93 results about "Control diseases" patented technology

The invention relates to the technical field of microorganisms and bio-organic fertilizers, and particularly discloses a bio-organic fertilizer for preventing and treating rhizome diseases of horseradish and application of the bio-organic fertilizer, the bio-organic fertilizer comprises the following components: component A: a bacillus velezensis microbial inoculum with the preservation number of CCTCC NO: M 2022923 and a trichoderma yunnanense microbial inoculum with the preservation number of CCTCC NO: M 2025645; the component B is prepared from soybean meal, vinegar residues, charcoal, wollastonite powder and allicin. The biological organic fertilizer disclosed by the invention can be used for increasing the content of growth hormones such as salicylic acid (SA), jasmonic acid (JA) and ethylene (ET) and phytoalexin as well as the activity of chitinase and beta-1, 3-glucanase of a wasabi root system, and has a relatively good prevention and treatment effect on a black heart disease caused by infection of phoma wabi Yokog and a soft rot disease caused by infection of pectobacterium carotovorum subsp. Carotovorum (Pcc). The biological organic fertilizer disclosed by the invention has a relatively good prevention and treatment effect on the soft rot disease caused by infection of the phoma wabi Yokog and a relatively good prevention and treatment effect on the soft rot disease caused by infection of the phoma wabi subsp. Carotovorum (Pcc).

The invention relates to an active oxygen responsive triptolide prodrug immunoregulation hydrogel preparation as well as a preparation method and application thereof. Triptolide is coupled with an active oxygen responsive group to synthesize a triptolide derivative; then, the triptolide derivative is coupled with polypeptide, and a polypeptide-reactive oxygen responsive group-triptolide conjugate is obtained; then dissolving the polypeptide-active oxygen responsive group-triptolide conjugate in a solvent, standing, and carrying out self-assembly to obtain a triptolide prodrug nanofiber solution; finally, an immunomodulator is added into the triptolide prodrug nanofiber solution for incubation, and the active oxygen responsive triptolide prodrug immunoregulation hydrogel preparation is obtained. The hydrogel preparation disclosed by the invention can responsively release the medicine triptolide and the immunomodulator at the focus part of rheumatoid arthritis, so that the medicine accumulation of non-target organs is reduced, the safety and effectiveness of treatment are improved, and the progress of diseases is effectively controlled.

The invention, which relates to the health management field, discloses a health management service system comprising a data acquisition module, an analysis and evaluation module, a health management scheme making module and a health monitoring and early warning module. The data acquisition module is used for acquiring data of the medical detection equipment and the wearable health monitoring equipment and acquiring environmental data; the analysis and evaluation module is used for carrying out deep analysis and evaluation on the collected data; and the health management scheme making module is used for making a health management scheme according to the analyzed and evaluated result. The limitation that a traditional health management mode only depends on single data and lacks multi-dimensional comprehensive analysis is overcome, comprehensive and accurate control over personal or group health conditions is achieved by integrating data from multiple sources and covering medical detection, wearable device monitoring, environment data and the like, and the health management system is suitable for being popularized and applied. Real personalized and precise health management services can be provided, occurrence and development of diseases are effectively prevented and controlled, and life quality is improved.

The invention belongs to the technical field of microorganisms and biological control, and particularly relates to paenibacillus polymyxa and application thereof in biocontrol and growth promotion. Specifically, a strain of paenibacillus polymyxa GLZ219 is obtained through screening, and experiments prove that the paenibacillus polymyxa GLZ219 has a relatively high bacteriostasis rate on pathogenic bacteria of tomato neck and root rot; meanwhile, the strain has a good antagonistic effect on nine common plant pathogens such as Rhizoctonia solani and the like, and can be widely applied to green prevention and control of various crop diseases. Besides, the paenibacillus polymyxa GLZ219 has nitrogen fixing and potassium dissolving capabilities, can secrete heteroauxin and siderophores, and can effectively promote the growth of tomato plants, the plant height of tomato seedlings treated by fermentation liquor of the paenibacillus polymyxa GLZ219 is remarkably increased, diseases can be prevented and controlled, the growth vigor of crops can be improved, the yield and quality of the crops can be improved, and the paenibacillus polymyxa GLZ219 has a wide application prospect.

Embodiments of the present invention relate to mechanically-activated microcapsules (MAMCs) for controlled drug-delivery, wherein the MAMCs release one or more active ingredients in response to mechanical stimuli in a subject's body. The MAMCs provide a platform for stimulating biological regeneration, biological repair, modifying disease, and / or controlling disease in mechanically-loaded musculoskeletal tissues.

The invention discloses an unmanned aerial vehicle accurate spraying pest control system, which comprises an unmanned aerial vehicle, a spraying module, a sensor module, a data processing module and a control module, and is characterized in that the spraying module, the sensor module, the data processing module and the control module are all mounted on the unmanned aerial vehicle; the sensor module is electrically connected with the data processing module and transmits collected data to the data processing module, the data processing module is electrically connected with the control module and issues a control strategy to the control module, and the control module is electrically connected with the unmanned aerial vehicle and the spraying module and executes the control strategy. Through the integrated unmanned aerial vehicle system, precise recognition and treatment of diseases and insect pests can be achieved, pesticide use is reduced, environmental pollution is reduced, and meanwhile the crop yield and quality are improved.

Provided are methods for treating pemphigus using an FcRn antagonist such as efgartigimod. The methods of the invention provide a rapid onset of action to enable early disease control and maintenance of clinical remission, with or without a minimal dose of corticosteroids.

The agriculture and forestry fruit tree pest control device comprises a placing plate and wheels, the outlet end of a water pump is communicated with a liquid conveying pipe, the other end of the liquid conveying pipe is communicated with a pesticide spraying rod, one end of the pesticide spraying rod is communicated with a spraying head, and a valve is arranged on the outer side of one end of the spraying head. When branches and leaves at the top end of the climbing frame need to be sprayed with pesticide, an electric telescopic rod drives a pesticide spraying rod to rotate around one end of a supporting seat, so that the pesticide spraying rod is in a vertical state, then a second motor drives a screw rod to spirally rotate on the inner side of a moving plate, and the moving plate drives the pesticide spraying rod to move upwards through the supporting seat; a pesticide spraying rod penetrates through a gap in the inner side of the climbing frame to move to the position above branches and leaves at the top end of the climbing frame, then an electric telescopic rod drives the pesticide spraying rod to be in a horizontal state, and then a water pump can spray pesticide liquid on the inner side of a pesticide storage box to the branches and leaves at the top end of the climbing frame through the pesticide spraying rod and a spray head through a liquid conveying pipe. Therefore, the branches and leaves at the top end of the climbing frame can be conveniently sprayed.

Provided herein are compounds of Formula (I): (I), or a pharmaceutically acceptable salt or composition thereof, which are useful in the treatment or management of diseases or disorders mediated by AAK1 activity, muscle diseases and disorders, and other conditions.

The invention relates to the technical field of forestry, in particular to a pest control device for forestry trees. The device comprises a supporting plate, a guide rail and a prevention and treatment assembly, the guide rail is fixed to the supporting plate, the prevention and treatment assembly is slidably connected with the guide rail, the prevention and treatment assembly comprises a root prevention and treatment module, a stem prevention and treatment module and a leaf prevention and treatment module, and the root prevention and treatment module, the stem prevention and treatment module and the leaf prevention and treatment module sequentially sleeve the guide rail from bottom to top. The device is provided with the special prevention and control modules according to the characteristics of different parts of roots, stems and leaves of trees, accurate pest prevention and control can be achieved, and the prevention and control effect is improved. By means of different pesticide application modes such as drilling injection of roots, microneedle injection of stems and atomization spraying of leaves, pesticide can accurately act on pest and disease damage occurring positions, and waste of the pesticide is reduced.

The invention relates to application of a moxibustion transdermal component citral in regulation and control of synovial fibroblast-like cell (FLS) proliferation and inflammatory factor secretion, and belongs to the technical field of medicines. In the background technology, rheumatoid arthritis (RA) treatment depends on drugs, but has the defects of great side effects, easy recurrence and the like. It is found through experiments that within the concentration range of 0.131-13.1 [mu] M, citral can effectively inhibit FLS proliferation and regulate secretion of inflammatory factors IL-6 and TNF-alpha. The invention provides a safe and effective replacement therapy, and citral is used for regulating and controlling the FLS function so as to control the progress of RA disease and improve the joint function and life quality of a patient. The method has the advantages of high safety, low cost, multi-target effect and remarkable innovativeness and practicability.

The invention relates to a composition for preventing and treating plant diseases and application thereof, and belongs to the technical field of disease and pest control. The invention provides a composition for preventing and treating plant diseases. The composition is prepared from the following components in parts by mass: 5 to 15 parts of eugenol, 1 to 10 parts of fructus psoraleae extract, 2 to 8 parts of litsea cubeba extract and 6 to 12 parts of kasugamycin. According to the scheme, the components of the composition have a synergistic effect and have a remarkable bactericidal effect on various plant disease pathogenic bacteria, the prepared preparation has a good control effect on plant diseases and can control disease indexes, the dosage of the preparation is remarkably reduced compared with that of a conventional agent, and the cost of disease and pest control is greatly saved.

The application discloses a primer, a probe composition for nontuberculous mycobacteria typing and application thereof, and provides a PCR primer and a probe for rapid detection and typing of 13 common NTM in clinic based on genome big data for carrying out pan-genomics analysis, and the specific genes of the common NTM in clinic are screened by using a pan-genomics method, and then typing primers and probes are designed based on the genes, so that the problems of insufficient accuracy and specificity in NTM typing are solved; the various NTM specific sequences screened guarantee the accuracy and specificity; the high sensitivity of the PCR method and the specificity of the sequences guarantee that various interference substances in the clinical samples can be avoided, and the clinical samples can be directly analyzed; the PCR detection is low in cost and low in equipment requirement, and can be carried out in primary hospitals, thereby providing an efficient and economical solution for the precise diagnosis of nontuberculous mycobacteria, the control of disease prevalence and the large-scale disease screening.

The invention discloses a comprehensive prevention and control method for tobacco pepper vein mottle virus disease, which comprises the following steps: S1, optimizing agricultural layout and preparing a field parcel: selecting an area far away from a vegetable field, a curing barn and an airing shed as a seedling raising and planting field, removing weeds in the seedling raising and planting field, then intercropping gramineous crops, and deeply ploughing and sunning upturned soil before winter; s2, prevention and control management in a seedling raising period: detecting pathogens, preventing and controlling diseases and pests, and managing, cleaning and disinfecting facilities; the application not only pays attention to reasonable use of pesticides, but also combines physical prevention and control (such as covering an insect-proof net), biological prevention and control and agricultural management (such as crop rotation and weed removal) to form a comprehensive prevention and control system; the virus resistance of the tobacco can be effectively improved, and meanwhile, the influence on the environment is reduced; aphidius avenae is used for biological control, biological insecticides (such as sophocarpidine and azadirachtin) are released to be alternately used with chemical agents, natural enemies are effectively utilized for pest control, and use of the chemical agents is reduced.

The invention discloses a method for effectively preventing and treating damping-off of radix pseudostellariae. The method is a method for comprehensively preventing and treating damping-off of radix pseudostellariae by combining medicaments with agricultural measures. The prevention and control method mainly comprises the following steps: 1) soil improvement: improving the soil before planting, increasing the soil fertility, properly applying an organic fertilizer, and controlling the use amounts of a nitrogen fertilizer and a chemical fertilizer at the same time; 2, soil disinfection is conducted on planting compartment surfaces before planting; (3) disinfecting seminal roots; 4, management is enhanced, and air permeability and drainage of the soil are kept; 5) regularly inspecting the plants after seedling emergence, and timely removing infected parts; 6) spraying the plant rhizomes with a pesticide for prevention and control; (7) proper plant spacing and a good ventilation environment are kept. The method has the advantages of being easy and convenient to operate, low in cost and obvious in economic benefit and social benefit, effectively solves the disease problem of damping off of the radix pseudostellariae, can ensure the quality and safety of medicinal materials while increasing the yield of the radix pseudostellariae, and is widely suitable for production and planting of the radix pseudostellariae.

The invention provides an unmanned aerial vehicle prevention and control method and system for disease and insect pest monitoring, and relates to the technical field of path planning, and the method comprises the steps: controlling an unmanned aerial vehicle to fly along an initial inspection path; determining disease and pest occurrence points, and determining a disease and pest occurrence point set according to the disease and pest occurrence points; determining a plurality of risk areas; determining a target hovering entry point based on each risk area; the current position and environment information of the unmanned aerial vehicle are obtained, a three-dimensional discrete grid field is constructed based on the target hovering entry point and the current position and environment information of the unmanned aerial vehicle, and the three-dimensional discrete grid field comprises a plurality of grid units and corresponding grid risk values; and in the three-dimensional discrete grid field, generating a plurality of candidate tracks based on an RRT algorithm, and determining a transition track based on a target hovering entry point and a grid risk value in combination with wind field analysis. The selection of the target hovering entry point effectively avoids the problem of unstable flight caused by local airflow disturbance in the approaching and hovering process of the unmanned aerial vehicle.

The invention belongs to the field of agricultural bactericides, and particularly relates to a colza sclerotinia rot sterilization composition containing green biocontrol bacteria and application of the colza sclerotinia rot sterilization composition. The colza sclerotinia rot sterilization composition comprises a bacillus amyloliquefaciens WHIG fungicide and cantharidin; the mass ratio of the bacillus amyloliquefaciens WHIG microbial inoculum to the cantharidin is (20: 1)-(1: 20). A biological control strategy is adopted, the application amount of chemical agents can be reduced, the stability of biological control is improved, the effect of effectively controlling diseases can be achieved, and the composition shows a remarkable synergistic effect.

This invention provides methods to determine the stage in the natural time course of immune response in a subject. It describes method to control immune response by targeting regulatory mechanisms differentially operating in lymphocytes at different stages in the natural time course of immune response. One kind of such regulatory mechanism is the mechanisms of energy metabolism that control intracellular pH (pHi), which in turn control cell death and proliferation. This invention also describes a combinatorial approach to lowering pHi of neoplastic cells to induce their death using compositions of combinations of regulators of energy metabolism. Finally, this invention provides methods to treat skin or mucosa infections or neoplasia by topical application of pH modifier(s) that lower pH.

The invention belongs to the technical field of biological medicine, and discloses application of JAM3 protein in preparation of a medicine for inhibiting formation of a neutrophil extracellular trapping net. JAM3 is an I-type single transmembrane protein containing 310 amino acids, and belongs to an immunoglobulin superfamily. Researches show that the JAM3 protein remarkably inhibits excessive formation of a sepsis neutrophile granulocyte extracellular trapping net by regulating and controlling an activation path of neutrophile granulocytes, and meanwhile prevents blood platelets from being excessively captured, so that formation of microthrombus in the liver and damage to organs are avoided, disease progression is effectively controlled, and recovery of peripheral blood cells and organisms is promoted.

This disclosure provides microbial consortia to target Colletotrichum or Botrytis species that target flowers, such as those of blueberries, to control diseases caused by these phytopathogenic species. Methods of delivery of the consortia to plants, including pre-blossom and post-blossom stages.

The present invention provides the application of a pear short peptide PbePEP4 in plant disease prevention and control, specifically the application of a pear (Pyrus betulifolia) short peptide PbePEP4 in the prevention and control of apricot fire blight, rapeseed sclerotinia and watermelon gray mold. The present invention artificially synthesizes the short peptide PbePEP4 for the first time, clarifies its stimulating effect on the resistance to the above-mentioned diseases, and provides a method of spraying pears, rapeseed and watermelon to stimulate their resistance to fire blight, sclerotinia and gray mold, thereby preventing and controlling the above-mentioned diseases. The PbePEP4 short peptide provided by the present invention is a product synthesized by the plant itself. The use of the short peptide to stimulate immunity and thus prevent and control diseases has the advantages of being natural, green, environmentally friendly, and not inducing pathogens to develop drug resistance. In addition, the short peptide is easy to synthesize artificially, is easy to obtain, has a strong disease resistance stimulating effect, and requires a low concentration. It is a new type of ecological and environmentally friendly crop disease prevention and control preparation.

The present invention belongs to the technical field of pesticide bactericidal, and discloses a bactericidal composition and its application. The bactericidal composition comprises active ingredient A and active ingredient B. The active ingredient A is any one of tebuconazole, ethaboxam or amisulbrom, and the active ingredient B is fluoxapiprolin. The mass ratio of the active ingredient A to the active ingredient B is 1:40 to 45:1. The bactericidal composition of the present invention can effectively control plant oomycete diseases, can slow down the generation and development of pathogen drug resistance while controlling diseases, has a remarkable bactericidal effect, and has good safety for crops.

The application provides a disease and pest control method for Dendrobium cultivation, comprising: obtaining a UAV aerial image, identifying a suspected disease and pest area based on the UAV aerial image, and sending the position of the suspected disease and pest area to a background system; obtaining environmental parameters, analyzing the influence weight of the environmental parameters on diseases and pests, and performing disease and pest risk prediction to obtain a risk prediction result; starting a control measure when the risk value exceeds a warning threshold according to the risk prediction result, adjusting the environment through a sunshade and a ventilation device, collecting a plant image to identify a disease spot coverage rate, and adjusting a control frequency according to the coverage rate.

The present application relates to a kind of fungicidal composition containing prothioconazole and mefenoxam in the use for preventing and treating peanut diseases;The pesticide composition at least includes active ingredient A prothioconazole and active ingredient B mefenoxam, the mass ratio of the active ingredient A prothioconazole and active ingredient B is 1:50-50:1.The fungicidal composition of the present application can be used for preventing and treating various diseases on peanut, has good control effect, can prolong the effective period of pesticide, reduce the frequency of use, effectively reduce the use amount of active ingredient and use cost, delay the generation and development of resistance, and is environment-friendly.

The present invention relates to a method of controlling phytopathogens in rice crop. More particularly, the present invention relates to a method of controlling rice blight in rice cultivations. The present invention further relates to a fungicidal combination for controlling diseases in rice crop.

The invention discloses a compound microorganism for preventing and treating chestnut fruit rot and application of the compound microorganism. The compound microorganism is composed of trichoderma atroviride, bacillus siamensis and bacillus velezensis, and is constructed by directionally screening strains with broad-spectrum inhibition effect on seven core pathogenic bacteria from Chinese chestnut fruit endophytes and verifying compatibility. The method has the advantages that the compound flora synergistically prevents and controls diseases through direct antagonism and induction of plant system resistance, and the defensive enzyme activity and the content of total polyphenol and total flavone of Chinese chestnuts are remarkably improved; according to the compound microorganism, the indoor control effect reaches 90% (the morbidity is reduced), the diseased fruit rates of Chinese chestnut fruits treated in a chestnut garden are reduced by 60% and 42.86% respectively after the Chinese chestnut fruits are stored for 30 days and 120 days, the effectiveness and the stability are obviously higher than those of a single strain, the compound microorganism can be introduced in the flowering period or sprayed in the storage period, use is convenient and flexible, and an efficient and stable biocontrol strategy is provided for green prevention and control of the Chinese chestnut fruit rot.

According to one embodiment of the present invention, the smart livestock housing system capable of active disease prediction and control based on data-driven intelligent spraying and air conditioning technology is specifically a technology designed to prevent predictable diseases and actively control quarantine systems within farms to prevent animal infectious diseases and ultimately improve farm productivity. The smart livestock housing system may comprise: a housing for raising animals; a plurality of opening / closing ports formed on one side and another side of the housing, respectively, to control inflow of outside air into the interior; a breeding space installed inside the housing and formed to bound the space where animals are raised in all directions; at least one filter formed in one area constituting the breeding space; and an injector located between the opening / closing ports and the filter, operating to remove viruses by spraying disinfectant into outside air entering from the opening / closing ports.

The present invention relates to the technical field of data processing for pests and diseases of Paris vietnamensis, and discloses a data analysis system and method for preventing and controlling pests and diseases in Paris vietnamensis cultivation. By combining the identification information of the types of occluders in the growth images of Paris vietnamensis plants with the intelligent search algorithm and the type information of the preset standard occluder removal algorithm for the growth images of Paris vietnamensis plants, a precise analysis of the type of occluder feature removal algorithm in the growth images of Paris vietnamensis plants is carried out, so as to realize the scientific matching of the type of occluder interference features in the pest and disease monitoring images of Paris vietnamensis with the occluder removal algorithm object, and improve the quality of the acquisition of pest and disease monitoring images of Paris vietnamensis; independently and efficiently execute the preprocessing of removing the interference features of the occluders attached to the plant surface in the growth images of Paris vietnamensis plants, realize the efficient and precise processing of the occluder interference features in the pest and disease monitoring images of Paris vietnamensis, improve the authenticity of the acquisition of pest and disease monitoring images of Paris vietnamensis, and improve the prevention and control effect of pests and diseases in Paris vietnamensis cultivation.

This invention belongs to the field of biology and discloses a porcine Clostridium perfringens strain SP20 that secretes and expresses high levels of α-toxin. It is deposited at the China Center for Type Culture Collection (CCTCC) with accession number CCTCC NO: M 2025386. This bacterium exhibits strong pathogenicity in medium and large-sized pigs and can be used to establish porcine challenge models and evaluate the efficacy of porcine Clostridium perfringens type A vaccines. This invention also discloses a vaccine for preventing intestinal bloating and sudden death in medium and large-sized pigs caused by Clostridium perfringens type A. This vaccine contains α-toxin produced by the aforementioned SP20 strain. This invention fills the gap in the development of pathogenic models for intestinal bloating and sudden death in medium and large-sized pigs, which is beneficial for controlling disease transmission and reducing economic losses in the livestock industry.