25 results about "Avobenzone" patented technology

The application provides a candidate drug for promoting embryo implantation efficiency of patients with uterine redox imbalance type RIF, and belongs to the technical field of embryo implantation. In order to solve the problem of how to find potential intervention drugs for the pathological mechanism of uterine redox imbalance type RIF, a five-step high-efficiency drug screening strategy based on an in-vitro implantation model of uterine redox imbalance type repeated embryo implantation failure is adopted to ensure the reliability and functional correlation of the screening results. The candidate drug screened by the five-step high-efficiency drug screening strategy includes any one of the following drugs: avobenzone, vasopressin, ethylenediaminetetraacetic acid dipotassium, larotrectinib sulfate, citicoline, opicapone, iclapa, L-leucine, fulvestrant, malic acid and lucotinib. Among these candidate drugs, avobenzone, vasopressin and ethylenediaminetetraacetic acid dipotassium are the best three drugs for promoting the implantation efficiency of patients with uterine redox imbalance type RIF.

The invention provides a candidate medicine for promoting the embryo implantation efficiency of a uterus redox imbalance type RIF patient, and belongs to the technical field of embryo implantation. In order to solve the problem of how to discover a potential intervention drug aiming at a uterine redox imbalance type RIF pathological mechanism, a five-step efficient drug screening strategy based on an in-vitro implantation model of uterine redox imbalance type repeated embryo implantation failure is adopted, so that the reliability and functional correlation of a screening result are ensured. A candidate drug screened by adopting a five-step method efficient drug screening strategy comprises any one of the following drugs: avobenzone, vasopressin, dipotassium ethylene diamine tetraacetate, lalotinib sulfate, citicoline, olprinone, eltrombopag, L-leucine, fulvestrant, malic acid and rucotinib. Among the candidate drugs, avobenzone, vasopressin and dipotassium ethylenediaminetetraacetate are three drugs with optimal implantation promotion efficiency for patients with uterine redox imbalance type RIF.

The invention relates to a preparation method of avobenzone, which comprises the steps of preparation of an intermediate 1, preparation of an avobenzone crude product, refining of avobenzone and the like, the molar yield of avobenzone prepared by the method is more than 92%, and the content of avobenzone reaches 98.5-99.8%.

The invention relates to the technical field of daily cosmetics, in particular to an avobenzone sunscreen composition based on synergistic stabilization of large-particle-size cerium oxide and a light protective agent and application of the avobenzone sunscreen composition. The sunscreen composition comprises the following components in percentage by weight: 2-4% of avobenzone; 0.5 to 1.5 percent of cerium oxide with the particle size range of 950 to 5000nm And 3-5% of a light protective agent. The problems of photo-thermal stability and low irritation of avobenzone are solved through the synergistic effect of the large-particle-size cerium oxide and the light protective agent.

The present invention provides a sunscreen composition comprising: (i) avobenzone; (ii) homosalate; (iii) octocrylene; (iv) octisalate; (v) hydrogenated castor oil; and (vi) carnauba wax; wherein the composition is a liquid, oil-in-water emulsion and provides an SPF of at least 70.

A cosmetic sunscreen composition comprises avobenzone and one or both of Rosmarinus Officinalis (Rosmary) Leaf Extract and Haematococcus Pluvialis Extract to stabilize the avobenzone.

COMPOSITIONS CONTAINING BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE AND AVOBENZONE This disclosure relates to compositions including 2,4-bis-{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine, avobenzone, and optionally octinoxate, as well as processes for manufacturing and using such compositions. Figure for abstract: none

A cosmetic sunscreen composition comprises avobenzone and one or more of Raspberry Ketone, γ-Oryzanol and Ethyl Ferulate to stabilize the avobenzone.

The invention relates to an anti-ultraviolet aging quantum dot lens and a preparation method thereof, and the anti-ultraviolet aging quantum dot lens comprises the following components in percentage by mass: 0.01-10% of a quantum dot composite dispersion, 2-8% of an anti-ultraviolet composite additive, 0.5-5% of an auxiliary functional additive and the balance of acrylic, raw materials of the anti-ultraviolet composite additive comprise a lignin composite capsule, and the lignin composite capsule comprises lignin and avobenzone. The quantum dot lens has the effect of improving the anti-ultraviolet performance of the quantum dot lens.

A fusing agent for three-dimensional printing can include from about 5 wt % to about 40 wt % water; from about 4 wt % to about 60 wt % C7 to C12 aliphatic ester cosolvent; and from about 0.5 wt % to about 10 wt % solubilized avobenzone.

The invention provides a composite catalyst, a preparation method thereof and a preparation method of avobenzone. The composite catalyst comprises a metal salt, an organic ligand and a carrier. According to the invention, p-methoxyacetophenone and methyl p-tert-butylbenzoate are used as raw materials, the composite catalyst is used as a catalyst, and reaction is carried out in a solvent to obtain avobenzone. The composite catalyst provided by the invention is used for catalytically preparing avobenzone, reaction can be carried out under relatively mild reaction conditions, the product yield is high, no corrosion is caused to equipment, no waste water or waste salt is generated, and the method is green and environment-friendly.

The invention belongs to the technical field of fine chemical engineering, and discloses avobenzone as well as a preparation method and application thereof. The preparation method of avobenzone comprises the following steps: mixing 4-methoxybenzaldehyde, 4-tert-butyl acetophenone and a mixed solvent, and carrying out a first reaction to obtain a diaryl beta-diketone intermediate; carrying out a second reaction on the diaryl beta-diketone intermediate and a methoxy phenyl halide to obtain avobenzone; wherein the mixed solvent comprises an organic solvent, lewis acid and organic alkali. The preparation method is mild in condition, short in reaction time, few in side reaction and high in yield, and the purity of the prepared avobenzone is high.

A cosmetic sunscreen composition comprises avobenzone and one or both of Rosmarinus officinalis (Rosmary) Leaf Extract and Haematococcus pluvialis Extract to stabilize the avobenzone.

The present invention relates generally to methods and compositions useful for sunscreen compositions comprising avobenzone and a solvent capable of solubilizing avobenzone.

The present invention relates generally to methods and compositions useful for sunscreen compositions comprising avobenzone and a solvent capable of solubilizing avobenzone.

Topical anhydrous sunscreen compositions that comprise glycereth-26 and avobenzone and / or glycerteh-26. In addition to boosting SPF and UVA-PF values, glycereth-26 provides excellent aesthetics, sensory profiles and spreading ability, and is particularly suitable for use in anhydrous systems. Compositions of the invention may be in the form of oil / oil, oil / silicone, or silicone / oil emulsions, as well as multi-phase anhydrous systems, such as oil / silicone / oil.

Disclosed is a sunscreen composition comprising avobenzone, octocrylene, octyl salicylate, and aluminum starch octenylsuccinate. Also disclosed is a method for protecting skin from ultraviolet radiation, the method comprising topically applying to the skin a composition comprising an effective amount of avobenzone, octocrylene, octyl salicylate, and aluminum starch octenylsuccinate.

The application discloses application of avobenzone in preparation of a preparation for reducing ATG14 protein content in cells; specifically, the avobenzone can directly combine with the ATG14 protein, and promote the ATG14 to degrade the ATG14 through a ubiquitin-proteasome pathway (such as CUL3 mediation), so as to destroy the PI3KC3-C1 complex stability, inhibit the autophagosome formation and reduce the autophagy flux. Further, the avobenzone can show a decrease in LC3-II lipidation level, a blocked p62 degradation and a damaged Beclin1-VPS34 complex assembly. The application discloses, for the first time, a new application of the avobenzone as an autophagy inhibitor targeting the ATG14, and provides a new technical scheme for ATG14-related autophagy mechanism research and drug screening.

The invention discloses supramolecular avobenzone as well as a preparation method and application thereof, and belongs to the technical field of supramolecules. The supramolecular avobenzone comprises two main bodies, namely an avobenzone substance and a ligand, and every two main bodies are connected through an intermolecular acting force; wherein the ligand is at least one of ferulic acid, ergothioneine, nicotinamide and tranexamic acid. The supramolecular avobenzone has good biocompatibility and mildness, the sunscreen effect and stability of the avobenzone are improved, and the supramolecular avobenzone completely retains the molecular skeleton of supramolecules, so that the biological activity and efficacy of the supramolecular avobenzone are both improved.

The present application relates to isocyanate compounds, and particularly relates to a cyclodextrin composition used as a storage stabilizer for isocyanate compounds, which comprises cyclodextrin and avobenzone. The cyclodextrin composition of an embodiment of the present application, used as a storage stabilizer for isocyanate compounds, can keep isocyanate compounds from yellowing after long-time storage, and improves the storage stability of isocyanate compounds.

Topical anhydrous sunscreen compositions that comprise glycereth-26 and avobenzone and / or glycereth-26. In addition to boosting SPF and UVA-PF values, glycereth-26 provides excellent aesthetics, sensory profiles and spreading ability, and is particularly suitable for use in anhydrous systems. Compositions of the invention may be in the form of oil / oil, oil / silicone, or silicone / oil emulsions, as well as multi-phase anhydrous systems, such as oil / silicone / oil.

The present invention provides a sunscreen composition comprising: (i) an organic UV filter selected from the group consisting of avobenzone, homosalate, octocrylene, octisalate, bis-ethylhexyloxyphenol methoxyphenyl triazine, and combinations thereof; (ii) a polymeric emulsifier selected from the group consisting of sodium acryloyldimethyltaurate / VP crosspolymer, acrylates / C10-30 alkyl acrylate crosspolymer, and combinations thereof; (iii) a solid absorbent selected from the group consisting of silica, aluminum starch octenylsuccinate, and combinations thereof; and (iv) trilaureth-4 phosphate.

COMPOSITIONS CONTAINING BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE, AVOBENZONE, AND AN ADDITIONAL UV FILTER This disclosure relates to compositions including 2,4-bis-{[4-(2-ethylhexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3,5-triazine, avobenzone, and additional organic UV filter(s), as well as processes for manufacturing and using such compositions. Figure for abstract: none

The present invention provides a sunscreen composition comprising: (i) avobenzone; (ii) homosalate; (iii) octocrylene;(iv) octisalate;(v) hydrogenated castor oil; and (vi) carnauba wax; wherein the composition is a liquid, oil-in-water emulsion and provides an SPF of at least 70.

A cosmetic sunscreen composition comprises avobenzone and one or more of Raspberry Ketone, γ-Oryzanol and Ethyl Ferulate to stabilize the avobenzone.