95 results about "Treatment options" patented technology

A Predictive Diagnostic Information Capability-Technology (PreDICT™) system (100) enables users including expert and nonexpert users to provide information regarding a condition of a subject and receive timely and accurate information regarding risk stratification, treatment options and other medical evaluation information. The illustrated system (100) generally includes a user device (102) for use by a user assisting a subject (104), a processing platform (108), and a network (106) for connecting the user device (102) to the processing platform (108). The system (100) may also involve an emergency response network (130) that includes public-safety answering points (PSAPs) (132). The processing platform (108) processes the sensor information and other information from the user device (102), determines risk stratification information as well as medical diagnosis and treatment option information based on machine learning technology, and provides output information to the user device to assist the user in treating the subject (104).

The invention relates to the technical field of medical information, and discloses a CRRT treatment intelligent safety early warning system based on multi-modal fusion, and the system comprises a data collection and fusion module which is used for collecting multi-modal data from a plurality of heterogeneous data sources in real time, carrying out the standardization and fusion processing of the multi-modal data, and generating fusion data with a unified time sequence; the knowledge model library is used for storing medical knowledge, clinical guidelines and historical data related to CRRT treatment and trained early warning and decision models; according to the system, through multi-modal data fusion and machine learning, the crossing from passive alarm to active early warning is realized, and the safety of a patient is remarkably improved. The intelligent decision support can output an individualized treatment scheme, promote precise medical treatment and optimize resource utilization, the system integration and grading alarm mechanism effectively reduces the cognitive load of medical care, and the self-learning ability of the system ensures that an early warning model can be continuously evolved and promotes the continuous improvement of clinical treatment quality.

Methods and systems for determining an expected disease treatment outcome upon treating a subject, methods and devices for selecting a treatment option for the subject, and methods of treating a subject for a disease, are described herein. The method can include receiving a plurality of subject characteristics for the subject; accessing a tree-based model corresponding to a treatment option for the disease, wherein the tree-based model is generated based on a plurality of prior patient characteristics and an associated treatment outcome for the corresponding treatment option; and determining from the plurality of subject characteristics and the tree-based model, an expected treatment outcome for the subject if the subject were treated with the corresponding treatment option.

An object of the system according to the embodiment is to allow a user to efficiently collect information on medical facilities and treatment options and make an optimal selection.SOLUTION: A system includes a reception part, an analysis part, a provision part, and a reservation part. The reception unit receives information on medical facilities and treatment options from a user. The analysis unit analyzes the information received by the reception unit and generates a list of related medical facilities and treatment options. The providing unit provides the user with the list generated by the analyzing unit. The reservation unit performs reservation and inquiry based on the list provided by the providing unit.SELECTED DRAWING: Figure 1

The present disclosure describes systems configured to recognize indicators of a medical condition within a diagnostic image and predict the progression of the medical condition based on the recognized indicators. The systems can include neural networks trained to extract disease features from diagnostic images and neural networks configured to model the progression of such features at future time points selectable by a user. Modeling the progression may involve factoring in various treatment options and patient-specific information. The predicted outcomes can be displayed on a user interface customized to specific representations of the predicted outcomes generated by one or more of the underlying neural networks. Representations of the predicted outcomes include synthesized future images, probabilities of clinical outcomes, and / or descriptors of disease features that may be likely to develop over time.

The invention belongs to the technical field of tumor immunotherapy, and relates to an anti-Claudin18.2 single-domain antibody, a multifunctional fusion protein, a recombinant natural killer cell (CT-CAR-NK), and preparation and application thereof. Through alpaca immunization and phage display library construction and panning, the single-domain antibody VHH-C18.2-1 specifically combined with Claudin18.2 is obtained, and the amino acid sequence of the single-domain antibody VHH-C18.2-1 is SEQ ID NO: 1. The amino acid sequence of the designed fusion protein is SEQ ID NO: 3, the fusion protein sequentially comprises a VHH-C18.2-1, a flexible Linker, a TGF-beta RII extracellular domain, a CD8alpha hinge region, a CD8alpha transmembrane region, a 4-1BB intracellular domain and a CD3zeta intracellular domain from the N end to the C end, and the fusion protein has the functions of targeting, resisting TGF-beta inhibition and activating signals. The fusion protein gene transfects human peripheral blood CD56 + CD3-NK cells through lentivirus to obtain CT-CAR-NK, in-vitro verification shows that the CT-CAR-NK still keeps efficient killing in an immunosuppression environment, tumor growth can be remarkably inhibited in vivo, the lifetime can be prolonged, and a safe and efficient scheme is provided for Claudin18.2 positive solid tumor treatment.

A system is provided.SOLUTION: A system, comprising: means for a user to input a diagnostic result; means for a server to pre-process the diagnostic result and extract key information; means for the server to interpret the diagnostic result using a AI model and generate therapy options; means for the server to present the interpretation result and the therapy options to the user; means for the server to search for recommended healthcare providers based on the diagnostic result and the therapy options; and means for a device to display the recommended healthcare providers to the user.SELECTED DRAWING: Figure 1

We provide the system. [Solution] An input means for inputting patient diagnostic information and image data, An analysis means that searches for similar cases from a past medical case database based on the data input via the aforementioned input means, A generation means that generates multiple treatment plans based on the results obtained by the analysis means, An evaluation means for calculating the suitability of the generated treatment options, A visualization means for visualizing and presenting the evaluation results obtained by the aforementioned evaluation means, A system that includes this.

This invention discloses an automated comparative analysis system and method for multiple clinical treatment options, belonging to the field of clinical data analysis. The system includes a data input layer, an analysis engine layer, and a structured output layer. It solves the technical problems of existing technologies, such as reliance on repetitive manual programming for multiple treatment option comparisons, fragmentation between matching analysis and multidimensional analysis, and difficulty in summarizing and reusing results. These problems include automatically triggering report generation and global index clustering based on joint significance judgment rules.

This invention provides a highly supportive mesh structure, comprising beam-column units and single expansion units. The beam-column units at both ends and the single expansion unit in the middle are connected to form a tubular mesh structure. Each single expansion unit is composed of single expansion grids axially connected by reinforcing bars, with the crests of radially adjacent single expansion grids arranged in an alternating pattern. This mesh structure exhibits strong radial support, low axial contraction, no sharp angles, and stable mechanical properties. It is adaptable to various cavities in the human body, enabling the establishment and maintenance of cavities blocked by various hard, sharp, and irregularly shaped foreign objects. This provides surgeons with a safer surgical procedure, increases their treatment options, and reduces patient pain and suffering during and after surgery.

This invention provides a treatment system for promoting dental pulp repair using oral stem cells, belonging to the field of oral treatment technology. The system utilizes a dynamic gene regulation module, an adaptive intelligent scaffold, and a bio-digital fusion interface in synergy. Through the dynamic gene regulation module and the adaptive intelligent scaffold, the efficiency and therapeutic effect of dental pulp regeneration are significantly improved. The dynamic gene regulation module employs a light-controlled CRISPR system to perform real-time gene editing on dental pulp stem cells, dynamically adjusting according to the needs of the regeneration stage. The adaptive intelligent scaffold, based on 3D printing technology and manufactured using a digital model of the patient's teeth, can dynamically release growth factors and optimize the microenvironment. This combination of personalized design and dynamic regulation allows for adaptive adjustments to meet the specific needs of the patient, not only improving the repair efficiency of dental pulp tissue but also enhancing the success rate of functional reconstruction. This provides patients with dental pulp injury with a more efficient and precise treatment option, promoting the personalized development of oral regenerative medicine.

A method and process for providing virtual screening of patients and medical personal implemented as a virtual universe in metaverse, typically with the help of a remote system having Artificial Intelligence with machine learning capability, for collection and presentation of patient's medical data is provided. Currently Doctors conduct virtual visits with patients to help collect patient's medical data and establish initial diagnosis. This is a time taking process and takes up a lot of the physician's and their assistant's valuable time and energy. Using the remote system to do the initial screening and collection of patients medical data for presentation to the physician before the virtual visit, will reduce the time physicians need to spend with the patient to arrive at a diagnosis. The capability will also help a physician to guide an assistant at a remote location to collect additional data of the patient.

The invention discloses a skin disease auxiliary system based on computer vision, and particularly relates to the technical field of skin disease assistance, which comprises a multi-modal data acquisition module, an image preprocessing module, a deep learning diagnosis module and a clinical decision support module, according to the method, integrated hardware for synchronously collecting visible light and polarized light images and temperature and humidity parameters is adopted, a focus area is automatically segmented through self-adaptive filtering denoising and an improved U-Net network, and a Dice loss function optimization model is adopted; the method comprises the following steps: constructing a double-branch CNN model, extracting lesion image features by a first branch, normalizing physiological parameters by a second branch, obtaining a disease classification result through a feature fusion layer, storing a skin disease clinical knowledge base, matching similar cases and treatment schemes according to diagnosis results, and generating a structured diagnosis report; if the diagnosis confidence is high, matching according to disease categories; otherwise, expanding the range to assist identification.

A mask-based diagnostic (MBD) system for remote patient monitoring that collects chemical biomarker data and non-chemical biometric data from patients in a non-invasive manner. The MBD can be used to monitor various medical conditions, including cardiovascular disease, lung cancer, diabetes, and respiratory diseases. The system consists of a mask having an exhaled breath condensate (EBC) collector that tests for chemical biomarkers in EBC. Non-chemical biometric data, such as temperature, heart rate, and blood oxygen levels can also be obtained using a wearable electronic device. The collected data is transmitted wirelessly to a remote server for aggregation, analysis, and interpretation using artificial intelligence (AI) algorithms. The AI algorithms detect patterns and trends in the patient data, which can be used for drug discovery, to identify health issues, adjust treatment plans, etc. The MBD can improve patient outcomes by providing real-time monitoring, early detection of health issues, and personalized treatment options.

Disclosed herein are system, apparatus, device, method and / or computer program product embodiments, and / or combinations and sub-combinations thereof, for detecting and displaying healthcare outlier data. Some embodiments involve: receiving a claim including a provider, an illness, a treatment, and a risk score based on the illness and the treatment; updating a metric associated with the provider based on the claim; normalizing the metric using the risk score, the illness, and the treatment; determining that the normalized metric is an outlier by: (1) comparing the normalized metric to a threshold and; (2) determining that the normalized metric is associated with a statistically significant number of claims; in response to determining that the normalized metric is an outlier, presenting an indication of the outlier to a user. In some embodiments, the presenting may further include transmitting an alert to user computing device associated with the user.

This invention discloses a polypeptide that specifically binds to the RNA-binding domain of the PRMT5 protein and its applications, belonging to the field of biomedical technology. The polypeptide specifically binds to the RNA-binding domain of the PRMT5 protein, and its amino acid sequence includes sequence A or sequence B. Sequence A is: LTNKKGFPVLSK; sequence B is: PGMFSWFPILFP. This polypeptide can precisely interfere with PRMT5-RNA interaction without affecting PRMT5 protein abundance, thereby specifically disrupting a key pathway for maintaining tumor protein translation. This polypeptide therapeutic agent has been shown to effectively inhibit tumor growth in preclinical models, validating the therapeutic feasibility of the "PRMT5-RBD targeting" strategy and providing a novel potential treatment option for patients (including those insensitive to or resistant to existing methylation inhibitors).

The utility model relates to the technical field of sitz bath, concretely is a kind of field portable foldable visible perianal sitz bath, including sitz bath main part, the sitz bath main part is inverted conical setting, the inside of sitz bath main part is close to the fixed connection of mirror with bottom position, the inside of sitz bath main part is close to the fixed connection of grid plate with mirror position, the beneficial effect of the utility model is through the mutual cooperation between sitz bath main part, mirror, grid plate, telescopic base, positioning sleeve, slide bar and direction mirror, the device can be shown to operating personnel by the two refractive modes of mirror and direction mirror with perianal affected area, and the size of affected area can also be estimated by grid plate, and the support height of sitz bath main part can be adjusted by the multiple structures of telescopic base, so that the height of sitz bath main part is more suitable for operating personnel, to ensure that perianal affected area size can be observed by oneself under field environment, and suitable treatment scheme is selected.

The invention discloses application of combination of carboxamidotriazole and revatinib in preparation of liver cancer drugs, a pharmaceutical composition and a preparation of the carboxamidotriazole and the revatinib, the drug combination of carboxamidotriazole and revatinib is used for the first time, the carboxamidotriazole and the revatinib show a remarkable synergistic effect, and in clinical medication, for patients with low sensitivity of using revatinib, the drug combination of carboxamidotriazole and revatinib has a remarkable curative effect on liver cancer. Through combination with carboxamidotriazole, the sensitivity of a patient to the medicine can be improved, and a synergistic effect is achieved. Meanwhile, as a non-cytotoxic drug, the carboxamide triazole can regulate the tumor inflammatory microenvironment, so that the tumor growth environment is changed, and the possibility of later development and metastasis of tumors is reduced. Meanwhile, the combination of carboxamidotriazole and lenvatinib has high safety, and provides more medication options for first-line patients.

The invention relates to a system comprising an anterior cervical plate with receiving openings for bone screws and a locking mechanism for inserted bone screws that are screwed to a vertebral body and press the cervical plate against the vertebral body, wherein the locking mechanism has a plate-type locking body (16) which is movably held on the cervical plate and which can be moved from a position that leaves a receiving opening as freely accessible as possible into a locking position in which the screw head lying in the receiving opening is covered by the locking body and thus the migration of the screw out of the cervical plate is prevented. In order to design the system in such a way that it is easy to operate while maintaining a high degree of security against a loosening of the bone screws and it offers maximum flexibility in the design of the cervical plate for a wide range of treatment options, the locking body is formed uniformly for cervical plates for hybrid and dynamic treatment options, by a thin disc (16) which is fixed to the anterior cervical plate so as to be rotatable about an axis of rotation substantially perpendicular to the cervical plate (10), and which has, angularly distributed over the circumference, at least one locking arm (18) and a support portion (20), which is a component of a catch mechanism.

A computer implemented method includes retrieving data from a patient's updated electronic medical record relevant to a diagnosis of a disease. The data includes medical images and at least one of the patient's demographic data, morbid symptoms, vital signs, medications, surgery history, family medical history, genetic data, laboratory test data, diseases records, allergies, and medical insurance information. The method includes generating available treatment path options including at least one surgical treatment or intervention, using at least one model to predict at least one implication for each of the available treatment path options based on the data and simulated adverse outcomes of the at least one surgical treatment or intervention simulated by predictive models including a biomechanical model based on the medical images. The method includes interactively updating and displaying a decision tree including the available treatment path options each with a corresponding at least one objective function.

The application relates to application of a medicine taking ACLY gene as an action target in preparation of a medicine for preventing and treating vascular calcification, and belongs to the technical field of biological medicine. In order to solve the problem that effective clinical means for treating vascular calcification is lacked at present, the application provides application of a medicine taking ACLY gene as an action target in preparation of a medicine for preventing and treating vascular calcification, the transcription or translation of the ACLY gene of vascular smooth muscle cells is efficiently and specifically inhibited, or the expression or activity of the ACLY protein of the vascular smooth muscle cells is efficiently and specifically reduced, the osteogenic differentiation of smooth muscle is reduced, the deposition of hydroxyapatite in the vascular media is reduced, and the progress of vascular calcification is alleviated. The medicine for preventing and treating vascular calcification is prepared on the basis of inhibition of the ACLY of vascular smooth muscle, has important clinical application potential for vascular calcification treatment, and can provide a new treatment option for patients with vascular calcification.

To reduce the psychological burden on patients caused by decision-making. [Solution] The medical information processing device comprises a reception unit, a decision unit, an extraction unit, a generation unit, and a presentation unit. The reception unit receives input of criteria for reference patients that will be used as reference for decision-making of the target patient to be treated. The decision unit selects at least one reference patient based on the criteria. The extraction unit extracts medical information related to the decision-making of the reference patient from medical information related to the treatment of multiple patients. The generation unit generates reference information based on the extracted medical information, including information representing branching points related to decision-making and the options for medical treatment at those branching points, as well as information related to the options not selected by the reference patient. The generation unit presents the generated reference information.

The application discloses a medical instrument technical field, and relates to an embryo transfer device, which comprises a sleeve, an inner core and a syringe, the inner core is detachably connected with the syringe, the tail section of the inner core is provided with a circular arc structure at an opening, the thickness of the tube wall of the opening is gradually reduced from the opening to the tail section, and the inner wall of the tube wall of the opening is provided with a funnel structure; the syringe comprises a barrel, a pressurizing barrel is connected to the barrel, the inner diameter of the inner cavity of the barrel is smaller than the inner diameter of the inner cavity of the pressurizing barrel, a piston plate is arranged in the barrel, the piston plate is in sliding fit with the inner wall of the barrel, the pressurizing barrel is in communication with the barrel, a push plate is arranged in the pressurizing barrel, a push rod is connected to one side of the push plate, and the push rod penetrates through the pressurizing barrel. The special syringe is designed, the syringe and the inner core are used in cooperation, the embryo can be better controlled in suction and injection, the damage to the endometrium is reduced, the success rate and safety of embryo transfer are improved, and better treatment options are provided for infertile patients.

The application provides application of a C1q neutralizing monoclonal antibody combined with a PD-1 monoclonal antibody in preparation of a drug for treating a solid tumor, and belongs to the technical field of biological medicine. It is found that the combination of the C1q neutralizing monoclonal antibody and the PD-1 monoclonal antibody can effectively enhance the anti-tumor effect on the solid tumor, and especially exhibits a significant synergistic inhibitory effect on the growth and metastasis of a solid tumor resistant to the PD-1 monoclonal antibody, wherein the solid tumor resistant to the PD-1 monoclonal antibody includes but is not limited to colorectal cancer, melanoma, lung adenocarcinoma and liver cancer. The application provides a new treatment option for patients resistant to the PD-1 monoclonal antibody, and has a wide clinical application prospect.

A method, computer program product, and computer system for a platform for managing injectable medication administration alerts. The platform may include: a server configured to receive administration data from an intelligent injection device, a database configured to store treatment schedules, an artificial intelligence module configured to categorize injection events based on compliance with treatment schedules, and an alerts module configured to: generate and send notifications based on injection event categorization, deliver alerts related to health, biometrics, medications and injections, provide visual and audible outputs regarding injection administration, and warn users about detected behaviors that may negatively impact treatment.

A real-time clinical AI drift detection and regulatory evidence generation system continuously monitors AI-assisted clinical workflows for deviation from validated, regulator-aligned baselines. The system classifies regulatory relevance and produces auditable post-market surveillance evidence while preserving clinician authority. Continuous regulatory readiness is achieved without autonomously diagnosing conditions or prescribing treatment actions.

The invention relates to the fields of therapy and drug delivery. It is based on an unexpected finding that a combination of an oligonucleotide-based medicament with a saponin component comprising a penta-cyclic triterpene saponin of a 12,13-dehydrooleanane aglycone core, not only does not appear to be associated with oligonucleotide medicament-induced nephrotoxic effects after systemic administration in vivo, but also that it allows the oligonucleotide-based medicament to enter and act on its nucleic acid target inside of the kidney cells instead of remaining unproductively trapped in renal subcellular compartments or being eliminated into the urine via the renal glomerular filtration system. In line with this finding, herein disclosed are therapeutic combinations, compositions, and formulations, as well as methods of treatment involving their administration, which comprise an oligonucleotide-based medicament that acts on an intracellular nucleic acid target in the kidney cells and / or in the cells of the spleen, being the other blood filtering organ in addition to the kidney, and a saponin component that enables the effective release of said medicament inside of these cells, thus allowing its use at a much lower and safer dose. The provision of the presented herein therapeutic combinations enables effective modulation of gene expression in the kidney and / or spleen cells and, therefore, it opens not only new treatment options for kidney diseases, in particular those involving inflammation and / or splenomegaly, but also for diseases of other organs which affect or are affected by the pathological processes happening in the kidneys and / or in the spleen, in particular being inflammatory processes.

1. Name of the product in this design: Digital Panel for Disease Discussion (Multifunctional). 2. Purpose of this design: This product is mainly used in hospitals or other medical institutions as a multifunctional digital support tool for doctors during patient consultations or discussions of medical conditions. Its functions include: displaying patient condition information, providing handwriting and graphic input, and generating relevant models in real time based on the discussion content and presenting them in a holographic 3D form to assist medical staff in analyzing the condition and discussing treatment plans. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

A system for computer-aided triage can include a router, a remote computing system, and a client application. A method for computer-aided triage can include determining a parameter associated with a data packet, determining a treatment option based on the parameter, and transmitting information to a device associated with a second point of care.

This utility model discloses a medical wastewater treatment device, belonging to the field of medical wastewater treatment equipment. It includes a treatment cylinder I and a treatment cylinder II. The treatment cylinder I is installed on the top of the treatment cylinder II and is reinforced by a limiting ring. It uses a combination of physical and chemical methods to treat medical wastewater, providing diverse treatment options and improving the treatment efficiency of medical wastewater. At the same time, the entire device is designed as an integrated unit, occupying a small area, which meets both wastewater treatment requirements and actual land use requirements.