The invention belongs to the technical field of radioactive particle implantation, and discloses a method for realizing radioactive particle implantation by using laser guidance, comprising the following steps: S1, marking a target area on the body surface of a patient; S2, obtaining the image examination data of the patient target area and introducing the image examination data into the processing system to generate a disease body model; 3, introducing the disease body model into a computer three-dimensional treatment plan system for dimension development, determining and adding a source lineof a puncture needle path, arranging radioactive particles on the source line, and derive the radioactive particles in the form of a three-dimensional data packet; S4, introducing the three-dimensional data packet into the orbit equipment and emitting laser rays according to the three-dimensional coordinate vector of the distribution source line; and 5, inserting a particle needle along that laser ray and implant radioactive particles. The invention adopts laser technology to guide, combines the advantages of freehand puncture and template puncture, shortens the preparation period before operating, lowers the cost, and can change the implantation scheme in time according to the change of the tumor in the patient body, and has strong flexibility.