141 results about "Buffering agent" patented technology

The invention is about a method of marking ink which is only used to defend fake. The composition of it is: lipidol or lipid, surface active agent, integration agent, water, buffering agent. Their mass percents are: 1,2-hexylene glycol: 5%-15%, butanol: 1-5%, DH-1: 5-10%, EDTA: 0.1-0.5%, MS-1: 0.1-1%, water: the rest. The process is: a. dissolving the colorant in water, b. put the correct percent of 1,2-hexylene glycol and butanol into the solvent, then dropping the MS-1 and EDTA solution when mixing the solvent for 30-50 min, c. put the rest precent of water into the printing ink box. The picture and word would be shown red fluorescence in the UV but blank in the usual light.

A detection method for detecting a substance to be detected in an immunological test sample, the detection method comprising a labeling step in which a complex of the substance to be detected and a labeling body is formed in the presence of at least one selected from imidazole and derivatives thereof, a pH buffer, and a polyvalent metal ion, the labeling body comprising a first probe molecule capable of binding to the substance to be detected and a label.

This invention relates to the field of electroless plating technology, and more particularly to a low-phosphorus electroless nickel plating solution and a method for nickel plating on an aluminum alloy substrate. The low-phosphorus electroless nickel plating solution comprises the following components by mass concentration: a nickel ion source in the form of Ni... 2+ Calculated as 1.0~5.0 g / L; hypophosphite as H2PO2 ‑ The concentrations are calculated as follows: 20–45 g / L; glycine 5–40 g / L, gluconate 5–60 g / L; polyaspartic acid and / or its salts 0.2–5.0 g / L; pH buffer 2–25 g / L; alkyl glycosides 0.05–1.0 g / L; iodate stabilizer, in IO3... ‑ The concentration is calculated to be 0.2~5.0 mg / L. This invention maintains a high deposition rate and significantly improves the tolerance of by-products in the bath solution under low nickel ion concentration conditions. It is also free of heavy metals and sulfur-containing organic stabilizers, reducing the metal load and environmental risk of the waste liquid. It is suitable for various aluminum alloy matrices treated with double zinc replacement.

The application discloses an L-cysteine-based soil lead pollution leaching agent and a preparation method thereof, and belongs to the technical field of soil heavy metal pollution remediation. The L-cysteine-based soil lead pollution leaching agent comprises the following raw materials: an L-cysteine solution, a pH buffer and a polyvinylpyrrolidone solution; the concentration of the L-cysteine solution is 0.3-0.5 mmol / L, the concentration of the pH buffer is 1 mmol / L, and the mass fraction of the polyvinylpyrrolidone solution is 0.003%-0.005%; the volume ratio of the L-cysteine solution, the pH buffer and the polyvinylpyrrolidone solution is 1:1:0.15-0.4. The leaching agent has a remarkable leaching effect on soil lead, and the removal rate of the leaching agent on the contaminated soil with a Pb content of more than 500 mg / kg can reach more than 85%, so that the leaching agent can effectively prevent lead from migrating through the soil into a food chain or a water environment, and is much stronger than a traditional carboxyl-based leaching agent.

The present invention relates to novel compositions, in particular aqueous solution compositions having a pH in the range of 4.0 to 7.5 comprising: a peptide therapeutic agent; optionally one or more buffering agents, which are substances having at least one ionizable group with a pKa in the range of 3.0 to 8.5 and the pKa is within 2 pH units of the pH of the composition; and a stabilizer; wherein the peptide therapeutic agent does not contain an ionizable group with a pKa in the range of 3.0 to 8.5 and wherein the buffering agent(s) is present in the composition in a total concentration of 0 to 5 mM.

The application discloses an intermediate processing liquid for an electroless nickel immersion gold (ENIG) production line and a chemical gold preparation method. The intermediate processing liquid is applied between the electroless nickel plating and immersion gold processes, and comprises (a) a pH buffer and a metal ion complexing agent: a total concentration of 50-150 g / L; (b) an adsorptive corrosion inhibitor: a concentration of 0.5-5.0 g / L; (c) a low-foam non-ionic surfactant: a concentration of 0.01-10 g / L; (d) an auxiliary antioxidant: a concentration of 0.5-30 g / L; (e) a dissolving agent: a concentration of 1-50 ml / L; (f) a pH regulator: an appropriate amount, which is added to maintain the pH value of the intermediate processing liquid at 4.0-6.5; and (g) deionized water: a balance, so that the concentrations of the above components reach the set target values; and the intermediate processing liquid has a design use temperature of 20-45 DEG C. The intermediate processing liquid removes residual nickel ions on the board surface and in micropores through strong complex cleaning, and blocks the pollution to the subsequent gold tank; meanwhile, the preferential adsorption of the corrosion inhibitor molecules at the nickel layer grain boundaries forms a controllable molecular-level protective film, effectively adjusts the immersion gold replacement reaction kinetics, and prevents the occurrence of intergranular corrosion (black plate).

Provided herein are pharmaceutical compositions comprising a recombinant adeno-associated virus (AAV), a salt excipient or buffer, a sugar, and a surfactant. Also provided herein are methods for treating or preventing a disease in a subject in need thereof by administering to the subject a therapeutically effective amount of the pharmaceutical compositions.

The present invention relates to a stable liquid pharmaceutical formulation comprising 40 mg / mL to 200 mg / mL of an antibody against CSF-1R; 0.01% (w / v) to 0.1% (w / v) of surfactant; 5 mM to 100 mM of a buffering agent; and 10 mM to 500 mM of at least one stabilizer; at a pH in the range of 4.5 to 7.0.

This invention discloses a method for preparing high-purity Si-75, comprising: S1, adding sodium sulfide, sulfur, and deionized water in a molar ratio of 1:(1.0~1.1):(5~8) to a reaction vessel, adding a buffer, and reacting at 80~90℃ for 1~2h; S2, adding a phase transfer catalyst and a hydrolysis inhibitor to the system, adding γ-chloropropyltriethoxysilane dropwise, and reacting at 85~95℃ for 3~5h, allowing the mixture to stand and separate into layers after the reaction, to obtain an organic phase; S3, subjecting the organic phase to short-path distillation and then filtering to obtain high-purity Si-75. Compared with existing technologies, this invention uses a phosphorus-free buffer system, which simplifies waste treatment. It uses water as the reaction medium and does not use large amounts of organic solvents, making it suitable for continuous industrial production. By adding hydrolysis inhibitors, hydrolysis can be effectively prevented during the reaction, increasing safety. The short-path distillation method provides high purification efficiency and can quickly remove impurities. The product has a disulfide content of ≥98.5% and a color of 0 (Gardner color number), which is of great significance to the light-colored rubber industry.

The application discloses a concentrated tomato product for assisting in reducing blood fat and a preparation method thereof. The concentrated tomato product is prepared from the following raw materials in parts by weight: mature red tomatoes 800-1000 parts, phytosterols 8-12 parts, composite dietary fibers 3-8 parts, Omega-3 fatty acid microcapsules 2-6 parts, antioxidants 0.5-1.2 parts, stabilizers 0.3-0.8 parts, and edible buffer agents in an appropriate amount. The concentrated tomato product is concentrated juice or powder. The soluble solid content of the concentrated juice is 35-40 Bx, and the moisture content of the powder product is 5.0%. The application combines phytosterols, composite dietary fibers, Omega-3 fatty acid microcapsules and other natural functional components, and the components play a synergistic effect through different blood fat reduction mechanisms, thereby comprehensively assisting in regulating lipid indexes such as cholesterol and triglyceride. The blood fat reduction effect is significantly better than that of single-component products and ordinary tomato products, and the health needs of people with high blood fat can be met.

The application discloses a lyophilized powder of Evf and a preparation method thereof. The lyophilized powder comprises recombinant human acidic fibroblast growth factor, excipient, protein protective agent, pH buffer and lyophilized preparation maintenance agent. The lyophilized powder prepared by the method has high stability and is not easy to be broken into powder in the shaking process, so that electrostatic is avoided due to the friction between the broken powder and the bottle wall in the storage and transportation process, and the product quality is improved.

This invention relates to a low-corrosion water-soluble cleaning agent for aluminum alloys, containing the following components by weight percentage: 8-15% composite surfactant; 3-8% weak alkaline buffer; 2-6% aluminum alloy-specific composite corrosion inhibitor; 1-4% chelating cleaning aid; 1-3% co-solvent; 0.05-0.3% defoamer; 0.1-0.5% bactericide and preservative; and the balance being deionized water. It features non-corrosion properties on aluminum alloys, high cleaning efficiency, good corrosion and rust prevention, and environmental safety. It can quickly remove contaminants from the workpiece surface at room temperature while maintaining the workpiece's shine, extending the cleaning agent's service life, and is suitable for the cleaning needs of precision aluminum alloy workpieces.

The application discloses a fluorescent whitening functional auxiliary and a production process thereof, and relates to the technical field of functional dyes. The fluorescent whitening functional auxiliary comprises the following raw materials in parts by weight: 35-45 parts of a fluorescent whitening agent, 8-10 parts of gamma-cyclodextrin, 4-6 parts of a pH buffer, 2-3 parts of a dispersing agent, and 50-70 parts of deionized water. In the application, L-cysteine is reacted with 2-methyl-2-propenoic acid-2,2,6,6-tetramethyl-4-piperidyl ester to generate a sulfide compound, 4,4'-diaminostilbene-2,2'-disulfonic acid is reacted with cyanuric chloride to generate a monosubstituted compound, the monosubstituted compound is reacted with 7-hydroxy-4-methylcoumarin to generate a disubstituted compound, and the disubstituted compound is reacted with the sulfide compound to generate the fluorescent whitening agent. The fluorescent whitening functional auxiliary prepared in the application has excellent dispersibility, stability and anti-aging performance.

The application provides an aluminum alloy low-temperature oxidation hole sealing reagent and a preparation method thereof, and relates to the technical field of aluminum alloy surface treatment. The aluminum alloy low-temperature oxidation hole sealing reagent comprises the following raw materials in parts by mass: 2-9 parts of lithium salt, 0.1-1 parts of surfactant, 0.2-5 parts of alcohol, 0.5-1 parts of pH buffer, 0.5-5 parts of corrosion inhibitor, 0.5-5 parts of dispersant and 80-100 parts of water. The aluminum alloy hole sealing treated by the reagent has small hole sealing weight loss, high corrosion resistance and high pollution resistance.

The invention relates to a composition and method to increase survival of fish following catch-and-release events. The composition comprises an energy substrate and a hydrocolloid. The composition may comprise an application-safe buffer. The energy substrate may be a glycolysis metabolite, a Krebs cycle metabolite, an amino acid, a nitric oxide donor, a triglyceride, and mixtures thereof. The hydrocolloid may be a polysaccharide. The composition may include an oxygenated substrate, a trophic hormone, a stress reducing additive, a chelating agent, an antimicrobial preservative, and a color additive, and mixtures thereof. The method comprises after catching the fish, applying the composition to the fish and releasing the fish back into the wild. The composition may alternatively be mixed with a flotant or a cured polymer in the shape of a lure such that composition may be dispersed onto the oxygen exchange tissue of the fish when it is caught.

Capture mixtures and activated capture mixtures are provided that are useful for nucleic acid separation and purification are provided. The mixtures comprise lithium lauryl sulfate, lithium hydroxide, a zwitterionic sulfonic acid buffering agent, and optionally, proteinase K, capture probes comprising a first specific binding partner (SBP), and a second specific binding partner immobilized to a solid support. Related combinations, methods, uses, and kits, are also provided.

This invention belongs to the field of polymer material synthesis technology, specifically relating to a core-shell vinyl acetate emulsion for interior walls and its preparation method. Addressing the problems of insufficient scrub resistance and low efficiency in introducing functional monomers in existing vinyl acetate emulsions, the following solution is provided: A pre-emulsion A is obtained by emulsifying deionized water, a composite emulsifier, and a pH buffer with a core-layer mixed monomer mixture. The core-layer mixed monomer mixture includes vinyl acetate, vinyl tert-carbonate, C1-C4 alkyl esters of (meth)acrylate, a carboxylic acid functional monomer containing double bonds, diacetone acrylamide, and organosilicon-modified monomers. After seed emulsion preparation and core-layer polymerization, a shell-layer monomer mixture B (containing phosphate-based adhesion-promoting monomers, hydroxyalkyl esters, and vinyl acetate) is introduced for shell-layer polymerization. Post-treatment yields the emulsion. The emulsion possesses a hard core-functionalized soft shell structure, and the resulting interior wall coating can withstand over 8000 scrub cycles, far exceeding the national standard for superior products. Furthermore, the emulsion exhibits excellent storage stability.

A self-preserved mild liquid detergent composition useful for laundry applications is disclosed. The liquid detergent composition contains the following components: glycerin, which is present in the detergent composition at less than 30 wt % based on the total weight of the liquid detergent composition; at least one anionic surfactant; at least one non-ionic surfactant; ethanol in an amount of 0.1-4 wt % based on the total weight of the liquid detergent composition; at least one buffer; and water in an amount effective to provide a water activity (wa) above 0.8 and up to 0.95 (0.8<aw≤0.95), thus enabling it to be self-preserved. Significantly, the liquid detergent composition does not contain a preservative.

Disclosed is an efficacious, low-pH skin care composition that provides good sensory properties and has a low skin irritation potential. The low-pH composition includes an effective amount of a vitamin B3 compound and, optionally, one or more additional skin care actives to provide a skin health and / or appearance benefit. The low-pH composition also includes a pH buffer comprising lactic acid and sodium lactate, a polymer thickener comprising polyacrylate crosspolymer-6, and a silicone fluid having a kinematic viscosity of 100 cSt or less at 25° C. The pH of the low-pH composition can range from 2.0 to 5.0.

This invention discloses a core-shell type acrylate soap-free emulsion, its preparation method, and water-based ink, belonging to the technical field of the printing industry. The method includes: adding a solvent to a reaction flask, adding a first monomer and an initiator dropwise to the reaction flask, maintaining the temperature, adjusting the pH to 8, and adding deionized water to disperse and obtain a macromolecular acrylate emulsifier; mixing the macromolecular acrylate emulsifier, a portion of the second monomer, and deionized water, stirring to obtain a pre-emulsion; then heating the pre-emulsion, adding a portion of a pH buffer and a portion of ammonium persulfate to initiate the reaction; after blue light appears, simultaneously adding the remaining second monomer, the remaining ammonium persulfate, and the remaining pH buffer; maintaining the temperature; and adjusting the pH to 8. The core-shell type acrylate soap-free emulsion obtained by this invention, when used in water-based inks, can significantly improve coating adhesion, gloss, dry / wet rubbing resistance, anti-blocking properties, water resistance, and storage stability.

The present invention relates to the use of a liquid aqueous composition comprising a tonicity agent, a buffering agent, a non-ionic surfactant and a polysaccharide, and having a pH of from 5 to 7, for solubilization and stabilization of an antibody-drug conjugate during a period T equal or greater than 3 months at a temperature Θ of from 2° C. to 8° C.

The invention provides a pharmaceutical composition of a sulfonylurea derivative. Specifically, the present disclosure provides a pharmaceutical composition comprising a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, a stabilizer and a buffer agent. The composition has excellent stability. = = =

This invention relates to a Ni-W-SiC electroplating solution, a composite coating, its preparation method, and its application. The Ni-W-SiC electroplating solution provided by this invention includes a pre-plating solution and a composite plating solution. The pre-plating solution includes NiSO4·6H2O, a buffer, and a conductive salt. The composite plating solution includes NiSO4·6H2O, Na2WO4·H2O, Na3C6H5O7·2H2O, NH4Cl, SiC nanoparticles, and a dispersant. The composite coating is formed on the surface of a metal substrate by electroplating. After vacuum heat treatment, its Vickers hardness is 650HV~780HV, and its bonding strength is 45MPa~58MPa. This invention solves the problems of low hardness, high brittleness, and insufficient bonding strength of Ni-SiC coatings, and overcomes the defects of heavy pollution and high energy consumption associated with hard chrome plating. The resulting coating has high hardness, high bonding strength, wear resistance, and is environmentally friendly, making it suitable for surface strengthening of industrial rolls.

Provided is a nickel plating solution in which a ceramic substrate is less likely to be eroded. The plating solution of the present invention contains a nickel ion supply source, a sulfonic acid represented by formula 1: R-SO3H (R is an alkyl group or a hydroxyalkyl group having 1 to 5 carbon atoms) or a salt thereof, sodium hydroxide, and a pH buffer.

The invention relates to the technical field of dangerous solid waste treatment and resource utilization, in particular to an aluminum electrolysis overhaul slag fluoride enhanced leaching and resource recycling method. Comprising the following steps: adding pretreated overhaul slag into a complexing reaction solution of boric acid containing a dispersing agent and gluconate, and pulping; sealing the system, heating, and implementing pulse type micro-negative pressure degassing operation in which vacuumizing and normal pressure recovery are alternated during constant-temperature leaching; after the reaction is finished, carrying out thermal-state solid-liquid separation and tailing washing, and merging to obtain clear filtrate; crystal seeds are added into the filtrate, an aluminum source solution is dropwise added, the pH value is increased, solid-liquid separation is performed after constant-temperature curing, and synthetic cryolite is obtained; and supplementing the pH buffer agent to the clear liquid and then circularly returning to the liquid preparation process. According to the method, fluorine and aluminum are cooperatively extracted under the weak acid condition, generation of silicic acid gel is inhibited, equipment corrosion is reduced, mass transfer in pores is enhanced in combination with micro-negative pressure operation, and low-energy-consumption recovery of fluoride salt and closed-loop circulation of a working solution are achieved through pH regulation and control.

The invention claimed herein relates to a dielectric polishing composition and a method thereof. The invention claimed herein particularly relates to a composition comprising: (A) surface-modified colloidal silica particles comprising negatively charged groups on the surface of the particles, wherein the surface-modified colloidal silica particles have a negative charge, a particle size of 60 nm to 200 nm, and a zeta potential of < -35 mV at a pH in the range of > 2.0 to < 6.0; (B) at least one corrosion inhibitor selected from at least one guanidine derivative; (C) at least one iron (III) oxidizing agent; (D) at least one buffering agent selected from at least one basic amino acid having an isoelectric point (pi) of > 6.5; (E) at least one stabilizer; and (F) an aqueous medium, wherein the pH of the composition is in the range of > 2.0 to < 4.3, and wherein the composition has a polyacrylamide content of < 1 ppm.

This invention relates to the field of printed circuit board surface treatment technology, specifically to a highly stable chemical copper plating solution, comprising at least: 8-12 g / L copper salt, 9-13 g / L reducing agent, 25-32 g / L main complexing agent, 16-22 g / L auxiliary complexing agent, 0.2-0.35 g / L main stabilizer, 0.12-0.2 g / L auxiliary stabilizer, 0.1-0.18 g / L surfactant, and pH... The copper plating solution comprises: a regulator (18-25 g / L), a buffer (3-6 g / L), a corrosion inhibitor (0.08-0.15 g / L), and a flocculant (0.15-0.3 g / L). The main complexing agent is one or a mixture of ethylenediaminetetraacetic acid tetrasodium, ethylenediaminetetraacetic acid disodium, or sodium hypotriacetate. The auxiliary complexing agent is sodium gluconate. The main stabilizer is one or a mixture of 4,4'-bipyridine, 2-methylimidazole, or benzimidazole. The auxiliary stabilizer is one or a mixture of two of mercaptoethanol or 5-methylbenzotriazole. The copper plating solution provided by this invention ensures excellent copper plating performance while also having a long service life, effectively reducing maintenance frequency and copper plating costs.

This invention provides an environmentally friendly method for preparing a carpacacininib intermediate, belonging to the field of pharmaceutical intermediate technology. The method discloses an oxidation reaction of N-Boc-4-hydroxypiperidine as the starting material, yielding compound 2 under the action of an oxidant and a buffer. Compound 2 is then reacted with a cyaniding reagent in the presence of ammonium carbonate via a Bucherer-Bergs reaction to obtain compound 3. Compound 3 undergoes hydrolysis in an alkaline system at 80–110°C to obtain compound 4. Compound 4 is then reacted with di-tert-butyl dicarbonate to perform a Boc protecting group reaction, yielding the carpacacininib intermediate. This invention provides a method suitable for green and environmentally friendly industrial production to obtain the carpacacininib intermediate. This method avoids the use of highly toxic substances and precious metal catalysts, and achieves continuous reaction, thereby improving reaction efficiency and stability and reducing the formation of by-products. The overall yield of the four-step reaction can reach over 70%, and the product purity can reach over 99.4%.

This invention relates to the field of polymer materials technology, specifically to a high-temperature and humid heat-resistant water-based ink, its preparation method, and its application. The steps are as follows: S1, polybenzimidazole (PBI) powder is cryogenically ground to obtain nano-sized PBI powder; S2, deionized water, emulsifier, coupling agent, initiator, and defoamer are mixed and dispersed with the nano-sized PBI powder to prepare a PBI pre-dispersion; S3, deionized water, emulsifier, at least one of acrylic monomers and acrylate monomers, a functional amine, and a pH buffer are mixed to prepare a seed emulsion; S4, the PBI pre-dispersion is added dropwise to the seed emulsion, and in-situ polymerization is carried out in an emulsion polymerization apparatus to obtain a PBI-functional amine hybrid emulsion; S5, the PBI-functional amine hybrid emulsion is mixed and dispersed evenly with a defoamer, leveling agent, anti-abrasion agent, and water-based colorant to obtain a high-temperature and humid heat-resistant water-based ink. This invention improves the water resistance, heat resistance, and adhesion performance of the ink film under conditions of boiling, high-temperature sterilization, and high-temperature and humid heat.