32 results about "Cannabidiol" patented technology

Compositions and methods are disclosed for treating one or more symptoms of perimenopause. A composition includes a cannabidiol, a Curcuma longa extract, and / or a Lepidium meyenii extract. A method of manufacturing a composition comprises including a cannabidiol, a Curcuma longa extract, and / or a Lepidium meyenii extract in the composition. A method of administering a composition includes administering a cannabidiol, a Curcuma longa extract, and / or a Lepidium meyenii extract of the composition.

Cannabinoid compositions formulated for use in the treatment of post-traumatic epilepsy (PTE) are disclosed. The compositions include cannabidiol (CBD), cannabigerol (CBG), and tetrahydrocannabinol (THC) as the major components therein, which may be isolated, purified or extracted from cultivars and blended together. The compositions include CBD, CBG and THC in certain ratios, formulated for the use in the treatment of PTE.

The present invention relates to a composition for preventing or treating periodontitis containing cannabidiol and taurine. The composition according to the present invention can effectively prevent or treat periodontitis by suppressing inflammatory factors and directly suppressing the loss of alveolar bone. In addition, it is safe for the human body and has almost no side effects, so it can be used in various ways as a material for medicines, quasi-drugs, or health functional foods.

The application belongs to the technical field of biological medicine, and more particularly relates to nanoparticles TK-PSBs / CBD@Met, a preparation method therefor and application thereof. The nanoparticles TK-PSBs / CBD@Met are nanoparticles formed by wrapping cannabidiol and metformin with thione-modified lung surfactant biomimetic liposomes. In vitro experiments have confirmed that the nanoparticles TK-PSBs / CBD@Met can effectively inhibit the fibrosis process of BEAS-2B cells induced by silicon dioxide. Animal experiments have shown that the nanoparticles TK-PSBs / CBD@Met can significantly improve the damage to the lung tissue structure and abnormal deposition of collagen caused by SiO2 exposure, and alleviate the pathological progression of silicosis fibrosis.

The present disclosure provides cannabinoid drug substances, pharmaceutical compositions and methods of treating neurological or neurodegenerative disorders in a human patient.

A method of treating or preventing a heart condition selected from the group consisting of acute myocarditis and acute pericarditis in a human subject in need thereof, the method comprising administering an effective amount of cannabidiol (CBD) to the subject.

The present invention relates to the use of cannabidiol (CBD) for the treatment of seizures associated with rare epilepsy syndromes. In particular the seizures associated with rare epilepsy syndromes that are treated are those which are experienced inpatients diagnosed with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) with DEPDC5 gene mutation. In a further embodiment the types of seizures include tonic, tonic-clonic and focal seizures without impairment. Preferably the dose of CBD is between 5 mg / kg / day to 50 mg / kg / day.

The invention relates to cannabidiol-based (CBD) formulations, and to their use in treating, preventing or alleviating pain, inflammation, an autoimmune disease, a neurological disease, neoplasm, or nausea in a subject. The invention also concerns low-dose CBD compositions, and extends to their use in methods of treatment.

Provided is a chiral cannabidiol (CBD) derivative drug, comprising four chiral derivatives, i.e., (7S)-(-)-CIAC001, (7R)-(-)-CIAC001, (7S)-(+)-CIAC001, and (7R)-(+)-CIAC001; and a use of the four chiral derivatives of CBD in the treatment of neuroinflammation and opioid addiction. Also disclosed are anti-neuroinflammation effects and the ability to regulate the activity of pyruvate kinase M2 (PKM2) of CBD analogs.

Disclosed are conjugate molecules formed from an active agent which is linked to a cannabinoid moiety through a specified linker having ester and amide end groups. The active agent can be a COX-2 inhibitor moiety, and the cannabinoid moiety can be a cannabidiol moiety. These conjugate molecules are contemplated to potentially be effective in the treatment of medical conditions.

This invention relates to novel pharmaceutical formulations, including solid oral dosage forms containing the non-psychoactive cannabidiol (CBD). The invention also relates to methods for preparing the pharmaceutical formulation and its application in treating diseases and conditions.

To provide an oral composition that is excellent in improving sleep quality and alleviating mental health problems. [Solution] An oral composition characterized by containing cannabidiol and at least one component selected from (A) to (D) below: (A) Sugars (B) Flavoring components (C) Amino acids (D) Alcohols having 3 to 12 carbon atoms (E) Aroma components

Disclosed are personal care compositions comprising cannabidiol dissolved in a carrier oil, e.g., hemp seed oil, and licorice extract, wherein the weight ratio of the cannabidiol to the licorice extract is in the range of from 1:6 to 1:40, as well as methods of using these compositions.

The application discloses a kind of Δ 8 - Synthesis method and Δ 8 - Application of THC. Wherein, the synthesis method comprises the following steps: taking cannabidiol as raw material, adding organic solvent, converting under ultraviolet light to generate Δ 8 - THC. According to the technical scheme of the application, cannabidiol CBD is converted into Δ 8 - THC under the catalysis of ultraviolet light, so that Δ 8 - THC appears as main product, and the method for converting CBD also ingeniously avoids complex and high-cost total synthesis route.

The present invention relates to a method for preparing cannabidiol by separation and purification using high-speed countercurrent chromatography, comprising: alcohol extraction and water precipitation, adsorption with a macroporous resin, and high-speed countercurrent chromatography separation. The present invention separates and obtains high-purity cannabidiol from industrial hemp flowers or leaves, while at the same time removing the psychotoxic component tetrahydrocannabinol by combining a microporous resin chromatographic column with a high-speed countercurrent chromatograph, and optimizing process parameters, and the solvent used therein being environmentally friendly, leaving no residues, having low cost and being recyclable. Therefore, the method is suitable for industrial production.

A pharmaceutical composition containing an effective amount of cannabidiol (CBD) for use in treating or preventing a heart condition, along with related methods and uses. The heart conditions include heart failure, acute myocarditis, toxicity caused by anti-cancer therapies, acute pericarditis, cardiac sarcoidosis, inflammatory cardiomyopathy, and atherosclerosis and related uses and methods. The disclosure shows CBD to be effective in (i) reducing cardiac hypertrophy; (ii) reducing cardiac fibrosis; (iii) reducing the level of BNP; (iv) reducing the level of cytokine IL1β; (v) reducing the level of cytokine IL6; (vi) reducing the level of CD69; (vii) increasing the level of cytokine IL10, and (viii) combinations thereof. The composition is preferably adapted for parenteral administration.

A composition for suppressing sebum synthesis, the composition including cannabidiol and salicylic acid.

The present invention relates to the use of cannabidiol (CBD) in the treatment of focal seizures. In one modality, patients suffering from focal seizures are children and young adults. CBD appears to be particularly effective in reducing focal seizures in patients with etiologies including Lennox-Gastaut syndrome; tuberous sclerosis complex; Dravet syndrome; CDKL5; neuronal ceroid lipofuscinosis (NCL); febrile infection-related epilepsy (FIRES) syndrome; Aicardi syndrome; and brain abnormalities, compared to other types of seizures. Significantly, CBD is also highly effective in reducing a subtype of focal seizures: focal seizures with deterioration.

CBD derivatives effective for treating opioid addiction, neurodegenerative diseases and neuroinflammation. The CBD derivatives have lower toxicity than CBD, are not addictive, and do not inhibit respiration or damage short-time memory.

The present disclosure relates to methods and compositions comprising cannabidiol (CBD) and a volatile anaesthetic, particularly isoflurane, useful for treating or preventing traumatic brain injury (TBI).

The present application relates to the use of cannabidiol in the preparation of a medicament for the treatment of coronavirus infection. In particular, the present invention relates to the use of cannabidiol, or a geometric isomer, pharmaceutically acceptable salt, solvate or hydrate thereof, or a pharmaceutical composition comprising any one or more of the above ingredients, in the preparation of a medicament for the prevention and / or treatment of a disease or infection caused by a coronavirus.

The application provides a kind of based on seven substitution 6-amino-6-deoxy-β-cyclodextrin cannabidiol nanosphere, preparation method and purposes, the method first prepares seven substitution 6-amino-6-deoxy-β-cyclodextrin (Aβ-CD) amination cyclodextrin carrier, then cannabidiol (CBD) is with carrier in ethanol-water mixed solvent according to certain proportion, by ultrasonic assisted inclusion+room temperature light shielding stirring to form stable inclusion system, by dialysis purification, freeze drying or spray drying, obtain the spherical nanoparticle of uniform particle size about 120 nm.The application solves the problem that CBD has very low water solubility, poor bioavailability, and insufficient in vivo circulation stability.The nanosphere obtained by the application has high encapsulation efficiency, which can significantly improve the solubility, dissolution rate and in vivo bioavailability of CBD.

The present invention discloses a method for extracting cannabidiol from dried, milled and decarboxylated hemp by submitting to a subcritical liquid carbon dioxide extraction followed by a mild liquid carbon dioxide separation.

The application provides a dressing for relieving pain and promoting healing of burn wounds and a preparation method. The dressing for relieving pain and promoting healing of burn wounds is composed of the following components in mass percentage: 8-10% of gelatin, 3-5% of sodium carboxymethyl cellulose, 0.1-0.3% of ferric chloride, 0.5-1% of dopamine, 0.15-0.25% of cannabidiol, 0.3-0.5% of 2-propanol, 0.05-0.1% of polylysine hydrochloride, 0.04-0.06% of vitamin E, 2-3% of trehalose and the rest of phosphate buffer. The dressing can obtain excellent effect of relieving pain and promoting healing of burn wounds through the synergistic cooperation of the components.

The invention relates to Cannabidiol or compositions of Cannabidiol for use in the treatment of infections caused by pathogens and parasites. The invention relates to use of Cannabidiol or compositions of Cannabidiol for the treatment of infections caused by pathogens, particularly those pathogens which are likely to activate either cGAS-STING pathway or 2',5'-oligoadenylate synthetase (OAS)-RNase L pathway. The invention relates to Cannabidiol or compositions of Cannabidiol for use in the prevention of infections / prophylaxis or priming animal or host for better preparing for infections.

The utility model discloses a centrifugal infiltration device for industrial hemp cannabidiol extraction, including infiltration cylinder, the surface of infiltration cylinder is established with mounting hole, the upper surface fixedly connected with the blanking cylinder of infiltration cylinder, the bottom of blanking cylinder is linked with the inside of infiltration cylinder, the inner wall rotationally connected with drive shaft of infiltration cylinder, the surface fixedly connected with a plurality of protection cylinder of drive shaft, the upper surface fixedly connected with the fixed plate of infiltration cylinder, the surface of fixed plate is provided with centrifugal discharge mechanism. The utility model industrial hemp raw material is placed in a plurality of protection cylinder after, through stainless steel wire net to its stop position, prevent hemp raw material under the action of centrifugal force, from the protection cylinder inside fling out, when infiltration operation, the liquid of blanking cylinder flows, and realizes infiltration operation through the water hole on multilayer protection cylinder and flows down, when the discharge, only need to open the arc baffle, and the industrial hemp in multilayer protection cylinder can be taken out, convenient and fast.

Cannabinoid compositions formulated for use in the treatment of complex regional pain syndrome (CRPS) are disclosed. The compositions include cannabidiol (CBD), cannabigerol (CBG), and tetrahydrocannabinol (THC) as the major components therein, which may be isolated, purified or extracted from cultivars and blended together. The compositions include CBD, CBG and THC in certain ratios, formulated for the use in the treatment of CRPS.