1197 results about "Buffering agent" patented technology

The invention is about a method of marking ink which is only used to defend fake. The composition of it is: lipidol or lipid, surface active agent, integration agent, water, buffering agent. Their mass percents are: 1,2-hexylene glycol: 5%-15%, butanol: 1-5%, DH-1: 5-10%, EDTA: 0.1-0.5%, MS-1: 0.1-1%, water: the rest. The process is: a. dissolving the colorant in water, b. put the correct percent of 1,2-hexylene glycol and butanol into the solvent, then dropping the MS-1 and EDTA solution when mixing the solvent for 30-50 min, c. put the rest precent of water into the printing ink box. The picture and word would be shown red fluorescence in the UV but blank in the usual light.

The invention discloses an efficient wet desulfurization synergist and a preparation method thereof, and relates to the technical field of flue gas desulfurization. The efficient wet desulphurization synergist comprises the following raw materials in parts by weight: 10-20 parts of sodium formate, 5-10 parts of citric acid, 20-30 parts of binary acid, 5-6 parts of a surfactant, 15-20 parts of magnesium salt, 12-18 parts of sodium salt and 2-5 parts of a pH buffer agent. The preparation method comprises the following steps: reacting cyanuric chloride with lauryl amine to generate a monosubstituted compound; then reacting with L-asparaginic acid to generate a disubstituted compound; reacting with diethylenetriamine to generate a bis-triazine ring compound; and finally, reacting with sodium 2-chloroethanesulfonate to generate the surfactant. The high-efficiency wet desulphurization synergist prepared by the invention has a desulphurization effect.

The invention relates to a fluorine-containing binder for a sulfide all-solid-state battery and a preparation method and application thereof.The binder is formed by copolymerizing isoprene and lithium perfluorovinyl ether sulfonate, specifically, the lithium perfluorovinyl ether sulfonate, a chelating agent, an emulsifying agent, ferrous sulfate, a reducing agent and an acid-base buffering agent are dissolved in water, cooling is conducted in the inert atmosphere, and the fluorine-containing binder for the sulfide all-solid-state battery is obtained. And adding isoprene, an initiator and a molecular weight regulator, and carrying out polymerization reaction to obtain the fluorine-containing binder. The isoprene can enhance the solubility of the lithium perfluorovinyl ether sulfonate fragment in the non-polar solvent, so that the whole polymer is dissolved in the non-polar solvent; the perfluorovinyl ether lithium sulfonate has a large space proportion of fluorocarbon groups, and has a shielding effect on hydrocarbon groups on isoprene, so that the stability of the whole polymer can be improved. The fluorine-containing binder prepared by the preparation method disclosed by the invention is a binder with high elasticity, high ionic conductivity and high stability.

The present disclosure provides agronomically stable liquid agricultural compositions, methods of formulation thereof, and methods of application thereof. The agricultural compositions comprise nitrogen-fixing microorganisms and one or more of a buffering agent, a microbial stabilizer, and a physical stabilizer. The disclosed liquid agricultural compositions have a longer shelf life and greater ease of application than other existing dry and liquid formulations. The disclosed liquid agricultural compositions are stable for a period of thirty days or longer with low toxin accumulation and high microbial stability. The compositions are suitable for use on agricultural plant tissues or the environs thereof for providing a source of fixed atmospheric nitrogen to the agricultural plant. The compositions are used to increase crop yield and decrease yield variance.

The invention discloses a pharmaceutical composition for promoting aTreg cell differentiation and application thereof, and relates to the field of biological medicine, and the pharmaceutical composition comprises zinc salt, a basic cell culture medium, fetal calf serum, antibiotic, L-glutamine and a pH buffer agent. According to the application, the basic cell culture medium is used for providing basic nutrition required by cell growth for lymphocytes, the fetal calf serum is used for providing growth factors, hormones, adhesion proteins and nutrient substances required by cell growth for the lymphocytes, and the antibiotics are used for preventing bacterial infection; l-glutamine provides key amino acid for cell energy metabolism and participates in synthesis of protein and nucleic acid, zinc salt provides zinc ions, and under the comprehensive action, the proportion of Treg cells and aTreg cells differentiated from lymphocytes in peripheral blood mononuclear cells is increased.

S-Beta-hydroxybutyric acid compositions for oral delivery are effective in rapidly raising blood ketone levels without causing acute acidosis or gastrointestinal (GI) distress when consumed in sufficiently dilute form and / or as a gel or suspension. By limiting added beta-hydroxybutyrate salts containing alkali or alkaline earth metal ions, beta-hydroxybutyric acid solutions, gels, or suspensions can deliver exogenous ketone bodies without significantly altering electrolyte balance. Although aqueous beta-hydroxybutyric acid solutions are moderately acidic with a pH of about 3.5 to 4, when diluted with sufficient water, the water acts as a pseudo buffering agent that offsets otherwise harsh acidic effects when consumed orally. Gels and suspensions can also ameliorate acidic effects by partially encapsulating the beta-hydroxybutyric acid. Beta-hydroxybutyric acid can be pure S-beta-hydroxybutyric acid or a non-racemic mixture enriched with S-beta-hydroxybutyric acid relative to R-beta-hydroxybutyric acid.

The invention discloses positive electrode slurry for preventing formation of gel and a preparation method of the positive electrode slurry. The method comprises the following steps: S1, drying a positive electrode active material under the protection of inert gas; s2, carrying out surface modification by using a functionalized silane coupling agent; s3, drying the conductive agent under a high-temperature vacuum condition; s4, under the protection of inert gas, lithium alkyl sulfonate, a polyhydric alcohol chelating agent and polyvinylidene fluoride are subjected to a reaction to prepare a modified binder; s5, mixing and dispersing the modified active material, the conductive agent, the modified binder and the acidic buffer agent in a low-dew-point drying chamber; s6, performing ultrasonic treatment on the slurry under a vacuum condition; and S7, adding a cross-linked fluorosilane coupling agent, mixing at a low speed and precisely filtering to obtain the anti-gel positive electrode slurry. According to the invention, through a multi-synergistic anti-gel mechanism, the problem that the positive electrode material slurry is easy to form gel is solved, and the prepared slurry has excellent stability, rheological property and coating performance, so that the electrochemical performance of the battery is improved.

The invention provides a copper-nickel alloy foil and a preparation method and application thereof, and belongs to the technical field of lithium ion battery negative electrode current collectors, and the preparation method comprises the following steps: preparing a copper-nickel composite electrolyte, and adding a coordination agent, a pH buffer agent and an additive into the copper-nickel composite electrolyte to obtain a mixed electrolyte; the coordination agent comprises a main coordination agent and an auxiliary coordination agent, and the main coordination agent comprises at least one of trisodium citrate, potassium sodium tartrate and sodium pyrophosphate; the auxiliary coordination agent comprises at least one of ammonia water, glycine and triethanolamine; and a cathode and an anode are placed in the mixed electrolyte, the pH of the mixed electrolyte is controlled to be 6-10, direct current is applied for electrochemical deposition, and the copper-nickel alloy foil is obtained. According to the method, the alkalescence system is adopted, the main coordination agent and the auxiliary coordination agent are used, full coordination of free Cu < 2 + > and Ni < 2 + > is achieved, precipitation is avoided, the hydrogen evolution phenomenon is greatly reduced, and the alloy foil quality is improved.

The invention discloses a preparation method of a vitamin C liposome preparation capable of improving encapsulation efficiency, the vitamin C liposome preparation is prepared by an ethanol injection-high pressure microjet circulation homogenization method, the homogenized liposome is small in particle size and uniform in distribution, and meanwhile, by combining a dialysis purification and buffer agent pH regulation process, the encapsulation efficiency of the vitamin C liposome preparation is improved. The prepared vitamin C liposome preparation can still keep high stability under the condition that cholesterol is not contained, and the problem that in the prior art, a vitamin C liposome preparation is low in encapsulation efficiency is effectively solved.

The invention relates to the technical field of glass cleaning agents, in particular to an environment-friendly cover plate glass cleaning agent and a preparation method thereof. The environment-friendly cover plate glass cleaning agent comprises the following raw materials in percentage by weight: 12-20% of inorganic base, 8-12% of a surfactant, 5-8% of a chelating agent, 3-5% of a humectant, 1-3% of an adsorbent, 1-3% of a dispersing agent, 0.3-1% of a buffering agent and the balance of deionized water, the surfactant is dodecyl glucoside and dodecyl ethyoxyl sulphobetaine, and the weight range ratio of the dodecyl glucoside to the dodecyl ethyoxyl sulphobetaine is (3-1): 1; the chelating agent is one or more of sodium gluconate, sodium polyaspartate and sodium polyepoxysuccinate. According to the present invention, the degradable surfactant and the degradable chelating agent are adopted, and the dispersant is added to modify the nanometer titanium dioxide, such that the low pollution property is achieved while the high decontamination efficiency and the anti-fingerprint ability are considered.

The present invention relates to a highly concentrated, stable pharmaceutical formulation of a pharmaceutically active anti-HER2 antibody, such as e.g. Trastuzumab (HERCEPTIN™), Pertuzumab or T-DM1, or a mixture of such antibody molecules for subcutaneous injection. In particular, the present invention relates to formulations comprising, in addition to a suitable amount of the anti-HER2 antibody, an effective amount of at least one hyaluronidase enzyme as a combined formulation or for use in form of a co-formulation. The formulations comprise additionally at least one buffering agent, such as e.g. a histidine buffer, a stabilizer or a mixture of two or more stabilizers (e.g. a saccharide, such as e.g. α,α-trehalose dihydrate or sucrose, and optionally methionine as a second stabilizer), a nonionic surfactant and an effective amount of at least one hyaluronidase enzyme. Methods for preparing such formulations and their uses thereof are also provided.

The invention relates to the technical field of nutrient element extraction, and discloses a step-by-step extraction method of organic selenium in natural selenium-rich agricultural products, which comprises the following steps: cleaning, drying and crushing the natural selenium-rich agricultural products into fine powder; then sequentially using an aqueous solution containing a buffer agent, low-concentration ethanol and a high-concentration organic solvent for ultrasonic-assisted extraction to respectively obtain water-soluble, hydrophilic, hydrophobic and fat-soluble organic selenium compounds; and finally, combining the extracting solutions in the steps, and carrying out rotary evaporation concentration and purification treatment to obtain the high-purity organic selenium compound. Through a step-by-step extraction method, different types of organic selenium compounds in natural selenium-rich agricultural products are efficiently extracted by using the aqueous solution, the low-concentration ethanol and the high-concentration organic solvent respectively under low-temperature and mild conditions, so that high purity and biological activity are kept, meanwhile, the process flow is simplified, and the production cost is reduced. The energy consumption and the use of organic solvents are reduced, the environmental pollution is reduced, and the method is suitable for large-scale industrial production.

The invention belongs to the technical field of biomedicine, and particularly relates to a paris polyphylla exosome, a preparation method thereof and application of the paris polyphylla exosome in treatment of psoriasis, in the method, fresh paris polyphylla rhizomes are cleaned and washed with a buffering agent, the washed paris polyphylla rhizomes and the buffering agent are mixed according to the mass ratio of 1: (1.5-2.5), after mixing, crushing and filtering are conducted, and the paris polyphylla exosome is obtained; the preparation method comprises the following steps: extracting paris polyphylla from paris polyphylla to obtain a paris polyphylla crude extract for later use, carrying out differential centrifugation on the paris polyphylla crude extract, taking supernate and concentrating to obtain an exosome crude extract, sequentially adding the exosome crude extract into cane sugar with the concentration of 15%, 30%, 45% and 60%, and carrying out cane sugar gradient purification to obtain the paris polyphylla exosome. The paris polyphylla exosome is in the shape of a cup-shaped circle and has a complete double-layer membrane structure, the protein concentration is 3.5-4.5 ug / ml, the particle size is 100-200 nm, and the paris polyphylla exosome is beneficial to improvement of psoriasis, is good in curative effect and fast in effect taking, and has high economical efficiency and safety.

The invention relates to the technical field of OLED (Organic Light Emitting Diode) manufacturing process etching processes, in particular to a silver etching solution for an OLED manufacturing process as well as a preparation method and application of the silver etching solution. The silver etching liquid comprises nitric acid, phosphoric acid, a buffer agent, a metal ion chelating agent and an ionic liquid inhibitor, the ionic liquid inhibitor comprises 1-butyl-3-methylimidazole phosphate, the metal ion chelating agent is selected from at least one of pyromellitic acid, diethylenetriamine pentaacetic acid and ethylenediamine tetramethylene phosphoric acid, and the buffer agent is selected from at least one of sodium chloride, sodium chloride and sodium chloride. The buffering agent comprises acetic acid, and all the components are prepared according to a specific mass ratio. The etching solution can balance the etching rate of silver and indium tin oxide, avoid silver residues and black spot defects, prolong the service life of the solution, reduce the use of a volatile buffer agent, adapt to the OLED fine manufacturing process, improve the product yield and reduce the production cost, and is suitable for etching of a metal substrate in the OLED manufacturing process.

A liquid pharmaceutical formulation comprising a CNP compound, a buffering agent, an isotonicity agent, a preservative and optionally an antioxidant and methods for making and using such formulation.

The present invention relates to an ophthalmic preparation. The ophthalmic preparation comprises: penehyclidine hydrochloride, phosphate buffer, sodium chloride and hypromellose; wherein, based on the total volume of the ophthalmic preparation, the concentration of the phosphate buffer is not higher than 25 mM and not 0 mM, the mass-volume ratio of penehyclidine hydrochloride is 0.01% - 2%, and the mass ratio of penehyclidine hydrochloride to sodium chloride is (0.011 - 0.85):1. The ophthalmic preparation of the present invention has the advantages of low irritation and high stability.

The utility model discloses a medicine fermentation device for biosynthesis, which is characterized in that a stirring shaft is of a hollow pipe structure, a stirring blade is of a jacket structure communicated with the inside of the stirring shaft, and a plurality of exhaust gaps are formed in the stirring blade; a rotary sealing joint is arranged at the lower end of the stirring shaft and is hermetically communicated with an air pump through an air guide pipe; wherein liquid stored in the buffering agent storage box and liquid stored in the weak base storage box are fed into the tank body through a micropump and a guide pipe respectively. According to the utility model, aeration and the stirrer are integrated together, specifically, the air pump is used for providing air for the stirring shaft, the stirring motor is used for driving the stirring shaft to rotate at the same time, and in the process that the stirring shaft drives the stirring blades to rotate, the air in the stirring blades is dispersed into the fermentation liquid through the exhaust gaps; through the hidden design of the aeration structure, the complexity of the aeration equipment is reduced, and subsequent cleaning is facilitated.

The invention discloses a preparation method and application of a rare earth element doped ruthenium oxide catalyst, and the preparation method comprises the following steps: (1) dissolving a rare earth metal salt, a ruthenium metal salt, dopamine hydrochloride and a Tris-HCl buffer agent in water to obtain a mixed solution, and carrying out in-situ polymerization reaction, solid-liquid separation and drying to obtain a powder precursor; and (2) carrying out high-temperature calcination on the powder precursor obtained in the step (1) to obtain the rare earth doped ruthenium oxide catalyst. Rare earth metal salt and ruthenium salt precursors are dispersed on an in-situ constructed porous carbon substrate, and the rare earth element doped ruthenium oxide nanosheet is generated by oxidation under a high-temperature condition through a self-sacrifice template method. The method has the characteristics of high efficiency and no pollution. The rare earth element doped ruthenium oxide disclosed by the invention is used as a catalyst for the anodic reaction of the acidic electrolyzed water, and shows excellent catalytic activity and wide application prospect.

The present disclosure describes low pH formulations comprising. e.g., an antigen-binding protein that binds CD3, at least one buffer agent, at least one saccharide and at least one surfactant.

The invention relates to the technical field of coatings, in particular to a high-performance styrene-acrylic emulsion, a preparation method thereof and application of the high-performance styrene-acrylic emulsion in coatings. The preparation method of the styrene-acrylic emulsion comprises the following steps: adding a surfactant, a buffer agent, 2-ethylhexyl acrylate, n-butyl acrylate, styrene, ethylene glycol dimethacrylate and monomer acrylic acid into a first part of water, and uniformly dispersing to obtain a prefabricated emulsion; heating the first part of the prefabricated emulsion, adding the first part of the initiator solution, and keeping the temperature; adding a second part of the prefabricated emulsion and a second part of the initiator solution, and heating and preserving heat after the addition is finished; and cooling the system, adding a third part of the initiator solution, continuously keeping the temperature, then cooling, and regulating the pH value of the system by using a second neutralizer, thereby obtaining the product. The styrene-acrylic emulsion is used as a component of the water-based heat insulation and heat preservation coating and can absorb more hollow microspheres and SiO2 aerogel cement in the coating, so that the coating has higher heat insulation and heat preservation performance, and the coating also has higher mechanical performance.

The invention relates to the technical field of corrosion prevention of oil field pipes, and particularly discloses electroplating liquid for a high-tungsten-content hydrogen sulfide corrosion resistant sleeve coating and a preparation process of the electroplating liquid. The invention discloses electroplating liquid for a high-tungsten-content hydrogen sulfide corrosion-resistant sleeve coating. The electroplating liquid comprises the following raw materials: 60-90 parts of a composite tungsten source; 40-70 parts of a nickel-cobalt main salt; 35-55 parts of a composite complexing agent; 1-5 parts of carboxylated graphene quantum dots; 1 to 5 parts of an aminated ZIF-8 derived carbon nanocage; 1-5 parts of a rare earth stabilizer; 1-4 parts of sodium hypophosphite; 1-4 parts of sodium citrate; 1-3 parts of a surfactant; 15 to 25 parts of a buffering agent; and 350 to 450 parts of deionized water. According to the single-layer electroplated layer, the interface stress of the multi-layer structure can be eliminated, so that other interface problems such as plating layer cracking caused by underground temperature fluctuation are avoided, it is guaranteed that the thickness of the plating layer reaches the standard, and then it is guaranteed that the plating layer has excellent corrosion resistance.

Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.

The present disclosure provides agronomically stable liquid agricultural compositions, methods of formulation thereof, and methods of application thereof. The agricultural compositions comprise nitrogen-fixing microorganisms and one or more of a buffering agent, a microbial stabilizer, and a physical stabilizer. The disclosed liquid agricultural compositions have a longer shelf life and greater ease of application than other existing dry and liquid formulations. The disclosed liquid agricultural compositions are stable for a period of thirty days or longer with low toxin accumulation and high microbial stability. The compositions are suitable for use on agricultural plant tissues or the environs thereof for providing a source of fixed atmospheric nitrogen to the agricultural plant. The compositions are used to increase crop yield and decrease yield variance.

The invention discloses a preparation method of a quinoa-fruit compound beverage, and belongs to the technical field of beverage processing. Comprising the following steps: S1, raw material pretreatment (in the quinoa pretreatment, high-viscosity enzymolysis modified quinoa pulp is prepared through double-enzyme synergistic hydrolysis of acid protease and natural kiwi fruit protease in kiwi fruit juice in combination with gradient heating and grinding; the preparation method comprises the following steps: pretreating raspberries, namely preparing suspended raspberry seed pulp by freeze-drying, superfine grinding and coating with enzymolysis modified quinoa pulp, and meanwhile, adding tea polyphenol, glycerol and a compound buffer agent to prepare color-protecting anti-crosslinking raspberry juice), S2, blending and homogenizing, and S3, sterilizing and filling. Through three stages of raw material pretreatment, blending and homogenization, and sterilization and filling, the nutritional conflict problems mentioned in the background technology, such as quinoa protein acid denaturation and aggregation, quinoa PPO-mediated raspberry anthocyanin oxidation browning, raspberry seed retention and suspension stability, and taste adaptation, are solved.

The invention discloses silicon polyurethane modified acrylic emulsion foaming printing adhesive cement and a preparation method thereof. The foaming printing adhesive cement is prepared from deionized water, a defoaming agent, an emulsifying agent, a buffering agent, an initiator, silicon PU modified acrylic emulsion, butyl acrylate, methyl methacrylate, itaconic acid, hydroxyethyl acrylate, a functional monomer, styrene, silane, a preservative and the like. The milk white liquid with blue fluorescence is prepared through a pre-emulsification technology, the viscosity is 300-600 mPa.s, the solid content is 47%-51%, a film forming matter is colorless and transparent, the pH is 7-8, the emulsion has the advantages of being high in adhesive force, good in water resistance and good in toughness, the preparation method is convenient to operate, water serves as a dispersion medium, harm to human bodies and the environment is avoided, and the production environment is safe. Foaming printing adhesive cement obtained from a physical foaming agent, titanium dioxide and the like prepared from the emulsion has a relief type three-dimensional ink pattern and a high-saturation color effect.

The invention belongs to the technical field of contact lens care, and provides temperature-sensitive contact lens eye-moistening gel and a preparation method thereof. The temperature-sensitive contact lens eye-moistening gel is prepared from the following raw materials in parts by mass: a gel matrix, a surfactant, an osmotic pressure regulator, an active component, a chelating agent, a buffering agent and the balance of injection water, the composition of the gel matrix is defined. Chitosan, sodium hyaluronate and polyvinyl alcohol are compounded to serve as a gel matrix, a polyelectrolyte compound is formed, gelation time is shortened, gel strength and swelling resistance are improved, biocompatibility is improved, and drug-loaded delivery of active ingredients is achieved; the gel matrix and the surfactant are reasonably selected, the viscosity of the solution is increased, the gelation time is shortened, the excellent effect of relieving eye fatigue and dryness is achieved, the wearing comfort of the contact lens is remarkably improved, and the oxygen permeation effect of the contact lens is not obviously reduced after gel forming.

The invention discloses an insulating nano ceramic resin composite coating. The preparation method comprises the following steps: 1, mixing methyl methacrylate and butyl acrylate, and dropwise adding the mixture into an aqueous solution containing an emulsifier, an initiator and a buffer agent under a protective atmosphere for reaction to obtain a seed emulsion; and 2, emulsifying the modified filler, methyl methacrylate, butyl acrylate, an emulsifier and water, adjusting the pH value, and dropwise adding into the seed emulsion and the initiator under a protective atmosphere to react. And then cooling and adding a redox initiation system for continuous reaction to finally obtain the composite coating. The preparation method has the beneficial effects that the hexagonal boron nitride nanosheets are subjected to surface functionalization treatment by synthesizing a multifunctional modifier, so that the dispersity and interface bonding performance of filler in a resin matrix are remarkably improved, and the coating has excellent insulativity, strong adhesive force, good flame retardance and outstanding corrosion resistance at the same time.

The invention relates to an all-vanadium redox flow battery positive electrode electrolyte additive, a preparation method, a positive electrode electrolyte and application, and relates to the technical field of all-vanadium redox flow battery electrolytes.The all-vanadium redox flow battery positive electrode electrolyte additive comprises a main chelating agent, an auxiliary chelating agent, a pH buffering agent and a dispersing agent, the main chelating agent is selected from one or more than two of citric acid, tartaric acid, 1-hydroxyethylidene-1, 1-diphosphonic acid and trisodium methylglycine diacetate, and the auxiliary chelating agent is selected from one or more than two of disodium ethylene diamine tetraacetate, trisodium nitrilotriacetate and tetrasodium glutamate diacetate; the mass ratio of the pH buffering agent to the main chelating agent to the auxiliary chelating agent to the dispersing agent is (3.6-4.1): (0.6-1.5): (2.5-3.2): (1.7-2.5). According to the positive electrode electrolyte additive for the all-vanadium redox flow battery, the electrolyte has a remarkable high-temperature anti-precipitation effect, the energy density and the electrochemical performance are not sacrificed, and the preparation process is simple and controllable.

The invention discloses an ultrahigh-temperature and high-salinity water-based guanidine gum fracturing fluid and a preparation method thereof. The guanidine gum fracturing fluid is prepared from a base fluid, a buffering agent, a cage-shaped molecule composite cross-linking agent and a gel breaker according to the mass ratio of 100: (0.1 to 0.6): (0.2 to 0.8): (0.01 to 0.08), the base solution is prepared from the following components in percentage by weight: 0.55 to 0.6 percent of a cyclodextrin modified thickening agent, 0.1 to 0.6 percent of a composite antioxidant, 0.4 to 0.8 percent of a multi-effect auxiliary agent, 0.1 to 0.2 percent of a sterilizing agent and the balance of hypersalinity water. According to the ultrahigh-temperature hypersalinity water-based guanidine gum fracturing fluid, through chemical modification of the guanidine gum thickening agent and synergistic interaction of various additives, the ultrahigh-temperature hypersalinity water-based guanidine gum fracturing fluid can resist the temperature of 200 DEG C, can be directly prepared by using hypersalinity water, realizes good fracture forming, sand carrying, temperature resistance and shearing resistance, and is low in filtration loss and damage; and the requirements of fracturing construction of ultra-deep ultra-high-temperature low-permeability reservoirs of offshore and onshore oil fields are met.

The invention discloses a high-density ceramic coating and a preparation method thereof, and relates to the technical field of polymer coatings, the high-density ceramic coating comprises, by mass, 33-35 parts of silica sol, 43-45 parts of a solvent, 0.35-0.42 part of a weak acid buffer agent and 18.5-19.9 parts of an auxiliary agent; wherein the solvent is prepared from the following components in parts by mass: 25.5 to 26.5 parts of MTMS, 0.5 part of deionized water and 16 to 19 parts of ethanol; the silica sol comprises 25.5-26.5 parts by mass of 45nm SiO2 sol and the balance of 15-20nm SiO2 sol, and the SiO2 sol is modified silica sol which is loaded by a metal organic framework or is subjected to in-situ growth of graphene quantum dots. The wear-resistant and high-temperature-resistant valve has the effects of wear resistance, high temperature resistance and long service life.