The invention discloses a shale gas well CO2 and slickwater mixing fracturing technology, and relates to the technical field of shale gas exploiting, in particular to the mixing fracturing technology by adopting CO2 and slickwater. In the construction process, a fracturing truck, a fracturing blender truck, a CO2 tank truck, a CO2 pump truck, a measuring truck, a fracturing manifold truck, an acid tank, propping agents and a liquid storage pot group need to be prepared, the fracturing manifold truck is provided with a low-pressure manifold and a high-pressure manifold, and the measuring truck is provided with a monitoring instrument, and the technology is characterized by comprising seven steps of doing well site planning, pressure testing, acid liquid processing, CO2 fracturing construction, slickwater fracturing construction, well closing after fracturing, and flow opening and flowback after fracturing. The shale gas well CO2 and slickwater mixing fracturing technology has the advantage that the shale gas exploiting method which is low in cost, low in relative construction difficulty, small in damage to a shale gas reservoir stratum and efficient is achieved.