A powdered, dispersible composition having stable dispersibility over time is provided. The composition exhibits a characteristic 
glass transition temperature (Tg) and a recommended storage temperature (Ts), wherein the difference between Tg and Ts is at least about 10° C. (i.e. Tg-Ts is greater than 10° C.). The composition comprises a mixture of a pharmaceutically-acceptable 
glassy matrix and at least one pharmacologically active material within the 
glassy matrix. It may be further mixed with a powdered, pharmaceutically-acceptable carrier. It is particularly valuable in unit 
dosage form having a 
moisture barrier, in combination with appropriate 
labelling instructions. A process for producing a powdered dispersible composition is also provided, wherein the process comprises removing the 
solvent from a solution comprising a 
solvent, a glass former and a pharmacologically active material under conditions sufficient to form a 
glassy matrix having the pharmacologically active material within the matrix.