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3645 results about "Dry powder" patented technology

Dry powder composition comprising long-chain RNA

The present invention is directed to a storage-stable formulation of long-chain RNA. In particular, the invention concerns a dry powder composition comprising a long-chain RNA molecule. The present invention is furthermore directed to methods for preparing a dry powder composition comprising a long-chain RNA molecule by spray-freeze drying. The invention further concerns the use of such a dry powder composition comprising a long-chain RNA molecule in the preparation of pharmaceutical compositions and vaccines, to a method of treating or preventing a disorder or a disease, to first and second medical uses of such a dry 10 powder composition comprising a long-chain RNA molecule and to kits, particularly to kits of parts, comprising such a dry powder composition comprising a long-chain RNA molecule.
Owner:CUREVAC SE

Composition with effects of protecting liver and resisting oxidation and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, and discloses a composition with liver protection and antioxidation effects and a preparation method thereof.The composition is prepared from galactosamine modified astragalus membranaceus exosome, schisandra chinensis nanocrystals, liquorice-chitosan nanoparticles, lactobacillus acidophilus freeze-dried powder, beta-(1, 3) / (1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate) sourced from saccharomyces cerevisiae, and beta-(1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate). And (6) a dextran, grape exosome-curcumin hybrid vesicle freeze-dried powder, a curcumin-mitochondrial targeting peptide compound, a resveratrol-hydroxypropyl-beta-cyclodextrin inclusion compound and reduced panthenol. According to the liver-protecting and anti-oxidation composition disclosed by the invention, multi-dimensional intervention on liver protection is realized through an elaborately designed ternary system. The system is composed of a traditional Chinese medicine extract, a microorganism-plant exosome combination and a high-bioavailability antioxidant, all the parts have a synergistic effect, and the liver protection effect is remarkably improved.
Owner:BEIJING FUTAIMING BIOTECHNOLOGY CO LTD

Dry powder formulations of epinephrine and associated methods

Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
Owner:BELHAVEN BIOPHARMA INC

Concrete stirring and mixing device with automatic additive adding function

The utility model belongs to the technical field of concrete stirring equipment, and discloses a concrete stirring and mixing device with an automatic additive adding function, which comprises a rack and a stirring assembly arranged on the rack, the stirring assembly comprises a material storage barrel arranged on the rack; one end of the driving shaft is rotationally connected with the storage barrel, and the free end of the driving shaft penetrates through the top of the storage barrel; the crushing blade is arranged in the storage barrel, and the crushing blade is coaxially and fixedly connected with the driving shaft; the output end of the driving motor is fixedly connected with the driving shaft; according to the scheme, the driving motor drives the driving shaft and the crushing blades to rotate in the material storage barrel, and the shearing force generated by the blades of the crushing blades is utilized to crush and scatter agglomerated dry powder additives, so that the situation that a part of areas are not coagulated for a long time or the overall strength deviation is too large due to uneven dispersion of the retarders agglomerated with damp is avoided; the utility model solves the problem that the concrete additive is affected with damp and agglomerated.
Owner:KELAMAYI SANLIAN BUILDING MATERIALS CO LTD

Composition containing dendrobium officinale enzymolysis extract as well as preparation method and application of composition

The invention relates to the technical field of cosmetics, and provides a composition containing a dendrobium officinale enzymolysis extract, which is prepared from the following components in percentage by mass: 18 to 22 percent of dendrobium officinale enzymolysis extract, 9 to 11 percent of chitosan oligosaccharide, 6.5 to 7.5 percent of bionic moisturizing enhancer, 0.1 to 0.2 percent of sodium alginate, 0.05 to 0.15 percent of citric acid / sodium citrate buffer pair and 60.4 to 65.4 percent of solvent matrix. By combining low-temperature enzymolysis with a biological purification process, efficient extraction of dendrobium candidum polysaccharides and phenolic substances is realized, dendrophenol oxidation inactivation caused by high temperature can be effectively avoided, hydrochloric acid residues in chitosan oligosaccharide preparation are effectively removed, formula irritation is remarkably reduced, and the dendrobium candidum extract is more suitable for sensitive skin care; the components in the composition have a synergistic effect, the dendrobium officinale enzymolysis extract and the enzymolysis chitosan oligosaccharide form a composite moisturizing network, the moisturizing rate is remarkably increased, the oxidation resistance is remarkably improved, and the composition can be applied to products such as essence, masks and freeze-dried powder.
Owner:XINKANGMEI (FUJIAN) COSMETICS CO LTD

Pharmaceutical composition of paclitaxel dimer prodrug nanoparticles and traditional Chinese medicine compound and application of pharmaceutical composition

The invention relates to the technical field of biological medicine, and discloses a pharmaceutical composition of paclitaxel dimer prodrug nanoparticles and a traditional Chinese medicine compound and application of the pharmaceutical composition, and the pharmaceutical composition is composed of Qiyuansanlong prescription freeze-dried powder and paclitaxel dimer prodrug nanoparticles; wherein the paclitaxel dimer prodrug nanoparticles comprise one of NQO1 response type PTX dimer prodrug nanoparticles (PTX-Q-PTX NPs) or GSH (glutathione) response type PTX dimer prodrug nanoparticles (PTX-SeSe-PTXNPs), and the paclitaxel dimer prodrug nanoparticles comprise one of NQO1 response type PTX dimer prodrug nanoparticles (PTX-Q-PTX NPs) and GSH response type PTX dimer prodrug nanoparticles (PTX-SeSe-PTXNPs). According to the pharmaceutical composition disclosed by the invention, a traditional Chinese and western medicine synergistic treatment system is innovatively constructed, and the advantage of multi-dimensional synergistic interaction is shown. Firstly, an NQO1 / GSH double-response type intelligent release system is adopted, and a biomarker highly expressed by tumor tissue can be specifically responded to realize precise drug release, so that the PTX concentration in tumors is improved compared with that of a traditional dosage form, and meanwhile, the drug circulation time is prolonged. Secondly, the active ingredients in the Qiyuansanlong prescription freeze-dried powder can significantly down-regulate the PD-L1 expression level, synergistically enhance CD4 + T and CD8 + T cell infiltration, and form chemical-immune dual killing effects.
Owner:ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Preparation method and application of flexible solid hydrogen storage bed body

The invention relates to a preparation method of a flexible solid hydrogen storage bed body, which comprises the following steps: S1, mixing 74-90% by mass of hydrogen storage alloy powder and 3-16% by mass of carbon-based heat conduction material for 20-50 minutes in a mechanical stirring manner to obtain a dry powder mixture; s2, adding an organic silicon material with the mass fraction of 5-16%, and continuously mechanically stirring for 1-5 hours to obtain a non-dry powder mixture; and S3, carrying out vacuum drying on the non-dry powder mixture in the S2 at 60-100 DEG C for 8-20 hours, and naturally cooling to room temperature to obtain the required novel non-dry powdery hydrogen storage bed body. Through the synergistic effect of the hydrogen storage alloy, the expanded graphite and the double-liquid silica gel, the flexible solid hydrogen storage material is formed on the basis of optimizing the material ratio and the process sequence. The synergistic effect of the materials breaks through the defect that a traditional hydrogen storage bed body is too high in rigidity or in a loose powder state, and finally the hydrogen storage bed body has high hydrogen storage efficiency, stable cycle life and excellent safety performance.
Owner:CHENGDU HYDROGEN TECH CO LTD

Dry powder inhaler with a mixing element

The present invention provides a dry powder inhaler comprising: one or more doses of powdered medication; an outlet through which a user may inhale a dose of medication; an airway, and a mixing element located in the airway When a user inhales on the outlet, medication is entrained in an air flow and flows through the airway and out through the outlet. The mixing element is in the form of three generally orthogonal generally circular discs with a common centre.
Owner:VECTURA DELIVERY DEVICES LTD

Ultrasonic-assisted red pomelo polyphenol extraction method and application

The invention provides an ultrasonic-assisted red pomelo polyphenol extraction method and application. The polyphenol component in the red pomelo is extracted through the following steps: firstly, performing activation pretreatment on red pomelo dry powder by adopting a low-temperature plasma device, and destroying a cell wall structure so as to improve the accessibility of combined polyphenol; then cellulase, pectinase, hemicellulase and beta-glucosidase are added into a biodegradable deep eutectic solvent to synergistically hydrolyze the cell wall polysaccharide, and combined polyphenol is released; then applying pulse type ultrasonic wave to assist extraction under a low-temperature condition, so that polyphenol is fully dissolved out and enters the eutectic solvent; and finally, carrying out solid-liquid separation to obtain the red pomelo polyphenol extract. Compared with a conventional heat extraction method, the method has the advantages that the extraction rate of the polyphenol of the red pomelo is remarkably increased at a lower temperature, the degradation of the polyphenol is effectively avoided, and the content of the total polyphenol and the antioxidant activity are increased; the method is green and environment-friendly, and can be applied to the health industry as an antioxidant.
Owner:ZAOFENGDA HEALTH TECHNOLOGY CHONGQING CO LTD

Thixotropic cement paste and preparation method thereof

The invention belongs to the technical field of oil field well cementation cement paste, and particularly relates to thixotropic cement paste and a preparation method thereof. The thixotropic cement paste provided by the invention comprises water, a dry powder material, modified silica sol, a polymer fluid loss agent and other additives. The cement paste disclosed by the invention has the characteristics of viscoelasticity, no dispersion under water, thixotropy and leaking stoppage.
Owner:CHINA OILFIELD SERVICES LTD

Lactobacillus rhamnosus GS044, a freeze-dried powder thereof, and a probiotic in promoting growth and development and improving immunity

The application provides a lactobacillus rhamnosus GS044 and a lyophilized powder and a probiotic of the lactobacillus rhamnosus GS044 in application to promoting growth and development and improving immunity, and belongs to the technical field of microorganisms.The application provides a lactobacillus rhamnosus GS044 with a preservation number of CGMCC No.33713.The application further provides a method for preparing gamma-aminobutyric acid by using the lactobacillus rhamnosus GS044, and a lyophilized powder prepared by using the lactobacillus rhamnosus GS044, a probiotic and application of the lyophilized powder and the probiotic.The lyophilized powder and the probiotic prepared by the application can effectively promote growth and development and improve immunity.
Owner:天津芯源生物科技有限公司 +1

A fire-resistant cable

The present invention discloses a fire-resistant cable, which includes a conductor. A conductor shielding layer is arranged outside the conductor. An insulating layer is arranged outside the conductor shielding layer. An insulating shielding layer is arranged outside the insulating layer. A semiconductive buffer tape layer is arranged outside the insulating shielding layer. A composite copper tape shielding layer is arranged outside the semiconductive buffer tape layer. The composite copper tape shielding layer includes an inner shaped copper tape winding layer and an outer flat copper tape covering layer. The shaped copper tape winding layer is formed by winding copper tapes with a T-shaped cross-section, and adjacent winding turns overlap a part of each other. There are cavities between the T-shaped copper tapes and both the inner semiconductive buffer tape layer and the outer flat copper tape covering layer, and the cavities are filled with dry powder. The outside of several cable cores is a cable skin, and an insulating filling layer is arranged between the cable skin and the cable cores; through the formation of a composite fire-resistant structure, the cable can achieve the effect of layered heat insulation; the composite copper tape shielding layer forms cavities for accommodating dry powder, which can improve the heat preservation and heat insulation effect.
Owner:SHANDONG TAIKAI CABLE

Primer group and kit for simultaneously detecting multiple respiratory pathogen nucleic acids based on twenty-six PCR (Polymerase Chain Reaction)

PendingCN120350178AMicrobiological testing/measurementMicroorganism based processesEnterovirusParainfluenza virus pneumonia
The invention discloses a primer group and a kit for simultaneously detecting nucleic acids of various respiratory pathogens based on twenty-six PCR (Polymerase Chain Reaction). The kit comprises primer pool freeze-dried powder of influenza A virus (FluA), influenza B virus (FluB), respiratory syncytial virus (RSV), human parainfluenza virus (hPIV), mycoplasma pneumoniae (MP), novel coronavirus (SARS-CoV-2), human respiratory adenovirus (HADV), human respiratory nose / enterovirus (HRV / HEV), bordetella pertussis (BP), human coronavirus (HCoV), human bocavirus (HBoV) and chlamydia pneumoniae (CP), PCR (polymerase chain reaction) freeze-dried powder and a buffer solution. According to the kit, primer system optimization is carried out on various pathogens, brand new primers and probe pools are designed, clinical sensitivity and specificity can be achieved, and meanwhile, the kit is matched with a fully-closed full-automatic detection card box integrating sample treatment and amplification and is suitable for rapid detection of respiratory tract pathogens.
Owner:FLASHDX SHENZHEN INC

5-METHOXY-N,N-DIMETHYLTRYPTAMINE (5-MeO-DMT) FORMULATIONS

PendingUS20250193970A1Organic active ingredientsPowder deliveryDiseaseAlcohol abuse disorder
The present invention provides a dry powder formulation of 5-MeO-DMT or a pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable carriers or excipients. The formulations described herein may be used to treat a disease or condition, such as depression or alcohol use disorder in a subject in need thereof.
Owner:BECKLEY PSYTECH LIMITED

Dry powder inhaler with an outlet mesh

PCT designated stageWO2025252975A1Medical devicesMedical atomisersPharmacy medicinePowderJect Pharmaceuticals
The present invention provides a dry powder inhaler comprising: one or more doses of powdered medication; an outlet through which a user may inhale a dose of medication; an airway comprising a vortex chamber having a wall, an exit, a powder inlet channel, and optionally one or more bypass inlet channels, wherein the powder inlet channel and or the bypass inlet channels are tangential to the wall. A mesh is located at the exit of the vortex chamber. The mesh is formed from circumferential elements and radial elements which together define a plurality of openings. When a user inhales on the outlet, medication is entrained in an air flow and flows through the vortex chamber and the mesh in the airway and out through the outlet.
Owner:VECTURA DELIVERY DEVICES LTD

Compositions, devices, and methods for intranasal delivery of dry powder epinephrine

Intranasal dry powder epinephrine compositions are described herein. The compositions include epinephrine or a pharmaceutically acceptable salt thereof, as well as a stabilizing agent and a carrier. The stabilizing agent is operable to include citric acid, or a pharmaceutically acceptable salt derived therefrom. Such intranasal compositions as described herein are useful in the treatment of health conditions which threaten the central nervous system (CNS) and impede the actions of alpha and beta-adrenergic receptors. Such health conditions include anaphylaxis, bronchospasms, respiratory impairment, organophosphate poisoning, and major adverse cardiac events (MACE).
Owner:BELHAVEN BIOPHARMA INC

Method for producing bacillus velezensis by solid-state fermentation of distiller's grains

The invention discloses a method for producing bacillus velezensis through solid-state fermentation of distiller's grains, and belongs to the technical field of fermentation engineering. The preparation method comprises the following steps: carrying out acid-base modification, enzymolysis and stacking fermentation treatment on white spirit vinasse, adding bran and jerusalem artichoke powder, carrying out steam explosion, and adding corn steep liquor dry powder, urea and other substances to prepare a white spirit vinasse culture medium; and carrying out amplification culture on the bacillus velezensis subjected to activation and seed culture by using a white spirit vinasse culture medium, drying and collecting the bacillus velezensis. Experimental results show that the bacillus velezensis can be efficiently produced by utilizing the fermentation method provided by the invention, and the spore number of the bacillus velezensis is as high as 9.2 * 10 < 10 > cfu / g. The technical method for producing bacillus velezensis through fermentation effectively solves the problem of resource utilization of white spirit vinasse and the problems of high cost and sewage in the liquid fermentation process, and is low in fermentation cost and suitable for industrial production.
Owner:SICHUAN RUNGE BIOTECHNOLOGY CO LTD

Medical dialysis dry powder production whole process intelligent supervision method

The invention discloses a medicine dialysis dry powder production whole process intelligent supervision method, and belongs to the technical field of medicine production intelligent monitoring. The method comprises the following steps: collecting a raw material purity parameter, a mixing process microscopic parameter and a finished product performance index parameter in real time through a sensor array module; the data processing module performs preprocessing and feature extraction on the collected parameters; the deep learning model module carries out training based on the preprocessed parameters to generate a dynamic ratio adjustment scheme; the control module controls the raw material conveying amount of the production equipment according to the adjustment scheme; and the closed loop feedback module feeds back the adjusted finished product performance index parameters to the deep learning model module to form a dynamic optimization closed loop. The method further comprises an abnormity early warning step and a model iteration step, the whole-process intelligent supervision of the medicine dialysis dry powder production process is realized, the proportion can be automatically adjusted according to the purity fluctuation of the raw materials, the stable product quality is ensured, the production efficiency is improved, and the manual intervention requirement is reduced.
Owner:TESCON MEDICAL TECHNOLOGY (FUZHOU) CO LTD +1

Preparation method of white tomato exosome freeze-dried powder

The invention relates to the technical field of freeze-dried powder preparation, and discloses a white tomato exosome freeze-dried powder preparation method, which comprises: 1, manually picking white tomatoes 3-5 days after a color changing period, carrying out double-frequency ultrasonic cleaning, and pre-cooling in a 4 DEG C phosphate buffer solution containing 0.1% of vitamin C; according to the method, by virtue of an ultrasonic-cellulase synergistic crushing process, cells are mildly and efficiently crushed, so that the damage to an exosome structure is reduced, and the release efficiency and activity of the exosome are improved; the zebra fish embryo melanogenesis can be obviously inhibited, and the whitening and freckle-removing effects are relatively good.
Owner:KUNHAI BIOTECHNOLOGY (SANYA) CO LTD +1

Polymerization reaction kettle with dry powder catalyst feeding system

The utility model discloses a polymerization reaction kettle with a dry powder catalyst feeding system. The polymerization reaction kettle comprises a polymerization reaction kettle body, a feeding system, an emptying system, a nitrogen feeding system, a raw material feeding system and a vacuumizing system. The feeding system comprises a catalyst sampler and a catalyst feeder which are communicated through a first catalyst feeding pipe; the catalyst sampler and the catalyst feeder are both communicated with the first catalyst feeding pipe through a first pipeline joint; the catalyst feeder and the polymerization reaction kettle are communicated with a second catalyst feeding pipe through a second pipeline joint; the polymerization reaction kettle and the catalyst feeder are both communicated with the emptying system; the nitrogen feeding system is communicated with the catalyst feeder and the polymerization reaction kettle; the raw material feeding system is communicated with the polymerization reaction kettle and the catalyst feeder; and the vacuumizing system is communicated with the polymerization reaction kettle. According to the polymerization reaction kettle with the dry powder catalyst feeding system, disclosed by the utility model, catalyst residues are reduced, and the catalyst feeding accuracy is improved.
Owner:ZHEJIANG JINGBO POLYOLEFIN NEW MATERIAL CO LTD

Light energy-saving fireproof soil-based foam light soil and preparation method thereof

The invention discloses lightweight energy-saving fireproof soil-based foam lightweight soil, which is prepared from the following raw materials in parts by weight: 20 to 30 parts of magnesium slag powder, 20 to 30 parts of granulated blast furnace slag powder, 15 to 25 parts of iron tailing powder, 40 parts of soil, 6 parts of water glass, 10 parts of desulfurized gypsum, 0.28 to 0.43 part of polycarboxylate superplasticizer, 57 to 75 parts of water, 0.76 to 1.00 parts of AOS foaming agent, 0.16 to 0.26 part of HPMC foam stabilizer and 0.16 to 0.26 part of calcium stearate foam stabilizer. The preparation method comprises the following steps: 1, mixing and stirring dry powder; 2, preparing slurry; 3, preparing soil-based foam light soil; and 4, molding and curing in a mold. According to the invention, a three-dimensional skeleton dense structure is constructed by optimizing the composition and proportion of the raw materials, the soil-based foam light soil with low heat conductivity, low density and high strength is obtained, and the soil-based foam light soil is suitable for the fields of roof heat preservation, wall body, roadbed filling, abutment back, foundation pit, pipeline backfilling and landscape engineering.
Owner:SHAANXI ACAD OF ARCHITECTONICS

Fuel cell cathode catalyst and preparation method thereof

The invention discloses a fuel cell cathode catalyst and a preparation method thereof, and belongs to the technical field of fuel cells. The preparation method of the fuel cell cathode catalyst comprises the following steps: adding a modified multi-walled carbon nanotube into a chloroplatinic acid aqueous solution with the mass concentration of 5g / L, carrying out ultrasonic treatment at 30-50 DEG C for 1-2 hours, and then carrying out freeze drying; and putting the dry powder into a horizontal tube furnace, introducing inert gas as protective gas, heating to 450-500 DEG C, preserving heat for 1 hour, cooling to room temperature along with the furnace, and taking out to obtain the fuel cell cathode catalyst. The modified multi-walled carbon nanotube is MWCNT / PEI / 5-formyl-2-thiopheneboronic acid, and the 5-formyl-2-thiopheneboronic acid is grafted after the PEI is grafted on the surface of the MWCNT, so that the dispersity of the MWCNT can be obviously improved, the agglomeration phenomenon of the MWCNT is reduced, the dispersion is more uniform, the loading capacity of platinum is high, the electrocatalytic activity of the catalyst is obviously enhanced, and the dosage of platinum is reduced.
Owner:安徽明天新能源科技有限公司

Dry powder drag reducer for fracturing fluid and preparation method of dry powder drag reducer

The invention provides a dry powder drag reducer for fracturing fluid and a preparation method of the dry powder drag reducer, and belongs to the technical field of fracturing materials for well drilling, and the preparation method comprises the following steps: dissolving 4-bromobutyryl chloride and N-dodecyl methylamine in acetonitrile, heating and stirring for reaction, adding polyethylene glycol monomethyl ether acrylate and dichloromethane, stirring and purifying in a nitrogen atmosphere to obtain a dry powder drag reducer; a double-tailed hydrophobic monomer is obtained; uniformly mixing the core-shell SiO2 / Fe3O4 composite nanoparticles, an ethanol water solution, KH570 and an ammonia solution, stirring, and purifying to obtain modified SiO2 / Fe3O4; the preparation method comprises the following steps: adding acrylamide, acrylic acid, sodium 2-acrylamido-2-methylpropanesulfonate, a double-tailed hydrophobic monomer and modified SiO2 / Fe3O4 into water, uniformly mixing, adjusting the pH value, introducing nitrogen, mixing and stirring, adding an azo initiator, stirring, cooling, purifying, carrying out vacuum drying, and crushing into powder, thereby obtaining the dry powder drag reducer for the fracturing fluid. The drag reducer has certain heat resistance while achieving good drag reduction performance, and can be better applied to fracturing operation in the well drilling process.
Owner:SHAANXI LONGYU INT TECH GRP CO LTD

Preparation method of saccharomyces cerevisiae-sourced yeast beta-glucan

The invention belongs to the technical field of saccharomyces cerevisiae beta-glucan, and relates to a preparation method of saccharomyces cerevisiae-sourced yeast beta-glucan. The invention relates to a preparation method of saccharomyces cerevisiae-sourced yeast beta-glucan, which comprises the following steps: uniformly mixing a yeast raw material with a first solvent, and carrying out high-pressure homogenization to obtain a homogenized feed liquid; adding food-grade alkali into the homogenized feed liquid to carry out extraction reaction, centrifuging the obtained reaction extracting solution, and separating a heavy phase to obtain a heavy-phase insoluble cell wall extract; and continuously adding a second solvent for resuspension, adding a compound enzyme preparation, adjusting the pH value of the reaction system by using an acidic reagent, carrying out an enzymatic hydrolysis reaction, centrifuging after the reaction is finished, recovering a heavy phase, and drying to obtain the insoluble yeast beta-glucan dry powder. According to the preparation method of the yeast glucan, provided by the invention, the conventional preparation process flow is shortened, the environmental protection treatment pressure is greatly relieved, the production cost is effectively reduced, and the prepared yeast glucan is higher in purity and has a better industrial application prospect.
Owner:NANJING BIOTOGETHER

Milk-derived taste enhancing peptide as well as preparation method and application thereof

The invention provides an enzymolysis preparation method of a milk-derived taste enhancing peptide, which comprises the following steps: carrying out enzymolysis on a liquid dairy product by using flavourzyme and glutaminase, and then carrying out enzyme deactivation to obtain an enzyme-deactivated product; carrying out acidification centrifugation and ultrafiltration on the enzyme-deactivated product, and freeze-drying the separated effluent to obtain freeze-dried powder; and loading the freeze-dried powder, and separating by a glucose gel column. The product disclosed by the invention does not generate bitter taste, and compared with a sample which is not subjected to enzymolysis, the flavor level of an original skimmed milk product is enriched, and the sample subjected to enzymolysis has the mellow taste of caramel and frankincense. The method comprises the following steps: separating milk-derived taste active peptides from milk-derived taste active peptides, predicting delicate flavor, anti-oxidation and anti-inflammatory activity and ACE blood pressure lowering functional activity of separated peptide liquid through a model, performing taste verification on the peptides predicted to have taste activity through Fmoc solid-phase synthesis, and performing sensory verification on the milk-derived taste active peptides LSFD, EDIKQME, IKQMEAE and TEDELQDK after synthesis, so that the milk-derived taste active peptides are obtained for the first time and are subjected to sensory verification.
Owner:BEIJING TECH & BUSINESS UNIV

CRISPR / Cas12a-RPA-based sequence combination for rapidly detecting mouse hepatitis virus and kit thereof

The invention discloses a CRISPR / Cas12a-RPA (clustered regularly interspaced short palindromic repeats / CRISPR associated protein 12a-recombinase polymerase amplification)-based sequence combination for rapidly detecting mouse hepatitis virus and a kit thereof, and belongs to the technical field of biological detection The sequence combination comprises an RPA primer pair sequence, a crRNA sequence and an ssDNA probe sequence; the kit comprises an RPA primer pair sequence, a crRNA sequence and an ssDNA probe sequence, the kit further comprises a mouse hepatitis virus negative control standard substance, RNase-free water, an RPA reaction buffer solution, an NEB buffer solution, Lba Cas12a nuclease, dry powder RPA reaction microspheres containing recombinase polymerase and magnesium acetate with the concentration of 280 mM. The kit can be used for rapidly detecting the mouse hepatitis virus. The primer sequence combination provided by the invention is good in conservative property and specificity and relatively high in sensitivity, and rapid detection of the mouse hepatitis virus can be realized.
Owner:YUNNAN UNIV

Fire extinguishing system for energy storage battery compartment of energy storage power station

The invention discloses a fire extinguishing system for an energy storage battery cabin of an energy storage power station, and belongs to the technical field of fire fighting, the fire extinguishing system comprises a battery storage cabin, a cabin door is mounted outside the battery storage cabin through hinges, and a carbon dioxide generator and a fire extinguishing agent spraying box are fixedly mounted on the top surface of the battery storage cabin; an exhaust plate and a fire extinguishing agent spraying plate are arranged at the bottom of the carbon dioxide generator and the bottom of the fire extinguishing agent spraying box correspondingly and located on the inner side of the battery storage bin. According to the fire extinguishing device, the driving assembly and the extrusion assembly are arranged in a matched mode, through the design, the interior of the battery storage bin can be monitored in real time, when spontaneous combustion of a battery occurs, the fire extinguishing system can be controlled to be started in time to treat the spontaneous combustion condition, and the fire extinguishing mode of combining a dry powder extinguishing agent and carbon dioxide gas is adopted; the fire extinguishing effect can be greatly improved, meanwhile, gas and a fire extinguishing agent can be rapidly diffused and distributed in the cabin, and the actual application effect of the system is improved.
Owner:NANJING NENGHUAZHOU THERMAL POWER CO LTD

Bi-component magnesium phosphate cement spraying foaming material and preparation method thereof

The invention relates to a bi-component magnesium phosphate cement spraying foaming material and a preparation method thereof, the bi-component magnesium phosphate cement spraying foaming material comprises a component A and a component B in a dry powder mass ratio of 100: (70-80), the component A comprises dead burned magnesium oxide, slag, a water reducing agent, a thickening agent, a foam stabilizer and a carbonate foaming agent; and the component B comprises phosphate, fly ash and a retarder. During use, the component A slurry and the component B slurry are atomized and sprayed out through a double-head spray gun and are mixed outside a nozzle, a chemical reaction is immediately carried out, foaming expansion and condensation hardening are completed, and a lightweight porous structure is formed. Compared with the prior art, the problems that a single-component foaming material is out of control in foaming, hardened in advance, difficult to spray and the like are effectively solved, and rapid spraying forming of the inorganic thermal insulation material is achieved. The prepared material is adjustable in dry density and uniform in pore size distribution, has the characteristics of high strength, low heat conductivity, small shrinkage rate, high durability and the like, meets the A-level non-combustible standard, and can be widely applied to building wall and roof thermal insulation engineering.
Owner:SHANGHAI JIAOTONG UNIV

High-temperature wear-resistant crack-free high-entropy alloy and laser additive manufacturing method and application thereof

The invention discloses a high-temperature wear-resistant crack-free high-entropy alloy and a preparation method and application thereof, the molecular formula of the alloy is as follows: Fe < 11.9 > Co < 23.8 > Cr < 23.8 > Ni < 35.7 > Nb < 4.8 >, and a Laves phase exists in the microstructure of the alloy. The preparation method comprises the following steps: putting weighed powder into a ball milling tank for ball milling, uniformly mixing the powder, and then drying, sieving and drying for storage; 304L stainless steel is selected as a base material, a sand mill is used for polishing the surface of the base material so as to remove surface oxide skin until a bright surface is exposed, and oil stains on the surface are cleaned; and the dried powder is placed in a powder feeding tank in a laser system, high-purity Ar gas is used for feeding the powder to a round spot laser head for melting and stacking, and the high-temperature wear-resistant crack-free high-entropy alloy without cracks is formed through layer-by-layer continuous deposition. By adding the Nb element, a Laves phase capable of improving the high-temperature performance is formed in a matrix, a high-entropy alloy sample is prepared through the laser directional energy deposition technology, subsequent heat treatment does not need to be conducted on the high-entropy alloy sample, and the deposited alloy has the excellent wear resistance at the high temperature.
Owner:GUIZHOU UNIV +1

Particulate filters

Methods for treating a filter for filtering particulate matter from exhaust gas are disclosed in which a dry powder is sprayed towards an inlet face of the filter entrained in a primary flow of gas to pass through the inlet face to contact a porous structure of the filter. The back pressure of the filter is monitored during spraying of the dry powder and the spraying of the dry powder is stopped when the back pressure of the filter reaches a required value. The required value may equal an absolute back pressure, or a pre-determined target back pressure for the filter minus an offset pressure, or an estimated back pressure of the filter.
Owner:JOHNSON MATTHEY PLC