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2480 results about "Ethylenediaminetetraacetic acid" patented technology

Ethylenediaminetetraacetic acid (EDTA), also known by several other names, is a chemical used for both industrial and medical purposes. It was synthesized for the first time in 1935 by Ferdinand Münz.

Rapid acting and long acting insulin combination formulations

A combined rapid acting-long acting insulin formulation has been developed wherein the pH of the rapid acting insulin is adjusted so that the long acting glargine remains soluble when they are mixed together. In the preferred embodiment, this injectable basal bolus insulin is administered before breakfast, provides adequate bolus insulin levels to cover the meal, does not produce hypoglycemia after the meal and provides adequate basal insulin for 24 hours. Lunch and dinner can be covered by two bolus injections of a fast acting, or a rapid acting or a very rapid acting insulin. As a result, a patient using intensive insulin therapy should only inject three, rather than four, times a day. Experiments have been performed to demonstrate, the importance of the addition of specific acids to hexameric insulin to enhance speed and amount of absorption and preserve bioactivity following dissociation into the monomeric form by addition of a chelator such as EDTA. As shown by the examples, the preferred acids are aspartic, maleic, succinic, glutamic and citric acid. These are added in addition to a chelator, preferably ethylenediaminetetraacetic acid (EDTA). The results show that the citric acid formulation was more effective at dropping the blood glucose rapidly than the identical rapid acting formulation prepared with HCl in swine. Charge masking by the polyacid appears to be responsible for rapid insulin absorption. EDTA was not effective when used with adipic acid, oxalic acid or HCl at hastening the absorption of insulin. These results confirm the results seen in clinical subjects and patients with diabetes treated with the rapid acting insulin in combination with citric acid and EDTA.
Owner:ELI LILLY & CO

Rapid Acting and Long Acting Insulin Combination Formulations

A combined rapid acting-long acting insulin formulation has been developed wherein the pH of the rapid acting insulin is decreased so that the long acting glargine remains soluble when they are mixed together. In the preferred embodiment, this injectable basal bolus insulin is administered before breakfast, provides adequate bolus insulin levels to cover the meal, does not produce hypoglycemia after the meal and provides adequate basal insulin for 24 hours. Lunch and dinner can be covered by two bolus injections of a fast acting, or a rapid acting or a very rapid acting insulin. As a result, a patient using intensive insulin therapy should only inject three, rather than four, times a day. Experiments have been performed to demonstrate the importance of the addition of specific acids to hexameric insulin to enhance speed and amount of absorption and preserve bioactivity following dissociation into the monomeric form by addition of a chelator such as EDTA. As shown by the examples, the preferred acids are aspartic, glutamic and citric acid. These are added in addition to a chelator, preferably ethylenediaminetetraacetic acid (EDTA). The results show that the citric acid formulation was more effective at dropping the blood glucose rapidly than the identical rapid acting formulation prepared with HCl in swine. Charge masking by the polyacid appears to be responsible for rapid insulin absorption. EDTA was not effective when used with adipic acid, oxalic acid or HCl at hastening the absorption of insulin. These results confirm the results seen in clinical subjects and patients with diabetes treated with the rapid acting insulin in combination with citric acid and EDTA.
Owner:ELI LILLY & CO

Anti-bacterial hand-washing solution and preparation method thereof

The invention specifically relates to an anti-bacterial hand-washing solution and a preparation method thereof, belonging to the field of washing agents. The anti-bacterial hand-washing solution is mainly composed of fatty alcohol polyoxyethylene ether sodium sulfate, cocoamidopropyl betaine, alkyl glucoside, polyquaternary ammonium salt, fatty glyceride, humectant, mixed plant extract, tetrasodium ethylenediamine tetraacetate, sodium chloride, citric acid, jojoba oil, 1,2-pentanediol and essence. The preparation method comprises the following steps: dissolving fatty alcohol polyoxyethylene ether sodium sulfate, cocoamidopropyl betaine and fatty glyceride with water with a total amount of 70 to 80%; uniformly mixing jojoba oil, polyquaternary ammonium salt, humectant and alkyl glucoside; and mixing two mixed solutions obtained in the previous two steps, adding the rest components and carrying out uniform mixing under stirring. The anti-bacterial hand-washing solution provided by the invention has skin-care, skin-moistening, antibacterial, bacteriostatic, anti-allergy, soothing, anti-inflammatory and hand-microcirculation-improving effects and is a multifunctional hand-washing solution with strong sterilization and detergency capabilities and substantial skin-care and skin-moistening effects.
Owner:WALCH GUANGZHOU COMMODITY

Architectural ceramic prepared from industrial solid waste through dry method and process for preparing architectural ceramic

The invention discloses architectural ceramic prepared from industrial solid waste through a dry method and a process for preparing the architectural ceramic. The architectural ceramic comprises the following components in percentage by mass: 30-60% of solid waste, 40-70% of ceramic raw material and 1-3% of ceramic additive, wherein the ceramic raw material is selected from one or a composition of multiple of clay raw material, feldspar raw material or talc, and the ceramic additive is one or a combination of multiple of sodium tripolyphosphate, sodium silicate, ammonium chloride, ammonium citrate, sodium humate, sodium lignin sulfonate sodium, ethylenediamine tetraacetic acid disodium and edetic acid. After being pretreated, the granules of the solid waste are fine and are mixed evenly in a dry mixing manner and a spray drying manner and are directly used for pressing of green bricks or stored in a bin for standby, so that the ball milling energy consumption and the peptization cost are reduced, the humidification pelleting and fluidized bed drying procedures are omitted, the formula can be quickly adjusted according to the functional characteristics of the architectural ceramic, the process is simple and convenient to control, and the architectural ceramic has such good properties as heat preservation, thermal insulation and high strength.
Owner:FOSHAN OCEANO CERAMICS +1

Production method for spray-drying Chinese yam powder without using sulfur to protecting color

The invention relates to a production method for spray-drying Chinese yam powder without using sulfur to protecting color. The Chinese yam is prepared from fresh Chinese yam and is obtained by the steps of microwave enzyme deactivation, shelling, slicing, color protection, pulping, grinding, vacuum condensation, homogenization, spray-drying, vacuum packaging and microwave sterilization. The Chinese yam raw material is deactivated by microwave at temperature of 60 DEG C, cut to slice, and is soaked in sulfur-free color protection liquid containing phytic acid, Ethylenediaminetetraacetic acid disodium, vitamin C and citric acid, the color protection liquid and the Chinese yam slice is pulped together and is milled by a colloid mill, the Chinese yam slurry is concentrated by a vacuum condensation equipment until the content of solid is 15-25% and is homogeneously processed, homogenized liquid material is sprayed and dried by a centrifugal spray-drying machine, the obtained Chinese yam powder is packaged by vacuum and is sterilized by a microwave sterilization equipment to prepare the sulfur-free Chinese yam powder product. The invention has high production efficiency and low cost, the produced Chinese yam product has good color, high safety and complete nutrient composition, and can applied for field such as foodstuff, medicine and cosmetic product.
Owner:袁书林

Normal temperature formaldehyde removal catalysis material

The invention relates to a formula and a corresponding preparation technology of a normal temperature formaldehyde removal catalysis material, and belongs to the technical fields of normal temperature adsorption catalysis and air pollution treatment. The catalysis material is prepared by adopting a one-step co-precipitation process or a step-by-step dipping process to load active components with granular, cylindrical, spherical or honeycomb high-specific surface area shell activated carbon as a carrier, one or more non-noble metal salts as main active components, such as nitrate, sulfate or chloride of manganese, iron, cobalt, nickel, copper, zinc, lanthanum or cerium, one or more alkali metal/ alkaline earth metal salts as an inorganic additive, such as oxalate, nitrate, sulfate, acetate, carbonate and bicarbonate of sodium, potassium, magnesium, calcium, and ethylenediamine tetracetic acid/ethylenediamine tetraacetic acid salt, basic amino acid, polyamide monomer and polyurethane monomer as a nitrogen-containing organic additive. The normal temperature formaldehyde removal catalysis material has the characteristics of rapid capture, high efficiency catalytic oxidation and long working cycle, and can meet requirements of long-time effective removal of formaldehyde in indoor real environment.
Owner:江苏瑞丰科技实业有限公司

Preparation method of lithium ion battery negative electrode material spinel porous high-entropy oxide material

The invention discloses a preparation method of a lithium ion battery negative electrode material spinel porous high-entropy oxide material, and belongs to the field of inorganic oxide powder materials. The method is a low-temperature combustion synthesis method, and specifically includes the steps that metal nitrate is adopted as a metal source, one or a mixture of several of tartaric acid, citric acid, glucose, hexamine and ethylenediaminetetraacetic acid is used as a fuel, and by controlling the concentration of the metal salt raw material, the kind and the amount of the fuel, the kind andthe amount of a combustion improver and an ignition mode, characteristics of the grain size, the shape and the like of spinel ransition metal high-entropy oxide nano-powder are adjusted and controlled. According to the preparation method of the lithium ion battery negative electrode material spinel porous high-entropy oxide material, liquid-phase ingredients are adopted, molecular-level even mixing of the raw materials is ensured, and a stoichiometric ratio of the product is achieved; meanwhile the preparation method of the lithium ion battery negative electrode material spinel porous high-entropy oxide material has the advantages of being energy-saving, high in production efficiency, environmentally friendly, free from complex post-treatment and the like, and the prepared high-entropy oxide powder is high in purity, small in grain size and even in distribution, and has high initial discharge capacity and good cycle performance.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY

Ester type fire-resistant hydraulic fluid and preparation method thereof

InactiveCN103013635AInhibition of catalytic oxidationImprove stabilityLubricant compositionPhosphoric acidTriazole derivatives
The invention relates to an ester type fire-resistant hydraulic fluid. The hydraulic fluid comprises the following raw materials by weight percent: 95-99% of base oil, 1.0-5.0% of diphenol propane, 0.005% of dimethylsilicone fluid or dimethylsilicone grease, 0.05% of tricresyl phosphate, 0.1% of benzotriazole, 100 parts per million (PPM) demulsifying agent T1001 or LZ5957 and 0.2-0.3% of triazole derivative, thiadiazole derivative, N-salicylidene ethylamine, N, N'-bis(salicylidene)ethylenediamine, N, N'-bis(salicylidene)propylene diamine or ethylenediamine tetraacetic acid. A preparation method of the ester type fire-resistant hydraulic fluid comprises the following steps of sufficiently and evenly stirring various materials at room temperature according to a formula, and then filtering. The ester type fire-resistant hydraulic fluid has the beneficial effects that the high temperature use performance of the product is greatly improved, the service life of a hydraulic system and the oil changing period of oils are prolonged, and the ester type fire-resistant hydraulic fluid has a good flame-retardant effect and is safe to use. The preparation method has the advantages that operation is convenient, technology and equipment are simple, energy consumption is low, cost is low, and the like.
Owner:ANLU AOSEN PETROCHEM

Multifunctional adsorption particles capable of treating industrial organic wastewater with imbalance of nitrogen and phosphorus and preparation method thereof

InactiveCN103611514AHas the function of slow-release nitrogen and phosphorusSimple preparation processOther chemical processesWater/sewage treatment by sorptionSorbentNitric acid
The invention discloses multifunctional adsorption particles capable of treating industrial organic wastewater with imbalance of nitrogen and phosphorus and a preparation method thereof. The preparation method comprises the steps of preparing a mixed solution F from a NH4HCO3 solution, a Ca(NO3)2 solution, a (NH4)2HPO4 solution, a NaOH solution, a nitric acid solution, a urea water solution and an ethylenediaminetetraacetic acid calcium sodium solution; preparing a mixed solution L from urea and a formaldehyde water solution; preparing a mixed solution M from a styrene chloroform solution, a divinyl benzene chloroform solution and an azobisisobutyronitrile chloroform solution; dropping the mixed solution L into the mixed solution M to obtain a mixed solution N; dropping the mixed solution F into the mixed solution N to obtain a mixed solution O; dropping the mixed solution O into a polyvinyl alcohol solution to obtain a mixed solution P; adding the polyvinyl alcohol solution into the mixed solution P, and performing centrifugal separation to obtain the multifunctional adsorption particles capable of treating the industrial organic wastewater with imbalance of nitrogen and phosphorus. The preparation process disclosed by the invention is simple, and a prepared multifunctional adsorbent has the function of nitrogen and phosphorus sustained release and the function of adsorbing pollutants in industrial organic wastewater.
Owner:BEIJING NORMAL UNIVERSITY
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