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368results about How to "Small dose" patented technology

Inhalation spray of antivirus medicines

The invention relates to an inhalation spray of antivirus medicines. The inhalation spray comprises the following components in percentage by mass of 0%-30% of antivirus activity agents, 0%-30% of auxiliary agents, 0%-30% of taste masking agents and the balance solvents, wherein the content of the antivirus activity agents and the content of the auxiliary agents are not 0% at the same time. Compared with the prior art, the inhalation spray disclosed by the application has the purpose that during outbreak period of epidemic corona viruses and other viruses, people do not need to occupy medicalresources in short supply and only need to inhale the antivirus medicines into respiratory tracts, medicine administration is accurately targeted, and the objective of preventing virus infection and propagation can be achieved; in addition, through united medication of the antivirus activity agents and the auxiliary agents, besides, various medicines are inhaled into the respiratory tract of a patient, synergistic treatment effects are generated, the viruses are eliminated, and serious respiratory tract and infection and serious pulmonary infection caused by the viruses can be treated; and chloroquine type antivirus medicines and macrocyclic antibiotics are inhaled through spraying for united medication, and the dosage of the medicines can be notably reduced, so that side effects of prolonged QT intervals, Tdp and sudden cardiac death caused by the medicines can be reduced.

Method for disinfecting filtered water from water plant with cooperation between medium-pressure ultraviolet catalyzing peroxymonosulfate and chloramine

The invention discloses a method for disinfecting filtered water from a water plant with cooperation between medium-pressure ultraviolet catalyzing peroxymonosulfate and chloramines. The method includes following steps: adding peroxymonosulfate to outlet water from a water plant filtering tank to obtain a mixed solution with a concentration being 0.2-0.4 mmol/L through a tubular mixer; performing disinfection to the mixed solution in a medium-pressure ultraviolet disinfecting reactor, wherein an addition dosage of the medium-pressure ultraviolet is 10-20 mj/cm<2> and a disinfection time in the reactor is 5-10 min; and adding 0.3-0.4 mg/L chloramines to an end of the ultraviolet disinfecting reactor to complete the disinfection with cooperation between medium-pressure ultraviolet catalyzing peroxymonosulfate and chloramines. By means of the method, a cooperative effect of medium-pressure ultraviolet, peroxymonosulfate and chloramines fully works so that bacteria and microorganisms can be controlled in high efficiency and a reagent addition dosage and disinfection by-product can be reduced. Sustainability of disinfection and sterilization of water in a following water supply network can be ensured and drinking water safety can be ensured.

Photosensitizer-loaded soluble microneedle, photosensitizer-loaded soluble microneedle array and preparation method

ActiveCN111544758AImprove transdermal efficiencyEvenly distributedMicroneedlesMedical devicesLaser etchingPhotosens
The invention discloses a soluble microneedle loaded with a photosensitizer. The microneedle comprises an integrally formed base, a soluble polymer needle body positioned on the base and a needle tiploaded with the photosensitizer, the invention discloses a preparation method of a photosensitizer-loaded soluble microneedle array. The preparation method comprises the following steps: 1) preparinga polydimethylsiloxane (PDMS) mold plate; 2) carrying out laser etching on a polydimethylsiloxane (PDMS) micro-needle female die; 3) preparing a mixed solution containing a photosensitizer and a soluble polymer; (4) treating the female die obtained in the step (2) with oxygen plasma, coating the surface of the female die with the mixed solution obtained in the step (3), enabling the medicine to enter the tip end of the die in a vacuum environment, and recycling the redundant medicine; adding a soluble polymer solution to the mold, and filling the mold with the soluble polymer in vacuum; afterstanding, drying is performed, and then the polydimethylsiloxane (PDMS) microneedle array female mold is peeled off. According to the invention, the technical problem of unreasonable administration mode in photodynamic therapy can be solved, and the preparation problem of the photosensitizer-loaded soluble microneedle array is also solved.

Construction method of crack-resisting cement stabilized crushed stone base course

The invention discloses a construction method of a crack-resisting cement stabilized crushed stone base course. The problems that at present, contraction fissures of a traditional cement stabilized crushed stone are many, the surface is prone to loosening after freeze-thaw, the defects of the construction mode exist in the construction side, and therefore large-area cracks and freeze-thaw are generated in the subsequent process of the road surface are solved. According to the key points of the technical scheme, the construction method comprises the following steps that (a), the crack-resisting cement stabilized crushed stone base course comprises a collected material, 3%-5% of cement and water, the curve of the screen hole size of the collected material and the passing percentage is in an S shape; (b), a mixture is mixed; (c), the mixture is conveyed; (d), the mixture is paved, specifically, square timber cushion blocks are put under a paver screed plate in advance, and mixture paving adopts two pavers to synchronously operate in an echelon formation mode; (e), the mixture is grinded; and (f), curing is conducted, specifically, a curing film or geotechnical cloth is covered to conduct hydrating curing, so that the surface of the cement stabilized course keeps a moist state all the time, and the cement stabilized crushed stone base course with the crack-resisting property being obviously improved is obtained.
Owner:昆山市交通工程集团有限公司 +1

Application of metal derivative containing chlorophyll and hydrolyzate thereof as plant growth regulator

ActiveCN102273467AExcellent plant growth regulator activityReduced activityBiocidePlant growth regulatorsNon toxicityRoot growth
The invention provides an application of a metal derivative containing chlorophyll and hydrolyzate thereof as a plant growth regulator. The metal derivative containing chlorophyll and hydrolyzate thereof is selected from chlorophyll metal chelate, a chlorophyllin metal chelate and a monomeric metal chelate obtained by separating a chlorophyllin mixture. The chlorophyll is a green pigment extracted from a natural plant raw material and provided with a phaeophytin mother ring structure. The chlorophyllin is a mixture of multiple dihydroporphin components obtained by hydrolyzing the chlorophyll.The monomeric chlorophyllin component is selected from dihydroporphin-e4, dihydroporphin-e6 or phaeophorbide a monomethyl ester. Metal ions comprise bivalent or trivalent transition metal manganese, iron, copper or zinc ions in an oxidation state. The plant growth regulator provided by the invention has the advantages of safety, non-toxicity, low residue, strong activity, good effect, stable product property, controllable and reliable quality and easiness in promotion and application; the chlorophyll content of the plant can be increased, the root growth is promoted, the germination ratio is increased, the stress resistance is enhanced and the yield is also increased.

Polycarboxylate-based ceramic water reducer and preparation method as well as application thereof

The invention discloses a polycarboxylate-based ceramic water reducer and a preparation method as well as an application thereof. The water reducer comprises monomers, distilled water, an inorganic chain transfer agent and an initiator; the monomers account for 29-45 percent of the total mass of the monomer and the distilled water; the monomers comprise acrylic acid and crotonic acid; acrylic acid accounts for 66-89 percent of the total mass of the monomers, and crotonic acid accounts for 10-40 percent of the total mass of the monomers. The polycarboxylate-based water reducer based on crotonic acid has the advantages of low mixing amount, high water reducing rate, simplicity in preparation and operation and no need of compounding with inorganic salts, and meet the requirements of ceramic production enterprises; the requirements on equipment during the production of the polycarboxylate-based ceramic water reducer are simple, post treatment is unnecessary, the energy consumption is small, and no environmental pollution is generated; the dose of pottery clay is small during application, the water reducing effect is good, the fluidity of ceramic slurry can be remarkably improved, and the viscosity of ceramic slurry is reduced; no settlement phenomenon of ceramic slurry appears within the adding dose range.
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