21 results about "Salicylic acid ester" patented technology

A kind of recyclable high molecular weight polysalicylate green material belongs to the field of material synthesis. With six-membered ring internal anhydride ester monomer (R-SAOCAs) prepared from salicylic acid and its derivatives as raw material, Lewis base and thiourea (urea) are used to catalyze the fast controllable ring-opening polymerization of the monomer at room temperature in inert gas atmosphere and in suitable polymerization solvent, to prepare polysalicylate polymer material with number average molecular weight of more than 100,000 and molecular weight distribution within 1.30, and with accurate structure. The new type of polysalicylate polymer material has a high glass transition temperature comparable to polystyrene, and can be used as a substitute product of petroleum-based chemicals. At the same time, the polyester structure of the main chain endows the material with good degradation performance, and the material can be recycled and regenerated into salicylic acid small molecules under suitable conditions. The development of the new type of high molecular weight polysalicylate material provides a new window for the sustainable development of green materials.

The present invention provides a blood-sucking insect repellent composition that not only repels blood-sucking insects but also provides sustained deodorization of unpleasant odors that adhere to clothing. [Solution] A blood-sucking insect repellent composition containing an insect repellent component and a fragrance component, wherein the insect repellent component is at least one selected from the group consisting of ethyl 3-(N-butylacetamide)propionate, picaridin, p-menthane-3,8-diol, and N,N-diethyltoluamide, and the fragrance component is a compound that does not have electron-conjugated parts other than electron-conjugated parts derived from a benzene ring, a benzoic acid ester structure, or a salicylic acid ester structure, has 6 to 18 carbon atoms, a molecular weight of 98 to 270, has carbon atoms, hydrogen atoms, and oxygen atoms, and does not have sulfur atoms, nitrogen atoms, or halogen atoms.

The application provides a composite catalyst and a preparation method thereof, and a preparation method of a salicylate compound. The preparation method of the composite catalyst comprises the following steps: mixing a carbon carrier with a hydrotalcite for mixing treatment to prepare a mixture; and performing calcination treatment on the mixture to prepare the composite catalyst. When the composite catalyst prepared by the preparation method is used in an ester exchange reaction, the catalyst has high catalytic activity and is not prone to reaction with water, and can be repeatedly used.

The invention relates to a modified titanate catalyst, a single-component RTV (Room Temperature Vulcanization) dealcoholization condensation type silicone sealant and a preparation method of the single-component RTV dealcoholization condensation type silicone sealant. The salicylate is used for modifying titanium isopropoxide to obtain modified titanate, the modified titanate has high catalytic activity and excellent storage stability, and the single-component RTV dealcoholization condensation type silicone sealant prepared by taking the modified titanate as a catalyst has the advantages that the single-component RTV dealcoholization condensation type silicone sealant can be used for preparing the single-component RTV dealcoholization condensation type silicone sealant, and the service life of the single-component RTV dealcoholization condensation type silicone sealant is prolonged. The contradictory relationship between the curing rate and the storage performance of the sealant can be obviously improved. The single-component RTV dealcoholized condensed silicone sealant disclosed by the invention can simultaneously have relatively high curing rate and excellent storage stability, and still has very high reaction activity after being stored for a long time; and the adhesive has the advantages of good adhesive property, wide application range of base materials and good adhesive property with various base materials.

The present application discloses hyaluronic acid derivatives, specifically hyaluronic acid esters synthesized from hyaluronic acid or its salt and salicylic acid esters. The hyaluronic acid esters disclosed in the present application are characterized by good water solubility, low irritation, and mild properties, optimizing the stratum corneum. Furthermore, the water-soluble esters inhibit the penetration of salicylic acid into the stratum corneum and extend the duration of salicylic acid's action in the stratum corneum. The unique chemical structure of the salicylic acid hyaluronic acid esters of the present application immobilizes acidic functional groups, reducing the irritation of salicylic acid. The increased hyaluronic acid polysaccharide content effectively delays the penetration of salicylic acid into the deeper layers of the skin, prolonging its action time in the epidermis, targeting the stratum corneum and contributing to the long-term regulation of keratinocytes. The improved solubility of salicylic acid itself in the aqueous phase facilitates its use in formulations.

The present invention provides a process for the preparation of salicylate compounds. Especially, the preparation of salicylate compounds comprises a carboxylation reaction of reacting the phenols to obtain the corresponding salicylate compounds under the carbon monoxide, and in presence of base in a suitable solvent. According to the present invention, the carboxylation reaction can be carried out under 2 MPa and 180 ℃. The process according to the present invention allows for the preparation of salicylate compounds such as 4, 4'-dihydroxy- [1, 1'-biphenyl] -3, 3'-dicarboxylic acid in a greener, safer and highly efficient manner, which is suitable for large-scale production.

A method for synthesizing an aluminium-fluoride complex obtainable by reacting together: a salt made of aluminium(III) and counterions of aluminium(III) other than chloride(I), and a fluoride anion; or a chelate bearing molecule precomplexed with aluminium(III), obtained from treating the chelate bearing molecule with a salt made of aluminium(III) and counterions of aluminium(III) other than chloride(I), and a fluoride anion; the fluoride being [19F]fluoride or radioactive [18F]fluoride; wherein the counterions of aluminium(III) other than chloride are selected from bromide, iodide, nitrate, phosphate, sulfate, sulphonate, hydroxide, any anionic salt of natural and non-natural amino acids, 2,4-pentanedionate, 8-hydroxyquinoline, acetate, acrylate, ascorbate, aspartate, benzenesulfonate, benzoate, besylate, bitartrate, camphorsulfonate, citrate, decanoate, esylate, fumarate, gentisate, gluconate, glutamate, glutarate, glycinate dihydroxide, glycolate, hexanoate, hydroxynaphthoate, isethionate, lactate, lactobionate, malate, maleate, malonate, mandelate, mesylate, methylsulfate, methylsulfonate, mucate, napsylate, octanoate, oleate, oxalate, pamoate, pantothenate, phthalate, polygalacturonate, propionate, salicylate, stearate, succinate, tartrate, teoclate, toluenesulfonate, trifluoroacetate, trifluoromethanesulfonate, and any combination thereof.

This disclosure provides a method for alleviating the damaging effects of D. maidis in corn crops, which involves the use of plant defense elicitors such as jasmonates and salicylates.

The invention belongs to the technical field of gaultheria yunnanensis extraction, and provides a method for separating and purifying effective components of gaultheria yunnanensis. The method for separating and purifying the effective components of the gaultheria yunnanensis comprises the following steps: mixing gaultheria yunnanensis powder and a solvent, and carrying out ultrasonic extraction to obtain an extracting solution; extracting the extracting solution by adopting a mixed solvent to obtain an extraction phase and a raffinate phase; and removing the solvent from the raffinate phase to obtain the lignan effective component. And removing the solvent from the extract phase to obtain the salicylate effective component. According to the method disclosed by the invention, the gaultheria yunnanensis powder is extracted by using the mixed solvent of the ethyl acetate and the methanol, so that lignan active ingredients and salicylate active ingredients in the gaultheria yunnanensis can be extracted at the same time, and efficient co-extraction of multiple ingredients is realized; a mixed solvent of n-butyl alcohol and dichloromethane is adopted to extract an extracting solution, and lignan effective components and salicylate effective components can be efficiently separated at the same time only through one-time extraction.

The purpose of the present disclosure is to provide a sanitary article capable of repelling not only mosquitoes but also mites by mosquito and mite repelling components. This sanitary article has the following feature.　This sanitary article (1) comprises a mosquito and mite repellent (13) containing mosquito and mite repelling components that include at least one among acetate and salicylate.

The application relates to the technical field of anticorrosive coatings, and discloses an environment-friendly fluorine-free aluminum alloy surface anticorrosive coating and a preparation method thereof, which comprises the following steps: based on ion exchange, single-quaternary ammonium salt seven (salicylate group) cage polysilsesquioxane is used to perform intercalation modification treatment on sodium-based montmorillonite to obtain a stable interlayer spacing type montmorillonite loaded with salicylate groups and polysilsesquioxane groups; based on the pi-pi stacking effect between phenyl groups, the stable interlayer spacing type montmorillonite is compounded with a bisphenol A glycidyl ether type epoxy resin, and is subjected to emulsification treatment through phase inversion to obtain a corrosion-resistant and weather-resistant water-based epoxy resin emulsion; and the environment-friendly fluorine-free aluminum alloy surface anticorrosive coating is prepared by taking the corrosion-resistant and weather-resistant water-based epoxy resin emulsion as a film-forming raw material. The coating product not only has excellent corrosion resistance, but also has high weather resistance, and can resist corrosion media and environmental aging at the same time when used on the surface of an aluminum alloy.

This invention relates to the fields of cosmetics and pharmaceutical chemistry, and discloses a glycyrrhizin salicylate ester and its applications. The structural formula of the glycyrrhizin salicylate ester is shown in Formula I. The glycyrrhizin salicylate ester of this application uses glycyrrhizin and salicylic acid as starting materials, and combines the two active molecules into one through dehydration ester condensation, fundamentally solving the problem of easy oxidation and inactivation of glycyrrhizin, and significantly improving chemical stability. At the same time, this structure cleverly masks the strongly acidic carboxyl group of salicylic acid, resulting in a significant reduction in skin irritation of the final product, making it far milder than physical mixtures, with better tolerance and suitability for a wider range of skin types. The glycyrrhizin salicylate ester of this application combines the excellent whitening and antioxidant effects of glycyrrhizin with the excellent keratin-regulating and anti-inflammatory capabilities of salicylic acid, and has broad application prospects in the preparation of topical products for skin whitening, spot fading, anti-inflammation, anti-acne, and anti-photoaging.

The invention discloses a composition for improving sunscreen performance, a product and a preparation method thereof, and the composition comprises the following components in parts by mass: 5-32 parts of difatty acyl pentaerythritol difatty alcohol citrate, 5-32 parts of tribehenin and 61.5-90.9 parts of salicylate derivative. According to the invention, the salicylate sunscreen agent with low greasy feeling is compounded with the di-fatty acyl pentaerythritol di-fatty alcohol citrate and the tribehenin, so that the salicylate sunscreen cosmetics with low sunscreen efficiency originally have excellent sunscreen efficiency while maintaining excellent skin feeling.

The invention relates to the technical field of cosmetics, in particular to an oil-controlling and acne-removing composition and application thereof. The oil control and acne removal composition disclosed by the invention is prepared from the following components in parts by weight: 0.11 to 0.18 part of hectorite, 0.35 to 0.40 part of silica, 1.2 to 2.0 parts of silanediol salicylate and 0.2 to 0.4 part of rhamnolipid. The oil-controlling and acne-removing composition is used for preparing silica-containing suspension type toning lotion, not only effectively solves the problems of sinking to the bottom, caking, uneven dispersion and the like caused by independently adding silica into the toning lotion, but also remarkably improves the rheological property and the stability of the product. The oil-controlling and acne-removing composition provided by the invention acts from three dimensions of oil controlling, bacteriostasis and repairing, has multifunctionality and stability, and can provide safer and more efficient skin care experience.

The present invention relates to a cosmetic or pharmaceutical composition comprising at least one cosmetically or pharmaceutically acceptable excipient and a photoprotective system consisting of: (a) 5,6,5′,6′-tetraphenyl-3,3′-(1,4-phenylene)-bis[1,2,4]triazine, (b) 2,4-bis[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, (c) hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate, and (d) a solar filter selected from the group comprised of ethylhexyl triazone, diethylhexyl butamido triazone and 2-ethylhexyl salicylate, wherein the photoprotective system represents between 4% and 20% by weight of the composition relative to the total weight of the composition.

The application provides a method for synthesizing salicylate by cyclization and dehydrogenation, specifically, C3 aldehyde and acetoacetic ester are subjected to gas phase cyclization reaction under the catalysis of a solid base to obtain 2-oxo-3-cyclohexene acid ester intermediate, and the intermediate is then subjected to dehydrogenation aromatization under the action of a dehydrogenation catalyst and an assistant to obtain salicylate product. The application uses cheap and readily available C3 aldehyde and acetoacetic ester as starting materials, quickly synthesizes salicylate through two steps, has a short synthesis route, high yield, less waste and good cost advantage; in the gas phase condensation cyclization reaction, lithium phosphate and potassium salt solid mixture are used as the catalyst to efficiently catalyze the condensation reaction of C3 aldehyde and acetoacetic ester, and 2-oxo-3-cyclohexene acid ester intermediate is obtained; in the dehydrogenation reaction, the dehydrogenation catalyst and nitrite assistant are used in combination, the nitrite promotes the isomerization between the ketonic form and the enolic form of 2-oxo-3-cyclohexene acid ester, reduces the temperature required for the dehydrogenation reaction, and promotes the dehydrogenation reaction.

The present application is related to a pharmaceutical composition a biphasic lipid vesicle comprising a lipid bilayer comprising vesicle forming lipids; an oil-in-water emulsion stabilized by one or more surfactants; one or more compounds; and one or more penetration enhancing agents. The one or more penetration enhancing agents include one or more non-ionic surfactants having a hydrophilic-lipophilic balance (HLB) of about 10 or less, alone or combination with one or more penetration enhancing agents selected from one or more of terpenes, alkaloids, salicylate derivatives, and polycationic surfactants and combinations thereof. The present application is also related to a pharmaceutical composition comprising a biphasic lipid vesicle comprising a lipid bilayer comprising vesicle forming lipids; an oil-in-water emulsion stabilized by one or more polycationic surfactants; and one or more compounds.

The present application relates to the technical fields of medical and pharmaceutical chemical synthesis, in particular to a synthesis method of 3-trifluoromethyl-1,4-benzoxazepine compound, the steps are as follows: in the reactor, compound 1, compound 2, additive are added, stirred for 4 hours under the condition of 100 DEG C air, after the reaction is finished, cooling to 0 DEG C, adding base and reacting overnight.Extraction, vacuum distillation to obtain the crude product, and then column chromatography and thin layer chromatography chromatography purification to obtain 3-trifluoromethyl-1,4-benzoxazepine compound.The present application uses trifluoromethyl imine ylide compound and salicylate compound as raw materials, and synthesizes 3-trifluoromethyl-1,4-benzoxazepine compound by one-pot method.The present application has the advantages of simple synthesis steps, easy-to-obtain raw materials, no need to separate intermediate, no need to use precious metal catalyst, good functional group compatibility, etc.;and high reaction conversion, low cost, which is conducive to industrial production.

The invention relates to the technical field of medicines, and provides a preparation method of sodium 8-(2-hydroxybenzamido) octanoate, aiming at the problems of complicated synthesis steps and low product purity of the sodium 8-(2-hydroxybenzamido) octanoate. The reaction route is as follows: the compound II is 8-amino caprylic acid salt, and X in the formula is HCl, 1 / 2 H2SO4 or 1 / 3 H3PO4; the compound III is salicylate, and in the formula, R is methyl or ethyl; the compound I is 8-(2-hydroxybenzamido) sodium caprylate. The method is a one-step synthesis method, the route is short, the used raw materials are cheap and easy to obtain, the cost is low, and the method has important industrial application value.

The present invention relates to a polycarbonate obtained by melt-reacting bisphenol A and a carbonate, optionally in the presence of a transesterification catalyst, where the polycarbonate comprises a salicylate Fries unit represented by formula (I), a linear Fries unit represented by formula (II), and a branched Fries unit represented by formula (III), where the salicylate Fries unit is represented by formula (I), the linear Fries unit is represented by formula (II), and the branched Fries unit is represented by formula (III). Wherein the amount of salicylate Fries units in the polycarbonate is at least 10% by weight, relative to the total amount of salicylate Fries units, linear Fries units and branched Fries units in the polycarbonate, and / or the amount of salicylate Fries units in the polycarbonate is at least 50 ppm.

The invention discloses a mildew-proof silicone adhesive and a preparation method thereof, belongs to the technical field of polymer sealing materials, and aims to solve the problems of short mildew-proof life and environmental pollution of the existing mildew-proof sealant. The mildew-proof silicone adhesive is prepared from the following raw materials in parts by weight: 100 parts of basic adhesive, 10 to 25 parts of plasticizer, 5 to 12 parts of reinforcing filler, 40 to 80 parts of filling filler, 4 to 8 parts of cross-linking agent, 1 to 3 parts of biological avoidance modifier, 0.5 to 2.0 parts of phase separation inducer A, 0.75 to 3.0 parts of phase separation inducer B and 0.05 to 0.2 part of catalyst, the phase separation inducer A is perfluoropolyether modified silane; the phase separation inducer B is long-chain alkyl silane; the biological avoidance modifier is salicylate modified silane; the reinforcing filler is fumed silica; the filling filler is nano calcium carbonate. The waterproof mildew-proof paint does not contain heavy metals and toxic mildew-proof components, has excellent hydrophobic self-cleaning property and long-acting mildew-proof property, and is particularly suitable for joint sealing in high-humidity environments such as kitchens and toilets in building decoration.