The invention relates to a chronic
heart failure dynamic course evolution prediction model construction method. Comprising the following steps: uniformly mapping continuous variables including LVEF and
heart rate and event variables into a
time trajectory frame through an event alignment and
time domain nesting strategy; using a local change rate
algorithm to identify inflection points including states before acute deterioration and intervention reactions in the course of
disease of each patient; constructing a state fragment set for supporting
hierarchical modeling in an evolution stage; a bidirectional fusion method of
trajectory clustering and
medical knowledge embedding is used to construct a
state space with clinical
interpretability including a compensation period, edge
decompensation and an acute deterioration period; taking the trajectory vector as a main input, taking a
state space as a prediction target, and introducing a dual-channel structure; predicting a future path based on the current state; the
disease course track change of early medication / non-hospitalization / treatment scheme change is simulated; a doctor is supported to deduce a result; the change of the output state is analyzed through perturbation of the current trajectory, and key variables are found out.