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Ontology for database design and application development

A system and method lets a user create or import ontologies and create databases and related application software. These databases can be specially tuned to suit a particular need, and each comes with the same error-detection rules to keep the data clean. Such databases may be searched based on meaning, rather than on words-that-begin-with-something. And multiple databases, if generated from the same basic ontology can communicate with each other without any additional effort. Ontology management and generation tools enable enterprises to create databases that use ontologies to improve data integration, maintainability, quality, and flexibility. Only the relevant aspects of the ontology are targeted, extracting out a sub-model that has the power of the full ontology restricted to objects of interest for the application domain. To increase performance and add desired database characteristics, this sub-model is translated into a database system. Java-based object-oriented and relational application program interfaces (APIs) are then generated from this translation, providing application developers with an API that exactly reflects the entity types and relations (classes and methods) that are represented by the database. This generation approach essentially turns the ontology into a set of integrated and efficient databases.
Owner:KYNDI

Flexible visually directed medical intubation instrument and method

A flexible medical intubation instrument provided for placement into an animal or human patient comprises a catheter with at least a pair of longitudinally extending lumens or channels including a sensor and/or actuator channel and a working channel. In the sensor/actuator channel is provided a fixed or slideably removable sensor cable having a sensor for sensing a characteristic or condition including any of the following: a visual sensor for optical viewing, a chemical sensor, a pH sensor, a pressure sensor, an infection sensor, an audio sensor, or a temperature sensor. The sensors are coupled by the sensor/actuator cable through light transmission, electric current, or radio transmission to a viewing instrument or other output device such as a meter or video screen for displaying the condition that is sensed within the body of the patient while the flexibility of the composite structure comprising the catheter and cable enable the entire instrument to flex laterally as it moves through curved passages or around obstructions during insertion or removal. While making observations through the sensor channel, the working channel simultaneously functions as a drain or an irrigation duct, a feeding tube, or to provide a passage for the insertion of one or a succession of surgical devices such that the catheter serves as a protective artificial tract or liner as surgical devices are inserted and removed through it in succession so as to minimize tissue trauma, infection, and pain experienced by the patient. The instrument can be used in urology, as well as a visually directed nasogastric tube, as a visually directed external gastrostomy tube, or as a visually directed internal gastric tube or percutaneous endoscopic gastrostomy tube and in other applications.
Owner:PERCUVISION

Feature quantification from multidimensional image data

Techniques, hardware, and software are provided for quantification of extensional features of structures of an imaged subject from image data representing a two-dimensional or three-dimensional image. In one embodiment, stenosis in a blood vessel may be quantified from volumetric image data of the blood vessel. A profile from a selected family of profiles is fit to selected image data. An estimate of cross sectional area of the blood vessel is generated based on the fit profile. Area values may be generated along a longitudinal axis of the vessel, and a one-dimensional profile fit to the generated area values. An objective quantification of stenosis in the vessel may be obtained from the area profile. In some cases, volumetric image data representing the imaged structure may be reformatted to facilitate the quantification, when the structural feature varies along a curvilinear axis. A mask is generated for the structural feature to be quantified based on the volumetric image data. A curve representing the curvilinear axis is determined from the mask by center-finding computations, such as moment calculations, and curve fitting. Image data are generated for oblique cuts at corresponding selected orientations with respect to the curvilinear axis, based on the curve and the volumetric image data. The oblique cuts may be used for suitable further processing, such as image display or quantification.
Owner:GENERAL ELECTRIC CO
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