38 results about "Rosmarinus" patented technology

The present disclosure discloses a composition for hair growth comprising Larix europea wood extract, Camellia sinesis leaf extract, Pisum sativum sprout extract, Curcuma longa (Turmeric) callus conditioned media, Hamamelis virginiana (Witch Hazel), Rosmarinus officinalis Leaf Oil, Glycerin, Glycine, Zinc Chloride, Sodium Metabisulfite, Gluconolactone, Sodium Benzoate, Calcium Gluconate, Tetrasodium ethylenediaminetetraacetic acid (EDTA), Saccharide Isomerate, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Propanediol, Biotinoyl Tripeptide- 1, Alpha Glucosyl Hesperidin, Caffeine, Hydrolyzed Pea Protein, Polyalkylene Glycol Mono Butyl Ether, Acrylates / C 10-30 Alkyl Acrylate Crosspolymer, Panthenol, Niacinamide, Arginine, PEG-40 Hydrogenated Castor Oil, Ethylhexylglycerin, Phenoxyethanol, and water is added to the composition until the desired volume is achieved. A method for preparing the composition for hair growth is also provided.

The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for improving systemic lupus erythematosus and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 15-30 parts of dry rehmannia, 12-26 parts of calcined turtle shell, 13-25 parts of chicken tendon ginseng, 11-18 parts of red peony root, 10-20 parts of white flower snake tongue grass, 6-18 parts of small rosmarinus officinalis, 4-15 parts of artemisia annua, 5-10 parts of centella asiatica, 4-12 parts of cimicifuga foetida, 3-10 parts of coix seed, 2-9 parts of bergamot slice, and 3-7 parts of raw licorice. Test results show that the traditional Chinese medicine composition for improving systemic lupus erythematosus prepared by the application can inhibit the expression of IL-10 and IL-17 in serum, reduce anti-dsDNA antibodies in serum, significantly improve the clinical symptoms of systemic lupus erythematosus, and has a wide application prospect.

This invention relates to a whitening extract from geranium, its preparation method, and its application, belonging to the field of plant extract preparation and cosmetic technology. The extraction method includes: preparing a eutectic solvent by mixing choline chloride and citric acid in a molar ratio of 2:1 to 4:1, and adjusting the water content to 30-70%; mixing geranium raw material powder with the eutectic solvent at a material-liquid ratio of 1:5-15 (g / mL), and performing ultrasonic-assisted extraction; concentrating the extract under reduced pressure and then freeze-drying to obtain a geranium whitening extract with a total flavonoid content of 1-4 mg / g, a total polyphenol content of 3-6 mg / g, and anthocyanin content of 1-3 mg / g. This extract can be used to prepare cosmetics or topical skin preparations with whitening, brightening, antioxidant, or pigmentation-improving effects, as well as a tyrosinase activity inhibitor. This invention provides a green and efficient method for extracting the whitening active ingredients from geranium.

The present invention relates generally to methods and compositions useful for treating skin, and in particular to improve the appearance of droopy, loose, sagging, and / or flaccid skin and / or to improve facial contouring. In some aspects, disclosed are methods comprising topically applying to the skin an effective amount of a topical composition comprising escin, Ascophyllum nodosum extract, caffeine, Coleus barbatus extract, Hedychium coronarium root extract, Argania spinosa oil, Rosmarinus officianalis leaf extract, and / or Morus alba fruit extract.

The invention discloses a salvia miltiorrhiza endogenous oligopeptide composition and application thereof. The composition contains salvia miltiorrhiza endogenous oligopeptides miPEP167b-5p and miPEP171b-1, wherein the concentration ratio of the salvia miltiorrhiza endogenous oligopeptides miPEP167b-5p to the miPEP171b-1 is 0.8-1.2. The oligopeptide used in the composition has high species specificity, does not promote the growth of other plants in the field, and avoids the ecological risk of a traditional broad-spectrum growth regulator. Field experiment results show that after the composition is applied to treatment, the root system yield of salvia miltiorrhiza is increased by 56% compared with that of a control group, the number of roots is increased by 435% compared with that of the control group, the rosmarinic acid content is increased by 43% compared with that of the control group, the salvianolic acid B content is increased by 81%, the tanshinone I content is increased by 214%, the tanshinone IIA content is increased by 75%, the leap-type improvement of the salvia miltiorrhiza medicinal material yield and quality is synchronously achieved, and the application prospect is wide. And reliable technical support is provided for green, efficient and high-quality development of the salvia miltiorrhiza industry.

The invention relates to a rosemary borneol dehydrogenase SrBDH mutant and application of the rosemary borneol dehydrogenase SrBDH mutant in d-borneol, and belongs to the field of biological pharmacy and enzyme engineering. In particular to a borneol dehydrogenase SrBDH mutant derived from rosemary, a coding nucleotide of the borneol dehydrogenase SrBDH mutant, a recombinant plasmid and a recombinant genetically engineered bacterium containing the recombinant borneol dehydrogenase mutant, and application of the borneol dehydrogenase SrBDH mutant as a catalyst to preparation of d-borneol by asymmetric reduction of d-camphor. The catalytic activity of the obtained mutant is remarkably improved compared with that of a wild type, the feeding amount of the highest substrate dextrocamphor can reach 100 mM, the concentration of the product dextroborneol is gradually increased along with the prolonging of time, the yield of the dextroborneol can reach 85.0% after the reaction is conducted for 24 h, and the e.e. Value can reach 98.5%. The product d-borneol is an important natural active substance, has a high added value, and has a significant industrial application value.

The present disclosure discloses a composition for anti-graying hair comprising Aloe barbadensis Leaf Extract, Camellia sinensis leaf extract, Rosmarinus officinalis Leaf Oil, Hamamelis virginiana (Witch Hazel), Neopicrorhiza scrophulariiflora root extract, Tetrasodium ethylenediaminetetraacetic acid (EDTA), Acrylates / C 10-30 Alkyl Acrylate Crosspolymer, Panthenol, Polyalkylene Glycol Mono Butyl Ether, Ethylhexylglycerin, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Propylene Glycol, Biotin, Hyaluronic Acid, Saccharide Isomerate, Alpha Glucosyl Hesperidin, Dimethyl Isosorbide, Mandarin peel paste, N-Acetyl L-Tyrosine, Pentylene Glycol, Gluconolactone, Propanediol, and water is added to the composition until a desired volume is achieved. The method for preparing the composition for anti-gray hair is also provided.

To provide a freshness retaining agent excellent in retaining the freshness of chlorophyll.SOLUTION: The freshness of a chlorophyll-containing material is retained by using a freshness retaining agent containing rosmarinic acid, its glycoside, its derivative or its pharmacologically acceptable salt as an active ingredient. Preferably, the freshness of the chlorophyll-containing material is retained by bringing a freshness retaining agent containing rosmarinic acid derived from a perilla seeds extract, its glycoside, its derivative or its pharmacologically acceptable salts as an active ingredient into contact with plants, phytoplankton, algae or their processed products.SELECTED DRAWING: Figure 1

The application discloses a rapid detection method of rosmarinic acid in perilla seed, and belongs to the technical field of chemical detection. The rosmarinic acid in perilla seed is maximally dissolved by adopting steel balls combined with specific extraction solution to grind the perilla seed. Meanwhile, the extraction rate of the rosmarinic acid is further improved by adding an acid solution. In addition, the chromatographic conditions of high performance liquid chromatography detection of the rosmarinic acid are optimized, so that the detection time is obviously shortened, and the accuracy of the detection result is high. The rapid detection method provided by the application is simple, the raw materials are cheap and easy to obtain, and is suitable for rapid extraction and detection of rosmarinic acid in a large amount of small sample of perilla seed. Therefore, the extraction and detection method of the rosmarinic acid in the perilla seed has a good application prospect.

The invention belongs to the technical field of external medicine for treating bromhidrosis, and particularly relates to external medicine for treating bromhidrosis and a preparation method thereof.The external medicine for treating bromhidrosis comprises active ingredients and auxiliary materials, the active ingredients comprise Chinese ephedra roots, the root of kudzu vine, pepper, perilla frutescens, calendula officinalis, pericarpium citri reticulatae, fortune eupatorium herb, rhizoma atractylodis, a radix sophorae flavescentis extract, a purslane herb extract, a ginger extract, zinc oxide and citric acid; the auxiliary materials comprise IPM, Tween 20, rosemary essential oil and Kathon. The preparation method comprises the following steps: firstly, extracting Chinese ephedra root, kudzuvine root, pepper, purple perilla, calendula, dried orange peel, fortune eupatorium herb and rhizoma atractylodis with water; dissolving the sophora flavescens extract, the portulaca oleracea extract, the ginger extract and the citric acid in the traditional Chinese medicine extracting solution, and stirring until the materials are completely dissolved; zinc oxide, IPM and rosemary essential oil are mixed into a Tween 20 solution for ultrasonic treatment, and finally the mixture and Kathon are added into the mixed extracting solution. The bromhidrosis removing agent has a good bromhidrosis removing effect, no toxic or side effect and stable performance. The effects of sterilization, deodorization, hidroschesis, skin moistening, perfuming and the like are achieved.

The invention belongs to the technical field of natural anti-corrosion materials, and provides a natural anti-corrosion composition containing cinnamon bark extract and a preparation method and application of the natural anti-corrosion composition. The natural preservative composition provided by the invention comprises a cinnamon bark extract and a synergistic compound, the synergistic compound comprises a mangnolia officinalis bark extract, a perilla leaf extract, a rhizoma atractylodis root extract, a folium artemisiae argyi extract, a wrinkled gianthyssop herb extract, a radix ophiopogonis root extract, a pomegranate seed extract, a pomelo extract, a thyme leaf extract, a calendula extract, a hyperforin perforatum extract, a melaleuca alternifolia leaf extract, a ginger root extract and an eucalyptus globulus leaf extract; the mass content of cinnamyl aldehyde in the cinnamon bark extract is less than or equal to 20wt%, and the antibacterial composition has the advantages of broad-spectrum bacteriostasis, high stability, difficulty in discoloration and precipitation, acid and alkali resistance, high temperature resistance, safety and small irritation. The antibacterial composition is prepared from at least one of a ginseng root extract, a rosemary leaf extract, a papaya fruit extract, a chamomile flower extract, a soybean seed extract and a wheat bran extract, and the mass content of cinnamyl aldehyde in the cinnamon bark extract is less than or equal to 20wt%.

The application discloses a traditional Chinese medicine composition for auxiliary treatment of prostatic hypertrophy and a preparation method thereof. The traditional Chinese medicine composition is prepared from Uncaria, ethanol extract of Dehaasia bibracteata, Akebia quinata, Nelumbo nucifera, Crossandra infundibuliformis, Rosmarinus officinalis, Prunus armeniaca, Cinnamomum cassia and Salvia officinalis by processing. The traditional Chinese medicine composition has the effect of treating prostatic hypertrophy. The traditional Chinese medicine composition is mainly used for prostatic hypertrophy, and the symptoms include frequent urination, urgent urination and incomplete urination. The traditional Chinese medicine composition can reduce the prostate index of a patient with prostatic hypertrophy, regulate the sex hormone level, reduce the prostate phosphatase activity, and has a remarkable effect on treating the problems of frequent urination, urgent urination and incomplete urination caused by prostatic hypertrophy. Meanwhile, the composition is prepared from traditional Chinese medicines as raw materials, is safe to use, has high bioavailability, and has no any toxic and side effects.

A cosmetic sunscreen composition comprises avobenzone and one or both of Rosmarinus Officinalis (Rosmary) Leaf Extract and Haematococcus Pluvialis Extract to stabilize the avobenzone.

This invention discloses the SmWRKY13 gene and its application in increasing the salvianolic acid content in Salvia miltiorrhiza, belonging to the field of genetic engineering technology. By constructing a recombinant expression vector containing the SmWRKY13 gene and transforming it into hairy roots of Salvia miltiorrhiza, transgenic hairy root lines overexpressing SmWRKY13 were obtained. The salvianolic acid content of these transgenic hairy root lines was detected. The results showed that overexpression of SmWRKY13 significantly increased the content of salvianolic acid components such as rosmarinic acid and salvianolic acid B in the hairy roots of Salvia miltiorrhiza, with the total salvianolic acid content reaching up to 5.72 times that of the control group. This invention provides an effective strategy for increasing the salvianolic acid content in Salvia miltiorrhiza using genetic engineering methods, which is of great significance for meeting market demand and promoting the large-scale preparation of salvianolic acid.

The utility model discloses a kind of rosmarinus officinalis essential oil processing with squeezing device, including squeezing box, the side fixed mounting of squeezing box has driving device two, the output end transmission of driving device two is connected with rotating disc, the side of rotating disc and near edge place rotationally connected with rotating rod, one end of rotating rod is rotationally connected with sliding rack, the outer surface sliding connection of sliding rack has multiple guide blocks, the side of multiple guide blocks is fixedly connected with the side of squeezing box. The utility model is by opening driving device two, makes rotating disc rotate, sliding rack reciprocating sliding in guide block, sliding rack is cooperated with rotating gear, makes rotating roller reciprocating rotation at the bottom of filter screen one, in the process of rotation, the patting rubber on rotating roller is patting to the bottom of filter screen one, rosmarinus officinalis in filter hole is pat out, prevent long time use filter screen one, and the filtering efficiency of filter screen one is lower.

A cosmetic sunscreen composition comprises avobenzone and one or both of Rosmarinus officinalis (Rosmary) Leaf Extract and Haematococcus pluvialis Extract to stabilize the avobenzone.

The invention belongs to the technical field of plant genetic engineering, and particularly relates to a construction method and application of a hairy root system of dracocephalum heterophyllum benth with high rosmarinic acid content. According to the method, dracocephalum heterophyllum benth aseptic seedling stem segments are used as explants, agrobacterium rhizogenes LBA9402 carrying a rosmarinic acid synthase (RAS) gene expression vector is used for infection, co-culture and induction, and then positive transgenic hairy roots integrated with the RAS gene are obtained through multi-stage screening and identification. The dracocephalum heterophyllum hairy root system established by the invention has the characteristics of genetic stability, rapid growth and strong rosmarinic acid synthesis capability, the rosmarinic acid content is obviously increased, and an efficient biotechnology platform is provided for realizing large-scale and sustainable production of rosmarinic acid.

The application relates to the technical field of pharmaceutical analysis, in particular to a method for determining the content of rosmarinic acid in a standard decoction of wind wheel herb and a method for constructing a characteristic spectrum. The high performance liquid chromatography method is used for determination, and the conditions of the high performance liquid chromatography method include that octadecylsilane bonded silica gel is used as a filler of a chromatographic column; methanol is used as a mobile phase A, and a 0.1% formic acid aqueous solution is used as a mobile phase B, and gradient elution is carried out. The method has strong specificity, good repeatability and durability, high stability and high accuracy; the constructed characteristic spectrum and detection method can quickly and comprehensively realize the purpose of combined control of multiple components in the standard decoction of wind wheel herb, realize quality control of the wind wheel herb from medicinal materials to preparations, and are favorable for guaranteeing the effectiveness of clinical medication.

The invention belongs to the technical field of microorganisms, and particularly relates to rhizobium hainanense A21, a growth-promoting microbial agent, a method and application. The invention provides the rhizobium hainanense A21, and the preservation number of the rhizobium hainanense A21 is CGMCC (China General Microbiological Culture Collection Center) No. 34687. The Hainan rhizobium A21 bacterial colony is in a round raised shape, smooth and wet in surface, neat in edge, semitransparent and white. The rhizobium hainanense A21 is separated from rhizosphere soil of salvia miltiorrhiza, and is used as an elicitor to culture hairy roots of salvia miltiorrhiza, so that the contents of salvianolic acid B, rosmarinic acid, salvianolic acid Y, tanshinol, alkannic acid and salvianolic acid A can be increased.

According to the method, a hyperspectral imaging technology is combined with a chemometrics method, and the content prediction of five main salvianolic acid components such as salvianolic acid B, rosmarinic acid, tanshinol, salvianolic acid Y and alkannic acid is researched. The method comprises the following steps: firstly, performing noise reduction processing on original spectral data by using a common preprocessing method, and establishing a quantitative model by using partial least square regression, a back propagation neural network and a random forest regression algorithm; and then a characteristic wave band optimization model is screened by applying four algorithms such as iteratively retaining information variables. According to the method for detecting the content of the phenolic acid components in the radix salviae miltiorrhizae based on the hyperspectral imaging technology, the content of the phenolic acid components in the radix salviae miltiorrhizae can be rapidly and accurately evaluated, and the method has important significance on quality evaluation of the radix salviae miltiorrhizae.

The invention discloses a swelling and pain relieving ointment and a preparation method thereof. The swelling and pain relieving ointment comprises the following components in percentage by weight: 15%-35% of roots and leaves of ardisia quinquefolia, 15%-25% of herb of emilia sonchifolia, 10%-20% of leaves of ovateleaf holly bark, 5%-15% of leaves of buddleia lindleyana and 25%-40% of a camellia oil matrix. The preparation method comprises the following steps: 1) taking roots and leaves of ardisia quinquefolia, whole herb of emilia sonchifolia, leaves of ovateleaf holly bark and leaves of buddleia, drying at a low temperature of 30-50 DEG C, mixing, and crushing to 150-200 meshes through a traditional Chinese medicine wall breaking technology to obtain a pretreated mixed medicinal material; 2, the pretreated mixed medicinal materials and a camellia oil matrix are mixed and stirred into paint.The swelling and pain relieving ointment has the effects of clearing away heat and toxic materials, relieving swelling and pain, promoting blood circulation to remove blood stasis, removing necrotic tissue and promoting tissue regeneration, and is mild in nature and flavor, small in skin irritation and high in transdermal absorption rate.

The utility model discloses a rosemary essential oil processing and discharging device relates to rosemary essential oil production and processing technical field, and it is including: the storage tank conveying mechanism, the storage tank conveying mechanism is used for conveying essential oil storage tank to the discharging station, the essential oil discharging mechanism, the essential oil discharging mechanism is used for the partial packing of rosemary essential oil and discharges, and the transposition receiving mechanism, the transposition receiving mechanism includes the fixed seat fixed in the top of workstation, the fixed seat top is rotated and is nested with the bearing and is provided with the rotating shaft, the rotating shaft outside evenly fixed four groups of receiving components, and any one group receiving component all includes the push board fixed in the rotating shaft outside, push board top fixedly arranged has the rack. The utility model can utilize the pushing of essential oil storage tank transmission process and realize the receiving of residual rosemary essential oil to avoid residual essential oil drop to the surface of essential oil storage tank or conveying belt, and it is more convenient when actually using.

The application discloses a preparation method of high-solubility clear and transparent rosmarinic acid. The method comprises the following steps: subjecting dry rosemary leaves to water vapor distillation and ethanol distillation to obtain an extract; subjecting the extract to pressure reduction solidification, washing and filtration in sequence to obtain filtrate A; adding the filtrate A into acid liquor, and subjecting the mixture to precipitation, filtration, extraction and concentration to obtain a precursor; and subjecting the precursor to purification by acidified diatomite, and then drying to obtain the final product. The three-phase purification technology is used to remove macromolecular impurities and dark pigments in the dry rosemary leaves, and meanwhile, the effective components in the plant are completely reserved. Further, the diatomite is used for adsorption and purification treatment, which can not only effectively remove small molecular impurities and complex pigment in the rosmarinic acid, but also reduce the loss of the rosmarinic acid, so that the clear and transparent rosmarinic acid is obtained, and the yield of the product is improved.

This invention belongs to the field of feed additive technology, and particularly relates to a feed additive that reduces antibiotic resistance genes in animal feces, its preparation method, and its application. The feed additive comprises the following components in the indicated mass ratios: rosmarinic acid 10-15%, 5-O-caffeoylshikimic acid 10-15%, Lycopus lucidus flavonoids 8-12%, tea polyphenols 7-10%, DL-α-tocopherol 7-10%, hydroxypropyl-β-cyclodextrin 22-28%, microcapsule wall material 18-22%, EDTA-2Na 0.8-1.2%, and citrate-sodium citrate buffer 1.5-2.2%. This feed additive not only exhibits clear antibacterial activity against Escherichia coli and Salmonella, but also improves the growth performance of weaned piglets, reduces the diarrhea rate in weaned piglets, and decreases the abundance of antibiotic resistance genes in their feces, showing promising application prospects.

This invention discloses a composition for enhancing the disease resistance of frogs and its applications. The composition mainly consists of the core active peptide Peptide-3, astragalus polysaccharide, ginseng polysaccharide, prepared rehmannia root, and rosmarinic acid. Targeting "tiltosis and cataracts" in frogs caused by Elizabethanella miltiorrhiza, this invention works based on a synergistic mechanism of "targeted sterilization—immune warning—neural repair": Peptide-3 destroys the cell membrane of drug-resistant bacteria through a physical perforation mechanism to reduce pathogen load; plant polysaccharides induce non-specific immune warning in the body; prepared rehmannia root and rosmarinic acid synergistically scavenge free radicals, enhance SOD activity, and inhibit the expression of the pro-inflammatory factor TNF-α, precisely repairing damage to the central nervous system and eye tissues. Experiments show that the composition of this invention can increase the survival rate of diseased frogs to 92.4%, significantly reduce the incidence of tilted head and cataracts, and achieve a technological leap from single sterilization to comprehensive protection of the body.

A method for breeding blue crab after spawning, characterized in that the method comprises a blue crab post-spawning microcirculation preparation, wherein the blue crab post-spawning microcirculation preparation contains at least one of the following components and contents: rosmarinic acid with a content of 300-400 mg / L, jasmolinic acid with a content of 250-350 mg / L, oleuropein with a content of 250-350 mg / L, and terpene alcohol with a content of 200-300 mg / L. The blue crab post-spawning microcirculation preparation can significantly improve the growth level, nutrient transport capacity, metabolic waste capacity, tissue repair capacity and fat and energy storage capacity of the post-spawning female crab, and promote the weight gain and rejuvenation of the post-spawning blue crab.

The invention relates to the technical field of daily cosmetics, in particular to a natural plant composition for multi-effect skin care and a preparation method thereof. According to the principles of monarch, minister, assistant and guide and ascending, descending, sinking and floating, a formula comprising 15-20 parts of ginseng, 15-20 parts of dendrobium officinale, 10-15 parts of salvia miltiorrhiza, 10-15 parts of rhodiola rosea, 10-15 parts of rose, 5-10 parts of rosemary, 5-10 parts of dogwood, 5-10 parts of rhizoma bletillae, 5-10 parts of poria cocos, 5-10 parts of peony and 3-5 parts of liquorice is designed. The method comprises the following steps: respectively carrying out precise extraction by adopting three differential processes of steam distillation, ultrasonic alcohol extraction and low-temperature ultrasonic water extraction, then combining and refining, compounding auxiliary materials and carrying out two-stage filtration. According to the method, the limitation of traditional single extraction is broken through, efficient retention and synergistic effect of full-spectrum active ingredients are achieved, and the final product is fragrant in smell, integrates multiple effects of brightening, moistening and wrinkle resistance, and is good in stability and safety.