The invention discloses an intelligent positioning method of mine microquake sources, which is a microquake resource intelligent positioning system which comprehensively considers various influencing factors and targets, and integrates with sensors distribution-noise wave filtration-microquake source positioning analysis-three-dimensional display in to a whole. The method realizes the real-time analysis and the forecast of the incubation, the development and the occurrence of mine underground geological disaster through a self-developed procedure, solves the defects that the traditional sensors distribution method is not systematic, the noise wave filtration is incomplete, the microquake wave speed model is not exact and the positioning method is easily diffused, and has the characteristics of friendly operation interface, good noise wave filtration performance, exact, convenient and fast microquake source positioning analysis, visual and pictorial result display, and wide application range. The method has wide application value in the fields of mineral engineering, water conservancy and electric power engineering, petroleum engineering, soil engineering and underground engineering and the like.