation part;Conveying rod one end is provided with matching drive part, and the other end is provided with extension connection structure.The utility model realizes upward hole stable placement by expandable fixed component, double-layer sleeve inverse filtration structure prevents silting up and protects osmotic pressure gauge, and detachable design supports repair and reuse, adapts to deep hole and short-term / long-term monitoring demand, and provides reliable technical means for underground engineering osmotic pressure monitoring.

Provided are an electroporation buffer and an electroporation-based exosome drug loading method, wherein the electroporation buffer is a liquid medium used in a method for loading an exogenous substance into an exosome on the basis of electroporation, and has an osmotic pressure of 50-400 mOsm / kg and a pH value of 2.0-8.3. By means of the cooperation of osmotic pressure and pH value, the electroporation buffer greatly improves the loading efficiency of exogenous substances into exosomes without causing substantial damage to exosomes and nucleic-acid-based exogenous substances or any damage caused thereto is controllable, thereby meeting the requirements for commercial applications. In addition, the electroporation buffer and the drug loading method also have the advantage of being low cost.

An amine-containing water concentration system comprising an apparatus 1, which comprises an osmotic pressure generator 10, and a carbon dioxide introducing unit 21. The osmotic pressure generator inc

The invention discloses a cement material crack microbial remediation effect evaluation method, and belongs to the field of cement material remediation effect performance evaluation, and an adopted remediation effect evaluation device comprises a mechanical evaluation system, an osmotic pressure measurement evaluation system and an internal structure analysis evaluation system; the mechanical evaluation system comprises axial pressurizing equipment and confining pressure equipment; the osmotic pressure measurement and evaluation system comprises a liquid injection pipe, a liquid discharge pipe and a sensor; the liquid source comprises a water source and a calcium source; the internal structure analysis and evaluation system comprises sound wave probes capable of rotating by 360 degrees, and the sound wave probes are arranged at the two ends of the sample. The method aims to avoid the situation that the microbial remediation effect is evaluated only from a single aspect, breaks through the single angle and limitation of a traditional method for identifying real breakthrough pressure, more clearly observes and evaluates the sample crack remediation effect, reveals the growth and development, distribution position and deposition form of microorganisms in cracks, and improves the detection accuracy. And meanwhile, cumbersome and complex operation is avoided, and whole-course real-time continuous monitoring is realized.

This invention belongs to the field of microbial fermentation technology and discloses a method and application for improving the production of staminodesmotic acid (Sclerotium sclerotiorum) based on dynamic osmotic pressure regulation. The method uses *Sclerotium sclerotiorum* as the production strain and employs a synergistic strategy of initial culture medium component optimization, precise osmotic pressure regulation during fermentation, and dynamic feeding to enhance synthesis. Utilizing the dual characteristics of sucrose as a carbon source and osmotic pressure regulator, and the osmotic pressure regulating effect of KCl, the osmotic pressure during fermentation is precisely controlled between 1050-1300 mOsmol / kg. This activates the MAPK-CWI signaling pathway and FKs2 gene expression, directionally promoting staminodesmotic acid synthesis and increasing staminodesmotic acid yield. This invention, by optimizing the initial carbon source and inorganic salt concentration, precisely regulating osmotic pressure during fermentation through feeding, and combining molecular mechanism analysis, achieves a significant increase in staminodesmotic acid yield, reduces industrial production costs, and provides technical support for the large-scale industrial production of staminodesmotic acid.

The application discloses a kind of for promoting walnut incision healing and preparation method and application thereof, it is related to walnut cultivation protection technical field.The healing paste is by elastic film-forming base phase 12-35%, high water absorption / water release humidity particle phase 3-12%, hydrophobic water-blocking microphase 5-22%, rheological and interface control phase 1-8%, osmotic pressure and water activity adjustment phase 5-20% and the rest amount of water and preservative etc.composition according to mass percentage;Film-forming base phase includes aqueous polyurethane-acrylate copolymer emulsion and modified polyvinyl alcohol or polyvinyl alcohol-starch blend, humidity particle phase includes crosslinked sodium carboxymethyl cellulose and crosslinked starch or alginate microparticles, hydrophobic microphase includes beeswax, microcrystalline wax, vegetable oil and rosin resin.By preparing each functional phase in turn and assembling in aqueous system, obtain the healing paste suitable for walnut incision protection under different climatic conditions.

Systems and methods for measuring osmotic pressure are described. In many embodiments, double emulsion droplets can be used as osmotic pressure sensors to measure local osmotic pressure. The double emulsion droplets can measure osmotic pressure in living cells and / or tissues.

The invention relates to the technical field of separation and concentration of biological macromolecules, in particular to a concentration column for biological macromolecular substances, which comprises a chamber filled with a water absorption material layer and a separation membrane arranged at the bottom of the chamber, the water absorbing material can absorb solvent components to generate osmotic pressure difference to drive solvents in a solution and other substances with the particle size smaller than that of the biological macromolecular substances to pass through the separation membrane, and the biological macromolecular substances are intercepted by the separation membrane. The concentration column can realize separation and / or concentration of biological macromolecular substances without depending on external pressure or centrifugal force.

The present invention is a concentration system for obtaining, by separating a solvent from a target solution containing a target component, a concentrated liquid in which the target component is concentrated, the concentration system comprising a plurality of semipermeable membrane modules, and a pressurizing device for increasing the pressure of the target solution. Each of the plurality of semipermeable membrane modules has a semipermeable membrane, and a first chamber and a second chamber partitioned by the semipermeable membrane, wherein a concentration flow path formed by connecting the first chambers of the plurality of semipermeable membrane modules is provided, and a dilution flow path formed by connecting the second chambers of the plurality of semipermeable membrane modules is provided. The target solution is caused to flow through the concentration flow path, and an auxiliary solution having osmotic pressure is caused to flow through the dilution flow path. The concentration system comprises at least one selected from a group consisting of a concentrated liquid measuring device and an auxiliary solution measuring device, and an adjusting device. The adjusting device includes at least one selected from a group consisting of a concentrated liquid adjusting device and an auxiliary solution adjusting device. The concentrated liquid measuring device is provided downstream of the concentration flow path, and the auxiliary solution measuring device is provided downstream of the dilution flow path. The concentrated liquid measuring device measures at least one selected from a group consisting of the flow rate and the concentration of the concentrated liquid. The auxiliary solution measuring device measures at least one selected from a group consisting of the flow rate and the concentration of the auxiliary solution. The concentrated liquid adjusting device controls the pressurizing device such that a measured value of the concentrated liquid measuring device falls within a predetermined range. The auxiliary solution adjusting device controls the pressurizing device such that a measured value of the auxiliary solution measuring device falls within a predetermined range.

The invention provides a TBM tunneling grouting parameter intelligent regulation and control system and method based on seepage pressure dynamic inversion, and belongs to the technical field of tunnel engineering intelligent construction. Aiming at the problems of pipe blockage, slurry waste and support failure caused by mismatching of grouting parameters and hydrogeological conditions in deeply-buried water-rich stratum TBM construction, an integrated technical scheme of seepage pressure inversion, intelligent decision-making, real-time regulation and control and closed-loop correction is provided. The system comprises a seepage pressure field inversion module, a multi-parameter fusion detection module, an intelligent decision regulation and control module, a dynamic execution and feedback module and a closed-loop correction module. According to the method, a surrounding rock seepage pressure field is inversed in real time based on a distributed optical fiber sensing network, a grouting efficiency coefficient model is constructed to evaluate the slurry diffusion radius, cooperative regulation and control parameters are generated by adopting an XGBoost multi-objective optimization algorithm, and the model is continuously corrected through closed-loop feedback. The grouting material utilization rate can be increased, the pipe blocking rate is reduced, the supporting effect is guaranteed, and reliable technical support is provided for complex geology TBM tunneling.

The invention relates to the technical field of fresh food fresh-keeping control, and discloses a fresh food fresh-keeping control system based on osmotic pressure cooperating with a low-temperature barrier, and the system comprises a category parameter locking module which is used for obtaining and fixing the category parameters of the current batch of fresh food; the first measurement conversion evaluation module is used for collecting environment temperature and humidity and calculating environment water activity and effective osmotic pressure difference; the priority path judgment module is used for determining a priority regulation and control path according to the inhibition degree gap symbol and the cold damage temperature window upper limit; the main variable correction module is used for adjusting the temperature and the humidity according to the priority path and rechecking the inhibition degree and the osmotic pressure difference; the sub-variable fine adjustment module is used for finely adjusting sub-variables according to the category parameters and rechecking the inhibition degree and the osmotic pressure difference; the inspection amplitude limiting module is used for re-checking the osmotic pressure difference and adjusting the temperature and humidity; and the disturbance switching checking module is used for returning to the first measurement conversion evaluation module during disturbance and checking batch parameters. According to the invention, accurate fresh-keeping control of fresh food in the low-temperature storage process is realized, the fresh-keeping period is prolonged, and the quality is kept stable.

The utility model relates to the technical field of osmotic pressure monitoring, in particular to an osmotic pressure monitoring device. The embodiment of the utility model provides an osmotic pressure monitoring device. The osmotic pressure monitoring device comprises a protection tube, a protection unit and an osmometer, the protection pipe is provided with a protection cavity and a first water inlet hole communicated with the protection cavity, the protection unit is installed in the protection cavity, the protection unit comprises a driving assembly and a protection cover which are connected, and the protection cover is provided with a plurality of second water inlet holes communicated with the protection cavity; the osmometer is installed in the protection cavity and provided with a pressure measuring hole, and the pressure measuring hole is located in the protection cover. Under the condition that water enters the first water inlet holes, the driving assembly can drive the protective cover to extend out of the protective pipe under the action of water pressure, so that the multiple second water inlet holes are exposed out of the protective pipe. According to the osmotic pressure monitoring device provided by the invention, when the osmotic pressure monitoring device is lowered from the earth surface to the deep underground water, under the isolation of the protection pipe, shallow sand and mud can be effectively prevented from entering the protection cover to influence the detection of the osmometer.

The utility model discloses a kind of detection underground water level and osmotic pressure and settlement monitoring device, belong to the technical field of underground water monitoring equipment, including a kind of detection underground water level and osmotic pressure and settlement monitoring device, including large-diameter osmotic tube, small-diameter osmotic tube and protection device;The protection device is upper opening hollow shell, the large-diameter osmotic tube is communicated with small-diameter osmotic tube and is respectively fixed in the inside of protection device;The side end face of large-diameter osmotic tube far from small-diameter osmotic tube is fixedly connected with osmotic detection meter.This utility model device is not influenced by soil settlement objectively as a whole, settlement plate does not occur horizontal deviation, influence actual settlement depth monitoring.Effective solution can be made to the problem that the change of embedding elevation of osmotic pressure gauge caused by foundation settlement leads to inaccurate measurement value, soil deformation leads to cable breakage, damaged osmotic pressure gauge can also be replaced at any time.

This invention discloses a method for transporting *Pterygodon spp.* for benthic bioremediation, including pre-transportation pretreatment, low-temperature transportation, and post-transportation adaptation and domestication. Before transportation, by withholding feed and stimulating the expulsion of mud and sand by low osmotic pressure, the *Pterygodon spp.* effectively induces the *Pterygodon spp.* to contract its body segments, actively expel mud and sand to clean its intestines, and achieve intestinal and body surface purification, avoiding mechanical damage and water quality deterioration risks caused by mud and sand residue in the body during transportation. After transportation, adaptation and domestication can significantly reduce the *Pterygodon spp.*'s transportation stress response, reduce body segment damage caused by violent twisting, and induce the *Pterygodon spp.* to burrow naturally by creating a suitable substrate environment and tidal environment, quickly restoring its burrowing and benthic lifestyle.

The present invention provides a fat-dissolving composition and a use thereof. The fat-dissolving composition of the present invention comprises a pharmaceutically active ingredient, an inclusion material, a pH regulator optionally selected from one or more of a buffer, a stabilizer, an osmotic pressure regulator, and a complexing agent, and optionally purified water, wherein the pharmaceutically active ingredient is selected from one or more of deoxycholic acid, a pharmaceutically acceptable salt of deoxycholic acid, and a deoxycholic acid derivative, and the amount of the inclusion material ranges from 4% to 35% on the basis of the total weight of the fat-dissolving composition. Compared with conventional formulations at the same dose, the fat-dissolving composition of the present invention can significantly reduce adverse effects at the administration site while having a good fat-dissolving effect, and has higher safety.

The invention provides a fat-dissolving composition and application thereof. The fat-dissolving composition comprises an active pharmaceutical ingredient, an inclusion material, a pH regulator, one or more optional components selected from a buffering agent, a stabilizing agent, an osmotic pressure regulator and a complexing agent, and optional purified water, the active pharmaceutical ingredient is selected from one or more of deoxycholic acid, pharmaceutically acceptable salts of deoxycholic acid and deoxycholic acid derivatives, and the dosage range of the inclusion material is 4-35% based on the total weight of the fat-dissolving composition. Compared with a conventional preparation with the same dosage, the fat-dissolving composition disclosed by the invention has the advantages that under the condition that a good fat-dissolving effect is achieved, the adverse reaction of an administration part can be obviously relieved, and the fat-dissolving composition has higher safety.

The invention provides a fusion method of pore protein and a membrane, a pore protein jack buffer solution and application. The fusion method comprises the following steps: distributing a first solution on the first side of the membrane, and distributing a second solution on the second side of the membrane; applying voltage to two sides of the membrane, fusing the pore protein and the membrane, and detecting current in the solution; when the current is increased, the pore protein is inserted into the membrane, the voltage is adjusted to 0V, and the fusion of the pore protein and the membrane is completed; the first solution comprises a first buffer solution containing pore protein, and the second solution comprises a second buffer solution without pore protein; the osmotic pressure of the first solution is greater than that of the second solution. The porous protein and membrane fusion single porosity problem in the prior art can be solved, and the method is suitable for the field of biological analysis and detection.

The application discloses a PIP-seq technology-based adjustable osmotic pressure single-cell sequencing kit and a detection method, and through a wrapping buffer with adjustable osmotic pressure and a non-toxic digestion system, high-throughput sequencing of marine high-osmotic living cells and freshwater low-osmotic living cells without chemical fixation is realized for the first time, and the retention rate of sensitive cell groups (such as stinging cells and freshwater ion-regulating cells) is doubled. By only changing the buffer formula, marine and freshwater samples can be seamlessly switched without changing the core reaction process, and the kit has strong versatility, and successfully solves the osmotic pressure barrier problem that has long plagued the field of aquatic biology.

The application discloses a lipoic acid injection composition applied to mesoderm and a preparation method thereof, wherein the lipoic acid injection composition comprises lipoic acid, cyclodextrin, a stabilizer, a regulator, a pH regulator and an osmotic pressure regulator. The lipoic acid powder is dissolved by using the cyclodextrin, the solubility of the lipoic acid is improved, the post-stability of the injection is improved by using the wrapping property of the cyclodextrin, meanwhile, the irritation of the cyclodextrin to the mesoderm is reduced by adding hyaluronic acid and a salt thereof, and the comfortable feeling of a user is obviously improved.

The invention relates to the technical field of rock mechanics engineering, and discloses a true triaxial electromagnetic loading-based osmotic pressure and temperature coupling simulation device and method.The true triaxial electromagnetic loading-based osmotic pressure and temperature coupling simulation device comprises a triaxial electromagnetic loading assembly, a test box, six dynamic sealing assemblies, an osmotic pressure assembly, a heating assembly and an acquisition assembly, the six surface openings are matched with the waveguide rod; the six groups of dynamic sealing assemblies seal gaps between the openings and the waveguide rod to form a sealed cavity; the osmotic pressure assembly is communicated with the sealed cavity, the heating assembly is arranged in the test box, and the acquisition assembly acquires experimental data; according to the structure, three-axis six-direction synchronous dynamic loading can be realized, the osmotic pressure and the temperature in the sealed cavity can be synchronously and accurately regulated and controlled in dynamic loading, and the problem that a traditional device only performs single-axis dynamic loading and cannot cooperatively simulate a multi-field coupling environment is solved; and the occurrence environment of high ground stress, high ground temperature and high osmotic pressure of deep rock mass and multi-axis and multi-direction power disturbance coupling is truly restored.

The present invention comprises a semipermeable membrane and a basic solution 10 and a membrane-forming solution 11 separated by the semipermeable membrane. The semipermeable membrane is provided with, in a continuous manner, at least two kinds of inorganic membranes 21, 22 having different formation rates, the inorganic members being formed by self-assembly through contact between the basic solution and the membrane-forming solution. With the osmotic pressure difference across the semipermeable membrane as the driving force, the membrane-forming solution 11 is injected into the basic solution 10, accompanied by localized damage to the semipermeable membrane, and the semipermeable membrane is reformed at the damaged location.

The application discloses a kind of different effective stress state under fault zone seepage characteristic in-situ test device and method, comprising: water supply system, osmotic pressure control system, field in-situ sample, data measurement system and permeate collection system;The field in-situ sample is connected with water supply system, osmotic pressure control system, data measurement system, permeate collection system respectively;The application realizes the double regulation of sample pore water pressure, osmotic pressure by osmotic pressure control system, to obtain the coupling constitutive relation between the permeability coefficient-effective stress in fault zone, the critical hydraulic gradient and the failure hydraulic gradient under a certain effective stress state determined according to the specific circumstances of project.

The invention discloses a mounting method of an osmotic pressure monitoring device, which comprises the following steps of: drilling to form a logging well, and mounting a piezometric tube into the logging well; the osmometer is inspected, and the osmometer is installed in the pressure measuring pipe; if the osmometer is qualified, a protection device is arranged at the top of the piezometer tube. The method is based on an osmotic pressure monitoring device, the osmotic pressure monitoring device comprises a pressure measuring pipe, an osmometer is arranged in the pressure measuring pipe, and a protection device is arranged at the top of the pressure measuring pipe. Through the concrete base, the protection device can be fixed on a soil base and a batholith. Meanwhile, through the arrangement of the cushion layer and the multiple outer layers, the extrusion force formed on the piezometric tube is effectively reduced, and the durability of the piezometric tube is improved. The device is convenient to set and can be prepared from common materials in construction, and the cost can be effectively reduced.

To provide an absorbent article excellent in rewetting resistance.SOLUTION: The absorbent article 1 for absorbing blood comprises an absorbent body 9 having an absorbent core 11 and a liquid-permeable sheet 3 arranged on the skin side of the absorbent body 9, wherein the liquid-permeable sheet 3 contains a blood lubricity imparting agent 31 for transferring the blood to the absorbent body 9. The absorbent article 1 includes an osmotic pressure adjusting agent 33 for adjusting the osmotic pressure of the blood cell component in the blood, and the absorbent core 11 includes a superabsorbent polymer and a hydrophilic fiber so that the ratio of the superabsorbent polymer to the hydrophilic fiber is 5 mass% or more.SELECTED DRAWING: Figure 2

The invention discloses a colloid osmotic pressure tester and an application method thereof, and belongs to the technical field of osmotic pressure determination. The measurement record comprises an osmotic pressure measurement value and a measurement moment when the osmotic pressure measurement instrument measures the osmotic pressure measurement value; performing interpolation processing on the measurement records to obtain a plurality of groups of osmotic pressure measurement values and measurement moments of the osmotic pressure measurement values measured by an osmotic pressure measurement instrument; and predicting the osmotic pressure value according to the plurality of sets of osmotic pressure measurement values and the measurement time when the osmotic pressure measurement instrument measures the osmotic pressure measurement values. According to the method, the osmotic pressure measurement predicted values of the next time or multiple times in the future are obtained through the osmotic pressure value measurement function, the prevention effect is achieved, and meanwhile the osmotic pressure measurement predicted values of the next time or multiple times in the future are more accurate and reliable.

The application discloses a cement soil indoor maintenance and permeability coefficient testing device and method considering groundwater seepage action, and the device comprises a cement soil maintenance and permeability coefficient testing mechanism. The device provides a pressure source for the pressure tank through an air compressor, adjusts the size of the osmotic pressure through a data control acquisition system in combination with the groundwater conditions of a construction site, provides a suitable hydraulic gradient for the flow of water in the cement soil sample, collects the exudate through an exudate metering pipe, and records the exudate through the data control acquisition system. According to the Darcy permeation law, the permeability coefficient of the cement soil sample is tested, and the change rule of the cement soil permeability coefficient under the seepage action is intuitively reflected. After the cement soil sample reaches a predetermined maintenance age, the unconfined compressive strength test is carried out to evaluate the strength characteristics.