1874results about How to "Small dose" patented technology

A medication dispensing apparatus having a gear set (64) to provide a mechanical advantage to the plunging of the apparatus plunger (66). The gear set (64) has a first pinion (114) in meshed engagement with a rack of the plunger (102), and a second pinion (126) in meshed engagement with a rack of a drive member (80) of the apparatus. The gear set (64) operatively interconnects the plunger (66) and the drive member (62) such that after the plunger (66) is moved relative to the housing in a proximal direction to prepare the apparatus for injection, the plunger (66), when manually pushed back toward the housing, causes the drive member (62) to advance in a distal direction to force medication through an outlet, typically provided with an injection needle, at the distal end of the apparatus.

A needle-less injector device for delivering a dose of fluid intradermally, subcutaneously or intramuscularly to an animal or human. The device includes an inner housing having opposed ends. A syringe is disposed in one end of the inner housing. The syringe includes a nozzle for delivering a dose of fluid held within the syringe. A plunger is movably disposed within the syringe. A spring powered hammer is movably disposed within the inner housing. The hammer cooperates with the plunger to drive the dose of medicament from the nozzle. An injection delivery spring for powering the hammer is positioned and compressed between the other end of the inner housing and the spring powered hammer. An outer housing slideably supports the inner housing. A skin tensioning spring is mounted between the inner housing and the outer housing, the skin tensioning spring biasing the nozzle of the syringe against the animal or human. A trigger mechanism is disposed in the outer housing, the trigger mechanism cooperating with the spring powered hammer to release the injection delivery spring, wherein the size of the injection delivery spring and the length of the hammer dictate the amount of dose delivered and whether the dose is delivered intradermally, subcutaneously or intramuscularly to an animal or human.

The present invention relates to a method capable of using natural and artificial synthetic isosulfocyanate compound or its derivative to prevent and cure prostatic diseases and skin carcinoma. The internal tests show that various isosulfocyanate compounds or their derivatives can induce prostatic cell II phase drug metabolic detoxication enzyme-glutathione transferase so as to can inhibit the hyperplasia of prostate and inflammation, and can prevent and cure prostatic carcinoma and skin carcinoma.

The invention discloses a standardized cultivation method of super double cropping rice. Currently, the super double cropping rice is cultivated still according to a traditional method for cultivating ordinary rice, yield is not stable, the quality is not high, and grain safety and income increasing of farmers are seriously affected. The standardized cultivation method includes the technical measures of selection of varieties, selection of environment of producing area, robust seedlings cultivation, field cultivation and management, integrated control over plant diseases and insect pests and the like, and systematized standardized cultivation technology integration research of the super double cropping rice is carried out. According to a test result after 56 thousand of hm2 is popularized and applied, the yield of 667 m<2> reaches 456.67 kg/ 667 m<2> averagely, the yield increase range reaches 42.57 kg/ 667m<2> averagely, the rate of growth reaches 10.27% averagely, the increased income of every 667 m<2> reaches 100.58 RMB/ 667 m<2> averagely, the cost for using chemical pesticide to control diseases, pests and the like is lowered, and the cost is saved by 6.5-7.2 RMB/ 667 m<2>. According to the technical standard, the production of the super rice is indexed and scientized, the technical operability is high, the application effect is good, the standardized cultivation method is deeply popular by mass farmers, and the gained economic benefit, social benefits and ecological benefits are remarkable.

This invention relates to a composition and method for treating diseases and disorders of the prostate such as prostatitis, benign prostatic hypertrophy, and prostate carcinoma. The prostate is treated by intraprostatic injection of a biodegradable sustained release formulation. By injecting the treatment substance directly into the prostate, improved treatment results are obtained with a much lower treatment substance dosage. Additionally, by incorporating the treatment substance into a biodegradable sustained release formulation, the need for frequent repetition of injections is eliminated.

The invention discloses a water soluble corrosion inhibitor, the preparation method and the application of the corrosion inhibitor, solving the defect of narrow application range of the corrosion inhibitor pH in the prior art; the water soluble corrosion inhibitor is composed of 20-70 weight proportion of imidazolines derivates, 1-10 weight proportion of pyridine derivates, 1-20 weight proportion of corrosion inhibition auxiliary agent and 10-50 weight proportion of solvent, based on the total weight of the corrosion inhibitor as the reference. The water soluble corrosion inhibitor in the invention has corrosion inhibition effect on the metal material in the medium with wide PH variation range (pH equals to 1-10) and good metal surface film formation property.

The invention belongs to the field of application of near-infrared laser, nuclear irradiation, electron and image rebuild in systematic biology and medicine. It is characterized in that high-specificity nuclear species and fluorescent probe are implanted in live animal to realize double mark of muscle deep layer or internal organ tumor cell. The emission signal of nuclear species is checked by sensitive electron-multiplier phototube in array copulation position of scintillation crystal; feeble fluorescent signal generated by visible light or infrared agitation is checked by high quantum yield CCD camera. The two checking systems are orthogonally arranged in the same surface, the live nuclear species and fluorescent signal can be checked simultaneously through rotary image cavity, and double module three dimensional tomography image of small animal can be rebuilt with software algorism. The invention is characterized by multi-image forming modules, abundant information and simple operation.

The invention pertains to a dosage form 10 and to administering an antidepressant medicament 16 for an extended period of time in a rate-known dose.

The invention relates to an implant having a base body, consisting completely or partially of a biocorrodible metallic material, such that it decomposes in an aqueous environment to form an alkaline product, and the base body has a coating or a cavity filling, comprising a polymer matrix and at least one drug embedded in the polymer matrix, characterized in that at least one polymer of the matrix and the at least one drug are coordinated so that the drug elution rate from the matrix is increased with an increase in pH.

The invention relates to an inhalation spray of antivirus medicines. The inhalation spray comprises the following components in percentage by mass of 0%-30% of antivirus activity agents, 0%-30% of auxiliary agents, 0%-30% of taste masking agents and the balance solvents, wherein the content of the antivirus activity agents and the content of the auxiliary agents are not 0% at the same time. Compared with the prior art, the inhalation spray disclosed by the application has the purpose that during outbreak period of epidemic corona viruses and other viruses, people do not need to occupy medicalresources in short supply and only need to inhale the antivirus medicines into respiratory tracts, medicine administration is accurately targeted, and the objective of preventing virus infection and propagation can be achieved; in addition, through united medication of the antivirus activity agents and the auxiliary agents, besides, various medicines are inhaled into the respiratory tract of a patient, synergistic treatment effects are generated, the viruses are eliminated, and serious respiratory tract and infection and serious pulmonary infection caused by the viruses can be treated; and chloroquine type antivirus medicines and macrocyclic antibiotics are inhaled through spraying for united medication, and the dosage of the medicines can be notably reduced, so that side effects of prolonged QT intervals, Tdp and sudden cardiac death caused by the medicines can be reduced.

An interleukin-15 (IL-15) gene modified natural killing cell strain for immunotherapy of tumor is prepared through inserting the cDNA coding region of IL-15 in pcDNA3 eucaryotic expression carrier, configuring secretion-type recombinant eucaryotic expression carrier pc DNA3/IL-15, using liposom to transfecte cell NK-92, adding Geneticin (G418) to screening culture medium, screening, limited dilution to cloned cells, detecting activity, choosing positive cell clones, and amplification.

The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.

The invention relates to fluoride-free low-acid zwitterion quartz sand reverse flotation process, which is characterized by comprising following steps: (1) pretreatment; (2) flotation: adjusting the pH (potential of hydrogen) value of ore pulp to 4-5 by sulfuric acid, performing air agitation, adding 40g/t-80g/t of positive ion collecting agent and 60g/t-75g/t of foaming agent, stirring and removing foams in primary flotation; and adjusting the pH value of the ore pulp to 9-10 by 200g/t-300g/t of sodium carbonate, performing air agitation, adding 80g/t-150g/t of negative ion collecting agent,then adding 60g/t-75g/t of foaming agent, stirring and removing foams in secondary floatation; and (3) washing ores in a flotation tank by water until the ores are neutral, and drying the ores to obtain quartz sand concentrates. The flotation collecting agents are fine in selectivity, the process is simple, cost is low, the purity of the quartz sand is high, the content of iron and aluminum impurities is low, and the problem that traditional fluoride and high-acid process damages equipment and environments is avoided in a flotation process.

The invention provides an enzyme preparation for degumming fresh ramie, a preparation method thereof and a method for degumming the fresh ramie. Alkaline pectinase and hemicellulase are mixed, and the obtained enzyme preparation can be directly used for the method for degumming the fresh ramie, so that the problem that the fresh ramie cannot be effectively degummed by a chemical degumming method and a biological bacterium degumming method is solved; meanwhile, the process for degumming the fresh ramie is simple, and preparation and enzyme immersion steps of the fresh ramie are performed in a farmland; the using amount of chemical medicaments in high-pressure cooking treatment fluid is small, and toxic chemicals are not used; and the chemical oxygen demand in wastewater obtained after ramie fibers are prepared is low, and the wastewater contains a large number of ions such as phosphorus, potassium, sodium and the like, so the wastewater can be directly used for irrigating the farmland, and the cost is saved and the environment is also protected.