7949results about How to "High molecular weight" patented technology

A water soluble biodegradable ABA- or BAB-type triblock polymer is disclosed that is made up of a major amount of a hydrophobic polymer made of a poly(lactide-co-glycolide) copolymer or poly(lactide) polymer as the A-blocks and a minor amount of a hydrophilic polyethylene glycol polymer B-block, having an overall weight average molecular weight of between about 2000 and 4990, and that possesses reverse thermal gelation properties. Effective concentrations of the triblock polymer and a drug may be uniformly contained in an aqueous phase to form a drug delivery composition. At temperatures below the gelation temperature of the triblock polymer the composition is a liquid and at temperatures at or above the gelation temperature the composition is a gel or semi-solid. The composition may be administered to a warm-blooded animal as a liquid by parenteral, ocular, topical, inhalation, transdermal, vaginal, transurethral, rectal, nasal, oral, pulmonary or aural delivery means and is a gel at body temperature. The composition may also be administered as a gel. The drug is released at a controlled rate from the gel which biodegrades into non-toxic products. The release rate of the drug may be adjusted by changing various parameters such as hydrophobic/hydrophilic componenet content, polymer concentration, molecular weight and polydispersity of the triblock polymer. Because the triblock polymer is amphiphilic, it functions to increase the solubility and/or stability of drugs in the composition.

Novel modified exendins and exendin agonist analogs having an exendin or exendin agonist analog linked to one or more polyethylene glycol polymers, for example, and related formulations and dosages and methods of administration thereof are provided. These modified exendins and exendin agonist analogs, compositions and methods are useful in treating diabetes and conditions that would be benefited by lowering plasma glucose or delaying and/or slowing gastric emptying or inhibiting food intake.

An extrusion-based freeform fabrication method for making a three-dimensional object from a design created on a computer, including (a) providing a support member; (b) operating a dispensing head having at least one dispensing nozzle with a discharge orifice for dispensing continuous strands of a material composition in a fluent state at a first temperature onto the support member, the material composition including a reactive prepolymer with a melting point above 23° C. and the first temperature being greater than the prepolymer melting point; (c) operating material treatment devices for causing the dispensed strands of material composition to rapidly achieve a rigid state in which the material composition is substantially solidified to build up the 3-D object, the material treatment devices also working to convert the reactive prepolymer to a higher molecular weight thermoplastic resin; and (d) operating control devices for generating control signals in response to coordinates of the object design to control the movement of the dispensing nozzle relative to the support member and for controlling the strand dispensing of the material composition to construct the 3-D object.

This invention relates to antireflective coatings comprising polymeric polyoxyalkylenated colorants. More particularly, the present invention relates to antireflective coatings for utilization in forming thin layers between reflective substrates and photoresist coatings. Such antireflective coatings are very useful and beneficial within the production and fabrication of semiconductors through photolithographic procedures due to the liquid, non-crystallizing nature of polyoxyalkylenated colorants, and the lack of potentially damaging counterions, metals, and/or electrolytes within the inventive antireflective colored coatings. The inventive coatings may also be applied on lenses, mirrors, and other optical components. Methods of forming such antireflective coatings are also contemplated within this invention.

According to the present invent, effervescent granules having a controllable rate of effervescence are provided. Such granules comprise an acidic agent, an alkaline agent, a hot-melt extrudable binder capable of forming a eutectic mixture with the acidic agent and, optionally, a plasticizer. The effervescent granules are made by a hot-melt extrusion process.

It was found that the addition of polymers to viscoelastic surfactant base system allows to adjust the rheological properties of the base fluid. Depending in particular on one side of the ratio of the concentration of added polymer and the concentration of viscoelastic surfactant and on the other side of the molecular weight of the added polymer, the same polymer—or the same type of polymer—may perform different functions such as viscosity enhancer, viscosity breaker or viscosity-recovery enhancer.

The invention provides chain extenders made from epoxy-functional (meth)acrylic monomers and styrenic and/or (meth)acrylic monomers. The invention further provides polymeric compositions made from the chain extenders and plastic articles made from the compositions. Finally, the invention provides methods of using the chain extenders to improve the properties of virgin, recycled, and reprocessed condensation polymers.

Poly(β-amino esters) prepared from the conjugate addition of bis(secondary amines) or primary amines to a bis(acrylate ester) are described. Methods of preparing these polymers from commercially available starting materials are also provided. These tertiary amine-containing polymers are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the poly(amine) nature of these polymers, they are particularly suited for the delivery of polynucleotides. Nanoparticles containing polymer/polynucleotide complexes have been prepared. The inventive polymers may also be used to encapsulate other agents to be delivered. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. A system for preparing and screening polymers in parallel using semi-automated robotic fluid delivery systems is also provided.

The invention is directed to compositions and methods for preparing electrospun matrices comprising at least one natural biological material component and at least one synthetic polymer material. The natural component makes the matrices highly biocompatible while the molecular weight polymer component can impart additional strength mechanical strength to the scaffold and/or improve ease of manufacture by increasing viscosity and spinning characteristics of the solution during electrospining.

Thermoplastic polyurethanes having an alternating sequence of hard and soft segments in which a nanostructured polyhedral oligosilsesquioxane diol is used as a chain extender to form a crystalline hard segment constituting SMPs. The polyurethanes are formed by reacting a polyol, a chain extender dihydroxyl-terminated polyhedral oligosilsesquioxane and a diisocyanate. The polyurethanes have multiple applications including for example, implants for human health care, drug delivery matrices, superabsorbant hydrogels, coatings, adhesives, temperature and moisture sensors, etc.

A vinyl-group-containing dendrimer useful in coating and printing and is curable by any one of conventional triggers such as heating, ultraviolet light, infrared light, electron beams and gamma rays, the composition comprising a vinyl-group-containing dendrimer (A) comprising a core portion, branching portions, branches and at least 4 terminal portions and having a vinyl group as a terminal portion and a long-chain group and a curable unsaturated-group-containing compound (B), and the composition comprising a vinyl-group-containing dendrimer (A) obtained by reacting a polyfunctional compound (a) having at least three active-hydrogen-containing groups in a terminal per molecule and having at least five active hydrogen atoms per molecule with a long-chain-group-containing compound (b) having a functional group reactive with an active hydrogen atom so as to leave part of the active hydrogen atoms, thereby obtaining a long-chain-group-containing multi-branched compound (X), and reacting the long-chain-containing multi-branched compound (X) with a vinyl-group-containing compound (c) having a functional group reactive with an active hydrogen atom and a curable unsaturated-group-containing compound (B).

Disposable absorbent articles comprising an absorbent material and a degradable thermoplastic polymer composition comprising an aliphatic polyester and an antimicrobial composition. The antimicrobial composition includes an antimicrobial component and an enhancer component. The aliphatic polyester and antimicrobial composition are formed into webs by melt extrusion, such as nonwovens and films, that are incorporated into disposable absorbent articles, such as disposable infant diapers, adult incontinence articles, feminine hygiene articles such as sanitary napkins, panty liners and tampons, personal care wipes and household wipes to provide odor control, control of microbial growth, and control of microbial toxin production.

The present invention relates to a process and system for gasifying biomass or other carbonaceous feedstocks in an indirectly heated gasifier and provides a method for the elimination of condensable organic materials (tars) from the resulting product gas with an integrated tar removal step. More specifically, this tar removal step utilizes the circulating heat carrier to crack the organics and produce additional product gas. As a benefit of the above process, and because the heat carrier circulates through alternating steam and oxidizing zones in the process, deactivation of the cracking reactions is eliminated.

A composition comprising a polymer comprising a repeat unit of Formula I.: wherein R<1 >is independently in each occurrence H, C1-40 hydrocarbyl or C3-40 hydrocarbyl containing one or more S, N, O, P or Si atoms, or both of R<1 >together with the 9-carbon on the fluorene, may form a C5-20 ring structure which may contain one or more S, N, or O atoms; R2 is independently in each occurrence C1-20 hydrocarbyl, C1-20 hydrocarbyloxy, C1-20 thioether, C1-20 hydrocarbyloxycarbonyl, C1-20 hydrocarbylcarbonyloxy, or cyano; a is independently in each occurrence, 0 or 1; X is O, S, SO2, C(R<3>)2 or N-R<3 >wherein R<3 >is aryl or substituted aryl of C6 to C40, aralkyl of C6 to C24, or alkyl of C1 to C24. Preferably R<3 >is aryl of C6 to C24 and more preferably R<3 >is an alkylated aryl group of C6 to C24; Ar is an aryl or heteroaryl group of C6 to C40 or substituted aryl or heteroaryl group of C6 to C40, preferably C6-C24, and most preferably C6-C14. Y is a conjugated moiety that can vary in each occurrence of the repeat unit.

A process for condensing polyamides to increase their molecular weight, using a compound having at least two carbonate units comprises using a polyamide which, as a result of its preparation, comprises from 5 to 500 ppm of phosphorus in the form of an acidic compound, and adding, to the polyamide, from 0.001 to 10% by weight of a salt of a weak acid, thus eliminating the inhibiting action of the phosphorus compound.

The invention relates to a loaded non-metallocene catalyst and a preparation method and application thereof. The loaded non-metallocene catalyst has the characteristics of simple and practicable preparation method, flexible and adjustable polymerization activity and the like. The invention also relates to the application of the loaded non-metallocene catalyst to the homopolymerisation/copolymerization of olefin. Compared with the prior art, the application has the characteristic of small using amount of a cocatalyst.

An ink composition containing at least a polymerizable composition, a pigment, and a polymer represented by General Formula (1):

where R¹ represents an (m+n)-valent organic linking group, R² represents a single bond or divalent organic linking group; A¹ represents a monovalent organic group having a pigment adsorption structure that contains at least one selected from organic pigment structure, heterocyclic structure, acidic group, group having a basic nitrogen atom, urea group, urethane group, group having a coordinating oxygen atom, hydrocarbon group having 4 or more carbon atoms, alkoxysilyl group, epoxy group, isocyanate group, and hydroxyl group; the n groups A¹ and bonds or groups R² may independently be the same or different; “m” is 1 to 8, “n” is 2 to 9, and m+n is 3 to 10; P¹ represents a polymer skeleton; and the m skeletons P¹ may be the same or different.

High radiopacity is achieved in a polymeric marker by combining a polymeric resin, a powdered radiopaque agent having uniformly shaped particles of a specific particle size distribution, and a wetting agent. The method to produce the marker calls for the blending and pelletization of these materials followed by extrusion onto support beading. The resulting supported tubing is subsequently cut to length with the beading still in place. After ejection of the beading remnant the marker is slipped into place on the device to be marked and attached by melt bonding. Marking of a guide wire allows lesions to be measured while the marking of balloon catheters allow the balloon to be properly positioned relative to a lesion.

The invention discloses a temperature resistant salt tolerant high efficiency gel and a preparation method and application thereof. The preparation method is characterized in that the preparation method comprises the following steps: preparing a comb-shaped associated copolymer PAH containing macromonomers and functional hydrophobic monomers into an aqueous solution having the concentration of 0.1 to 4g/L, the crosslinking agent concentration of 0.01 to 1.0g/L, the surfactant concentration of 0.01 to 8mmol/L and the sodium sulfite thermal stabilizer concentration of 0.005 to 1.0g/L; adding the aqueous solution into a mixing container with a stirring device; stirring the aqueous solution evenly at the room temperature; regulating the pH value of the solution to be equal to between 4 and 11, and obtaining a temperature resistant salt tolerant high efficiency gel polymer solution system used for tertiary oil recovery and scavenge, displacement modification, profile modification or water shutoff. The polymer solution system has micro-crosslinking to form the gel during the flowage inside the oil reservoir. The gel has good elasticity, not easy dehydration, stable gelling performance, and excellent tackification, temperature resistance, salt tolerance, shearing resistance and ageing resistance.

This invention enables forming a photo-alignment film having a large LC anchoring strength in an IPS type liquid crystal display device. An alignment film is adapted to have a two-layer structure including a photo-alignment film and an alignment film with enhanced film strength. The photo-alignment film is formed of a precursor of polyamide acid ester, 80 percent or more of which is polyamide acid ester including cyclobutane. The alignment film with enhanced film strength is formed of a precursor of polyamide acid. After irradiating the substrate with ultraviolet light for photo-alignment, the substrate is heated. Thus, it is possible to achieve a high LC anchoring strength of the alignment film as the whole for photo-alignment, without degrading the mechanical strength of the alignment film with enhanced film strength.