2 results about "OSTEOINDUCTIVE FACTOR" patented technology

The invention relates to the field of medicine and tissue engineering, more specifically to means and methods to boost the repair of epithelial cells, such as damaged lung tissue as is observed in diseases with defective lung repair including as chronic obstructive pulmonary disease (COPD). Provided is osteoglycin (OGN; Osteoinductive factor, mimecan), or a functional fragment thereof, for use as an agent to promote the regeneration of epithelial cells or epithelial tissue.

This invention relates to the field of bone repair technology, specifically to drug-loaded microsphere-modified porous calcium phosphate bone cement, its preparation method, and repair material. The solid phase of the porous calcium phosphate bone cement consists of a porous calcium phosphate bone cement matrix and drug-loaded microspheres dispersed therein. The porous calcium phosphate bone cement matrix has a three-dimensional interconnected pore structure, and the drug-loaded microspheres have a core-shell structure, with the outer shell being a biodegradable material and the core being a osteoinducing factor. This porous calcium phosphate bone cement utilizes porous CPC to provide space for bone integration, and the drug-loaded microspheres achieve long-term controlled release of the osteoinducing factor, achieving efficient bone defect repair through an integrated "bone conduction-bone induction-bone integration" process.