650results about "Analysis using nuclear magnetic resonance" patented technology

The invention relates to a metabolic marker for diagnosing diabetic secondary osteoporosis and application of the metabolic marker, and belongs to the technical field of biological medicine. The method comprises the following steps: firstly, screening out obviously different metabolites between osteoporosis (DOP) and osteoporosis-free groups (DM) in diabetic patients; and secondly, screening out significant difference metabolites between the primary osteoporosis patient and the healthy control group, and excluding the intersection of the two groups of difference metabolites to obtain metabolites which exclude the influence of the primary osteoporosis. Metabolic markers, namely cytosine nucleotide, ketoglutaric acid and triethylamine, are obtained through further screening, and when the three metabolic markers are independently used, AUCgt; the AUC during combined use is 0.99, so that the limitation that the sensitivity of the traditional bone mineral density detection on the osteoporosis recognition in the diabetic population is insufficient is effectively made up.

A method for material detection may include extracting, from a material database, a resonance frequency for the target material. The method may further include comparing an application type to entries in a scan database. The scan database may store pre-defined scanning patterns and corresponding application types. The method may include extracting, from the scan database, a scan sequence for the application type. Also, the method may include instructing a gimbal to follow positions in the scan sequence. The method may also include transmitting into an environment an RF signal when the gimbal is at the positions in the scan sequence. The method may further include receiving a response signal from the environment. The method may include generating a haptic feedback to indicate a directionality or a proximity to the target material. The method may include analyzing the response signal for resonance characteristics that indicate a presence of the target material.

The embodiment of the invention discloses a scanning NV probe microscope which comprises an atomic force microscopy system used for detecting surface topography information of a sample and an optical detection magnetic resonance system used for detecting surface magnetic field distribution information of the sample, and the atomic force microscopy system comprises a vibration arm and a diamond probe. The optical detection magnetic resonance system comprises an NV color center, a transition excitation light path and a fluorescence detection light path; a sample to be scanned and the transition excitation light path are respectively positioned on two opposite sides of the diamond probe, and the transition excitation light path and the fluorescence detection light path are positioned on the same side of the diamond probe; a first metal coating film is arranged on one side, close to the sample, of the diamond probe and is used for blocking surface fluorescence of the sample. According to the scanning NV probe microscope provided by the embodiment of the invention, the metal coating is arranged at the bottom of the diamond probe to block stray fluorescence from the surface of the sample, so that the problems of low magnetic field imaging signal-to-noise ratio and limited measurement precision of the existing scanning NV probe microscope are solved.

The invention discloses a sapphire window-based nuclear magnetic resonance device and a coal seam free gas volume correction method, the sapphire window-based nuclear magnetic resonance device comprises a computer, a gas cylinder assembly, a nuclear magnetic bearing platform, a coal sample holder, a stable displacement pump and a laser emitter, the gas cylinder assembly is connected with a left end inlet of the coal sample holder, and the coal sample holder is arranged on the nuclear magnetic bearing platform; a sapphire window is arranged on the coal sample holder, laser emitted by the laser emitter faces the sapphire window to observe a cylindrical coal sample in the coal sample holder, an outlet at the right end of the coal sample holder is connected with a test pipeline, and the coal sample holder is connected with a confining pressure control pipeline. Advanced technologies such as nuclear magnetic resonance and laser scanning are applied to the free gas content simulation experiment of the coal bed gas reservoir, and the tested data are more accurate. The device can also be used for permeability testing, methane adsorption experiments, displacement experiments and the like, test results are used for evaluating distribution characteristics of free gas in geological media such as coal seams and shale, and theoretical data support is provided for energy development in China.

The invention relates to the technical field of oil-gas field development and reservoir protection, in particular to a low-permeability tight reservoir clay stabilizer mixing amount optimization method, which comprises the following steps: firstly, enabling a rock sample and clay stabilizer solutions with different concentration gradients to generate imbibition to obtain nuclear magnetic signal peak areas corresponding to different imbibition moments; obtaining a liquid inlet amount change rate K sequence and a permeability change rate K sequence; then obtaining a first weight coefficient alpha and a second weight coefficient beta; and finally, calculating a comprehensive decision index CDI sequence. Taking the concentration of the clay stabilizer solution corresponding to the permeability change rate K less than or equal to the maximum permeability damage threshold value Kmax and the minimum value of the comprehensive decision index CDI as the optimal clay stabilizer concentration; according to the method, accurate and differentiated optimization of the mixing amount of the clay stabilizer is achieved, the defects of an existing static evaluation method are overcome, and the method has important significance for protecting a low-permeability tight reservoir and improving the recovery ratio.

The invention relates to the technical field of oil exploitation and processing, in particular to a logging-based two-dimensional nuclear magnetic resonance low-permeability conglomerate fluid property identification method, which comprises the following steps of: obtaining the sum of original fluid areas in an original state of a low-permeability conglomerate core through two-dimensional nuclear magnetic resonance; obtaining the sum of manganese-saturated fluid areas of the low-permeability conglomerate core in a manganese-saturated state through two-dimensional nuclear magnetic resonance; according to the sum of the original fluid areas of the low-permeability conglomerate core in the original state and the sum of the manganese-saturated fluid areas of the low-permeability conglomerate core in the manganese-saturated state, the remaining oil index of the low-permeability conglomerate is obtained; and determining the fluid property of the low-permeability conglomerate reservoir according to the remaining oil index of the low-permeability conglomerate. According to the method, the residual oil index of the low-permeability conglomerate reservoir is established in an intuitive representation mode, the calculation formula of the residual oil index is based on extraction of parameter characteristics in a two-dimensional nuclear magnetic resonance original state and a manganese-saturated state, and the low-permeability conglomerate fluid property can be effectively recognized.

The invention belongs to the technical field of oil and gas reservoir engineering and multiphase seepage dynamic monitoring, relates to a characterization method of seepage behaviors of multiphase fluid in a porous medium, and particularly provides a dynamic construction method of a multiphase displacement capillary pressure-saturation relationship based on nuclear magnetic resonance. Comprising the following steps: S1, acquiring a low-field nuclear magnetic resonance relaxation spectrum of a porous medium in a gas-water two-phase displacement process; s2, determining two-phase fluid interfacial tension, a wetting contact angle and a rock surface relaxation rate; s3, determining the dynamic cut-off relaxation time of the displacement stage; s4, calculating equivalent capillary pressure; the residual water saturation is calculated, and the equivalent capillary pressure is the capillary pressure corresponding to the current displacement stage and is used for constructing a capillary pressure-saturation curve. According to the method, the capillary pressure change in the porous medium can be obtained only through spectral analysis without a centrifugal or mercury injection experiment.

The invention discloses an intelligent processing system for agricultural grain harvesting, and the system comprises a plurality of acoustic emission sensing units which are distributed in an array manner, are coupled to a threshing part, and are used for monitoring the micro-damage of grains; and the integrated multi-mode sensing unit is arranged on the grain conveying part and comprises a transmission type sensor for acquiring grain internal structure data, a spectrum sensor for acquiring grain surface chemical component data, a volatile organic compound sensor and a body moisture sensor. The system also includes a central data processor configured to: calculate a micro-damage index; generating a grain quality map; generating corruption risk features; and generating a system control signal for the agricultural harvesting device based on at least one of the microdamage index, the grain quality map, and the spoilage risk feature. The problems that internal damage cannot be monitored in real time, internal and external defects cannot be distinguished and moisture interference cannot be overcome in a harvesting field are solved.

The present invention refers to an in vitro method for the diagnosis and / or prognosis of multiple sclerosis.

The invention belongs to the technical field of coal bed gas exploitation and carbon dioxide geological storage, and relates to a coal bed carbon dioxide injectability evolution whole process simulation device and method, and the device comprises a true triaxial stress loading system, a temperature control system, a multi-mode gas injection system, a monitoring system, and a data processing system. The deep stratum stress state and the stratum temperature field are simulated, constant-pressure and constant-current mode carbon dioxide is injected into the true triaxial stress loading system to carry out groutability attenuation and recovery simulation, and nitrogen and pulse mode injection is switched to carry out temperature change regulation and control, phase change regulation and control and frequency change regulation and control so as to simulate groutability improvement. According to the method, a whole-process evolution mechanism of attenuation-recovery-improvement of carbon dioxide groutability is realized, meanwhile, data acquisition and permeability and stress calculation are performed through a monitoring system and a data processing system, and rapid conversion from original data to core parameters is realized; and accurate experimental data support is provided for on-site injection parameter optimization and regulation and control technology research and development.

The invention discloses a double-layer acrylic acid OCA optical adhesive for a folding screen and a structural characterization method of the double-layer acrylic acid OCA optical adhesive, and belongs to the technical field of optical adhesives. The OCA optical cement comprises an upper high-creep layer and a lower high-recovery layer, and an intersoluble cross-linked structure is formed on the interface of the two layers through a gradient curing process. The upper layer formula contains 70-90 parts of 2-ethylhexyl acrylate and 10-30 parts of hydroxy butyl acrylate; the formula of the lower layer comprises 20-35 parts of isobornyl acrylate, 50-70 parts of 2-ethylhexyl acrylate and 5-15 parts of hydroxy butyl acrylate. And the longitudinal crosslinking density gradient is represented by adopting a unilateral nuclear magnetic resonance depth analysis technology. The contradiction between high adhesion and high resilience of the folding screen OCA is solved, high light transmittance, low haze, high stripping force and high creep recovery rate are achieved, and the resistance change rate is remarkably reduced after dynamic folding.

The invention provides a nuclear magnetic resonance system and method for simulating high-temperature and high-pressure conditions. The nuclear magnetic resonance system for simulating the high-temperature and high-pressure conditions comprises a core rotor module, a temperature control and heat dissipation module, a signal enhancement and detection module and a high-pressure environment module, and the core rotor module is used for solving the problems that a traditional rotor is low in precision, short in service life and poor in adaptability. According to the nuclear magnetic resonance system and method for simulating the high-temperature and high-pressure conditions, the tolerance pressure of a sample cavity is improved, extreme high-pressure scenes such as deep sea and a mantle can be simulated, the sealing life is prolonged, the sample pollution rate is reduced, the detection accuracy is improved, the pressure monitoring delay is shortened, the pressure fluctuation is reduced, and the environmental stability is improved; the deviation of different batches of detection results is reduced to be within 2%, the system has an overpressure automatic pressure relief function, the safety of the system is improved, the system is adaptive to different types of highly corrosive samples, and the detection types are expanded.

The embodiment of the invention discloses a method and device for testing foam seepage characteristics of a heterogeneous porous medium, electronic equipment and a storage medium, and relates to the technical field of fluid mechanics and nuclear magnetic resonance. The method comprises the steps that a heterogeneous porous medium sample with a clear permeability level difference is prepared, and the permeability level difference of the heterogeneous porous medium sample is determined; setting test parameters according to the permeability level difference of the sample, calibrating imaging parameters of the low-field nuclear magnetic resonance equipment, and setting a weighting mode; performing foam flooding treatment on the sample according to the set injection parameters, acquiring a spectrum of the sample according to the test parameters when foam is injected into a set amount, and acquiring nuclear magnetic imaging of the sample through low-field nuclear magnetic resonance equipment according to imaging parameters and a weighting mode; according to the relaxation characteristic of the spectrum, the main peak endpoint value is used for dividing the pore channel, the foam sweep degree is calculated according to the spectrum peak area of the spectrum, and the foam plugging strength is calculated according to the signal amplitude of nuclear magnetic imaging. According to the method, the problems of poor visualization adaptability and lack of evaluation systems in the prior art are solved.

The application discloses a raw coal pore detection method, device, system and medium based on nuclear magnetic resonance. The method comprises the following steps: obtaining relaxation time distribution data of each coal sample based on nuclear magnetic resonance T2 test; obtaining total integral areas of a plurality of nuclear magnetic resonance T2 spectra corresponding to each coal sample based on the relaxation time distribution data of each coal sample; performing statistical analysis on the relative standard deviation of the total integral areas of each coal sample to obtain the relative standard deviation corresponding to each coal sample; and determining the coal sample parameters of a target coal sample for detecting the pore structure of the raw coal according to the coal sample parameters of the coal sample corresponding to the relative standard deviation satisfying the preset condition. The raw coal pore detection method provided by the application can determine the target coal sample by selecting the coal sample parameters of the coal sample satisfying the preset condition, so that the result of the nuclear magnetic resonance T2 test for detecting the pore structure of the raw coal is more accurate and stable.

The present application provides a kind of shale oil oil saturation measurement method, device, storage medium and electronic equipment, belong to petroleum exploration technical field.The shale oil oil saturation measurement method includes: obtaining two-dimensional nuclear magnetic T1-T2 spectrum, the two-dimensional nuclear magnetic T1-T2 spectrum is using the first pulse sequence of multiple waiting time, fluid distribution in the field core object is identified based on the two-dimensional nuclear magnetic T1-T2 spectrum, and the distribution characteristics of multiple core fluids are obtained.Based on the distribution characteristics of various core fluids, the oil saturation of various core fluids is calculated according to the preset saturation calculation model to obtain the oil saturation of shale oil.The oiliness can be qualitatively and quantitatively evaluated, the oil saturation can be accurately calculated, the oiliness can be quantitatively evaluated, and the well site rapid interpretation and evaluation can be realized.

The invention relates to the technical field of near-well region reservoir development, and particularly discloses a method for evaluating the permeability of pilot production near-well region reservoirs by drilling and production working fluid invasion, which comprises the following steps: selecting shallow surface layer muddy silt sediment and fine silt of a target sea area as media, and preparing an overlying stratum core and multiple groups of parallel cores with different porosity and water saturation; putting the sample tube into a holder with a nuclear magnetic cavity, introducing methane gas to generate hydrate, and monitoring pressure and nuclear magnetic signals to obtain a hydrate reservoir core; reversely injecting cold water to test the permeability before liquid phase invasion; injecting a microbial solution and a nutritive salt solution for culture and reinforcement, testing permeability before and after reinforcement, and analyzing the influence; drilling fluid, well completion fluid, reservoir transformation working fluid, transformation working fluid carrying permeation enhancing materials and ethylene glycol mining fluid are injected under the same conditions to simulate invasion, nuclear magnetic signals are monitored, the permeability after invasion is tested, and the damage degree before and after reinforcement and the anti-invasion effect are compared.

Provided are: a method and a device for determining the degree of deterioration of a shaping powder which enable shaped objects to be inhibited from decreasing in mechanical property or dimensional accuracy; a method and a device for producing a reclaimed shaping powder; and a method and a device for producing a three-dimensional shaped object.　A dispersion obtained by dispersing a shaping powder in a solvent is examined for 1H nucleus spin-spin relaxation time T2 using a pulsed NMR device. The specific surface area of the shaping powder is calculated on the basis of the 1H nucleus spin-spin relaxation time T2 of the dispersion and the 1H nucleus spin-spin relaxation time T2 of the solvent. The specific surface area of a shaping powder is apparently increased or reduced by preheating within a powder bed or by heat due to irradiation with laser light or an electron beam. The specific surface area of the shaping powder can hence be used as an index to the degree of deterioration of the shaping powder.

An article includes a cylinder of single crystal sapphire for use during solid state nuclear magnetic resonance (SSNMR) measurements. The axis of the cylinder is aligned with an axis of symmetry of the single crystal. The cylinder is configured to rotate at a known angle and known fraction of an angular velocity as the sample during operation of the SSNMR system. In some uses, a current angle of a stator is determined based on separation of peaks in a measured signal from aluminum atoms in the sapphire crystal. Stator orientation is adjusted until the current angle is within a desired tolerance of a target angle, including one different from a magic angle.

The present application relates to rock mechanics, seepage mechanics and unconventional natural gas development technical field, specifically relates to a multi-scale pore and fracture connectivity characterization method of coal body under variable confining pressure based on nuclear magnetic resonance, comprising the following steps: confining pressure saturation and benchmark acquisition; constant pressure displacement and in-situ monitoring: keeping confining pressure constant, injecting nitrogen displacement under constant pressure difference, testing T2 spectrum in-situ at preset time node, obtaining residual water integral area, and determining displacement equilibrium until spectrum shape is stable; multi-stage confining pressure experiment; multi-scale connectivity calculation; compaction-damage stage determination, the present application divides nuclear magnetic resonance T2 spectrum into three scale intervals of micro-pore, medium-pore, large-pore and fracture, calculates the connectivity of each scale through relative connectivity, can distinguish the differential influence of confining pressure on pores and fractures of different scales, reveals the asynchronous evolution law of micro-pore network and fracture system, and provides fine data support for deep coal and rock seepage mechanism research.

Embodiments of the present disclosure provide for systems and methods of making, processing, and purifying hyperpolarized fluid samples and fractions thereof as well as detecting and using the hyperpolarized fluid samples. The present disclosure provides for methods and systems of making hyperpolarized fluid sample (e.g., hyperpolarized target molecules), which can be analyzed using a nuclear magnetic resonance (NMR) detection device.

The invention belongs to the technical field of reservoir pore structure characterization, and relates to a nuclear magnetic resonance T2 spectrum pore diameter conversion method based on a least square method and mercury injection data. The method comprises the following steps: interpolating and fitting cumulative distribution frequency of nuclear magnetic resonance about relaxation time to obtain a relationship between the cumulative distribution frequency of the relaxation time and the radius of a mercury injection pore; interpolation and fitting are carried out on the cumulative distribution frequency of the high-pressure mercury injection relative to the pore radius, and the relation between the cumulative distribution frequency of the pore radius and the mercury injection pore radius is obtained; establishing an error function based on the relationship between the cumulative distribution frequency of the relaxation time and the mercury injection pore radius and the relationship between the cumulative distribution frequency of the pore radius and the mercury injection pore radius; establishing a conversion function for converting the cumulative distribution curve of the nuclear magnetic resonance T2 relaxation time into a cumulative distribution curve of a high-pressure mercury injection pore throat radius; and substituting the error function into a conversion function to solve a conversion coefficient in the conversion function, and completing nuclear magnetic resonance T2 spectrum aperture conversion.

According to one embodiment, a polishing pad includes a polishing layer comprising a urethane-based prepolymer and a curing agent, wherein the spin-lattice relaxation time (T1) and spin-spin relaxation time (T2) measured using TD-NMR for the polishing layer satisfy Equations 1 and 2, respectively, and thus can improve the performance of the polishing pad.

The invention belongs to the technical field of reproductive medicine and clinical metabolism intervention, and particularly relates to a group of markers for diagnosing unexplained recurrent abortion and application thereof. Aiming at the clinical pain point that unexplained recurrent abortion (URSA) lacks accurate metabolic typing diagnosis indexes and targeted treatment means, based on detection of a large number of clinical samples and verification of cell experiments, direct association between down-regulation of levels of choline related metabolites and trimethylamine oxide (TMAO) of decidua tissues and the RSA is disclosed for the first time; the core effect of TMAO in-situ synthesis of decidua stromal cells (DSC) in regulation and control of the decidualization process is determined; meanwhile, an RSA indication screening system of joint detection of serum creatinine and decidua choline metabolism is constructed, a targeted TMAO targeted intervention scheme is formed in a matched mode, a diagnosis and treatment closed loop of RSA from precise typing to targeted treatment is achieved, and a brand new technical path is provided for clinically solving the URSA diagnosis and treatment problem.

A device for inserting a sample into a sealed enclosure includes: a sample carrier for holding the sample; an insertion rod including an elongate portion for bearing the sample carrier; a transfer airlock including an outer door to close in a watertight manner and to open onto an environment outside the sealed enclosure, an inner door to close in a watertight manner and to open onto the inside of the sealed enclosure, and a sealed chamber defined between the outer door and the inner door when they are in the sealed configuration, the sealed chamber being able to accommodate the sample carrier inserted by the insertion rod; and a system for purifying the contained fluid medium, the sample carrier, and the sample which are accommodated in the sealed chamber.

The present application relates to the technical field of nuclear magnetic resonance analysis, and particularly relates to a magnetic resonance signal three-dimensional spectrum feature recognition and analysis method.The method comprises the following steps: acquiring a multi-channel time-domain magnetic field signal sequence through a three-dimensional sensing array; performing frame windowing processing and fast Fourier transform on the sequence to construct a complex spectrum matrix; decoupling the matrix in the complex domain by using a statistical independence criterion, eliminating the arrangement ambiguity introduced by the frequency domain transform through sub-band division, component extraction and spatial response consistency judgment, and restoring to obtain independent spectrum component signals corresponding to different radiation source regions; calculating the physical center coordinates of each radiation source region in combination with the array spatial coordinates, and then constructing a three-dimensional spectrum feature fingerprint of space-frequency domain fusion; and finally recognizing the state feature of the to-be-tested subject according to the matching deviation degree of the fingerprint and the standard feature library.The present application solves the problems of multi-source magnetic signal space coupling and frequency domain stripping, and improves the accuracy of weak feature recognition.

The invention relates to the technical field of oil and gas reservoir damage evaluation, in particular to a method and device for calculating irreducible water saturation of a tight sandstone reservoir, electronic equipment, a storable medium and a computer program product. The method comprises the following steps: acquiring a pore distribution curve of a compact sandstone sample; based on the pore distribution curve of the compact sandstone sample, determining the capillary bound water content of different pressure differences of the compact sandstone reservoir; carrying out total rock and clay mineral analysis on the compact sandstone sample to obtain the content of the clay bound water in the compact sandstone reservoir; and obtaining the irreducible water saturation of the tight sandstone reservoir based on the capillary irreducible water content and the clay irreducible water content. According to the method, the relationship between the absolute content, the pore distribution, the stress distribution and the interfacial tension of the clay mineral and the irreducible water saturation is established, so that qualitative and quantitative analysis on the irreducible water saturation is quickly and accurately performed.

This invention relates to the field of unconventional oil and gas development technology, and to a device and method for quantitatively evaluating the permeability enhancement caused by oxidative thermal stress in shale oil. The former includes a triaxial core holder housed within a constant-temperature chamber, and confining pressure injection system, oxidation medium injection system, detection medium injection system, gas collector, upstream storage tank, downstream storage tank, chromatograph, and acoustic emission sensor spaced apart outside the chamber. This application provides a dynamic multi-field coupled physical simulation system capable of simulating real formation conditions. By collecting pressure, product composition, acoustic signals, and nuclear magnetic resonance relaxation data, it utilizes a mathematical model for dynamic inversion of porosity and permeability using the pressure pulse attenuation method. It integrates acoustic emission RA-AF source identification and nuclear magnetic resonance fractal evaluation to analyze the multi-field coupling effects of thermal, flow, force, and chemical fields generated during air injection, and quantitatively evaluates the degree of improvement in shale permeability and pore structure caused by oxidative expansion.

The invention discloses an in-situ quantification and multi-scale positioning characterization method for CO2 injection oil displacement recombination analysis, and relates to the technical field of petroleum and natural gas exploration and development, and the method comprises the following steps: initial state calibration and reference acquisition; gas injection displacement and dynamic damage introduction; carrying out in-situ thermal remelting treatment; and performing multi-dimensional quantitative evaluation. The method has the beneficial effects that an'in-situ thermal remelting 'strategy is introduced, and the absolute mass of the precipitate can be directly calculated by establishing the relationship between the remelting state total signal Shot and the precipitation state total signal Scold; a multi-scale characterization system of micro pores and macroscopic cores is established, and the specific pore diameter interval of blockage is accurately identified by using the pore diameter resolution capability of the T2 spectrum; and by adopting an in-situ MRI (Magnetic Resonance Imaging) + quantitative matrix correction technology, non-destructive and full-vision-field monitoring on precipitate distribution is realized, and the spatial distribution rule of the precipitates in the rock core is intuitively revealed.

The invention provides a shale in-situ conversion physical property full-period evolution identification characterization method, and belongs to the technical field of shale in-situ conversion, the method comprises the following steps: selecting a shale sample, determining basic parameters, heating according to a preset heating rate under preset confining pressure, pore pressure and fluid boundary conditions, and carrying out online monitoring and staged sampling to obtain dynamic evolution parameters; in the identification evolution stage, candidate boundary confidence is calculated according to an evidence fusion theory and then combined with a preset stage semantic rule, conflict resolution is carried out by adopting a hierarchical priority strategy to generate a stage division result, uncertainty quantification is carried out by adopting an active learning strategy in combination with Gaussian process regression, and experimental temperature points are encrypted; and training a physical information constraint artificial intelligence prediction model and outputting a physical property dynamic evolution curve. The technical problem that the boundary of the physical property evolution stage in the shale in-situ conversion process is difficult to accurately identify is solved.