72 results about "Early disease" patented technology

New and improved applications of Raman Scattering are disclosed. These applications may be implemented with or without using an enhanced nano-structured surface that is trademarked as the RamanNanoChip™ disclosed in a pending patent. As a RamanNanoChip™ provides much higher sensitivity in SERS compared with conventional enhance surface, broader scopes of applications are now enabled and can be practically implemented as now disclosed in this application. Furthermore, a wide range of applications is achievable as new and improved Raman sensing applications. By applying the analysis of Raman scattering spectrum, applications can be carried out to identify unknown chemical compositions to perform the tasks of homeland security; food, drug and drinking materials safety; early disease diagnosis environmental monitoring; industrial process monitoring, precious metal and gem authentications, etc.

The present invention relates to the analysis and monitoring of ocular fluids for determining the physiological state of an organism, to monitor drug efficacy and dynamics, for early disease detection, as well as to certain molecular markers and fingerprints of identified molecules or molecule fragments in such analysis.

The invention discloses a multilayer information monitoring early warning method of early diseases of crops. The objective is to provide a lossless monitoring method of early diseases of crops. The method comprises steps of shooting the whole crop to obtain an object infrared image; calculating the average temperature of a monitoring object pixel point, the average temperature of a low-temperature pixel point and the average temperature of a high-temperature pixel point, and calculating the temperature difference between the average temperature of the low-temperature pixel point and the average temperature of the high-temperature pixel point; comparing the temperature difference with a monitoring threshold value and taking the temperature difference as the basis for determining whether the crops are infected with diseases; using a visible light-near infrared high spectral imaging device to monitor the crops suffering the diseases to obtain characteristic images; using a microscopy imaging device to monitor disease speckles in the characteristic images,= to obtain microscopy images; and according to a microscopy image gray scale histogram, estimating the early disease degree of the crops by combining the characteristic images. According to the invention, multilayer information of temperatures, pigments and textures of the crops is monitored; and disease detection and precise analysis in the incubation period and at the disease early stage are achieved.

The invention provides LAMP (Loop-mediated Isothermal Amplification) primers for rapidly assaying tea tree anthracnose pathogens and an assay method. Aimed at the beta-tubulin(TUB2) gene sequence of tea tree anthracnose pathogens, the invention designs and screens out a set of specific assay primer group, and the primer group consists of four specific primers F3, B3, FIP and BIP. The primers screened out by the invention have high sensitivity and strong specificity, the established assay method ha the advantages of high accuracy, strong specificity, easiness in operation, short assay time, simple instruments and equipment and the like, and is applicable to the high-sensitivity rapid assay, identification and early disease diagnosis of tea tree anthracnose pathogens in diseased tissues andpathogen-carrying plants, and for the early monitoring of tea tree anthracnose in agricultural production, the invention is of great significance for the determination of optimal prevention and control time.

The invention discloses a kit for early screening of the lung cancer based on peripheral blood. The kit comprises a connector, a PCR primer and a capture probe. The connector comprises a Tag sequence,a Poly N sequence, a first hairpin sequence, a second hairpin sequence, a first index sequence, a first common primer combination sequence, a second common primer combination sequence and dUTP, and the first index sequence is used for distinguishing different peripheral blood samples; the PCR primer is a primer designed for 358 genes which are related to the pulmonary nodule and indirectly influence proliferation and differentiation of cells, and the PCR primer is used for being combined with the connector; the capture probe is a probe designed for the 358 genes which are related to the pulmonary nodule and indirectly influence proliferation and differentiation of the cells, and the capture probe is used for capturing a cfDNA area of plasma in the peripheral blood samples. The provided kit can be applied to early disease screening of the lung cancer, and the pulmonary nodule is diagnosed in a noninvasive and high-sensitivity mode.

Musculoskeletal fibroproliferative disorders, such as Dupuytren's disease may be treated by administering locally a TNF-α antagonist. TNF-α antagonists find particular utility in inhibiting the progression of early disease state Dupuytren's disease and other musculoskeletal fibroproliferative disorders and, in combination with extracellular matrix degradation agents (such ascollagenase or matrix metalloproteinase I), treating advanced disease state Dupuytren's disease and, in particular inhibiting recurrence.

The invention relates to Blackberrylily rhizome antiviral injection, preparation and venous medicine feeding blackberrylily rhizome antiviral injection thereof. The original medicine comprises 1-1000 portion of belamcanda rhizome by weight, 1-1000 portion of honeysuckle by weight, 1-1000 portion of Eupatorium by weight, 1-1000 portion of capilary artemisia by weight, 1-1000 portion of radix bupleuri by weight, 1-1000 portion of dandelion by weight, 1-1000 portion of isatis root by weight, 1-1000 portion of dyers woad leaf by weight. The medicine is obtained by following steps: distilling by vapor, boiling, adding adding clarifier, alcohol-settling, water-settling, centrifugation, hyperfiltration to get active component of the Blackberrylily rhizome antiviral injection, and then subpackaging, disinfecting to get finished preparation, in which the chlorogenic acid (C16H18O9) is not less than 0.5 mg / ml. The injection has the function of antivirus and killing bacteria and relieving inflammation and treating epidemic hemorrhagic fever early disease. The invention avoids the medicine liquid thickness, deposition and color changing, stabilizes the preparation, prolongs the product effective date. The injection can be applied through vein so as to prevent the adverse effects such as pain in the administration location, blood stasis and even muscle necrosis.

The invention discloses a method for monitoring a crop disease and comprehensively evaluating the degree of the disease by virtue of an infrared image, and belongs to an optical nondestructive early crop disease monitoring method. The method comprises the following steps: shooting the whole crop or shooting all crops in a certain planting region to obtain an infrared image of a monitoring object; calculating the average temperature of all pixels of the monitoring object, the low-temperature area sum of low-temperature pixels, the high-temperature area sum of high-temperature pixels and the total temperature area of all the pixels according to the infrared image respectively, and calculating the ratio of the low-temperature area sum to the total temperature area; taking the ratio as a comprehensive valuation parameter for the degree of the crop disease. According to the method, an early disease imperceptible for eyes can be nondestructively and accurately identified on line, and the detection and analysis time and cost can be reduced; the method can also be used for comprehensive evaluation for nondestructive monitoring of the health condition of the crop.

The invention discloses a device and a method for detecting a blood vessel. The device comprises a visible light source, an optical fiber coupler, a lighting optical fiber, an imaging receiving channel, an infrared beam splitter, a far infrared lens zoom system, a far infrared detector, a visible light lens zoom system, a visible light image sensor and an image processing system. According to the characteristic and the blood vessel blood flow heat transfer property that different heat radiation is generated by metabolic activity of hot body cells, tissues or organs in different states, infrared thermal imaging technology is integrated with visible light imaging technology, a high-quality and high-contrast blood vessel image is acquired, analysis of related blood flow parameters such as blood vessel blood flow speed and blood perfusion can be assisted, and early disease prediction and health assessment are performed according to temperature characteristics of human tissues under different pathologies.

The invention belongs to the technical field of plant root-knot nematode inoculation methods, and particularly provides a plant root-knot nematode potting three-layer sick soil inoculation method. Themethod comprises the steps of 1, disease-free soil collection and treatment; 2, sick soil collection and treatment; 3, sick soil expanding propagation cultivation; 4, expanded propagation sick soil pretreatment; and 5, three-layer sick soil inoculation. The plant root-knot nematode potting three-layer sick soil inoculation method adopts a three-layer sick soil inoculation technology that disease-free soil is inoculated on upper and lower layers, and nematode sick soil is inoculated on a middle layer. Compared with an existing root-knot nematode egg and larvae inoculation technology, the technology approaches natural inoculation, the inoculation survival rate is high, a nematode selecting link is omitted, and the workload is greatly reduced. Compared with an existing root-knot nematode single sick soil inoculation technology, the technology has the advantages that the usage amount of the sick soil is reduced by 1 / 2-2 / 3, and the workload and cost of the collection, transportation, expanding propagation cultivation and the like of the sick soil are greatly reduced; and newly transplanted seedlings can be protected from being infected by nematodes, not only can the success of the inoculation be ensured, but also too early disease death of the seedlings can be avoided.

A system for predicting diseases may accumulate information about the volatile, semi-volatile, and non-volatile organic compounds in breath / saliva. Such information may be analyzed over time to identify early disease indications, using non-invasive data collection via breath and alert patients directly for follow-up with a health professional.