The invention concerns arrays of
solid-forms of substances, such as compounds and rapid-screening methods therefor to identify
solid-forms, particularly of pharmaceuticals, with enhanced properties. Such properties include improved
bioavailability,
solubility, stability, delivery, and
processing and manufacturing characteristics. The invention relates to a practical and cost-
effective method to rapidly screen hundreds to thousands of samples in parallel. The invention further provides methods for determining the conditions and / or ranges of conditions required to produce crystals with desired compositions, particle sizes, habits, or polymorphic forms. In a further aspect, the invention provides high-
throughput methods to identify sets of conditions and / or combinations of components compatible with particular
solid-forms, for example, conditions and / or components that are compatible with advantageous polymorphs of a particular pharmaceutical.