739 results about "Gel matrix" patented technology

The invention discloses a hydrogel compound, a preparation method and application, and belongs to the technical field of hydrogel. The hydrogel compound provided by the invention is prepared from the following raw materials: a hydrogel matrix, sodium glycerophosphate pentahydrate and a functional drug, the hydrogel matrix is prepared from chitosan, hydroxybutyl chitosan and methacrylated gelatin; the functional medicines comprise cannabidiol, tobramycin and acetylsalicylic acid; the hydrogel compound provided by the invention has excellent mechanical properties and water vapor permeability, also has excellent slow release property and wound healing ability, and can be widely applied to preparation of medicines for treating wounds. In addition, the preparation method of the hydrogel compound provided by the invention is simple to operate and beneficial to practical application.

The invention relates to a preparation method of a gel electrolyte with an efficient flame-retardant characteristic. The gel electrolyte is mainly composed of a gel matrix, a flame retardant and an electrolyte solution. The invention provides a method for preparing a flame-retardant gel electrolyte, and application of the flame-retardant gel electrolyte in energy storage equipment such as a lithium ion battery is described in detail. The flame-retardant gel electrolyte has excellent flame retardance, and the safety performance of a battery system can be effectively improved. The preparation method comprises the following specific synthesis steps: (1) firstly, mixing polyethylene oxide (PEO) with a solvent, then adding lithium hexafluorophosphate (LiPF6) electrolyte salt, and uniformly stirring to form a uniform solution; and (2) adding trifluoroethyl methacrylate and a PEGDMA initiator into the solution, carrying out polymerization reaction to form a composite skeleton, and infiltrating the electrolyte under the swelling action to finally form the gel electrolyte. And (3) drying the swelled gel electrolyte to remove redundant solvent and moisture, and then cutting and packaging to obtain the gel electrolyte with high flame retardance. The flame retardance of the electrolyte is remarkably improved by reducing the using amount of the electrolyte and polymerizing and curing the electrolyte.

The invention discloses multifunctional hydrogel for promoting healing of diabetic wounds and a preparation method of the multifunctional hydrogel. The multifunctional hydrogel is prepared from Ti3C2Tx-Ag, paeoniflorin (PF), a gel matrix oxidized konjac glucomannan (OKGM) solution and carboxymethyl chitosan (CMCS). The method comprises the following steps: mixing Ti3C2Tx powder with AgNO3 in deionized water, heating to boiling, adding a proper amount of a sodium citrate solution, reacting to obtain Ti3C2Tx-Ag (TA) powder, and mixing the powder with a paeoniflorin (PF) and oxidized konjac glucomannan (OKGM) solution and a carboxymethyl chitosan (CMCS) solution to prepare the KC-PF-TA hydrogel. The multifunctional hydrogel has excellent photo-thermal antibacterial performance, anti-inflammatory performance and angiogenesis promoting performance, shows a remarkable effect of promoting healing of diabetic wounds through the synergistic effect of Ti3C2Tx-Ag and paeoniflorin, and has good biocompatibility; the multifunctional nano-composite hydrogel disclosed by the invention has great application prospect and value in the field of wound repair materials.

The present application provides a keratin and a nucleic acid sequence encoding the same. The present application further provides a keratin gel dressing comprising the keratin of the present application, bFGF and a gel matrix.

The invention discloses an N-type gel ionic thermal battery, a quasi-solid gel electrolyte and a preparation method of the quasi-solid gel electrolyte, and belongs to the technical field of thermal regeneration batteries. The preparation method comprises the following steps: fully soaking polyacrylamide hydrogel in an electrolyte containing [Cu (NH3) 2] < + > / [Cu (NH3) 4] < 2 + > redox couple to obtain the quasi-solid gel electrolyte. And preparing the N-type gel ionic thermal battery by using the quasi-solid gel electrolyte. According to the prepared N-type gel ion thermal battery, the thermoelectric conversion performance such as thermoelectric potential and output power is remarkably improved through the synergistic effect of solvated structure entropy change generated by the oxidation-reduction reaction of the copper ammonia complex reaction couple and the quasi-solid gel electrolyte. The problems that research and development of an existing N-type gel ion thermal battery focuses on physical performance regulation and control of a gel matrix, thermoelectric contribution of an oxidation-reduction reaction cannot be effectively enhanced, and improvement of the Seebeck coefficient and the power density is limited can be effectively solved.

The invention belongs to the technical field of medical materials, and particularly relates to a tooth whitening composition and a preparation method thereof, the tooth whitening composition comprises the following components by weight: 5%-15% of hydrogen peroxide, 0.5%-1.5% of a gel matrix, 0.2%-1.0% of a thickener, 5%-10% of a humectant, 3%-8% of propylene glycol, 0.05%-0.2% of a chelating agent, 1%-3% of a sweetener, 0.1%-0.5% of sodium fluoride, and the balance of water. Aiming at the problems that an existing tooth whitening product is relatively low in pH value (most of 4.0-5.0), easy to irritate gingiva and sensitive in tooth manufacturing, and the existing tooth whitening product needs to be stored in a dark place at a low temperature and is short in whitening validity period, the pH value of the product is adjusted to 5.5-6.5, so that the product is close to oral saliva, the irritation can be reduced, the stability of the product can be ensured, the product is not easy to decompose, and the tooth whitening effect is good. Active ingredients are prevented from losing efficacy in advance, and the whitening validity period is prolonged.

The invention relates to colchicine transdermal delivery gel and a preparation method thereof. The colchicine transdermal delivery gel is prepared from the following components in percentage by weight: 0.3 percent to 0.7 percent of colchicine, 70.0 percent to 60.0 percent of a gel matrix, 29.5 percent to 39.5 percent of a dissolution promoter and 0 percent to 10 percent of a penetration enhancer. Wherein the gel matrix is prepared by dissolving a thickening agent in a mixed solvent of water and ethanol, the volume ratio of the water is 70%-10%, and the volume ratio of the ethanol is 30%-90%. According to the colchicine transdermal drug delivery gel provided by the invention, the colchicine transdermal drug delivery gel which is simple in formula and convenient to prepare is provided, and non-toxic and non-irritant materials are used, so that the irritation of colchicine oral preparations and injections is avoided, the toxic and side effects can be reduced, and relatively high drug delivery efficiency can be achieved.

The invention discloses shell-imitated mechanically-enhanced photonic crystal paper, a preparation method thereof and application of the shell-imitated mechanically-enhanced photonic crystal paper in repeatable printing. The photonic crystal paper is prepared from a zirconium phosphate layered material and soft gel through blade coating shear force induced self-assembly alternate arrangement. The photonic crystal paper disclosed by the invention has a shell-imitated brick mud structure, and meanwhile, zirconium phosphate and soft gel have a strong hydrogen-bond interaction, so that the photonic crystal paper has high tensile strength, high flexibility, high modulus and self-supporting property, and can support repeated printing. When an aqueous solution containing a hygroscopic solute is used as ink to carry out ink-jet printing on the photonic crystal paper, the gel matrix is swelled, the lattice spacing is increased, and a lasting multi-color printing effect is achieved. The selected zirconium phosphate layered material has good thermal stability, and meanwhile, the brick mud structure can reduce the oxygen transmittance, so that the photonic crystal paper has flame retardant property, and the storage safety is improved. The blade coating method is simple and rapid, so that continuous production of the photonic crystal paper can be realized.

The invention relates to the technical field of compositions, and provides a hair-blacking and hair-loss-preventing traditional Chinese medicine and trace element composition and a preparation method and application thereof.The preparation method includes the steps that traditional Chinese medicinal materials with the effects of nourishing the liver and kidney, nourishing blood and growing hair are selected, and a multi-step water extraction and alcohol extraction combined technology is adopted to prepare high-purity traditional Chinese medicine extract dry powder; meanwhile, soluble trace elements such as zinc, iron and copper are selected, the optimal proportion of the soluble trace elements, the iron and the copper is determined through a response surface optimization algorithm, and a synergistic activity system is formed. Then, a mixture of traditional Chinese medicines and trace elements is dissolved in a buffer solution, and the mixture is entrapped in lipidosome composed of phospholipid and cholesterol through an ultrasonic nanocrystallization process, so that a stable nanoscale composite carrier is prepared; and finally, uniformly mixing the liposome suspension with a gel matrix to prepare the liposome gel dosage form for scalp external use. The problems of random component proportion, poor permeability and lack of mechanism verification in the prior art are solved.

The invention discloses a preparation method of a high-strength semi-solid lithium battery diaphragm, and belongs to the technical field of battery diaphragms. The invention discloses a preparation method of a high-strength semi-solid lithium battery diaphragm. The preparation method comprises the following steps: S1, preparing an LLTO active skeleton with a 3D nano structure and preparing a gel matrix; s2, embedding the gel matrix into the active skeleton to form a rapid ion transport layer; s3, embedding the gel matrix into the inert skeleton to form a stable layer; and S4, combining the rapid ion transport layer and the stable layer together to form the semi-solid lithium battery diaphragm. The problems of battery deformation, liquid leakage and even low guarantee and safety performance caused by collision or high temperature in the using process in the prior art are solved, the performance of the semi-solid lithium battery diaphragm is enhanced, and the deformation of the internal structure of the battery is reduced, so that the overall stability of the battery is enhanced, and the service life of the battery is prolonged. Battery short circuit can be effectively prevented, and the battery is protected from being damaged, so that safe use of the battery is ensured.

The invention provides a production method of a konjak-series Qingqing diet, and belongs to the technical field of konjak-series Qingqing diet, and the production method comprises the following steps: forming a primary colloid through an accurately controlled hydration process, then introducing soybean and pea proteins, and carrying out thermal gelation treatment to construct a composite gel matrix; functional plant extracts such as curcumin, tea polyphenol and a grape seed extract are added, and the release efficiency of active ingredients is improved by adopting an ultrasonic-assisted extraction technology. The method further comprises the step of adding vitamin complex and calcium and magnesium trace elements, finally, high homogenization of the product is achieved through an innovative tree-shaped multi-cavity homogenization treatment mechanism, the mechanism adopts a minimum spanning tree algorithm to optimize a fluid transmission path, and the technical problem of efficient compounding of the konjak gel and the functional plant extract is successfully solved.

The invention relates to the technical field of composite hydrogel preparation, in particular to a nano composite hydrogel preparation process based on a microfluidic technology. The gel comprises the following components in parts by mass: 50-70 parts of a gel matrix, 5-9 parts of a nano enhancement system, 8-14 parts of a functional carrier, 3-6 parts of a dynamic response system, 4-7 parts of a hyaluronic acid-sulfhydrylated heparin compound and 0.5-1.5 parts of L-ascorbyl palmitate. Precise mixing and directional arrangement of all component materials on a micro-level are realized through a microfluidic technology, so that a nano reinforcing system and a functional carrier are uniformly distributed in a gel matrix, the synergistic effect of all the components is fully exerted, the mechanical property and the biological function of the gel are effectively improved, and the preparation method is suitable for industrial production. And quaternized chitosan nanofibers, a dynamic response system for responding to external environment change and a hyaluronic acid-sulfhydrylated heparin compound for promoting angiogenesis are introduced, so that the gel has the biological functions of resisting bacteria and promoting angiogenesis through a synergistic effect.

The invention discloses an active exosome stent coating based on traditional Chinese medicine enhanced secretion promotion and a preparation method and application thereof, and belongs to the technical field of biological medicine and interventional instruments. The stent coating comprises exosomes, wherein the exosomes comprise myocardial cell active exosomes and human mesenchymal stem cell active exosomes which are intensified and secreted by traditional Chinese medicines; wherein the traditional Chinese medicines comprise placenta extract, pilose antler extract, sheep myocardial peptide, sea cucumber peptide, lycium ruthenicum peptide, cnidium lactone, curculigo orchioides extract and morinda officinalis extract; the intervention concentration of each component added into cells is 2-50 [mu] g / mL; the light-cured gel matrix is prepared from methacrylated gelatin, a photoinitiator and polyether 127; tacrolimus; the final concentration of the exosome is 1 * 10 < 9 >-12 * 10 < 9 > particles / mL, and the final concentration of the tacrolimus is 5-25 mu g / mL. The coating can be coated on the surface of the poly-L-lactic acid degradable stent to prepare the degradable stent, and has obvious vascular repair promoting capability.

The invention relates to the technical field of bird repelling agents, in particular to a bird repelling agent based on thiocyanuric acid and a preparation method thereof, and the bird repelling agent is prepared from the following raw materials: thiocyanuric acid, modified beta-cyclodextrin, a magnetic powder synergist, a gel matrix, a synergistic aid, a solvent and a surfactant. The invention discloses a bird repellent based on thiocyanuric acid and a preparation method thereof, thiocyanuric acid is included through monoisocyanate modified beta-cyclodextrin, a magnetic powder synergist and a gel matrix are combined to form a'molecular inclusion-magnetic response-gel fixation 'triple-action system, and the problems that an existing bird repellent is short in time efficiency and poor in weather resistance are solved. The release time of the bird repellent is prolonged, the high bird repelling rate is still kept under the conditions of high temperature and rainwater, and the bird repellent is suitable for scenes such as farmlands and electric power facilities and has remarkable technical progress and practical value.

The invention discloses a nanofiber interwoven composite gel membrane for carbon dioxide separation and a preparation method of the nanofiber interwoven composite gel membrane. The nanofiber interwoven composite gel membrane comprises a nanofiber interwoven framework and a carbon dioxide-philic gel matrix layer, wherein the surface of the nanofiber interwoven framework is coated with the carbon dioxide-philic gel matrix layer; the carbon dioxide-philic gel matrix layer is formed by in-situ polymerization and gelation of a precursor solution containing an oxidizing agent, a cross-linking agent and a functional monomer on the surface of the nanofiber interwoven skeleton. The nanofiber interwoven composite gel membrane provided by the invention has excellent carbon dioxide permeability and selectivity. The invention also discloses an application of the nanofiber interwoven composite gel membrane in separation of carbon dioxide.

The invention discloses composite hydrogel as well as a preparation method and application thereof. The composite hydrogel comprises a gel matrix and a medicine component loaded in the gel matrix, the gel matrix is prepared from sodium alginate and chitosan; the drug component comprises luteolin nanoparticles and biological stem cells, the composite hydrogel takes sodium alginate and chitosan as a matrix, the luteolin nanoparticles are added as a drug, the biological stem cells are loaded at the same time, the composite hydrogel has the functions of resisting inflammation and bacteria and promoting wound healing, the dual treatment effects of the drug and the cells are achieved, and the composite hydrogel has a good application prospect. The composite hydrogel has good effect on promoting wound healing while having antibacterial and anti-inflammatory effects, the efficiency and quality of wound healing are remarkably improved through the synergistic effect of the two components, an innovative and efficient solution is provided for complex wound management, the treatment effect is improved, and the application prospect is wide. Important clinical significance and wide market application prospects are realized.

The invention belongs to the technical field of medical gel, and particularly relates to modified hydrogel for skin wound healing and a preparation method thereof.The modified hydrogel is prepared from, by weight, 2-5 parts of drug-loaded GDVLNs, 1-2 parts of chitosan, 0.6-1.5 parts of antioxidant, 0.2 part of LAP, 1.5 parts of MA, 18 parts of gel matrix and 100 parts of buffer solution, the drug-loaded GDVLNs prepared from the traditional Chinese medicine active ingredients and the ginseng vesicles have the functions of resisting oxidative stress, promoting angiogenesis, promoting cell proliferation and the like, and the MA modified hydrogel system can realize slow release and controlled release of the drug-loaded GDVLNs and play a long-acting healing promoting role.

The invention belongs to the technical field of thermoelectric materials and functional polymer materials, and particularly relates to thermoelectric hydrogel based on synergistic enhancement of zwitterions and a polar solvent as well as a method and application of the thermoelectric hydrogel. The thermoelectric hydrogel is obtained through the steps that a precursor solution is subjected to a polymerization reaction to form a gel matrix, then the gel matrix is soaked in a soaking solution, potassium ferricyanide / potassium ferrocyanide redox couple is introduced, and the thermoelectric hydrogel is obtained, and the precursor solution is prepared from acrylamide, N-isopropylacrylamide, dimethyl sulfoxide, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide and N, N-dimethylformamide. The photoinitiator is prepared by mixing N, N-dimethylformamide, 1-ethyl-3-methylimidazolium tetrafluoroborate, a zwitterionic monomer [2-(methylacryloyloxy) ethyl] dimethyl-(3-sulfopropyl) ammonium hydroxide, a cross-linking agent N, N '-methylene bisacrylamide, a photoinitiator and deionized water. The thermoelectric hydrogel prepared by the invention has high mechanical strength, high ductility and high Seebeck coefficient, and has better temperature resistance.

The present disclosure relates to a field of biomedical technology. Embodiments of the present disclosure provide a leonurine nanocomposite hydrogel and preparation method and application thereof, including: dissolving dopamine (DA) monomers and inducing oxidation and self-polymerization of the DA to obtain polydopamine (PDA) nanoparticles, grafting thiol polyethylene glycol folic acid (SH-PEG-FA) on a surface of the PDA nanoparticles to obtain folic acid polydopamine (FA-PDA) nanocarriers; loading a leonurine (Leon) using the FA-PDA nanocarriers of the step 1 to obtain FA-PDA@Leon; encapsulating the FA-PDA@Leon of the step 2 into a gel matrix to obtain gel@FA-PDA@Leon hydrogel.

The invention discloses injection type facial filler composition gel for medical beauty as well as a preparation method and application of the injection type facial filler composition gel, and belongs to the technical field of biomedical materials. The composition gel comprises a combined gel matrix and polycaprolactone microspheres, wherein the combined gel matrix comprises an aqueous solution for injection, sodium carboxymethyl cellulose and human recombinant collagen; according to the composition gel, a combined gel matrix and polycaprolactone microspheres are mixed according to a specific proportion, amino acid residues of human-derived recombinant collagen in the combined gel matrix serve as binding sites of cell surface receptors to improve the cell recognition and attachment capacity of the polycaprolactone microspheres, and the amino acid residues are organically combined with sodium carboxymethyl cellulose to improve the cell recognition and attachment capacity of the polycaprolactone microspheres. The durability and biocompatibility of the shaping effect of the human-derived recombinant collagen at the injection site are improved; the composition prepared by the invention is good in gel fluidity, high in elastic modulus and high in dynamic viscosity, and can meet the expected mechanical and rheological properties of a facial filling agent for cosmetic and plastic surgery.

The invention provides a multifunctional flexible electronic device based on ionic liquid gel and patterned liquid metal and a preparation method. The preparation method comprises the following steps: firstly preparing ionic liquid gel with excellent performance as an upper substrate and a lower substrate of the flexible electronic device, then forming a high-resolution conductive pattern on the ionic liquid gel through a template printing method by using liquid metal alloy subjected to surface modification, and finally curing and packaging by using another layer of ionic liquid gel. According to the flexible electronic device, the modified particles are introduced to be mixed with the liquid metal, the flexible electronic device with the tensile adjustable resistance change characteristic is prepared, and meanwhile, the conductive patterns form firm interface bonding with the gel matrix through hydrogen bonds formed between the gallium with the oxidized surface and carboxyl of the ionic gel. Even if the prepared multifunctional flexible electronic device is stretched and released, the composite material can keep continuous contact with the base material, so that stable electric connection is maintained, and the method is suitable for the fields of wearable electronics and flexible electronics.

The invention discloses bee venom-containing skin essence with small irritation and a preparation method of the bee venom-containing skin essence. The skin essence is prepared from PLGA-PEG / liposome nanoparticles, a temperature-sensitive gel matrix, a protective agent, an antioxidant, a stabilizer and ultrapure water, the preparation method comprises the following steps: preparing the PLGA-PEG / liposome nanoparticles, preparing a poloxamer 407 solution, resuspending the nanoparticles, filling and storing. According to the invention, the melittin and the snake venom-like peptide have a synergistic effect on skin wrinkle resistance, so that the skin care effect is improved; pLGA-PEG / liposome nanoparticles are matched with a poloxamer solution to construct a dual sustained-release drug system, so that the irritation of drugs to skin is reduced, the lasting effect of the drug effect is improved, and the obtained skin essence has excellent moisturizing, whitening, anti-wrinkle and antioxidant capacities and is small in irritation.

The invention relates to the technical field of food processing and making, and discloses a konjac food and a making method thereof, and the making method comprises the following steps: raw material pretreatment, swelling and dispersion, enzymolysis treatment, gel matrix preparation, flavor substance embedding, mixing and degassing, curing forming, ultrahigh pressure treatment and post-sterilization and packaging. In the invention, the konjac micro-powder is subjected to controllable enzymolysis through the compound bio-enzyme preparation, and the konjac micro-powder and the gel matrix liquid composed of carrageenan, gellan gum and curdlan gum in a specific ratio have a synergistic effect under a curing condition, so that the konjac colloid and the gel matrix are interwoven to form a compact and stable cementing system, and the texture of the konjac food is improved; according to the method, the plant-derived flavor extract is added, so that the taste of the plant-derived flavor extract is uniform and consistent, the defect that the traditional process product is unstable in texture or easily generates bad flavor is overcome, the plant-derived flavor extract is embedded by adopting beta-cyclodextrin, and the plant-derived flavor extract is converted into a microcapsule form through high-pressure homogenization and spray drying processes.

The invention discloses a quick and long-acting gynecological antibacterial gel and a preparation method thereof. According to the formula of the gynecological antibacterial gel, a plurality of key components are selected and combined, and the gynecological antibacterial gel specifically comprises the following components in parts by weight: 5-15 parts of poloxamer, 0.5-1 part of carbomer, 0.5-1 part of N, N-dicarboxymethyl alanine trisodium salt, 0.2-0.1 part of carboxymethyl cellulose and 50-250ppm stable chlorine dioxide powder. The preparation method of the gynecological antibacterial gel comprises the five steps of chlorine dioxide chelating solution preparation, gel matrix preparation, gel forming, pH value adjustment and finished product packaging, all the steps are accurately controlled, and the product quality is ensured. The invention provides a gynecological gel product which is high in initial flowability, can be quickly gelated in vivo and has a quick long-acting antibacterial function, solves the problems of non-ideal antibacterial effect, inconvenience in use, insufficient safety and the like of an existing gynecological nursing product, ensures the safety and stability of the product, overcomes many defects of a traditional product, and has a good application prospect. And a better choice is provided for female reproductive health care.

The invention discloses a near-field dynamics simulation method for low-speed impact fracture of ultra-high performance concrete, which comprises the following steps: establishing a completely discrete model of a UHPC component, and realizing coupling of a concrete gel matrix and steel fibers through an Embedded method; a transition unit is introduced, a classic finite element unit and a PeriFEM local unit are connected through keys, force on the keys is modified, and coupling of the two methods is achieved; a continuous local unit is introduced, a motion equation of the local unit is deduced by adopting an explicit central difference algorithm, and an explicit algorithm based on the continuous local unit is constructed and used for solving the motion equation and calculating the damage condition of the UHPC matrix. According to the simulation method provided by the invention, the fracture process of the UHPC under low-speed impact can be effectively simulated, and a new solution of near-field dynamics and finite element coupling is provided.

The invention belongs to the technical field of contact lens care, and provides temperature-sensitive contact lens eye-moistening gel and a preparation method thereof. The temperature-sensitive contact lens eye-moistening gel is prepared from the following raw materials in parts by mass: a gel matrix, a surfactant, an osmotic pressure regulator, an active component, a chelating agent, a buffering agent and the balance of injection water, the composition of the gel matrix is defined. Chitosan, sodium hyaluronate and polyvinyl alcohol are compounded to serve as a gel matrix, a polyelectrolyte compound is formed, gelation time is shortened, gel strength and swelling resistance are improved, biocompatibility is improved, and drug-loaded delivery of active ingredients is achieved; the gel matrix and the surfactant are reasonably selected, the viscosity of the solution is increased, the gelation time is shortened, the excellent effect of relieving eye fatigue and dryness is achieved, the wearing comfort of the contact lens is remarkably improved, and the oxygen permeation effect of the contact lens is not obviously reduced after gel forming.

The invention discloses a novel compound rapid surface anesthetic and a preparation method thereof, and belongs to the field of pharmaceutical preparations. According to the anesthetic, core anesthetic components of lidocaine and tetracaine are compounded with propylene glycol-laurocapram synergistic penetration enhancer, menthol auxiliary penetration enhancer, carbomer 980 gel matrix, triethanolamine pH regulator, glycerol humectant, panthenol soothing agent, purified water and the like, a surface smearing agent is prepared through a specific process, and the anesthetic can be administered in combination with an iontophoresis technology. Compared with the existing surface anesthetic for the cosmetic surgery, the surface anesthetic disclosed by the invention solves the problems of slow effect taking and poor effect, can realize rapid penetration of local skin, has short anesthesia effect taking time, long duration and good effect, has no obvious irritation to the skin, has good product stability, can effectively reduce the drug toxicity, and has a good application prospect. The device is suitable for surface anesthesia of non-surgical medical beauty items such as skin beauty, laser treatment and water-light micro-needles.

The invention discloses a lactoferrin and antibacterial peptide bifunctional hydrogel dressing as well as a preparation method and application thereof. The hydrogel dressing is prepared by mixing lactoferrin, antibacterial peptide NZ2114, a magnesium lithium silicate gel matrix and water. The hydrogel dressing provided by the invention has the following advantages: 1) the hydrogel dressing is simple to prepare, low in cost and suitable for batch production; 2) the gel is convenient to apply, has a moisturizing effect, is long in residence time, good in biocompatibility, small in irritation, safe and reliable, or is accurately injected to the wound, moisturizes, slowly releases and efficiently improves the compliance of the body, and 3) the gel is good in antibacterial and anti-inflammatory effects, good in biocompatibility, free of irritation and capable of promoting wound healing, and only needs to be smeared on the surface of the wound.

The invention discloses a preparation method and application of a composite phase-change gel material, and the composite phase-change gel material is prepared by combining an organic phase-change material, an inorganic phase-change material or a combination of the organic phase-change material and the inorganic phase-change material with a nucleating agent, a cross-linking agent and a porous material and optimizing a process. The phase-change gel material with high phase-change latent heat, long-acting cooling, excellent shape stability, good flexibility and cycle durability is prepared. A polyurethane gel matrix is adopted, the material is endowed with good flexibility and toughness, high thermal storage capacity is provided through an organic phase-change material, and meanwhile, due to introduction of an inorganic phase-change material, the morphological stability is improved, and the cooling duration is optimized. The porous material is adopted to fix the phase-change material through the capillary adsorption effect, leakage is prevented, the heat conductivity is improved, and the cooling rate is increased. The material prepared by the process can be stably cooled for 2-4 hours within the range of 24-33 DEG C, is suitable for cooling pads, pillows, summer sleeping mats and other products, and has excellent use performance and market application prospects.

The invention discloses a method for preparing recoverable 3D microalgae gel and removing antibiotics in water, based on a 3D gel packaging technology, an isolation semipermeable membrane is constructed on the surface of a gel matrix, and a recoverable microalgae solid purification system is developed to cooperate with a mild environment provided by the gel matrix and the isolation effect of the semipermeable membrane. While the activity of the microalgae is protected and efficient biodegradation is realized, the leakage of the microalgae is prevented, and the potential microbial biohazard is restrained. Meanwhile, through the 3D printing technology, recoverable, low-cost, rapid and large-area industrial manufacturing can be achieved, the defects existing in traditional microalgae water treatment are overcome, and wide application prospects are achieved.