548 results about "Mercaptopropionic acid" patented technology

The invention discloses a method for preparing high-purity sugammadex. The product purity is greater than 98%, the method comprises the following steps: 1) 6-deoxy-6-perhalogeno-gamma-cyclodextrin, mercaptopropionic acid and an alkalescence reagent are reacted at a certain reaction temperature in a reaction solvent to obtain a crude product sugammadex; and 2) re-crystallizing the crude product in the above step and purifying to obtain the sugammadex with purity greater than more than 98%. The method has the advantages of short synthesis step, simple technology and high security , high product quality, and large scale production.

The invention discloses a compound semiconductor photocatalyst, a preparation method of the compound semiconductor photocatalyst, a photocatalytic system comprising the compound semiconductor photocatalyst, and a hydrogen preparation method. According to the invention, quantum dots are adsorbed on the surface of TiO2 as a carrier by mercaptopropionic acid on surfaces of the quantum dots; a Co, Ni or Fe salt or its complex is assembled to the surfaces of the quantum dots in a photic driving in-situ growth way in the presence of biomass derivatives so that the compound semiconductor photocatalyst is obtained; and simultaneously, the biomass derivatives are reformed and hydrogen is produced. The preparation method of the compound semiconductor photocatalyst fast and simply realizes TiO2 sensitization by CdTe, CdSe or CdS, and realizes preparation of the compound semiconductor photocatalyst having high efficiency under visible light driving. The hydrogen preparation method realizes biomass derivative reforming and hydrogen preparation. The preparation method of the compound semiconductor photocatalyst does not need a template or an initiator. The compound semiconductor photocatalyst is efficient, stable and cheap and does not need further separation purification. According to the invention, harsh conditions such as calcining are not needed and precious metals such as Pt and Rh as cocatalysts are not adopted; reactions are efficient; operation is simple; and a cost is low and practicability is obtained.

The invention relates to a method for simultaneously detecting a divalent mercury ion and a silver ion in water solution based on fluorescence resonance energy transfer, belonging to the field of heavy metal ion detecting technology. The method comprises the following steps: firstly, preparing a detecting probe, comprising following steps: (1), preparing a cadmium telluride (CdTe) quantum dot which is encapsulated by mercaptopropionic acid (MPA); (2), designing and composing a nucleic acid probe for detection; (3), preparing a fluorescent probe CdTe-DNA of quantum dots and nucleic acid; and secondly, detecting heavy metal ion Ag+ and/or Hg2+. The method provided by the invention can detect two ions simultaneously, the workload is low, the cost is low and the process is not complex.

The invention relates to a star polycarboxylic-acid high-performance water reducing agent which is prepared by the following steps: reacting 3.2-5% of maleic anhydride and 1.2-2% of glycerol to generate a star monomer, and polymerizing the start monomer with 26-32% of methylallylpolyether, 2.4-3% of acrylic acid, 0.4-0.8% of sodium methylallyl sulfonate and other monomers in a water solution under the actions of ammonium persulfate and mercaptopropionic acid. Compared with the prior art, the star polycarboxylic-acid high-performance water reducing agent provided by the invention overcomes thedefects of high doping amount, high slump loss, poor cement adaptability and the like in the existing water reducing agent. Besides, the invention does not use any organic solvent, is simple to operate, can easily control the reaction process, and is green and environment-friendly.

There is disclosed a method of patterning an article (10) including a layer (12) of copper formed onto an insulating substrate (11) using a positive microcontact printing (MCP) process. In a preferred embodiment where the metal is copper (Cu) and the substrate is a silicon wafer, the method includes removing the native oxide presents on the Cu in a solution of HCl. Then, a stamp (13′) having a patterned polydimethylsiloxane (PDMS) body (14) is linked with a 0.2 mM solution of pentaerythritol-tetrakis(3-mercaptopropionate) (PTMP) in ethanol for 1 min, to form the inking layer (15′). The stamp is applied on the Cu layer to print a first self-assembled monolayer (SAM) (16′) according to a desired pattern. The article is dipped in a solution of ECT which is then adsorbed only in the non printed regions, forming a second SAM (18) in a configuration that is complementary to the desired pattern. Finally, the printed areas of the Cu layer are removed using a peroxodisulfate etch bath.

The invention discloses fluorescent wide chroma test paper for visually detecting copper ions as well as a preparation method and application of the test paper. The preparation method comprises the following steps: by taking a three-color ratio fluorescence probe as ink and taking filter paper as a solid-phase carrier through an inkjet printer, uniformly printing, thereby obtaining the test paper capable of visually detecting the copper ions, wherein the three-color ratio fluorescence probe refers to blue carbon dots, green quantum dots and red quantum dots, and the quantum dots are all modified by 3-mercaptopropionic acid. The three-color ratio fluorescence test paper is constructed to be used for visually detecting the copper ions by utilizing double-quenching principle first, the prepared detection test paper has the advantage that the color change range is wide compared with the conventional double-ratio fluorescence test paper, and along with addition of the detection object, test paper colors can be obviously identified by naked eyes from light scarlet, light flesh color, deep orange, grass green, dark olive green, slate blue, royalblue to cyanic color (Figure 4).

The invention relates to an early-strength polycarboxylate type high-performance water reducing agent and a preparation method. The early-strength polycarboxylate type high-performance water reducing agent is prepared from methyl allyl polyethenoxy ether, acrylic acid, maleic anhydride, 2-acrylamide-2-methyl propane sulfonic acid, sodium methallyl sulfonate, hydrogen peroxide, ammonium persulfate, L-ascorbic acid, dihydrate sodium formaldehyde sulfoxylate, mercaptoacetic acid, mercaptopropionic acid, sodium hydroxide and water. The newly-stirred concrete added with the water reducing agent has good workability; the water reducing rate can reach 30 percent or more; the 1d pressure-resistant intensity of the concrete can reach 185 percent to 198 percent; the 3d pressure-resistant intensity ratio can reach 176 percent to 187 percent; the concrete setting time is obviously shortened; the early strength of the concrete can be obviously improved; the rustiness effect on steel bars does not exist; no alkali-aggregate reaction occurs; a series of advantages such as concrete structure durability are practically guaranteed; the market prospects are wide. The product is widely applicable to various stages of commodity concrete and high-quality concrete for high-speed railways, high-speed highways, large-scale bridges, prefabricated components, airports, port buildings and the like, and is particularly suitable for being used for various concrete engineering constructions with the early strength requirements and concrete construction in low-temperature environment.

A process for preparing the nano CdTe crystal with high photoluminescent efficiency by hydrothermal technique includes preparing the precursor solution of water-soluble CdTe from CdCl2, NaHTe and mercaptoacetic acid or mercaptopropionic acid or mercaptoglycerine, and crystallizing growth of said solution in stainless steel reactor by heating to 100-200 deg.C, different temps can lead to differentcolors.

The invention discloses a polycarboxylic acid water retention agent, and a preparation method and application thereof. The water retention agent is prepared from polyether, acrylic acid, vitamin C, mercaptopropionic acid, ammonium persulfate and hydrogen peroxide. The process mainly improves the pore distribution of the concrete against the participation of the water retention agent, thereby increasing the concrete compactness, keeping the internal water of the concrete and accelerating the later hydration effect of the cementing material. All the agents are sequentially mixed according to different functions and react under certain conditions. The formula is only against the water retention agent with local material characteristics. The product has the advantages of improved local material applicability of the additives, wider application range, favorable effect and obvious cost advantage.

The invention discloses a method for water-phase microwave preparation of CdSeS quantum dots. The method provided by the invention comprises the following steps of 1, preparing a selenosulfate solution through the reaction of selenium powder and a sodium sulfite solution, 2, weighing cadmium chloride crystals, and carrying out dissolution and volume metering by deionized water to obtain a cadmium chloride solution, 3, adding a certain amount of mercaptopropionic acid into the cadmium chloride solution, 4, adjusting a pH value of the mixed solution obtained by the step 3 to a specific pH value by a sodium hydroxide solution, 5, feeding inert gas into the mixed solution having the specific pH value to remove oxygen, and adding the selenosulfate solution obtained by the step 1 into the oxygen-free mixed solution, 6, loading the mixed solution obtained by the step 5 into a teflon-made digestion tank, and heating for a reaction by a microwave digestion furnace, and 7, cooling the reaction products obtained by the step 6 to a room temperature, adding isopropanol into the cooled reaction products, carrying out purification, and drying by a freezer dryer to obtain solid powder of the CdSeS quantum dots. The method provided by the invention is fast and simple, has easily controllable technological parameters, has a low cost, realizes small sizes and even size distribution of the CdSeS quantum dots obtained by the method, and has a high fluorescent quantum yield. The CdSeS quantum dots obtained by the method can be utilized as a biological fluorescent label material through coupling with biomolecules and can also be utilized for metal ion detection.

The invention discloses a method for preparing water-soluble cadmium telluride (CdTe) quantum dots, and belongs to the field of nano-technology preparation. In the method, sodium tellurite serves as a tellurium source; cadmium chloride serves as a cadmium source; mercaptopropionic acid serves as a coordination agent; sodium hexametaphosphate serves as an auxiliary stabilizing agent; and the water-soluble CdTe quantum dots are prepared by only one step of reducing the sodium tellurite by using hydrazine hydrate in an aqueous phase system. The method has the characteristics of simple and practical operation, mild condition and low toxicity; and quantum dots with different sizes and emission wavelengths can be obtained by a method for controlling a reaction time.

The invention discloses the production method and use for imidacloprid artificial hapten, artificial antigen and specific antibody, wherein the production method comprises, using imidacloprid (1-(6-chlorine-3-picolyl)-N-nitro-2-imidazoline imine) as raw material for reaction with 3-mercaptopropionic acid under alkaline condition, thus synthesizing hapten 1-(6-(2-carboxyethyl) sulfo-3-picolyl)-N-nitro-2-imidazoline imines (IM), then coupling with proteins through carbodiimide method and mixed anhydride method to prepare artificial antigens (immunogens and peridium antigens).

The invention relates to a preparation method of an aqueous phase non-toxic white light quantum with a multilayer core-shell structure. The preparation method comprises the following specific steps: (a) preparing a shell layer material Zn+mercaptopropionic acid (MPA)+thioacetamide (TAA): taking Zn(NO3)2 and adding the Zn(NO3)2 into a conical flask filled with deionized water, taking the MPA by using a miniature liquid-transferring gun; adding the TAA into the solution; fully stirring the solution and then adjusting the pH value of the mixed solution by using NaOH; and fully stirring the solution for later use; (b) adding the deionixed water, manganese chloride and the MPA in a three-necked bottle, adjusting the pH value and then introducing nitrogen gas and removing air in the three-necked bottle by using high-purity nitrogen gas; injecting sodium hydrogen selenide by using an injector and then allowing the manganese chloride and the sodium hydrogen selenide to be fully acted to form a selenide-rich MnSe quantum dot; then injecting zinc nitrate and growing for one hour; injecting the shell layer material in the step (a) and growing; then adding a copper chloride solution and growing; adding the shell layer material; and finally, regrowing to obtain the required white light quantum dot. The white light quantum dot synchronized by the preparation method is better in water solubility and stability and has broad application prospect.

The invention discloses a preparation method for an anti-mud-type polycarboxylic-acid water-reducing agent and application thereof. The method is used to improve production efficiency of the anti-mud-type polycarboxylic-acid water-reducing agent, save energy and reinforce anti-mud performance and gradual plasticity-maintaining property of the anti-mud-type polycarboxylic-acid water-reducing agent. The preparation method for the anti-mud-type polycarboxylic-acid water-reducing agent provided by the invention comprises the following steps: under the normal temperature condition of 5 to 35 DEG C, mixing isobutylene alcohol polyoxyethylene ether and maleic anhydride-beta-cyclodextrin and then dissolving the mixture in water; adding a mixed solution of acrylic acid and p-styryl formate; adding hydrogen peroxide; under the protection of nitrogen, adding a mixed solution of mercaptopropionic acid and ascorbic acid, a mixed solution of acylic acid and p-styryl formate, and sodium dithionite; and adding an aqueous sodium hydroxide solution and adjusting the pH value to 6 to 7 so as to obtain the anti-mud-type polycarboxylic-acid water-reducing agent. The anti-mud-type polycarboxylic-acid water-reducing agent provided by the invention has a cup-shaped structure.

The invention discloses a slow-release type polycarboxylate water reducer, and a preparation method and an application method thereof. The water reducer comprises, in parts by weight, 100 parts of unsaturated polyether DD-417, 6-9 parts of acrylic acid, 0-1.80 parts of methacrylic acid, 9.50-19.50 parts of hydroxyethyl acrylate, 0-5.40 parts of hydroxypropyl acrylate, 0.90-1.10 parts of hydrogen peroxide, 0.20-0.40 part of L-ascorbic acid, 0.55-0.95 part of thioglycolic acid, 0.05-0.45 part of mercaptopropionic acid, 0-8 parts of sodium hydroxide and 185-205 parts of water. The water reducer provided by the invention helps to realize slow release, is good in fluidity maintenance property, can satisfy the relatively high requirements on slump maintenance property during engineering, has the advantages of being low in raw material cost, good in properties, obtained by one-step polymerization and the like, is applicable to construction engineering such as high-rise buildings, wide-span bridges, sea drilling platforms, tunnels, dams, airports and the like which require high slump maintenance property.

The invention discloses a phosphorus-nitrogen containing halogen-free flame-retardant hyperbranched epoxy resin and a preparation method thereof. The preparation method for the phosphorus-nitrogen containing halogen-free flame-retardant hyperbranched epoxy resin comprises the steps: firstly, enabling 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide, itaconic anhydride, polyol amine and trimethylolpropane to react with one another under an effect of an acidic ionic liquid catalyst to obtain hydroxyl-terminated hyperbranched polyester-amide; and enabling hydroxyl-terminated hyperbranched polyester-amide to react with mercaptoacetic acid or mercaptopropionic acid and allyl glycidyl ether in sequence to obtain the phosphorus-nitrogen containing halogen-free flame-retardant hyperbranched epoxy resin. The phosphorus-nitrogen containing halogen-free flame-retardant hyperbranched epoxy resin and the preparation method thereof, disclosed by the invention, have the advantages of simple process, narrow intermediate product molecular weight distribution, higher purity, good enhancing, toughening and flame retardant functions of the final product and wide application prospect.

The present invention provides a process for the preparation of sugammadex sodium involving the step of: reacting 6-perdeoxy-6-per-halo-gamma-cyclodextrin with 3-mercapto propionic acid in the presence of alkali metal alkoxide in an organic solvents. The invention also provides a process for purifying the sugammadex or its pharmaceutically acceptable salts using water and organic solvents.

The invention relates to a CdTe/CdS/SiO2 composite fluorescent nanoparticle of high quantum yield and small particle size and its preparation method. The method comprises the steps of: first preparing a cadmium telluride (CdTe) quantum dot in a water phase with mercaptopropionic acid as the stabilizing agent, then packing the CdTe quantum dot with cadmium sulfide (CdS) in the water phase so as to form a thin protective layer and remedy the surface defect of the CdTe quantum dot and optimize the quantum dot crystal form by CdS, and then, slowing down the hydrolysis speed of tetraethyl orthosilicate at a low temperature by a low-temperature high-pressure inverse microemulsion method, and controlling the compactness of SiO2 shell, so as to obtain the CdTe/CdS/SiO2 composite fluorescent nanoparticle with small particle size and high quantum yield. By changing different oil-water ratio, surfactant type and input, as well as the technology of low-temperature high-pressure hydrolysis, etc., the particle size (20-50nm) and quantum yield (20-30%) of the obtained composite fluorescent nanoparticle can be controlled.

The invention discloses a preparation method for a polyphosphate water-reducing agent. The preparation method is characterized by comprising the following steps: subjecting isoamylenol polyoxyethylene ether and pyrophosphoric acid to a phosphate esterification reaction so as to obtain isoamylenol polyoxyethylene ether phosphate monomer; and then with ammonium persulfate as an initiator and mercaptopropionic acid as a conditioning agent, carrying out free radical homopolymerization in an aqueous solution so as to obtain the polyphosphate water-reducing agent. The preparation method is simple; a single, cheap and low-cost raw material is used in the method; and the obtained polyphosphate water-reducing agent is nonvolatile and basically nontoxic, and has good biodegradability, a water-reducing rate and slump loss resistance.

The invention discloses a polycarboxylic acid-series water reducing agent with ultrahigh water absorbing capacity and a preparation method and a use method thereof, belonging to the technical field of building materials. The water reducing agent consists of the following raw materials in parts by weight: 100 parts of unsaturated polyether (I), 10-18 parts of acrylic acid, 1-3 parts of acrylamide,1.25-9.25 parts of aconitic acid, 0.45-2.25 parts of hydrogen peroxide, 0.15-0.75 part of L-ascorbic acid, 0.12-0.48 part of mercaptoacetic acid, 0.12-0.48 part of mercaptopropionic acid, 6-10 parts of sodium hydrate and 125-195 parts of water. The invention provides a polycarboxylic acid-series water reducing agent having the advantages of simple process, convenience for operating, low raw material cost and ultrahigh water absorbing capacity, a preparation method and a use method. Self-made unsaturated polyether (I) DD-405 is used for replacing methyl allyl polyethenoxy ether, so that the raw material supply market of the polycarboxylic acid-series water reducing agent is expanded, raw material cost is reduced, and raw material price is stabilized. The polycarboxylic acid-series water reducing agent is suitable for construction projects of high-rise buildings, large-span bridges, marine drilling platforms, tunnels, dams and airports.

The invention discloses a preparation method of solid phase peptide synthesis atosiban which includes the following steps: taking Rink Amide resins, Rink Amide MBHA resins or Rink Amide AM resins as starting materials and taking Fmoc amino acids as monomers, amino acids are grafted one by one and mercaptopropionic acids (Map(SX)) are protected by the last peptide chain; after protected nonapeptide resins are obtained, the acellular side-chain protective groups and cutting peptides are synchronized; then cutting peptides is carried out, and reduced crude atosiban is collected; the pH value is adjusted to 7.5 to 10.0, and oxidized crude atosiban is collected; target products are obtained by the separation and purification by preparative HPLC(C18 or C8 column). The preparation method is convenient in material source, simplifies technology and reduces cost; and the preparation method is low in the pollution of three wastes and is high in yield, and the preparation method is convenient for being industrialized and has good industrialization prospect.

The invention discloses a quantum dot-photon crystal composite film synthesis method, which specifically comprises: synthesizing cadmium telluride quantum dots through an aqueous solution synthesis method by using tellurium powder, sodium borohydride and cadmium chloride as raw materials and using mercaptopropionic acid as a stabilizer, preparing quantum dot materials having various colors and covering whole color band by controlling a reaction time, preparing silica microspheres through a stober method, preparing a photon crystal film through a vertical sedimentation self-assembly method, and repeatedly adding the quantum dots onto the photon crystal film in a dropwise manner to prepare the quantum dot-photon crystal composite film. Compared to the quantum dot film, the prepared quantum dot-photon crystal composite film of the present invention has the following advantage that the quantum dot material generates heat when the quantum dot material emits fluorescence due to the three-dimensional gap structure of the photon crystal in the case of the same amount of the quantum dot material so as to substantially improve the heat exchange efficiency with the outside, such that the fluorescence intensity is increased.