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8966 results about "Stabilizing Agents" patented technology

Stabilizing agents are used for a number of functions in foods and the main function is to act as a thickening agent to gel the foods into the required consistency. Most stabilizing and thickening agents are polysaccharides (a kind of carbohydrate) examples of which are starches, gums, or proteins like gelatin.

Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof

In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of substantially water insoluble pharmacologically active agents (such as the anticancer drug paclitaxel) in which the pharmacologically active agent is delivered in the form of suspended particles coated with protein (which acts as a stabilizing agent). In particular, protein and pharmacologically active agent in a biocompatible dispersing medium are subjected to high shear, in the absence of any conventional surfactants, and also in the absence of any polymeric core material for the particles. The procedure yields particles with a diameter of less than about 1 micron. The use of specific composition and preparation conditions (e.g., addition of a polar solvent to the organic phase), and careful election of the proper organic phase and phase fraction, enables the reproducible production of unusually small nanoparticles of less than 200 nm diameter, which can be sterile-filtered. The particulate system produced according to the invention can be converted into a redispersible dry powder comprising nanoparticles of water-insoluble drug coated with a protein, and free protein to which molecules of the pharmacological agent are bound. This results in a unique delivery system, in which part of the pharmacologically active agent is readily bioavailable (in the form of molecules bound to the protein), and part of the agent is present within particles without any polymeric matrix therein.
Owner:ABRAXIS BIOSCI LLC

Jettable compositions

ActiveUS20050171237A1Prevent long-term corrosionAdditive manufacturing apparatusLiquid surface applicatorsMeth-Oligomer
A fully curable jettable composition having a viscosity less than 30 cps at a temperature within the range of 15-180° C., more preferably at a temperature of 15-100° C., e.g. 60-80° C. the composition comprising: (A) at least one low viscosity reactive resin selected from the group consisting of compounds containing an oxetane ring, cycloaliphatic epoxy resins, tetrahydrofurans, hexahydropyrans and mono-functional (meth)acrylates, said resin having a molecular weight of not greater than 300 Daltons, e.g. 250 Daltons or less, and a viscosity at a temperature in the said range of less than 30 cps, e.g. 5 to 15 cps; (B) at least one higher viscosity resin selected from the group consisting of epoxy resins, compounds containing an oxetane ring and acrylates, which resin acts to thicken the low viscosity resin and strengthen a jetted deposit of the composition, the higher viscosity resin having: a viscosity greater than twice that of the low viscosity resin at the said temperature in the range stated above, and a functionality of greater than or equal to 2; (C) at least one curable toughener, preferably having a functionality of at least 2, such as hydroxy, epoxy, acrylic or other reactive functionalised polymer/oligomer (e.g. derived by functionalising poly(tetrahydrofuran), polycaprolactone, polycarbonate diol, or a dendrimeric polyol; (D) at least one initiator for the polymerisation of the resins, and (E) at least one stabiliser for delaying the curing of the resins of the composition; wherein the low viscosity resin is slower to react than the higher viscosity resin and acts to solvate the higher viscosity resin prior to curing and at least partly during curing and wherein at least 30% of the components A and B are cationically curable resins. The composition can be jetted from piezo electric printing heads under the control of a computer program to form a multi-layered article, e.g. a three dimensional article, in which the adjacent droplets merge and are cured homogeneously together.
Owner:3D SYST INC +1

Flame-proof soft vinyl plastics for electric wire and cable

The invention relates to a piece of inflaming retarding soft polyvinyl chloride plastic used in electric wires and cables, which belongs to sheath and insulation materials used in electric wires and cables in industrial polymer materials and is composed of the raw materials with the following proportion by weight: 25 to 70 parts by weight of polyvinyl chloride resin 100 plasticizer; 5 to 40 parts by weight of co-polymerization resin, 3 to 12 parts by weight of stabilizing agent; 5 to 20 parts by weight of flame retardant I; 5 to 25 parts by weight of flame retardant II; 30 to 130 parts by weight of flame retardant III; 0 to 40 parts by weight of loading agent and 0.5 to 5 parts by weight of lubricant. The inflaming retarding soft polyvinyl chloride plastic used in electric wires and cables provided by the invention has very good inflaming retarding performance with the oxygen index as high as more than 46 and can meet the requirements of using the electric wires and cables with special inflaming retarding requirements as the sheath and insulation materials; the inflaming retarding soft polyvinyl chloride plastic not only has very good inflaming retarding performance but also has favorable low temperature resistant and embrittlement resistant performances and very good soft performance and processing performance.
Owner:CHANGSHU ZHONGLIAN PHOTOELECTRICITY NEW STUFF +1

Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD in cosmetic, food and pharmaceutical compositions

InactiveUS6485950B1Cosmetic preparationsNanotechIsozymeTurnover number
The invention relates to a novel purified isozyme of an autoclavable superoxide dismutase extracted from the plant Potentilla atrosanguinea Lodd. Var. orgyrophylla, said isozyme having the following characteristics, O2- scavenging activity remains same before and after autoclaving; scavenges O2- from sub-zero temperature of -20° C. to high temperature of +80° C.; O2- scavenging activity at 25° C. for 30 days without adding any stabilizing agent such as polyols or sugars; O2- scavenging activity in the presence of saline (0.9% sodium chloride) to 61.8% of the control (without 0.9% sodium chloride), stable at 4° C. for at least 8 months; contamination free and infection free from any living micro- and/or macro-organism after autoclaving; possesses temperature optima at 0° C.; possesses a molecular weight of 33 kD under non-denaturating conditions; possesses a molecular weight of 36 kD under denaturating conditions; has clear peaks in UV range at 268 and 275 nm; has an enzyme turnover number of 19.53x104% per nmol per min at 0° C.; and requires Cu/Zn as a co-factor, method for the preparation of the purified isozyme of autoclavable superoxide dismutase and formulations containing the said autoclavable superoxide dismutase.
Owner:COUNCIL OF SCI & IND RES

Completely degraded plant powder modified thermoplastics composite material and preparation method thereof

ActiveCN101760037AHas physical and chemical propertiesEasy to processThermoplastic compositesPolypropylene
The invention discloses a completely degraded plant powder modified thermoplastics composite material and preparation method thereof, which consists of the components with the weight portions as follows: 100 portions of degradable thermoplastics resin, 1-400 portions of plant powder, 0.1-40 portions of dispersing agent, 0.5-60 portions of impact modifier, 0-40 portions of inorganic filler as well as 0.1-10 portions of stabilizing agent. The degraded thermoplastics resin has similar physiochemical performances with universal polyethylene and polypropylene, has excellent processing performances, and can be commixed with plant powder to prepare thermoplastics wood plastic composite materials. The obtained thermoplastics wood plastic composite materials can be completely degraded into carbon dioxide and water in natural environment under the effects of broadly existed microbes like germs, actinomycetes, etc. Compared with wood products, the composite material has the characteristics of good durability and dimensional stability, easy forming, small water absorbability, and corrosion resistance; compared with plastic, the composite material has the characteristics of low cost and high rigidity. The completely degraded plant powder modified thermoplastics composite material can be used for producing the shells of electric apparatuses like TV, sound, copier, printer, etc, and can also be applied on other workpieces used for injection.
Owner:GUANGDONG KINGFA TECH CO LTD +2
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