67 results about "Control diseases" patented technology

The invention belongs to the technical field of microorganisms and biological control, and particularly relates to paenibacillus polymyxa and application thereof in biocontrol and growth promotion. Specifically, a strain of paenibacillus polymyxa GLZ219 is obtained through screening, and experiments prove that the paenibacillus polymyxa GLZ219 has a relatively high bacteriostasis rate on pathogenic bacteria of tomato neck and root rot; meanwhile, the strain has a good antagonistic effect on nine common plant pathogens such as Rhizoctonia solani and the like, and can be widely applied to green prevention and control of various crop diseases. Besides, the paenibacillus polymyxa GLZ219 has nitrogen fixing and potassium dissolving capabilities, can secrete heteroauxin and siderophores, and can effectively promote the growth of tomato plants, the plant height of tomato seedlings treated by fermentation liquor of the paenibacillus polymyxa GLZ219 is remarkably increased, diseases can be prevented and controlled, the growth vigor of crops can be improved, the yield and quality of the crops can be improved, and the paenibacillus polymyxa GLZ219 has a wide application prospect.

Provided are methods for treating pemphigus using an FcRn antagonist such as efgartigimod. The methods of the invention provide a rapid onset of action to enable early disease control and maintenance of clinical remission, with or without a minimal dose of corticosteroids.

The agriculture and forestry fruit tree pest control device comprises a placing plate and wheels, the outlet end of a water pump is communicated with a liquid conveying pipe, the other end of the liquid conveying pipe is communicated with a pesticide spraying rod, one end of the pesticide spraying rod is communicated with a spraying head, and a valve is arranged on the outer side of one end of the spraying head. When branches and leaves at the top end of the climbing frame need to be sprayed with pesticide, an electric telescopic rod drives a pesticide spraying rod to rotate around one end of a supporting seat, so that the pesticide spraying rod is in a vertical state, then a second motor drives a screw rod to spirally rotate on the inner side of a moving plate, and the moving plate drives the pesticide spraying rod to move upwards through the supporting seat; a pesticide spraying rod penetrates through a gap in the inner side of the climbing frame to move to the position above branches and leaves at the top end of the climbing frame, then an electric telescopic rod drives the pesticide spraying rod to be in a horizontal state, and then a water pump can spray pesticide liquid on the inner side of a pesticide storage box to the branches and leaves at the top end of the climbing frame through the pesticide spraying rod and a spray head through a liquid conveying pipe. Therefore, the branches and leaves at the top end of the climbing frame can be conveniently sprayed.

Provided herein are compounds of Formula (I): (I), or a pharmaceutically acceptable salt or composition thereof, which are useful in the treatment or management of diseases or disorders mediated by AAK1 activity, muscle diseases and disorders, and other conditions.

The invention relates to application of a moxibustion transdermal component citral in regulation and control of synovial fibroblast-like cell (FLS) proliferation and inflammatory factor secretion, and belongs to the technical field of medicines. In the background technology, rheumatoid arthritis (RA) treatment depends on drugs, but has the defects of great side effects, easy recurrence and the like. It is found through experiments that within the concentration range of 0.131-13.1 [mu] M, citral can effectively inhibit FLS proliferation and regulate secretion of inflammatory factors IL-6 and TNF-alpha. The invention provides a safe and effective replacement therapy, and citral is used for regulating and controlling the FLS function so as to control the progress of RA disease and improve the joint function and life quality of a patient. The method has the advantages of high safety, low cost, multi-target effect and remarkable innovativeness and practicability.

The invention relates to a composition for preventing and treating plant diseases and application thereof, and belongs to the technical field of disease and pest control. The invention provides a composition for preventing and treating plant diseases. The composition is prepared from the following components in parts by mass: 5 to 15 parts of eugenol, 1 to 10 parts of fructus psoraleae extract, 2 to 8 parts of litsea cubeba extract and 6 to 12 parts of kasugamycin. According to the scheme, the components of the composition have a synergistic effect and have a remarkable bactericidal effect on various plant disease pathogenic bacteria, the prepared preparation has a good control effect on plant diseases and can control disease indexes, the dosage of the preparation is remarkably reduced compared with that of a conventional agent, and the cost of disease and pest control is greatly saved.

The application discloses a primer, a probe composition for nontuberculous mycobacteria typing and application thereof, and provides a PCR primer and a probe for rapid detection and typing of 13 common NTM in clinic based on genome big data for carrying out pan-genomics analysis, and the specific genes of the common NTM in clinic are screened by using a pan-genomics method, and then typing primers and probes are designed based on the genes, so that the problems of insufficient accuracy and specificity in NTM typing are solved; the various NTM specific sequences screened guarantee the accuracy and specificity; the high sensitivity of the PCR method and the specificity of the sequences guarantee that various interference substances in the clinical samples can be avoided, and the clinical samples can be directly analyzed; the PCR detection is low in cost and low in equipment requirement, and can be carried out in primary hospitals, thereby providing an efficient and economical solution for the precise diagnosis of nontuberculous mycobacteria, the control of disease prevalence and the large-scale disease screening.

The invention discloses a comprehensive prevention and control method for tobacco pepper vein mottle virus disease, which comprises the following steps: S1, optimizing agricultural layout and preparing a field parcel: selecting an area far away from a vegetable field, a curing barn and an airing shed as a seedling raising and planting field, removing weeds in the seedling raising and planting field, then intercropping gramineous crops, and deeply ploughing and sunning upturned soil before winter; s2, prevention and control management in a seedling raising period: detecting pathogens, preventing and controlling diseases and pests, and managing, cleaning and disinfecting facilities; the application not only pays attention to reasonable use of pesticides, but also combines physical prevention and control (such as covering an insect-proof net), biological prevention and control and agricultural management (such as crop rotation and weed removal) to form a comprehensive prevention and control system; the virus resistance of the tobacco can be effectively improved, and meanwhile, the influence on the environment is reduced; aphidius avenae is used for biological control, biological insecticides (such as sophocarpidine and azadirachtin) are released to be alternately used with chemical agents, natural enemies are effectively utilized for pest control, and use of the chemical agents is reduced.

The invention provides an unmanned aerial vehicle prevention and control method and system for disease and insect pest monitoring, and relates to the technical field of path planning, and the method comprises the steps: controlling an unmanned aerial vehicle to fly along an initial inspection path; determining disease and pest occurrence points, and determining a disease and pest occurrence point set according to the disease and pest occurrence points; determining a plurality of risk areas; determining a target hovering entry point based on each risk area; the current position and environment information of the unmanned aerial vehicle are obtained, a three-dimensional discrete grid field is constructed based on the target hovering entry point and the current position and environment information of the unmanned aerial vehicle, and the three-dimensional discrete grid field comprises a plurality of grid units and corresponding grid risk values; and in the three-dimensional discrete grid field, generating a plurality of candidate tracks based on an RRT algorithm, and determining a transition track based on a target hovering entry point and a grid risk value in combination with wind field analysis. The selection of the target hovering entry point effectively avoids the problem of unstable flight caused by local airflow disturbance in the approaching and hovering process of the unmanned aerial vehicle.

The invention belongs to the field of agricultural bactericides, and particularly relates to a colza sclerotinia rot sterilization composition containing green biocontrol bacteria and application of the colza sclerotinia rot sterilization composition. The colza sclerotinia rot sterilization composition comprises a bacillus amyloliquefaciens WHIG fungicide and cantharidin; the mass ratio of the bacillus amyloliquefaciens WHIG microbial inoculum to the cantharidin is (20: 1)-(1: 20). A biological control strategy is adopted, the application amount of chemical agents can be reduced, the stability of biological control is improved, the effect of effectively controlling diseases can be achieved, and the composition shows a remarkable synergistic effect.

This invention provides methods to determine the stage in the natural time course of immune response in a subject. It describes method to control immune response by targeting regulatory mechanisms differentially operating in lymphocytes at different stages in the natural time course of immune response. One kind of such regulatory mechanism is the mechanisms of energy metabolism that control intracellular pH (pHi), which in turn control cell death and proliferation. This invention also describes a combinatorial approach to lowering pHi of neoplastic cells to induce their death using compositions of combinations of regulators of energy metabolism. Finally, this invention provides methods to treat skin or mucosa infections or neoplasia by topical application of pH modifier(s) that lower pH.

The invention belongs to the technical field of biological medicine, and discloses application of JAM3 protein in preparation of a medicine for inhibiting formation of a neutrophil extracellular trapping net. JAM3 is an I-type single transmembrane protein containing 310 amino acids, and belongs to an immunoglobulin superfamily. Researches show that the JAM3 protein remarkably inhibits excessive formation of a sepsis neutrophile granulocyte extracellular trapping net by regulating and controlling an activation path of neutrophile granulocytes, and meanwhile prevents blood platelets from being excessively captured, so that formation of microthrombus in the liver and damage to organs are avoided, disease progression is effectively controlled, and recovery of peripheral blood cells and organisms is promoted.

This disclosure provides microbial consortia to target Colletotrichum or Botrytis species that target flowers, such as those of blueberries, to control diseases caused by these phytopathogenic species. Methods of delivery of the consortia to plants, including pre-blossom and post-blossom stages.

The present invention provides the application of a pear short peptide PbePEP4 in plant disease prevention and control, specifically the application of a pear (Pyrus betulifolia) short peptide PbePEP4 in the prevention and control of apricot fire blight, rapeseed sclerotinia and watermelon gray mold. The present invention artificially synthesizes the short peptide PbePEP4 for the first time, clarifies its stimulating effect on the resistance to the above-mentioned diseases, and provides a method of spraying pears, rapeseed and watermelon to stimulate their resistance to fire blight, sclerotinia and gray mold, thereby preventing and controlling the above-mentioned diseases. The PbePEP4 short peptide provided by the present invention is a product synthesized by the plant itself. The use of the short peptide to stimulate immunity and thus prevent and control diseases has the advantages of being natural, green, environmentally friendly, and not inducing pathogens to develop drug resistance. In addition, the short peptide is easy to synthesize artificially, is easy to obtain, has a strong disease resistance stimulating effect, and requires a low concentration. It is a new type of ecological and environmentally friendly crop disease prevention and control preparation.

The application provides a disease and pest control method for Dendrobium cultivation, comprising: obtaining a UAV aerial image, identifying a suspected disease and pest area based on the UAV aerial image, and sending the position of the suspected disease and pest area to a background system; obtaining environmental parameters, analyzing the influence weight of the environmental parameters on diseases and pests, and performing disease and pest risk prediction to obtain a risk prediction result; starting a control measure when the risk value exceeds a warning threshold according to the risk prediction result, adjusting the environment through a sunshade and a ventilation device, collecting a plant image to identify a disease spot coverage rate, and adjusting a control frequency according to the coverage rate.

The present application relates to a kind of fungicidal composition containing prothioconazole and mefenoxam in the use for preventing and treating peanut diseases;The pesticide composition at least includes active ingredient A prothioconazole and active ingredient B mefenoxam, the mass ratio of the active ingredient A prothioconazole and active ingredient B is 1:50-50:1.The fungicidal composition of the present application can be used for preventing and treating various diseases on peanut, has good control effect, can prolong the effective period of pesticide, reduce the frequency of use, effectively reduce the use amount of active ingredient and use cost, delay the generation and development of resistance, and is environment-friendly.

The present invention relates to a method of controlling phytopathogens in rice crop. More particularly, the present invention relates to a method of controlling rice blight in rice cultivations. The present invention further relates to a fungicidal combination for controlling diseases in rice crop.

The invention discloses a compound microorganism for preventing and treating chestnut fruit rot and application of the compound microorganism. The compound microorganism is composed of trichoderma atroviride, bacillus siamensis and bacillus velezensis, and is constructed by directionally screening strains with broad-spectrum inhibition effect on seven core pathogenic bacteria from Chinese chestnut fruit endophytes and verifying compatibility. The method has the advantages that the compound flora synergistically prevents and controls diseases through direct antagonism and induction of plant system resistance, and the defensive enzyme activity and the content of total polyphenol and total flavone of Chinese chestnuts are remarkably improved; according to the compound microorganism, the indoor control effect reaches 90% (the morbidity is reduced), the diseased fruit rates of Chinese chestnut fruits treated in a chestnut garden are reduced by 60% and 42.86% respectively after the Chinese chestnut fruits are stored for 30 days and 120 days, the effectiveness and the stability are obviously higher than those of a single strain, the compound microorganism can be introduced in the flowering period or sprayed in the storage period, use is convenient and flexible, and an efficient and stable biocontrol strategy is provided for green prevention and control of the Chinese chestnut fruit rot.

According to one embodiment of the present invention, the smart livestock housing system capable of active disease prediction and control based on data-driven intelligent spraying and air conditioning technology is specifically a technology designed to prevent predictable diseases and actively control quarantine systems within farms to prevent animal infectious diseases and ultimately improve farm productivity. The smart livestock housing system may comprise: a housing for raising animals; a plurality of opening / closing ports formed on one side and another side of the housing, respectively, to control inflow of outside air into the interior; a breeding space installed inside the housing and formed to bound the space where animals are raised in all directions; at least one filter formed in one area constituting the breeding space; and an injector located between the opening / closing ports and the filter, operating to remove viruses by spraying disinfectant into outside air entering from the opening / closing ports.

This invention belongs to the field of biology and discloses a porcine Clostridium perfringens strain SP20 that secretes and expresses high levels of α-toxin. It is deposited at the China Center for Type Culture Collection (CCTCC) with accession number CCTCC NO: M 2025386. This bacterium exhibits strong pathogenicity in medium and large-sized pigs and can be used to establish porcine challenge models and evaluate the efficacy of porcine Clostridium perfringens type A vaccines. This invention also discloses a vaccine for preventing intestinal bloating and sudden death in medium and large-sized pigs caused by Clostridium perfringens type A. This vaccine contains α-toxin produced by the aforementioned SP20 strain. This invention fills the gap in the development of pathogenic models for intestinal bloating and sudden death in medium and large-sized pigs, which is beneficial for controlling disease transmission and reducing economic losses in the livestock industry.

The present invention relates to the technical field of aquaculture methods, and specifically to a transportation method and a transportation system for farmed long-snouted catfish that improve the survival rate. The transportation method includes the entire process from pre-catching preparation to recuperation at the breeding ground, and the transportation system includes a pre-transportation treatment unit, a transportation unit, and a post-transportation temporary holding unit. By using the above-mentioned system and the above-mentioned method, the purpose of promoting the recovery of long-snouted catfish wounds and preventing and controlling diseases such as bacteria, molds, Ichthyophthirius and spores can be achieved, and it is suitable for daily long-distance transportation, parent transportation and cultivation of long-snouted catfish. This technical solution can solve the technical problem of the high mortality rate of long-snouted catfish after long-distance transportation in the prior art. This transportation method and system that improves the survival rate not only solves the challenges faced by long-snouted catfish during transportation, but also has important significance for promoting the healthy and stable development of the long-snouted catfish industry, and has ideal application and promotion prospects.

The application discloses a strain of Pseudomonas extremorientalis LJ-6 and application of the strain in preventing and controlling mulberry diseases. The Pseudomonas extremorientalis in the application is preserved in the Guangdong Microbial Culture Collection Center on June 18, 2024, and the preservation number is GDMCC NO: 64766. The Pseudomonas extremorientalis LJ-6 has good antagonistic effects on bacterial pathogenic bacteria such as Caulobacter segnis, Pantoea ananatis, Klebsiella michiganensis and Enterobacter cloacae, and fungal pathogenic bacteria such as Fusarium oxysporum, Curvularia lunata and Guignardia bidwellii. The Pseudomonas extremorientalis LJ-6 has good prevention and control effects on plant diseases caused by the above pathogenic bacteria invading plants, such as mulberry bacterial wilt, mulberry bacterial blight, mulberry leaf spot and mulberry anthracnose. Therefore, the Pseudomonas extremorientalis LJ-6 has good application prospect and value in preventing and controlling plant diseases such as mulberry and preparing disease prevention and control preparation products.

The invention discloses bombyx mori circRNA as well as an inhibitor and application thereof. The bombyx mori circRNA is bmocirc0000157, and the nucleotide sequence of the bombyx mori circRNA is shown as SEQ ID NO.3; according to the invention, the mechanism that the bmocirc0000157 is used as the molecular sponge of the miR-281-5p to regulate and control the proliferation of the nosema bombycis is clear, the expression of the bombyx bombycis bmocirc0000157 is inhibited or the proliferation of the nosema bombycis can be inhibited by overexpressing the miR-281-5p, and a reference is provided for analyzing the infection mechanism of the nosema bombycis and preventing and controlling diseases.

The invention belongs to the technical field of gene engineering, and discloses a disease-resistant gene NbSTOMR and application thereof in improving the disease resistance of plants and preventing and controlling diseases, the sequence of a protein coded by the gene is shown as SEQ ID NO.2, and the nucleotide sequence of the coded protein is shown as SEQ ID NO.1. Molecular genetic experiments show that after the NbSTOMR gene is knocked out from tobacco, cell death and reactive oxygen generation induced by the pathogen-related molecular mode STOM are remarkably weakened, and the NbSTOMR is considered to be a mode recognition receptor for recognizing the pathogen-related molecular mode STOM. Importantly, the disease resistance of a tobacco knockout body (nbstomr) of the NbSTOMR gene to sclerotinia sclerotiorum is remarkably weakened, and the disease resistance of the Bensi tobacco to sclerotinia sclerotiorum is remarkably enhanced by expressing the gene. Therefore, the NbSTOMR provided by the invention is a disease-resistant related mode recognition receptor in the tobacco, can improve the disease resistance of the tobacco to sclerotinia sclerotiorum, and can be applied to disease-resistant breeding of the tobacco.

The invention provides application of clostridium papyrosolvens, thymine or probiotics overexpressing pyrimidine nucleoside phosphorylase from the clostridium papyrosolvens to preparation of drugs for regulating and controlling diseases related to glucose and lipid metabolism disorder, and belongs to the technical field of biological drugs. The invention further discloses application of the probiotics of the clostridium papyrosolvens, thymine or the pyrimidine nucleoside phosphorylase over-expressed from the clostridium papyrosolvens to preparation of the medicine for regulating and controlling the diseases related to the glucose and lipid metabolism disorder. The clostridium papyrosolvens significantly inhibits weight gain of mice induced by high fat diet and induces metabolism remodeling of the mice; the glycolipid metabolism disorder caused by high fat diet induction can be remarkably improved by treating the metabolite thymine of the clostridium papyrosolvens. The clostridium papyrosolvens and the metabolite thymine thereof provided by the invention can be used for preparing food or medicines for preventing or treating metabolic diseases, and have very wide application prospects.

The present invention belongs to the field of pesticide sterilization technology and discloses a sterilization composition and its use. The sterilization composition comprises active ingredient A and active ingredient B, wherein active ingredient A is any one of tetrazolium pyraclostrobin, ethaboxam, or indazole sulfaquinoxaline; active ingredient B is fluoxapiprolin; and the mass ratio of active ingredient A to active ingredient B is 1:40 to 45:1. The sterilization composition of the present invention can effectively prevent and control plant oomycete diseases, while preventing and controlling diseases, and can slow the development and progression of drug resistance in pathogens. It has a significant sterilization effect and is safe for crops.

The invention discloses a crop growth state-based intelligent pest and disease damage prediction, prevention and control method, which comprises the following steps of: acquiring multi-source observation data related to a crop growth state and a crop growth environment in a crop growth process, and preprocessing the data to obtain multi-source heterogeneous data of crops; inputting the multi-source heterogeneous data into a pest and disease damage prediction model to predict the occurrence probability of the pest and disease damage in the current growth state and the growth environment, outputting a pest and disease damage prediction result according with the current crop growth state, and performing prevention and control analysis on the pest and disease damage prediction result through a pest and disease damage prevention expert knowledge base. And generating corresponding prevention and control decisions, sending the decisions to corresponding management personnel terminals for disease and pest prevention and control early warning, monitoring disease and pest prevention and control effects of the prevention and control decisions, feeding back the disease and pest prevention and control effects to the disease and pest prediction model for model optimization, and adaptively updating the disease and pest prediction model. The effects of improving the yield and quality of crops and effectively preventing and controlling diseases and pests in the whole growth period of the crops are achieved.

A composition suitable for control of diseases caused by phytopathogens comprising (A) a compound of formula (I) wherein R1 is C1-C6 alkyl, C1-C6 haloalkyl, C1-C3 alkoxyC1-C3 alkyl, C3-C5 cycloalkyl, C2-C4 alkenyl, C2-C4 alkynyl; R2 is hydrogen, C1-C3 alkyl, C1-C3 alkoxy or C3-C5 cycloalkyl; R3 is C1-C6 alkyl; R4 is hydrogen or fluoro and A is 1,4-phenyl or 2,5-thienyl; and (B) at least one compound selected from compounds known for their fungicidal activity; and a method of controlling diseases on useful plants, especially rust diseases on soybeans or cereals.

The application discloses a kind of for preventing and treating chestnut fruit rot disease complex microorganism and its application.The application complex microorganism is composed of Trichoderma atroviride and Bacillus siamensis, Bacillus velezensis, by from chestnut fruit endophyte directional screening to seven kinds of core pathogenic bacteria have broad-spectrum inhibitory effect strain, is constructed after compatibility verification.It is superior in that: complex microbial population is synergistically controlled disease by direct antagonism and induced plant system resistance, significantly improves chestnut defense enzyme activity and total polyphenol, total flavone content;Indoor control efficiency reaches 90% (reduces the incidence), chestnut fruit in chestnut orchard treatment is reduced 60% and 42.86% respectively in 30 days and 120 days, effective and stability are obviously stronger than single strain, and the application complex microorganism can be introduced by flowering period or sprayed in storage period, and is convenient and flexible, provides efficient, stable biocontrol strategy for chestnut fruit rot green control.