40 results about "Egg drop syndrome" patented technology

The invention discloses an antibacterial antivirus Chinese medicinal composition for the animal, comprising the following main medicament ingredients: scutellaria extract, honeysuckle extract, isatis root extract and glycyrrhiza extract. the pharmaceutical composition of the invention can be made into premix, injection, oral liquid or granula, also can be made into feedstuff premix adding into the feedstuff. the chinese medicinal composition of the invention is a pure Chinese medicinal compound preparation which has the antibacterial, anti-inflammation, antivirus and immunity-reinforced functionsand wide application range, can effectively prevent and treat various livestock and poultry diseases caused by the virus and the bacteria, such as piggyyellow-white dysentery, swine plague, infectious pleuropneumonia, asthma, canker, circovirus, swine influenza, white diarrhea, newcastle disease, bursa of Fabricius, egg drop syndrome, duck serositis and the like, and has fast effect and remarkable curative effect.

The invention aims at providing an I-colony fowl adenovirus 4 strain, which is preserved with preservation number of CCTCC No. V201541. The I-colony fowl adenovirus 4 YBAV-4 strain disclosed by the invention is excellent in specificity and immunogenicity; a specific precipitation line does not appear in specific positive serum chicken SPF chicken serum such as infected cell sap and egg drop syndrome resisting virus, chicken infectious bursal disease virus, Newcastle disease virus, chicken infectious laryngotracheitis virus, chicken Marek's disease virus, avian influenza and the like, while an obvious specific precipitation line appears in I-colony fowl adenovirus 4 specific serum. The strain disclosed by the invention, as a vaccine strain which is good in manufacturing effect, is capable of preventing chicken hydropericardium syndrome, and the strain is applicable to identification of virus serotype and investigation on epidemiology.

The invention relates to a method for preparing a vaccine by breeding infectious bursal disease virus (IBDV) by a chicken embryo source cell line. The method mainly comprises the following steps of: 1) subculturing cells DF-1 for preparing vaccines; 2) breeding IBDV HQ cell seeds; 3) breeding virus liquid for preparing the vaccines; 4) concentrating and inactivating the virus liquid for preparingthe vaccine; 5) preparing other virus liquid of newcastle disease method, newcastle disease-infectious bronchitis virus method, and newcastle disease-infectious bronchitis virus-egg drop syndrome method combined vaccine and concentrating; and 6) proportioning inactivated combined vaccine, emulsifying and sub-packaging. The production process is simple, and stable and is easy to operate, eliminates biological potential safety hazard existing in the conventional vaccine production, and overcomes the defects that large-scale production of the vaccines is limited by supply of chicken embryos; cost and batch-to-batch variation are reduced; the virus titer and the quality of vaccine are improved; basis is laid for culturing virus liquid on large scale by a suspension culture technology in vaccine industry; and the produced IBDV inactivated vaccine and combined vaccine have high safety and immune efficacy, and have the complete immune protection effect on IBDV attack.

The invention is concerned with a kind of preparation method of inactivated vaccine to prevent new castle disease, infectious bronchitis and egg drop syndrome vaccine. The selected genus is Newcastle Disease virus La Sota individual plant, infectious bronchitis virus M41 individual plant, HN99 kidney type of aberrance individual plant and EDS76 Jing 911 individual plant. Dilute three kinds of virus and inoculate in the allantoic cavity of SPF chick embryo and affectable duck embryo. Collect liquid of embryo to alive and dead embryos as seed. Dilute and inoculate in allantoic cavity of affectable chick embryo or duck embryo to get liquid of virus embryo. Concentrate with equipment and add with formaldehyde solution to prepare bacterin through emulsion process. This invention can prevent Newcastle Disease, chick kidney type and breathing type infectious bronchitis, and egg drop syndrome vaccine. It can reduce the times of injection and the cost of epidemic prevention for easy using and practicality.

The invention relates to veterinary herbal medicine capable of increasing the egg yield of laying hens. The veterinary herbal medicine is prepared from, by weight, 6-12 parts of codonopsis pilosula, 6-12 parts of astragalus membranaceus, 6-12 parts of herba epimedii, 15-36 parts of folium artemisiae argyi, 15-36 parts of leonurus, 15-36 parts of hawthorn fruit, 15-24 parts of euphorbia humifusa, 15-24 parts of fructus psoraleae, 30-60 parts of pine needles, 15-24 parts of rhizoma atractylodis, 6-12 parts of angelica sinensis, 15-36 parts of houttuynia cordata, 15-36 parts of malt, 6-15 parts of poria cocos, 6-15 parts of rhizome atractylodis macrocephalae, 6-15 parts of cistanche, 6-12 parts of salviae miltiorrhizae, 6-12 parts of silkworm excrement and 15-36 parts of pericarpium citri reticulatae. By invigorating spleen-stomach, replenishing qi, tonifying spleen, reinforcing kidney and invigorating blood circulation, the productivity of laying eggs is improved, egg quality is improved, disease resistance is improved, and feed return rate is increased. Meanwhile, the veterinary herbal medicine can be used for preventing and treating the egg drop syndrome, laying drop caused by unknown reasons, and no laying peak or laying lingering without increase of laying hens, and has a remarkable effect on recovery of the egg laying rate of sick hens after rehabilitation.

In the invention, a section of conserved sequences of four virus genes, namely Newcastle disease virus (NDV), infectious bronchitis virus (IBV), polymerase chain reaction (PCR) technology amplified egg drop syndrome (EDS) and infectious laryngotracheitis (ILT) by a molecular biotechnology (RT) PCR method is taken as a probe, a cellulose membrane is taken as a substrate (namely a most important basic platform in the detecting kit) to extract target pathogenic nucleic acid from pathological materials, and marked bio-16-dUTP is added during (RT) PCR to obtain a marked PCR product. The marked product is placed in the detecting kit for hybridizing detection, and quick and effective judgment and analysis on a biological sample are realized by observing changes of hybridization colors.

The invention discloses an mRT-PCR (multiple reverse transcription-polymerase chain reaction) kit for discriminating and detecting important avian economic animal viruses and an application of the mRT-PCR kit. The kit comprises primer pairs for detecting an AIV (avian influenza virus) M gene, AIV H7,H9 and H5 subtypes, an NDV (newcastle disease virus), an ILTV (infectious laryngotracheitis virus), an IBDV (infectious bursal disease virus) and an EDS (egg drop syndrome) virus. The mRT-PCR kit has the characteristics of high sensitivity, high specificity and the like when used for detecting AIVs and other common respiratory viruses, can be used for immediately detecting and discriminating important and popular subtypes of the AIVs and five avian respiratory pathogens most popular in China and has a great significance in zoonosis control, monitoring, prevention and control of avian mixed infection, biosafety of farms, reduction of loss of the breeding industry, food safety, quarantine and the like.

The invention discloses an antibacterial antivirus Chinese medicinal composition for the animal, comprising the following main medicament ingredients: scutellaria extract, honeysuckle extract, isatis root extract and glycyrrhiza extract. the pharmaceutical composition of the invention can be made into premix, injection, oral liquid or granula, also can be made into feedstuff premix adding into thefeedstuff. the chinese medicinal composition of the invention is a pure Chinese medicinal compound preparation which has the antibacterial, anti-inflammation, antivirus and immunity-reinforced functionsand wide application range, can effectively prevent and treat various livestock and poultry diseases caused by the virus and the bacteria, such as piggyyellow-white dysentery, swine plague, infectious pleuropneumonia, asthma, canker, circovirus, swine influenza, white diarrhea, newcastle disease, bursa of Fabricius, egg drop syndrome, duck serositis and the like, and has fast effect and remarkable curative effect.

The invention discloses a feed preventing egg drop syndrome of a laying duck. The feed comprises the following components in parts by weight: 15 to 35 parts of corns, 15 to 35 parts of sorghum, 8 to 15 parts of flour, 8 to 20 parts of soybean meal, 3 to 10 parts of rapeseed meal, 8 to 20 parts of corn distiller, 8 to 10 parts of rock flour, 2 parts of Chinese herbal medicine preparation, 0.2 part of a micro ecological preparation and 2 to 2.5 parts of multi-dimensional multi-mineral premix compound. The feed is rich in nutrition, the growth need of the laying duck can be comprehensively satisfied; by supplementing the Chinese herbal medicine and the micro ecological preparation, the anti-virus capability of the laying duck can be effectively improved, and the growth performance, the egg laying rate and the egg quality of the laying duck can be improved; moreover, the feed is environmentally friendly, safe, non-toxic and free from side effect and residue.

The invention discloses a traditional Chinese medicine particle for preventing and treating avian influenza and improving chicken flock immunity and a preparation method thereof. The traditional Chinese medicine particle is prepared from an echinacea extract, a lonicera japonica leaf extract and an astragalus membranaceus extract in a mixing manner. The traditional Chinese medicine for preventing and treating the avian influenza and improving the chicken flock immunity disclosed by the invention is reasonable in chosen drugs, and quick to take effect, can prevent and treat the avian influenza, also improves the immune condition of the chicken flock, enhances the antiviral ability of a body, enables the chicken to freely intake, prevents an egg drop caused by an egg drop syndrome, and simultaneously has the advantages of being small in side effect, low in cost, high in drug stability and the like. The traditional Chinese medicine particle is simple and efficient in technology and easy to operate. The proposed traditional Chinese medicine for preventing and treating the avian influenza and improving the chicken flock immunity is applied to prevention and treatment of the avian influenza, and significant improvement of the chicken flock immunity.

The invention relates to a heat-clearing powder for treating low egg-laying syndrome in summer and its preparing process, which is prepared from the following constituents (by weight portions) through mixing homogeneously: dyers woad leaf 48-72g, radix isatidis 48-72g, calcium sulphate 48-72g, rhubarb horsetails 24-36g, compound of glauber-salt and liquorice 24-36g. The preparing process consists of disintegrating the raw materials, passing through 20-80 mesh sieves, and mixing homogeneously.

The invention discloses a traditional Chinese medicine composition for preventing laying-hen egg drop syndrome and a preparation method. The traditional Chinese medicine composition is prepared from the following the components of radix scutellariae, cortex phellodendri, herba andrographis, fructus gardenia, radix sophorae flavescentis, radix glycyrrhizae, medicated leaven, pine needle, radix astragali, herba epimedii, herba leonuri and fructus crataegi. According to the traditional Chinese medicine composition, the laying-hen egg drop syndrome can be effectively prevented, the toxic and sideeffect is small, the traditional Chinese medicine composition takes effect quickly, immunity of a hen body can be improved, the laying rate of a laying-hen is improved, and the number of sand-shell eggs, white-shell eggs, thin-shell eggs, broken-shell eggs and soft-shell eggs is reduced. At the same time, raw materials of the traditional Chinese medicine composition has wide sources, the cost is low, safety is high, and the traditional Chinese medicine composition has the characteristics of no-toxic-side effects, no pollution, no residue and no production of medicine resistance.

The invention provides a Chinese herbal medicine additive for a laying hen feed. The Chinese herbal medicine additive is composed of the following raw materials in parts by weight: 80 to 120 parts ofpolygonum cuspidatum, 50 to 100 parts of red sage root, 50 to 100 parts of semen cuscutae, 50 to 100 parts of Chinese angelica, 50 to 100 parts of ligusticum wallichii, 50 to 100 parts of oyster, 30 to 100 parts of garden burnet, 50 to 100 parts of cistanche, 10 to 50 parts of clove, and 30 to 100 parts of white peony root. The granularity of raw materials is 100-200 meshes. 10 grams of Chinese herbal medicine additive is added into each one kilogram of laying hen feed and evenly mixed, and laying hens can eat the feed freely. The Chinese herbal medicine additive has the functions of promotingblood circulation to remove blood stasis, boosting essence, tonifying the kidney, nourishing yin, and dissipating binds, can effectively prevent decreasing laying rate caused by salpingitis of layinghens, egg drop syndrome, and weak physique of laying hens, and is capable of improving the uniformity of laying peak periods, yield rate, physique, immunity, and disease resistant performance of laying hens.

The invention discloses a compound propolis composition for treating the livestock egg drop syndrome and a preparation method thereof, relating to the field of animal medicine. The preparation method of the composition comprises the following steps of: (1) performing ultrafine pulverizing on various components (excluding interferon) in a formula respectively, and sieving with a 700-mesh sieve; (2) weighing 15-35 parts by weight of propolis, 5-15 parts by weight of chicken interferon and 10-30 parts by weight of astragalus, and mixing for 5-10 minutes to uniform state; (3) weighing 10-25 partsby weight of dangshen, 10-35 parts by weight of honeysuckle flower, 10-25 parts by weight of malaytea scurfpea fruit and 15-35 parts by weight of isatis root, and mixing for 5-10 minutes to uniform state; and (4) combining the compositions obtained in the steps (2) and (3), and continually mixing for 10-15 minutes to uniform state. The compound propolis composition has the beneficial effects of reasonable formula, easiness for preparing, no toxic or side effect, environmental friendliness, no medicament residue, no medicament tolerance, ultrafine pulverizing, high bioavailability, very remarkable curative effect and specially good treatment effect on the livestock egg drop syndrome as proved by clinical application.

The present invention is intended to provide an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. The EDS vaccine provided to this end contains as an active ingredient fused protein in which a polypeptide having a coiled-coil forming unit is bound to the knob region in the fiber protein of EDS virus (EDSV).

The invention discloses a traditional Chinese medicine feed additive for preventing egg drop syndrome, a preparation method and application. The feed additive comprises the following materials in parts by weight: 60-80 parts of orange peel, 30-50 parts of hawthorn, 30-50 parts of codonopsis pilosula, 20-50 parts of folium isatidis, 20-40 parts of phellodendron amurense, 20-40 parts of astragalus , 25-40 parts of leonurus, 25-40 parts of dandelion, 20-30 parts of honeysuckle, 15-30 parts of Rehmannia glutinosa and 15-30 parts of mangnolia officinalis. The traditional Chinese medicine additive disclosed in the invention is a pure traditional Chinese medicine preparation without toxic or side effect and drug residue. By adopting the traditional Chinese medicine feed additive, the egg laying performance of laying hens can be improved, the income can be increased, the quality of egg shells can be improved, the egg breaking rate is reduced, and the purpose of increasing yield and income is achieved.

The invention discloses a tetragenous egg yolk antibody oral liquid and a preparation method for the same. The tetragenous egg yolk antibody oral liquid comprises the following raw materials in part by volume: 95 to 105 parts of whole egg aqueous solution containing tetragenous egg yolk antibodies to newcastledisease, infectious bronchitis, egg drop syndrome and avian influenza, 0.2 to 0.3 part of caprylic acid, 0.2 to 0.3 part of formaldehyde and 0.01 to 0.02 part of thiomersal, and each milliliter of the oral liquid further comprises 800 to 1,000 units of mycillin. The tetragenous egg yolk antibody oral liquid prepared by the method is low in production loss, high in bioactivity and free of clinical side effects, and contains multiple highly-effective immunoreactive substances; meanwhile, the tetragenous egg yolk antibody oral liquid contains various proteins in egg white, so that adverse effects on the antibodies when the tetragenous egg yolk antibody oral liquid is orally taken can be reduced.

The invention discloses a traditional Chinese medicine premix for prevention and treatment of an egg drop syndrome of laying hens and a preparation method of the traditional Chinese medicine premix. The premix is prepared from, by weight, 8-12 parts of semen cuscutae, 6-10 parts of herba lycopi, 3-6 parts of herba bidentis frondosae, 5-8 parts of spica prunellae, 10-15 parts of rhizoma cibotii, 3-6 parts of herba portulacae, 8-10 parts of semen glycines nigrae, 6-10 parts of fructus cnidii, 2-5 parts of spora lygodii, 4-8 parts of fructus chaenomelis, 2-5 parts of herba solani, 3-8 parts of excrementum pteropi and 5-8 parts of fructus foeniculi. According to traditional theories and treatment principles in traditional Chinese medicine, physiological characteristics of the laying hens and clinical symptoms of the egg drop syndrome, the premix for prevention and treatment of the egg drop syndrome is developed. The traditional Chinese medicine premix is scientific and compatible in formula and synergistic in efficacy and has efficacies of kidney warming, Yang tonifying, kidney essence nourishing, Qi replenishing, blood nourishing, blood circulation promoting, stasis removing, heat clearing, detoxifying, wind dispelling, dampness eliminating, spleen strengthening, stomach harmonizing, Qi circulation promoting and pain relieving, and effectiveness in prevention and treatment of the egg drop syndrome of the laying hens can be achieved. In addition, the traditional Chinese medicine premix is extensive in traditional Chinese medicine source, effective, safe and reliable and has no side effect.

The invention provides traditional Chinese medicine oral liquid for preventing the egg drop syndrome and a preparation method thereof. The traditional Chinese medicine oral liquid consists of the following components in parts by weight: 2-4 parts of radix scutellariae, 3-6 parts of flos lonicerae, 1-2 parts of folium isatidis, 2-4 parts of fructus forsythiae, 2-4 parts of rhizoma coptidis, 1-2 parts of cortex phellodendri, 1-2 parts of radix codonopsis, 1-2 parts of radix astragali and 1-2 parts of liquorice. The traditional Chinese medicine oral liquid is prepared by a decocting method. In the traditional Chinese medicine oral liquid for preventing the egg drop syndrome, the traditional Chinese medicines are reasonably organized, and an effective treatment medicine for preventing the egg drop syndrome is provided for the poultry industry. The traditional Chinese medicine oral liquid takes an effect quickly, realizes an exact curative effect, prevents residues and any toxic side effect, and does not generate drug resistance easily, thereby being the first choice for treating the egg drop syndrome. The preparation method is simple and is suitable for large-scale industrial production.

The invention discloses a preparation and activity detection method for duck leukocyte interferon for treating duck viral disease. Duck source newcastle disease virus is used as an inducer for inducing healthy duck leukocyte. The method comprises the processes of raw material preparation, mixing, water bath stirring culture, centrifugation and harvesting, virus inactivation, sterilization, anti-virus activity detection and the like. The fresh complete blood of a duck is successfully used as a raw material, the preparation process is simple and convenient, and the product quality is reliable. After the duck leukocyte interferon is used for a duck body, the duck leukocyte interferon has the characteristics of good treatment effect, safety, reliability, no toxic or side effect and the like. The duck leukocyte interferon for broad spectrum virus resistance has the function of treating the viral diseases such as duck plague, duck viral hepatitis, duck source newcastle disease, duck source egg drop syndrome and the like. The duck leukocyte interferon is used for the animal body, and has the advantages of good treatment effect, safety, reliability, low using amount, no toxic or side effect, low cost and the like.

The invention relates to a traditional Chinese medicine granule for preventing and treating a chicken egg drop syndrome. The traditional Chinese medicine granule comprises acanthopanax root, fiveleaf gynostemma herb, rhizoma alismatis, herba epimedii and chinese fevervine herb. According to the traditional Chinese medicine granule disclosed by the invention, the components are weighed according to measurement and decocted twice in water; the filtrates obtained by the two times of decoction are combined, decompressed and concentrated; a dried product is added with cane sugar for granulation; and granules are sieved, dried again and then sieved to obtain a finished product. Effective components of each traditional Chinese medicine are extracted and matched with one another to co-act; when used, the traditional Chinese medicine granule is mixed with water according to a certain ratio, the egg yield and egg quality of egg chickens can be recovered after sick chickens continuously take the traditional Chinese medicine granules for 5 days, the egg shells are normal in color, and no soft-shell eggs and deformed eggs are produced.

The invention discloses laying hen feedstuff used for treating a laying hen egg drop syndrome and a preparation method thereof. The feedstuff is prepared from corn, bean pulp, peanuts, sunflower seeds, cabbage, black sesame, limestone powder, edible salt, butter, microelement premix, vitamin premix and a feedstuff additive. The feedstuff has the advantages that the raw materials of the laying hen feedstuff are natural products and can effectively prevent the laying hen egg drop syndrome and increase the quantity of eggs laid by laying hens and the qualified rate of immunity, and the feedstuff is high in safety and free of medicine residues and toxic and side effects.

The invention relates to a traditional Chinese medicine for preventing and treating the egg drop syndrome of laying hens. According to the traditional Chinese medicine, the stress risk in a vaccine injection process can be effectively solved, and the problems of drug residue and body injury can be effectively solved. According to the technical scheme adopted for solving the technical problems, thetraditional Chinese medicine is prepared from following raw materials in parts by weight: 90g-100g of radix astragali, 60g-70g of herba leonuri, 30g-40g of angelica, 60g-70g of rhizoma chuanxiong, 60g-70g of radix cyathulae, 40g-50g of radix paeoniae rubra, 30g-40g of radix aucklandiae, 30g-40g of fructus amomi, 60g-70g of herba epimedii and 30g-40g of radix dipsaci. The traditional Chinese medicine is prepared by the steps of uniformly mixing the raw material drugs, crushing, sieving by virtue of an 80-100-mesh sieve so as to obtain powder, and carrying out subpackaging. The traditional Chinese medicine has a strict formula and a reliable treatment effect, does not have antibiont residue and is easy and convenient to use and easy to operate, the egg drop syndrome of the laying hens can be effectively prevented and treated, the use effect is good, and the traditional Chinese medicine is an innovation on the drug for treating the egg drop syndrome of the laying hens.

The invention provides a breeding method for improving winter spotted-brown chicken laying rate. The method comprises the steps that a water drinking inoculation method is adopted to inoculate spotted-brown chickens against fabricius bursa in the chick stage of the spotted-brown chickens to prevent epidemic situation, egg drop syndrome vaccine is injected into the spotted-brown chickens when the spotted-brown chickens are with the age of 125-130 days, and avian influenza vaccine is injected into the spotted-brown chickens when the spotted-brown chickens are with the age of 135-140 days. Sterilization solution is sprayed in a chicken house, the chicken house remains unchanged for 3-5 days, a sterilizing cushioning material is laid on the internal ground of the chicken house, and deodorizingand ammonia reduction cushioning materials with deodorizing and ammonia reduction effects are laid in the chicken house. The method has the advantages that the steps are simple, the operation steps are simple, convenience is provided for growers, the disease rate of the spotted-brown chickens is reduced, laying stopping of the spotted-brown chickens can be prevented, the egg laying amount of thespotted-brown chickens in winter is higher, and the income of the growers is improved.

The invention discloses a mixed freeze-dried powder for resisting Newcastle disease, infectious bronchitis, egg drop syndrome and bird flu and a preparation method thereof. The mixed freeze-dried powder comprises the following components: resisting Newcastle disease, infectious bronchitis, egg drop Syndrome, avian influenza quadruple yolk antibody, anti-Newcastle disease, infectious bronchitis, egg drop syndrome, avian influenza quadruple transfer factor, preservatives, inactivators, selenium, vitamin C, polyvinylpyrrolidone, glycine. In the mixed freeze-dried powder of the present invention, quadruple yolk antibody and quadruple transfer factor are compounded, supplemented with various auxiliary materials, and each component cooperates and coordinates with each other, which can significantly improve its comprehensive prevention and treatment of Newcastle disease and infectious bronchitis. , Egg Drop Syndrome, and Avian Influenza. It has the advantages of long storage time at room temperature, high antibody titer, and good biological activity. It is a powerful biological agent with broad application prospects.

The invention discloses a feedstuff additive used for treating a laying hen egg drop syndrome and a preparation method thereof. The feedstuff additive is prepared from coriolus versicolor, officinal magnolia bark, Chinese wolfberry fruits, Chinese dodder seeds, orobanche coerulescens, royal jelly, korshinsk peashrub and lotus root starch. The feedstuff additive has the advantages that the raw materials of the feedstuff additive are natural products, and can effectively prevent the laying hen egg drop syndrome and increase the quantity of eggs laid by laying hens and is high in safety and free of medicine residues and toxic and side effects.

The invention discloses a traditional Chinese medicine particle for preventing and treating avian influenza and improving chicken flock immunity and a preparation method thereof. The traditional Chinese medicine particle is prepared from an echinacea extract, a lonicera japonica leaf extract and an astragalus membranaceus extract in a mixing manner. The traditional Chinese medicine for preventing and treating the avian influenza and improving the chicken flock immunity disclosed by the invention is reasonable in chosen drugs, and quick to take effect, can prevent and treat the avian influenza, also improves the immune condition of the chicken flock, enhances the antiviral ability of a body, enables the chicken to freely intake, prevents an egg drop caused by an egg drop syndrome, and simultaneously has the advantages of being small in side effect, low in cost, high in drug stability and the like. The traditional Chinese medicine particle is simple and efficient in technology and easy to operate. The proposed traditional Chinese medicine for preventing and treating the avian influenza and improving the chicken flock immunity is applied to prevention and treatment of the avian influenza, and significant improvement of the chicken flock immunity.

The present invention is intended to provide an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. The EDS vaccine provided to this end contains as an active ingredient fused protein in which a polypeptide having a coiled-coil forming unit is bound to the knob region in the fiber protein of EDS virus (EDSV).

The invention discloses a traditional Chinese medicinal granule used for treating egg drop syndrome and a preparation method thereof and belongs to the filed of traditional Chinese herbal pharmaceutical preparation with uncertain structure. The traditional Chinese medicinal granule used for treating the egg drop syndrome is mainly prepared from the following raw materials in parts by weight: 5-8 parts of acanthopanax root, 4-6 parts of gynostemma pentaphyllum, 4-6 parts of rhizoma alismatis, 2-5 parts of epimedium herb and 1-3 parts of fevervine. The preparation method of the traditional Chinese medicinal granule used for treating the egg drop syndrome comprises the following steps: adding water into the seven traditional Chinese medicines, decocting, filtering decoction solution, concentrating into extract, drying, smashing, then adding cane sugar, blending, granulating, sieving granules with a 10-mesh sieve, drying, and then sieving with the 10-mesh sieve, thus the traditional Chinese medicinal granule is obtained. The traditional Chinese medicinal granule used for treating the egg drop syndrome is obvious in treatment effect, effect can be quickly taken, no drug residue is produced, no toxic or side effect is produced, and the traditional Chinese medicinal granule has a good application prospect in the feeding industry.

The invention discloses a traditional Chinese medicine compound preparation for preventing and treating egg drop syndromes. The traditional Chinese medicine compound preparation is prepared from the following raw material medicines in parts by weight: 50-200g of coptis chinensis, 75-300g of scutellaria baicalensis, 75-300g of folium isatidis, 75-300g of leonurus, 75-300g of angelica sinensis, 50-200g of hawthorn fruit, 50-200g of propolis, 10-50g of soy isoflavone and 100-400mg of vitamin E. The invention further discloses a preparation method of the traditional Chinese medicine compound preparation.