730 results about "Cannabidiol" patented technology

The present invention relates to the use of one or more cannabinoids in combination with one or more anti-psychotic medicaments for use in the prevention or treatment of psychosis and psychotic disorders. Preferably the one or more cannabinoids are taken from the group: cannabidiol (CBD); cannabidiolic acid (CBDA); tetrahydrocannbidivarin (THCV); tetrahydrocannbidivarinin acid (THCVA); cannabichromene (CBC); cannabichromenic acid (CBCA); cannabigerol (CBG) and cannabigerolic acid (CBGA). Preferably the anti-psychotic medication is an atypical anti-psychotic medication.

The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.

A method of treating a disease state or condition in humans via topical brainstem afferent stimulation therapy via the administration of a cannabinoid drug(s) to the back of the neck of a human patient to provide regional neuro-affective therapy is disclosed. In certain preferred embodiments, the cannabinoid drug(s) are not psychoactive or substantially not psychoactive. In certain embodiments, the cannabinoid drug(s) are incorporated into a pharmaceutically acceptable topical carrier, e.g., a cream. In certain preferred embodiments, the cannabinoid drug(s) comprises cannabidiol.

The invention discloses a method for extracting cannabidiol from industrial hemp floral leaves. The method comprises the following steps: grinding and drying floral leaves of industrial hemp, thereby obtaining medicinal powder; extracting the medicinal powder by adopting 30-100v% of ethanol, thereby obtaining extracting solution; concentrating the extracting solution to obtain extract; performing water precipitation on the extract, removing the impurities, thereby obtaining water precipitation solution; centrifuging the water precipitation solution, adding 10-100v% of ethanol into the obtained precipitate, dissolving to obtain an alcoholic solution of the precipitate; performing column chromatography on the alcoholic solution of the precipitate; concentrating the eluent obtained by eluting after column chromatography, adding ethanol to perform supersaturation dissolving, thereby obtaining a crystal; adding the crystal into purified water or ethanol for washing, thereby obtaining a primary product; uniformly mixing the primary product by using the purified water, drying, thereby obtaining the cannabidiol. According to the method disclosed by the invention, the highly safe ethanol serves as a solvent, so that the purity of the cannabidiol in the finished product is improved, a psychotoxic component, namely tetrahydrocannabinol, is removed, the product safety is improved, and the method is suitable for industrial production.

The invention relates to the use of cannabidiol (CBD), at a dose of greater than 300 mg/day, in combination with a standard anti-epileptic drug (SAED) which acts via sodium or calcium channels, for use in the treatment of epilepsy. The SAED is preferably one which•modifies low-threshold or transient neuronal calcium currents,or•reduces high-frequency neuronal firing and sodium-dependent action potentials and enhances GABA effects. Preferred SAEDs are ethosuximide and valproate.

The present invention relates to a novel pharmaceutical formulation comprising a ratioed mix of: (i) one or more compounds that acts as an inverse agonist of the CB1 and/or CB2 receptor; and (ii) one or more compounds that acts as a neutral antagonist of the CB₁ and/or CB₂ receptor. Preferably both the inverse agonist of the CB₁ and/or CB₂ receptor and the neutral antagonist of the CB₁ and/or CB₂ receptor are cannabinoids. Preferably the cannabinoids are tetrahydrocannabidivarin (THCV) and cannabidiol (CBD).

The present invention relates to the use of one or more cannabinoids in the manufacture of medicaments for use in 0 the treatment of diseases and conditions benefiting from inverse agonism of the CB₁ and/or the CB₂ cannabinoid receptor. Preferably the cannabinoid is a cannabidiol (CBD) type compound or derivative thereof.

The present disclosure relates to the use of cannabidiol (CBD) in the treatment of absence seizures. In particular, the disclosure relates to the use of CBD for reducing absence seizures in patients suffering with etiologies that include: Lennox-Gastaut Syndrome; Tuberous Sclerosis Complex; Dravet Syndrome; Doose Syndrome; CDKL5; Dup15q; Jeavons syndrome; Myoclonic Absence Epilepsy; Neuronal ceroid lipofuscinoses (NCL) and brain abnormalities. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).

The present disclosure relatesto the use of cannabidiol (CBD) for the treatment of seizures associated with Aicardi Syndrome. In one embodiment the seizures associated with Aicardi Syndrome are convulsive seizures; focal seizures with impairment or infantile spasm. The disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).

The invention discloses an extraction and separation method of cannabidiol. According to the method disclosed by the invention, the water solubility of the cannabidiol is enhanced through adopting analkaline solution and the cannabidiol is extracted and enriched by utilizing an organic solvent; then the cannabidiol is purified and enriched through a polyamide resin column, neutral aluminum oxideand a bonded silica gel column; then the cannabidiol is crystallized to obtain high-purity cannabidiol. The method disclosed by the invention is easy to operate, strong in practicability and suitablefor industrial popularization and application.

Use of a cannabidiol for the manufacture of a medicament identified for the treatment or prevention of diabetes and/or insulitis.

The present disclosure relates to the use of cannabidiol (CBD) for the treatment of of nocturnal snoring. In particular the CBD appears particularly effective in treating nocturnal snoring in children and young adults with epilepsy the disclosure further relates to the use of CBD in combination with one or more anti-epileptic drugs (AEDs).

The invention discloses an extraction method and an extraction device for cannabidiol-enriched industrial hemp essential oil. By adopting devices such as a screening machine, an oven, a soaking tank, a rotary evaporator, an ultrasonic agitation tank, a butterfly centrifuge, a first climbing-film evaporator, a proportioning tank, a pressurized chromatography silica gel column, an eluate tank, a second climbing-film evaporator, a rotary evaporator, a finished product tank and a solvent recovery tank which are sequentially connected by virtue of pipelines, industrial hemps are stepwise subjected to the operation steps comprising screening, baking, extracting, re-treating, filtering, monitoring, sampling, chromatography and concentrating to obtain the finished product and the effective component cannabidiol-enriched industrial hemp essential oil is finally extracted. By virtue of the extraction device disclosed by the invention, the defects of low efficiency, large consumption and inconvenience in scale production of the conventional process are overcome, the semi-finished product containing tetrahydrocannabinol in the processing does not artificially contact and flow, is legal, safe and efficient, the process method is simple and can be easily promoted and the product has high purity, complete active ingredients and low cost.

The present invention is generally directed to substantially pure cannabidiol, stable cannabinoid pharmaceutical formulations, and methods of their use.

This application discloses an anti-aging composition for dermal application comprising cannabidiol hemp oil, chuanxiong extract, mondo grass extract, Chinese foxglove extract, female and panax ginseng extract, dragon's blood resin, lilyturf root, and jojoba oil. Other active ingredients may include licorice root, Astragalus membranceus, tree peony, mulberry bark extraction, longan fruit, wild pansy, rose canina seed powder, and Radix polygoni multiflori. The composition is formulated with other components to serve as a cleanser, a moisturizer, a serum, a gel masque, an eye cream, a toner, or an exfoliant.

The invention relates to the use of a combination of cannabinoids for the treatment of Chronic Obstructive Pulmonary Disease (COPD). Preferably the combination of cannabinoids are cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC). More preferably the cannabinoids are in a predefined ratio by weight of approximately 1:1 of CBD to THC.

The invention described herein relates to a cannabis cultivar that produces high concentrations of cannabidiol. The invention further relates to preparations and products derived from the cannabis cultivar. Also provided are methods of treating conditions that are treatable by cannabidiol. by administering a preparation or product derived from the cannabis cultivar.

The invention belongs to the field of pharmaceutical and chemical industry, and specifically relates to a preparation method of high-purity cannabidiol. The preparation method is characterized by comprising the following steps: taking leaves of cannabis sativa and the plant top occupying one fifth of the whole plant as extraction parts, performing purification by using macroporous absorbent pillarchromatography and polyamide pillar chromatography joint technology, and performing crystallization refining by using a mixed solvent system, thereby maximally improving the yield in the premise of guaranteeing the acquisition of a high-purity product. According to the method provided by the invention, the CBD purity of the obtained product is high, the yield is high, the process is simple, and the industrialization is easy to realized.