110 results about "Phenanthrene" patented technology

The invention discloses a method for repairing a phenanthrene-cadmium co-polluted environment by using a biochar-based immobilized microbial inoculum, the method is characterized in that the phenanthrene-cadmium co-polluted environment is treated by using the biochar-based immobilized microbial inoculum, and the biochar-based immobilized microbial inoculum is prepared by using modified peanut shell biochar as a carrier. The modified peanut shell biochar is loaded with a phenanthrene efficient degrading flora SMP, and the phenanthrene efficient degrading flora SMP is obtained by domesticating coking plant sludge as a raw material and polycyclic aromatic hydrocarbon as a carbon source. The method has the advantages of being high in treatment efficiency, good in remediation effect, simple in process, convenient to operate, low in treatment cost and the like, phenanthrene in the soil can be effectively removed, cadmium in the soil can be effectively fixed, the use value is high, the application prospect is good, and a green and environment-friendly biological way is provided for remediation of the phenanthrene-cadmium co-polluted environment.

The invention discloses a P.megaterium strain with stress resistance, growth promotion and environmental restoration functions and application thereof, and belongs to the technical field of microorganisms. According to the present invention, the preservation number of the Pristeria megaterium XT106 provided by the invention is CCTCC (China Center For Type Culture Collection) NO: M 2025912, and the preservation number of the Pristeria megaterium XT106 provided by the invention is CCTCC NO: M 2025912; the Pristia megaterium XT106 provided by the invention is a strain capable of oxidizing manganese to form a biological manganese oxide, and the biological manganese oxide can adsorb and remove heavy metals (Cu, Sb, Pb, Zn, Cd and Cr) and degrade antibiotics (tetracycline and ciprofloxacin). The strain can move, tolerate acid-base, high-salt, phenanthrene and sulfamethoxazole environments, has the capability of generating a biological membrane, and can generate hydrogen sulfide, adsorb / fix and remove heavy metals (Cd, Pb, Zn, Sb and Cu) and promote plant growth.

The invention discloses a Pseudomonas nicosulfurones bacterial strain and an application of the Pseudomonas nicosulfurones bacterial strain in degradation of phenanthrene and benzopyrene. According to the invention, a degradation strain Pseudomonas nicosulfurensis DY-8, which takes phenanthrene and benzopyrene as carbon sources, is obtained by domestication, separation and identification from petroleum-polluted soil in Ningbo. The invention also relates to a method for preparing the degradation strain Pseudomonas nicosulfurensis DY-8 with phenanthrene and benzopyrene as carbon sources. The DY-8 can utilize phenanthrene and benzopyrene as carbon sources, and after the DY-8 is cultured in an inorganic salt culture solution with the initial concentration of phenanthrene and benzopyrene being 50 mg.L <-1 > and 25 mg.L <-1 > respectively for 7 days, the degradation rates of phenanthrene and benzopyrene can reach 70% or above. Therefore, the strain has good application potential in the aspect of bioremediation of polycyclic aromatic hydrocarbon.

The invention discloses a bone cement composition and application thereof, and relates to the technical field of bone cement. The bone cement composition comprises a solid phase component and a liquid phase component, wherein the solid phase component comprises 60-75 parts of composite calcium phosphate, 10-20 parts of strontium glass powder, 8-12 parts of a reinforcing agent and 3-7 parts of a solidification reaction regulator; the liquid phase component comprises 20-30 parts of a phosphate buffer solution, 3-8 parts of a sodium citrate solution, 5-15 parts of an anti-inflammatory agent and 1-5 parts of a hyaluronic acid solution. The preparation method comprises the following steps: reacting 1, 10-phenanthrene-2, 9-dicarboxylic acid with 2-aminomethyl furan to obtain an intermediate 1, and reacting the intermediate 1 with poly (ethylene glycol) maleimide to prepare the reinforcing agent. The prepared bone cement composition has good mechanical properties, self-repairing performance and anti-inflammatory performance, and has a good application prospect in the field of bone repairing.

A water quality analysis system is calibrated without using any organic fluorescence material such as phenanthrene. The water quality analysis system analyzes a component to be measured contained in a liquid sample by a fluorescence spectroscopy, and that comprises a light irradiation section that irradiates the liquid sample with a light having an excitation wavelength of the component to be measured, a light detection section that detects a fluorescence of the component to be measured emitted from the liquid sample, a calculation unit that calculates a concentration of the component to be measured by using a fluorescence intensity obtained by the light detection section, and a solid fluorescence reference member that is arranged on an optical path between the light irradiation section and the light detection section and that emits the fluorescence by the light from the light irradiation section at a time of calibration.

This disclosure refers to a method for the synthesis of polymers with weight average molecular weights greater than 50,000 g / mol, chemically inert, with a minimum decomposition temperature of 425° C., and a main chain composed only of carbon-carbon bonds, which contain structures of the type of naphthalene, phenanthrene, anthracene, pyrene, carbazole or any other where two or more aromatic rings of six carbon atoms of the benzene-type are fused, which may or may not contain aromatic heterocycles. In addition, the polymers obtained from the present disclosure may or may not contain fluorine atoms in their structure. The synthesis described here is carried out by means of polycondensation between a polycyclic aromatic compound and a compound with a carbonyl group in its structure in a strong acid medium.

The invention discloses a bacterial strain for reducing dissimilatory nitrate into ammonia nitrogen through anaerobic biodegradation of polycyclic aromatic hydrocarbon and application of the bacterial strain, the bacterial strain is named as PheICNA, and the bacterial strain belongs to Intraporum calvum. The strain is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.40686. The strain can degrade polycyclic aromatic hydrocarbons such as phenanthrene under anaerobic conditions and completely metabolize the polycyclic aromatic hydrocarbons into carbon dioxide. Meanwhile, nitrate radicals are reduced into ammonium nitrogen, and the generated ammonium nitrogen can be used for growth of microorganisms and can be used as a nitrogen source for plants. The strain can be used for biologically repairing polycyclic aromatic hydrocarbon pollutants such as phenanthrene in soil, can convert nitrate nitrogen in the soil into ammoniacal nitrogen at the same time, achieves the effect of nitrogen maintenance, and has good application prospects in the aspects of polluted soil treatment and the like.

The invention discloses a bacterium DY-11 for degrading phenanthrene and benzopyrene in petroleum-contaminated soil and application of the bacterium DY-11. The bacterial strain is Achromobacter expander DY-11, and the preservation number of the bacterial strain is GDMCC No: 66005. Experiments prove that the strain DY-11 can respectively utilize phenanthrene and benzopyrene as carbon sources to degrade phenanthrene and benzopyrene, and after the strain DY-11 is cultured in inorganic salt culture solutions with the initial concentration of phenanthrene and benzopyrene being 50 mg.L <-1 > and 25 mg.L <-1 > respectively for 7 days, the degradation rates of phenanthrene and benzopyrene can reach 65% or above. Therefore, the DY-11 is a strain which can degrade phenanthrene and benzopyrene and has very strong tolerance to phenanthrene and benzopyrene, has strong adaptability to polycyclic aromatic hydrocarbons, and has better application potential in the aspect of bioremediation.

The invention relates to a method for passivating a perovskite solar cell and the perovskite solar cell. A horizon passivation layer is generated after a chlorothalonil solution is passivated. The chlorothalonil with the conjugated structure has two symmetrically distributed cyano groups and four symmetrically distributed chlorine atoms, can rivet two uncoordinated Pb < 2 + > at the same time to form a Lewis acid-base pair, passivates halogen vacancies on the surface of perovskite at the same time, doubly passivates defects of a perovskite layer, and reduces non-radiative recombination. And on the other hand, a plurality of reaction sites exist between the chlorothalonil and the perovskite, so that the chlorothalonil with a rigid conjugated structure can be flatly laid on the surface of the perovskite, a transmission barrier formed after vertical close packing of a single-site passivator is avoided, and carriers can be rapidly transferred. In addition, when chlorothalonil is flatly laid on the surface of the perovskite, hydrophobic benzene rings in the molecular structure are exposed outside, gradient energy level arrangement between a perovskite layer and a carbon electrode is promoted, and therefore the photoelectric conversion efficiency and stability of the perovskite solar cell are improved.

The invention relates to the technical field of environmental remediation microorganisms, and discloses acinetobacter B2-4, a culture method thereof and application of the acinetobacter B2-4 in degradation of polycyclic aromatic hydrocarbon. The Acinetobacter sp. B2-4 is preserved in the China General Microbiological Culture Collection Center on March 3, 2025, the preservation address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC No.33689. The Acinetobacter sp. B2-4 has the advantages that the Acinetobacter sp. The Acinetobacter sp. B2-4 disclosed by the invention is an anaerobic bacterium, and can utilize nitrate, iron, sulfate and the like to replace an electron acceptor in an anoxic environment to continuously degrade polycyclic aromatic hydrocarbon. After the strain is cultured for 45 days, the degradation rate of phenanthrene reaches 74.9%, and the degradation rate of pyrene reaches 56.2%.

Disclosed herein are compositions and methods useful for the prevention, treatment, reduction, or amelioration of various diseases, disorders, or conditions. Some aspects pertain to a pharmaceutical composition comprising 17-ethynyl-10R, 13S-dimethyl 2, 3, 4, 7, 8R, 9S, 10, 11, 12, 13, 14S, 15, 16, 17-hexadecahydro-1H-cyclopenta[a]phenanthrene-3R, 7R, 17S-triol, including solid states thereof. Also presented herein is the surprising discovery that exposing a subject to the compound and / or compositions disclosed herein can prevent, treat, reduce, or ameliorate a condition related to a subject previously infected with a virus.

The group of inventions relates to the field of medicine, pharmacology and the chemical and pharmaceutical industry and includes an improved method for producing (10S, 13S, 16R, 17R)-17-hydroxy-10,13,16-trimethyl-17-propanoyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3-one (compound of formula (I)) and the use thereof for industrial batch, semi-continuous and continuous chemical production. Also described is a method for producing an intermediate compound, Vamorolone Acetate. The method for producing the compound of formula (I) is carried out according to the schema depicted. The production method makes it possible to produce the compound of formula (I) with a purity suitable for the use thereof in a finished dosage form for subjects requiring treatment for Duchenne muscular dystrophy. Thus, the technical results of the present invention consist in an improved production method which results in: a high yield and chemical purity, including stereoisomeric purity, of the compound of formula (I) and intermediate products in the synthesis of the compound of formula (I), which are suitable for use in a finished dosage form for subjects requiring treatment for Duchenne muscular dystrophy; the adaptability of the synthesis of the compound of formula (I) to industrial production; environmentally-friendly production; and a decrease in the formation of undesirable by-products.

Method for producing a flame-retardant polyester, comprising the following steps: - Reaction of a chain-forming monomer (A) with a phosphorus-containing polyester (B) and at least a difunctional alcohol (C) to form a reaction mixture, wherein the reaction is carried out at a temperature at which alcoholysis of the phosphorus-containing polyester (B) takes place, wherein the phosphorus-containing polyester (B) is obtainable by polycondensation of phosphorus-containing monomers (B1) with ester-forming monomers (B2), wherein the phosphorus-containing monomer (B1) is selected from the addition products of 9,10-dihydro-9-oxa-10-phospha-phenanthrene-10-oxide (DOPO) and core-substituted DOPO derivatives to unsaturated compounds from the group of mono- and polyvalent carboxylic acids and their anhydrides, and the ester-forming monomer (B2) is selected from the group consisting of mono- and polyhydric alcohols, mono- and polyhydric carboxylic acids and mixtures thereof, and - Producing a flame-retardant polyester from the reaction mixture, wherein the flame-retardant polyester comprises units of the chain-forming monomer (A), the phosphorus-containing polyester (B) and the at least difunctional alcohol (C).

The invention provides a flexible flame-retardant polypropylene cable material and a preparation method thereof. The soft flame-retardant polypropylene cable material is prepared from the following raw materials in parts by mass: 50 to 70 parts of modified polypropylene, 0.5 to 1.0 part of antioxidant, 0.5 to 1.0 part of ultraviolet absorbent and 2 to 5 parts of pigment, wherein the modified polypropylene is obtained by polymerizing a flame-retardant monomer, butyl acrylate and 2-ethylhexyl acrylate; the preparation method comprises the following steps: reacting 9, 10-dihydro-9-oxo-10-phosphine-phenanthrene with fumarate to generate a phosphine flame-retardant intermediate containing a phosphine oxygen group and a diester group; and then grafting the flame-retardant intermediate to a side chain of polypropylene by using a free radical initiator to obtain a high-flexibility flame-retardant polypropylene cable material, and improving the characteristics of difficult dispersion, strong rigidity and the like of DOPO as a flame retardant.

The invention discloses a nicosulfuron pseudomonas (Pseudomonas nisulfuron HD1) with a capability of degrading multiple pollutants and an application of the nicosulfuron pseudomonas (Pseudomonas nisulfuron HD1, and belongs to the technical field of screening and application of functional microorganisms. The strain is derived from a chicken manure aerobic composting environment, the preservation number is GDMCC No: 67351, and nitro polycyclic aromatic hydrocarbons, polycyclic aromatic hydrocarbons and tetracycline antibiotics can be efficiently degraded at the same time. In a single pollutant with the concentration of 50 mg / L, the degradation rates of tetracycline and doxycycline exceed 97% in 8 h, the degradation rate of nitrofluoranthene reaches 99.01% in 48 h, and the degradation rate of phenanthrene reaches 66.17%. In nitrofluoranthene-phenanthrene composite pollutants, the 48-hour degradation rate is kept to be 78% or above. The strain is high in degradation efficiency and strong in environmental adaptability, provides a new microbial resource for bioremediation of a combined pollution site, and has a wide application prospect.

The present invention relates to the technical field of organic chemistry, and discloses a preparation method of 9-phenanthrene formic acid, wherein the preparation method comprises the following steps: using phenanthrene as a main raw material, iron bromide or zinc bromide as a catalyst, reacting with hydrobromic acid and hydrogen peroxide at 20 to 50 ° C to generate 9-bromophenanthrene, 9-bromophenanthrene reacts with cyanide under a catalyst to generate 9-nitrile phenanthrene, and then hydrolyzing under alkaline conditions to obtain 9-phenanthrene formic acid. The present invention uses cheap and readily available raw materials such as phenanthrene, hydrobromic acid, hydrogen peroxide and sodium cyanide to prepare 9-phenanthrene formic acid, with low production cost, high conversion rate, good product quality, mild reaction conditions, low equipment requirements, and can be used for large-scale industrial preparation of 9-phenanthrene formic acid.

The invention discloses a Bosea thioxidans DY-5 strain and an application of the Bosea thioxidans DY-5 strain in degradation of phenanthrene and benzopyrene. The strain Bosea thioxidans DY-5 is obtained through domestication, separation and identification from petroleum-contaminated soil of Ningbo, phenanthrene and benzopyrene can be used as carbon sources, and after the strain is cultured in an inorganic salt culture solution with the initial concentration of phenanthrene and benzopyrene being 50 mg.L <-1 > and 25 mg.L <-1 > respectively for 7 days, the degradation rate of phenanthrene and benzopyrene can reach 75% or above. Therefore, the strain has good application potential in the aspect of bioremediation of polycyclic aromatic hydrocarbon.

The invention provides a polycyclic aromatic hydrocarbon deep hydrogenation catalyst and a preparation method thereof. The polycyclic aromatic hydrocarbon deep hydrogenation catalyst is a skeleton nickel alloy catalyst. The deep hydrogenation catalyst for the polycyclic aromatic hydrocarbon comprises the following components: Ni, Al, Mo, Fe and Co. The deep hydrogenation catalyst for the polycyclic aromatic hydrocarbon is high in activity, relatively mild in reaction process conditions, relatively low in required reaction temperature and reaction pressure, more thorough in hydrogenation and low in unsaturated hydride content in a hydrogenation product. For hydrogenation of polycyclic aromatic hydrocarbon phenanthrene with the highest hydrogenation difficulty in the embodiment of the invention, under the conditions that the reaction temperature is 210 DEG C and the reaction pressure is 2.0 Mpa, the hydrogenation conversion rate is greater than or equal to 99.95%, and the content of unsaturated hydrophenanthrene in the product is lower than 0.1%; however, in the prior art, under the harsh conditions that the reaction temperature is 260 DEG C and the reaction pressure is 4 MPa, the product still contains about 0.51% of unsaturated hydrophenanthrene.

The utility model belongs to the technical field of deep processing of coal tar, and particularly relates to a decrystallized anthracene oil production system which comprises a main decrystallized anthracene oil tank, and a main feeding pipe, a main discharging pipe and a main discharging pump which are arranged on the main decrystallized anthracene oil tank, the auxiliary feeding pipe, the auxiliary discharging pipe and the auxiliary discharging pump are arranged on the auxiliary anthracene removal tank; and the mixing tank is connected with outlets of the main feeding pipe and the auxiliary discharging pipe. Cooling, crystallizing and centrifugally separating anthracene oil extracted from the bottom of the tar rectifying tower to obtain decrystallized anthracene oil and crude anthracene; and removing anthracene, phenanthrene, carbazole and the like in the crude anthracene through subsequent refining to obtain heteroanthracene-removed oil. Generally, the viscosity of impurity-removed anthracene oil is large, the viscosity of de-crystallized anthracene oil is small, the impurity-removed anthracene oil and the de-crystallized anthracene oil are conveyed into a mixing tank through a main discharging pipe and an auxiliary discharging pipe respectively and mixed in the mixing tank, and the feeding amount of the impurity-removed anthracene oil and the feeding amount of the de-crystallized anthracene oil are adjusted by adjusting the flow of a main discharging pump and the flow of an auxiliary discharging pump, so that the viscosity of mixed liquid (mixed anthracene oil) in the mixing tank is adjusted; therefore, the viscosity requirements for different purposes can be met.

This invention discloses a method for enhancing the degradation of adsorbed phenanthrene on biochar by sphingosine-containing bacteria. The method includes the following steps: 1) mixing sphingosine-containing bacteria solution with phenanthrene-adsorbed biochar in a culture medium solution; 2) adding an exogenous iron chelating agent and a ferric salt solution to the mixture, and then incubating under natural conditions to degrade and remove the phenanthrene adsorbed on the biochar. This invention uses an exogenous iron chelating agent and ferric salt to enhance the degradation efficiency of microorganisms on adsorbed phenanthrene on biochar, strengthens the regeneration of biochar adsorption performance through microbial degradation, improves the long-term effectiveness of biochar in soil pollution fixation and control, reduces the risk of secondary pollution, and provides technical support for improving soil environmental quality. It has good economic and environmental benefits in practical applications.

A method for preparing functional bacterial colonies for carbon fixation and decontamination of organically contaminated soil is provided. The preparation of functional bacterial colonies involves the following steps: S1, culturing the first strain: obtaining single bacteria of Sphingobium sp. RS2; S2, culturing the second strain: obtaining single bacteria of Nitrososphaera viennensis EN76; S3, quantifying the cell count; S4, mixing the single bacteria: mixing the single bacteria of Sphingobium sp. RS2 and the single bacteria of Nitrososphaera viennensis EN76 at a cell count ratio of 1:1 to obtain functional bacterial colonies. [Effects] The obtained functional bacterial colonies are easy to cultivate, easy to formulate, and easy to operate. They can not only purify phenanthrene-contaminated agricultural soil and reduce the threat to agricultural product safety, but also fix CO2 and increase the SOC content in agricultural soil.

The invention relates to the field of organic pollution wastewater treatment, and particularly discloses a preparation method and application of modified composite algae-based biochar. The method comprises the following steps: (1) collecting two green algae raw materials, centrifuging, drying, grinding, screening and filtering to obtain dehydrated algae powder; (2) mixing the two kinds of algae powder according to a ratio, fully dipping by using a zinc chloride solution, further drying, carbonizing and activating under the protection of nitrogen to obtain activated modified composite algae-based biochar; and (3) washing the activated biochar material with diluted hydrochloric acid to remove impurities, performing high-temperature pyrolysis activation again, cooling, washing, drying, and sieving to obtain the final composite algae-based biochar. The raw materials are wide in source, the green algae enteromorpha is algae bloom algae species, and the purpose of treating waste with waste is achieved; the preparation process of the material is simple and controllable, easy to industrialize and relatively low in cost; the obtained product has mild adsorption experiment reaction conditions on organic pollution phenanthrene in water, and has excellent removal effect and regeneration capacity.

The application relates to a phenanthrene-containing organic electroluminescent material and a preparation method, application and light-emitting device thereof. The phenanthrene-containing organic electroluminescent material provided by the application takes phenanthrenebenzofuran and anthracene as basic structural units, can be used as a host material of a blue fluorescent light-emitting layer, has a high glass transition temperature, high quantum efficiency, good electron transmission capacity, good film-forming property and stable property, shows high light-emitting efficiency and stability in a blue light-emitting device, and is an ideal blue fluorescent material.

The present invention provides a virtual template polycyclic aromatic hydrocarbon molecular imprinting material and its preparation method and application, first, using a molecule with a similar structure to polycyclic aromatic hydrocarbons as a virtual template, the virtual template molecule is selected from 2,3-naphthalene diol, 2-phenanthranol, 9-anthracene alcohol or one or more deuterated pyrene, polycyclic aromatic hydrocarbons are selected from naphthalene, phenanthrene, anthracene or pyrene. One or more, can imprint polycyclic aromatic hydrocarbons that are not suitable as template molecules, thereby expanding the application range of molecular imprinting technology. Secondly, the synthesized virtual template polycyclic aromatic hydrocarbon molecular imprinting polymer is used to adsorb polycyclic aromatic hydrocarbons, and has a very high selective adsorption effect on polycyclic aromatic hydrocarbons, and has a high adsorption capacity. The preparation method of the present invention is simple and reliable, has low cost, is strong in resistance to environmental matrix interference, and has broad application prospects in water pollution remediation.

The present invention relates to the field of coating technology, and discloses a kind of hydrophobic antifouling coating and preparation method thereof, the hydrophobic antifouling coating of the present invention includes 100 parts by weight of polyurethane emulsion, 30-50 parts by weight of modified titanium dioxide, 0.7-1.2 parts by weight of defoamer;Styrene-based functional monomer and KH570 modified titanium dioxide are subjected to graft polymerization reaction, hydrophobic hydrogenated phenanthrene ring condensed ring and polystyrene molecular chain are introduced on titanium dioxide surface, added to polyurethane, significantly improve the hydrophobicity of paint film.And nano titanium dioxide is after modification, dispersibility becomes better, is evenly dispersed in polyurethane paint film, forms micro-nano convex structure on paint film surface, makes paint film show super hydrophobic characteristic under synergistic effect, and water absorption is very low, is conducive to improving the waterproof and antifouling performance of coating.

The invention provides a residual oil hydrocracking conversion degree evaluation method, which comprises: 1, determining the content of a characteristic compound in an aromatic hydrocarbon component in a residual oil raw material, and recording the content as D; 2, carrying out a hydrocracking reaction on the residual oil raw material to obtain a hydrocracking liquid product, determining the content of the characteristic compound in the aromatic hydrocarbon component in the hydrocracking liquid product by using the same method as the step 1, and recording the content as E; 3, the residual oil hydrocracking conversion degree is determined according to the E / D value, and the larger the E / D value is, the higher the residual oil hydrocracking conversion degree is; wherein the characteristic compounds are benzene, naphthalene, phenanthrene, dibenzothiophene and alkyl substitutes thereof. The selected characteristic compound has good representativeness, the chromatographic analysis result of the characteristic compound is easy to identify and process, the proposed parameters and the conversion degree of the residual oil have good relevance, and the method has good operability.

The application provides a degrading bacteria agent for alkane and polycyclic aromatic hydrocarbon in high-salt water body and application thereof. The bacteria agent contains Bacillus thuringiensis NH26 strain, and is prepared by activating, fermentation culture, bacteria body collection, suspension preparation and freeze-drying of the NH26 strain. The Bacillus thuringiensis NH26 bacteria agent prepared by the application has excellent degradation capacity for alkane and polycyclic aromatic hydrocarbon, for example, the total degradation rate of 20 g / L diesel oil is 90.2%, and the total degradation rate of 50 g / L diesel oil is 84.8%. In addition, the degrading bacteria agent of the application also has strong degradation capacity for polycyclic aromatic hydrocarbon in seawater, for example, the removal rate of 50 mg / L phenanthrene in seawater is 68.56%, and the removal rate of 100 mg / L phenanthrene is 63.47%, so that the bacteria agent of the application can be applied to repair high-salt water body polluted by alkane and polycyclic aromatic hydrocarbon.

This invention discloses a strain of *Pseudomonas nicosulfuron-methyl* capable of degrading multiple pollutants. Pseudomonas nicosulfuronedens HD1 and its applications belong to the field of functional microbial screening and application technology. This strain, originating from an aerobic composting environment of chicken manure (accession number GDMCC No:67351), can simultaneously and efficiently degrade nitropolycyclic aromatic hydrocarbons (NPH), polycyclic aromatic hydrocarbons (PAHs), and tetracycline antibiotics. In single pollutants at a concentration of 50 mg / L, the degradation rates of tetracycline and doxycycline exceeded 97% after 8 hours; the degradation rate of nitrofluoranthene reached 99.01% after 48 hours; and the degradation rate of phenanthrene reached 66.17%. In nitrofluoranthene-phenanthrene composite pollutants, the degradation rate remained above 78% after 48 hours. This strain exhibits high degradation efficiency and strong environmental adaptability, providing a new microbial resource for the bioremediation of multi-contaminated sites and possessing broad application prospects.

Disclosed herein are compositions and methods useful for reducing biological age measured by DNA methylation and the treatment or amelioration of various diseases, disorders, or conditions promoted by increased biological age. Some aspects pertain to a pharmaceutical composition comprising 17-ethynyl-10R, 13S-dimethyl 2, 3, 4, 7, 8R, 9S, 10, 11, 12, 13, 14S, 15, 16, 17-hexadecahydro-1H-cyclopenta[a]phenanthrene-3R, 7R, 17S-triol, including solid states thereof. Also presented herein is the surprising discovery that exposing a subject to the compositions disclosed herein can treat, reduce, or ameliorate a condition related to biological clocks.

The application belongs to the technical field of organic contaminated soil remediation, and discloses a method for remediation of polycyclic aromatic hydrocarbon contaminated soil by sodium cyclodextrin activated persulfate. In view of the problems of poor mass transfer of reagents, low reagent utilization rate and poor remediation effect when the persulfate oxidation technology is used to remediate polycyclic aromatic hydrocarbon contaminated soil, a sodium cyclodextrin with the functions of catalytic activation and improvement of the availability of polycyclic aromatic hydrocarbons in contaminated soil is provided, and a method for remediation of polycyclic aromatic hydrocarbon contaminated soil by using the sodium cyclodextrin to activate persulfate is provided. Under the same conditions, the first-order degradation rate of HPCD sodium salt / PS to phenanthrene is 3.03 times, 3.62 times, 7.24 times and 11.71 times that of NaOH-HPCD / PS, NaOH / PS, HPCD / PS and PS system to phenanthrene, respectively. The method has the advantages of high reagent utilization rate, low remediation cost and low environmental risk, and has a wide application prospect in the remediation of polycyclic aromatic hydrocarbon contaminated soil.