Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor or Smoke Producing Device Through Use of an Absorption Conditioning Unit

Abstract

A method for the administration of nicotine, THC, tobacco, cannabidiol or a base alkaloid includes administering in the oral or nasal cavity an absorption conditioning unit having at least two agents selected from the group consisting of (a) a buffer agent, (b) a capturing agent, (c) a penetration agent, and (d) a thermal agent, to the mammal, and then administering by inhalation a bioactive agent selected from the group consisting of nicotine, THC, cannabidiol and a base alkaloid. The absorption conditioning unit may be in a dosage form not containing a drug. The absorption conditioning unit may create a pH in the oral cavity or nasal cavity of 7.8-10 for a period of ten minutes or more after administration, the dosage form not containing an acid and not containing a drug.

Description

BACKGROUND[0001]Electronic vapor devices are increasingly popular with consumers. Such devices comprise electronic cigarettes, electronic pipes, electronic hookahs, personal vaporizers and other inhalator embodiments, both electronic and mechanical.[0002]UBS estimates that US e-cigarette sales will reach $500 million by the end of 2012, representing 100% growth from the preceding year (See UBS Tobacco Analyst Nik Modi's May 14, 2012 report entitled “Clearing the Smoke on E-Cigarettes,” the entirety of which is incorporated herein by reference). Arguably, the most well-respected tobacco analyst, Bonnie Herzog of Wells Fargo, has gone so far as to suggest in discussing Lorillard: “We remain very encouraged by blu [Lorillard's e-cigarette brand] and see huge upside potential given our belief ecigs could overtake traditional cigarettes in 10 years.” See Wells Fargo Lorillard Equity Research dated Oct. 24, 2012, the entirely of which is incorporated herein by reference. British American ...

AI Technical Summary

Benefits of technology

The present invention provides methods for administering nicotine, THC, tobacco, cannabidiol, cocaine, or a base alkaloid to a mammal, including humans. The methods involve administering an absorption conditioning unit that includes at least two agents selected from the group consisting of a buffer agent, a capture agent, a penetration agent, and a thermal agent, followed by inhaling the biological agent of interest, such as nicotine, THC, tobacco, cannabidiol, cocaine, or a base alkaloid. The absorption conditioning unit creates a pH of 7.8-10 in the oral cavity for at least ten minutes after administration and does not contain any acid or drug. The methods can provide a more efficient and effective way to administer these substances to mammals.

Problems solved by technology

Despite this rapid sales growth, it is understood that electronic cigarettes fail to deliver a steeply peaked blood plasma delivery of nicotine like the conventional cigarette does.