58 results about "Treatment field" patented technology

The present disclosure relates to the field of nuclear imaging and therapy, and more specifically to high purity copper radiotracer compositions useful in imaging, such as positron emission tomography (PET) and single-photon emission computerized tomography (SPECT), and therapy. More specifically, the present disclosure relates to novel compositions useful in imaging and treatment of conditions such as prostate cancer, somatostatin receptor-expressing tumors, like neuroendocrine tumor, epithelial tumors, as well as to methods wherein such compositions are prepared.

A multimodal deep learning framework which is used to determine the likelihood of a particular treatment method effectively treating a patient with ovarian / kidney cancer with the goal of increasing patient survival. The framework takes into account not only large histopathology images (whole slide images), but also clinical variables to increase the scope of the data. The results demonstrate that the proposed models achieve high prediction accuracy and interpretability and can also be transferred to other cancer datasets without significant loss of performance. One of the key innovations here is the combination of pathology and clinical variables in a deep learning model to provide recommendations in therapy areas with limited information.

Systems and methods for destroying or inhibiting cancer cells and other rapidly-dividing cells including an alternating polarity (AP) magnetic field generator and one or more AP electromagnetic coil adapted to be coupled to at least a portion of a patient's body, and a controller to control the AP magnetic field generator and at least one AP electromagnetic coil and cause the field generator and coil to apply AP magnetic field having a frequency of 0.5-500 KHz and a field strength of 0.5-5 mT to the at least a portion of the patient's body area to achieve a desired inhibiting effect on cancer cells or other rapidly-dividing cells. Treatments provided by the system may be co-administered with an anti-cancer therapy such as a chemotherapy drug, a hormone therapy drug, targeted therapy drugs, immunotherapy drugs, an angiogenesis inhibitor drug, or tumor treatment field therapy.

Methods and systems for positioning and positioning a patient for irradiation therapy without fiducial markers. Platform settings including parameters of the patient support platform are obtained. Platform position data is obtained in which a patient is placed on a platform for imaging without fiducial markers, the platform position data including 3D coordinates of the platform relative to an imager coordinate system calibrated to a predefined fixed set of initialized coordinates in a treatment room. Target tissue is imaged with the patient on the platform. A treatment plan is generated based on the target tissue imaging. The treatment plan comprises a treatment radiation field of a treatment angle, and the treatment angle comprises a platform positioning parameter. When treatment is initiated, the patient is placed on the platform without fiducial markers according to the platform settings. In accordance with the treatment plan, the platform position data, and a coordinate system transformation of the imager coordinate system to the treatment room coordinate system, the platform is adjusted to position the patient at the placement position in the treatment room such that the target tissue is positioned at the isocenter of the treatment room.

1. A transducer device for delivering a tumor treatment field to a subject's body, comprising: an electrode array configured to be positioned across the subject's body with a face of the array facing the subject's body, the array including electrode elements positioned in substantially symmetrical positions centered about a center of gravity of the array; a void space located between at least one pair of adjacent electrodes of the array; and a polymeric material layer overlying the electrode array and located on a side of the array facing away from the subject's body.

The invention discloses a near-infrared photosensitizer for specifically recognizing fibroblast activation protease (FAP-alpha) as well as a preparation method and application of the near-infrared photosensitizer. A cyanine derivative is used as a fluorescent parent nucleus (ICyOH) of the photosensitizer, the fluorescence of the photosensitizer can be almost completely masked by modifying the photosensitizer, and after the photosensitizer reacts with FAP-alpha for 60 minutes, the fluorescence intensity is rapidly enhanced, so that high sensitivity, good selectivity and anti-interference performance are shown. The ZGP-LL-ICy is a photosensitizer with a cyanine structure, FAP-alpha fluorescence enhancement and high selectivity to FAP-alpha, the reagent shows high selective response to FAP-alpha enzyme, active ICyOH molecules with near-infrared fluorescence are released under the action of enzymolysis, and tumor fluorescence imaging of deep tissue penetration is achieved. Meanwhile, the activated ICyOH can generate cytotoxic active oxygen under the illumination condition, and photodynamic therapy on pancreatic cancer is achieved. The reagent has the advantages of low background fluorescence, deep tissue penetration, diagnosis and treatment integration and the like, and has important application value in the fields of early diagnosis and precise treatment of pancreatic cancer.

The application discloses a lenvatinib-polyethylene glycol coupling compound and a preparation method and application thereof. The lenvatinib-polyethylene glycol coupling compound has a structure as shown in the formula (I): in the formula (I), n is greater than or equal to 2. The application further provides a nano preparation containing vinpocetine and the lenvatinib-polyethylene glycol coupling compound and used for manufacturing drugs, which can be applied to tumor treatment, effectively improves the limitation of a single drug treatment method on tumor inhibition, and shows a positive application potential in the tumor treatment field.

1. The name of the design product: radiological imaging device. 2. The use of the design product: the design product is used in the field of medical radiation treatment to display the image of medical radiation. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1. 5. The design claimed contains color.

A therapy assembly can have an inner layer having an inner surface and an outer surface and defining a plurality of openings extending therethrough. The therapy assembly can also include a plurality of plates, each plate at least partially received within a respective opening of the plurality of openings of the inner layer. The therapy assembly can also include therapy circuitry including a cable having a plurality of electrical leads and a plurality of lead ends, each electrical lead electrically connected to a respective lead end of the plurality of lead ends. A cover layer can be attached to the outer surface of the inner layer and cover the plurality of lead ends of the cable. The plurality of lead ends can be in contact with a respective plate of the plurality of plates to define a plurality of electrodes.

The invention belongs to the technical field of medical diagnosis, and particularly relates to a visual column diagram construction method for identifying and diagnosing suppurative and tuberculous lumbar major muscle abscesses and interactive application. According to the invention, it is found that six indexes including serum uric acid (UA), thrombin time (TT), neutrophil absolute value (NEUT #), age (Age), fever (Fever) and erythrocyte sedimentation rate (ESR) are related to the type of the lumbar major muscle abscess, and a visual column diagram construction method for identifying and diagnosing suppurative and tuberculous lumbar major muscle abscess and interactive application are invented. And a first visual and quantifiable column diagram (Nomogram) prediction model for differential diagnosis of lumbar major muscle abscess is provided for the field. The technical problem that an abstract mathematical prediction model is converted into a visual graphic diagnosis tool which is intuitive in form and convenient to operate is solved, so that the visual graphic diagnosis tool can be separated from dependence on specific computing equipment, and clinical medical staff can quickly and accurately apply the visual graphic diagnosis tool on a diagnosis and treatment site conveniently.

A method for assisting in transducer placement on a subject's body to apply a tumor treating field includes determining first image data based on one or more images associated with a portion of the subject's body, the first image data including one or more transducer placement locations; determining second image data based on the one or more images, the second image data including one or more recommended transducer placement locations; registering the second image data to the first image data; and generating composite data including the one or more transducer placement locations and the one or more recommended transducer array placement locations.

The application is suitable for the medical diagnosis and treatment field, and provides an auxiliary decision-making method and system applied to ultrasonic diagnosis and treatment, a medium and medical equipment.The method comprises the following steps: in response to a selection instruction of a user, a target logical decision workflow selected by the user is loaded; whether a standardized image acquisition workflow is pre-associated with a current decision node of the target logical decision workflow is judged; if yes, the image acquisition workflow associated with the current decision node is activated; a decision option selected by the user for a judgment question of the current decision node is received, and the current decision node, the decision option and an ultrasonic image associated with the decision option are data-associated to form structured decision evidence and are stored; according to a preset logical relationship of the decision option and the target logical decision workflow, a next decision node is determined and entered until a conclusion node is reached.The application solves the problems of insufficient quality, efficiency and reliability of the existing ultrasonic diagnosis and treatment.

This document describes a system and method for administering TTFields. The system comprises an electric field generator that produces a signal with a frequency of 50 kHz to 1 MHz and is connected to an electrode. A pad, connected to the electrode, includes a continuous-phase solid material and a conductive gel. The continuous-phase solid material receives the signal from the electrode, has a surface in contact with the skin, and is made of a conductive material or has a conductive material adhered, absorbed, or adsorbed onto it. The surface in contact with the skin has cavities whose size and dimensions allow for the accommodation of a hair follicle. The conductive gel is adhered, absorbed, or adsorbed onto the surface in contact with the skin and is located within some of these cavities.

The present invention relates to a multileaf collimator and a radiotherapy machine comprising the same. A multilayer multileaf collimator (MLC) includes an outboard shielding member that spans or extends across a treatment field from a guide feature in a first leaf bank to a matching guide feature in an opposing second leaf bank. Unlike pairs of beam blocking leaves that extend to a central portion of the treatment field, each outboard shielding member extends across the treatment field from within an outer edge of one leaf bank to a corresponding outer edge of the opposing leaf bank.

Methods and systems for radiation treatment planning use objective function formulations to evaluate a proposed (candidate) radiation treatment plan, to determine whether or not clinical goals that are specified for treatment of a patient are satisfied by the plan. Dose distributions for a region of a target volume are generated. A value of an objective function formulation is determined. The value of the objective function formulation is a function of difference between a value that is based on a dose distribution and a value for a range that is associated with the treatment field corresponding to the dose distribution. In this manner, the uniformity of doses of individual treatment fields can be controlled. The value of the objective function formulation can be used in a process for optimizing dose distributions in the radiation treatment plan.

The invention relates to an automatic treatment field segmentation method for controlling a treatment time in a plan. The method comprises defining a radiation field associated with an initially defined radiation process; automatically segmenting the radiation field into a plurality of N sub-fields based on a set of criteria, wherein N > 2 and n e N, said set of criteria comprising at least a time limit associated with a duration of the radiation process for at least one of the N sub-fields; and providing a radiation beam configuration to control a radiation device adapted to provide the radiation process associated with the segmented radiation field.

The application discloses a rotational speed determination method, device and equipment, and belongs to the field of radiotherapy. The rotational speed determination method comprises the following steps: acquiring dose data and leaf data of all sub-fields corresponding to each gantry angle; determining the irradiation sequence of each sub-field corresponding to each gantry angle and the rotational speed of each rotation of the gantry according to the dose data and the leaf data.

A tumor treatment field (TT field) may be delivered to the body of the subject at a higher field intensity by turning off the overheated one or more electrode elements in the converter array. This may be accomplished by using a thermal resistor that senses the temperature of each electrode element. Partial wiring of each converter array is shared between the electrode elements and the thermal resistors by using a plurality of conductors, each of which electrically connects (a) the pins of the connectors, (b) the respective electrode elements, and (c) the respective thermal resistors. In some embodiments, all thermal resistors are wired in series. In other embodiments, all thermal resistors share a common connection.

The invention discloses a steep pulse, radio frequency and microwave all-in-one machine, and relates to the field of tumor treatment, the all-in-one machine is configured as a treatment device which selectively delivers treatment energy to target tissue in a time division multiplexing mode, and the treatment device comprises a host, a multi-mode energy generation module, an intelligent interface module and an integrated treatment head module, the host is a display-control integrated vertical operating platform, rollers are arranged on the bottom side of the host, and a central control unit, a power conversion unit, a cooling circulation unit and a plurality of independent shielding chambers are arranged on the inner side of a shell of the host; according to the steep pulse, radio frequency and microwave all-in-one machine, the multi-mode energy generation module, the intelligent consumable identification interface and the integrated multi-mode treatment head are integrated, a scheme of unified control, safety isolation and multi-mode treatment head cooperative driving is constructed, cooperative control over different energies and treatment probes can be achieved, and the treatment efficiency is improved. And particularly, the problem that multi-energy equipment is tedious in discrete operation is solved.

The invention relates to the field of boron neutron capture therapy, and discloses a method for improving the corrosion resistance of an accelerator neutron source target cooling system, which comprises the following steps: 1) forming a periodic micron-order corrugated oxide film on the surface of a non-target material layer of a copper substrate of the accelerator neutron source target cooling system by laser marking treatment; (2) an alpha-Ta film of a body-centered cubic structure grows on the surface of the oxidation film through magnetron sputtering; and after passivation, the Ta2O5 is converted into a Ta2O5 passive film. The method comprises the following steps: firstly, forming an oxide film with a special shape of periodic micron-sized corrugation on the surface of a copper substrate by utilizing laser marking treatment; an alpha-Ta film is further grown on the surface of the oxidation film through magnetron sputtering; and the copper substrate is passivated into a Ta2O5 passive film, so that the corrosion resistance of the surface of the copper substrate is greatly improved.

The present application relates to the technical field of medical equipment, and discloses a conformal wireless LIPUS erectile dysfunction treatment device based on a photoacoustic transducer, which comprises a pulsed light source emitter and a photoacoustic conversion composite material, and a use method of the treatment device, which comprises the following steps: uniformly applying the photoacoustic conversion composite material to a penis part of a patient, and allowing the photoacoustic conversion composite material to solidify to form a flexible conformal film layer; turning on the pulsed light source emitter, and irradiating the conformal film layer with far-infrared pulsed light emitted by the pulsed light source emitter; after the conformal film layer absorbs light energy of the far-infrared pulsed light, the light energy is converted into heat energy, then thermal expansion of the conformal film layer is caused, so that LIPUS is generated, and rehabilitation treatment is performed on the penis part of the patient. The present application provides a more portable, more comfortable and lower-cost LIPUS ED treatment device and method, and helps the clinical promotion and market application of LIPUS in the ED treatment field.

The invention provides a proton intensity modulated therapy radiation field direction automatic planning method, system and device based on deep learning and multi-objective optimization, and a storage medium, and the method comprises the steps: inputting a patient medical image, a tumor target region, an endangered organ structure and a treatment plan radiation field direction into a pre-trained 3DU-Net model, and obtaining a three-dimensional radiation field direction probability distribution diagram; performing Fibonacci spherical sampling to generate a candidate radiation field direction, calculating a path length score and an organ-at-risk avoidance score in each direction, and dynamically weighting and balancing the two scores; a proton range error and a patient positioning error are introduced to simulate dose distribution, target area coverage and organ-endangering dose change under the error are evaluated, and a robustness score is calculated; performing collision detection on the treatment rack, and rejecting directions which are not reachable or have collision risks; and selecting a direction to encrypt and sample near the direction, and optimizing a final radiation field direction according to comprehensive scoring results. According to the method, the radiation field direction can be automatically optimized, target dose coverage and organ-endangering protection are improved, and the robustness of a treatment plan to errors is enhanced.

The invention relates to a radiation treatment plan optimization method and equipment. The control circuitry retrieves at least one optimization factor and optimizes the radiation therapy plan by automatically selecting at least one therapy field angle based at least in part on the at least one optimization factor and a redundancy cost constraint.