169 results about "Polyhexamethylene biguanide hydrochloride" patented technology

A cleaning and biocidal composition in liquid form comprising a solvent, a polymeric biguanide, a single quaternary ammonium salt, a sequestrant, and at least one surfactant. The composition comprising the solvent including water, the polymeric biguanide including a polyhexamethylene biguanide hydrochloride, the quaternary ammonium salt including a didecyldimethyl ammonium chloride, the sequestrant including an amino acid chelating agent selected from the group consisting of: ethylenediaminetetraacetic acid, nitrilotriacetic acid, tetrasodium ethylenediaminetetraacetic acid, or mixtures thereof, the surfactant including a non-ionic surfactant and an amphoteric surfactant.

The invention is an active ingredient combination comprising polyhexamethylenebiguanidine hydrochloride and distearyldimethylammonium chloride and a cosmetic or dermatological formulation comprising polyhexamethylenebiguanidine hydrochloride and distearyldimethylammonium chloride. The invention also includes methods of fighting or preventing dermatological harm comprising applying to the skin a cosmetic or dermatological formulation comprising polyhexamethylene biguanidine hydrochloride and distearyldimethylammonium chloride. The invention also includes methods of preventing decay of organic substances in a formulation, comprising adding to said formulation polyhexamethylene biguanidine hydrochloride and distearyidimethylammonium chloride.

The invention relates to a method for preparing an uramine-type macromolecule anti-bacterial agent, comprising two steps as follows: A, mixing any one solution of guanidine hcl, Polyhexamethyleneguanidine chloride and polyhexamethylene biguanide hydrochloride with maleic anhydride solution; introducing nitrogen for constant-temperature water bath reaction to obtain functional uramine salt; B, mixing functional uramine salt solution with acrylamide and / or styrene for constant-temperature water bath reaction to obtain ivory-white stringy liquid; depositing soft white solid with solvent for vacuum drying to obtain ivory-white bulk uramine-type copolymer, i.e, uramine-type macromolecule anti-bacterial agent. The uramine-type macromolecule anti-bacterial agent has remarkable effect and simple synthesis process, ensures that the anti-bacterial group is hard to move and the processing thermal stability is excellent through copolymerization on macromolecule long chain. The invention can be widely used in fields of plastic, dope, powder dope, rubber, wood plastic, rubber plastic, spinning, water processing, and the like.

The invention relates to a composition for killing microbes, which is mainly used for hand antisepsis, surgical hand antisepsis and antisepsis of skins and mucosa and can be also used for killing the microbes at the surfaces of the articles; polyhexamthylene guanidine hydrochloride and ethanol are adopted as main active fungicide ingredients to be combined with a fungicide synergistic agent isopropanol, wherein the concentration of the ethanol is 79-467 g / L, the concentration of the polyhexamthylene guanidine hydrochloride is 0.01-15 g / L and the concentration of the isopropanol is 3-54 g / L; meanwhile, a moisturizer, a stabilizing agent, a thickening agent and other agents can be added as needed to obtain different dosage forms; and the composition has the advantages of good fungicide effect, high speed, no washing, high stability, reduction of skin irritation of the product and functions of protecting and moisturizing skins.

The invention provides a disinfecting detergent and a preparation method thereof. The disinfecting detergent contains didecyldimethylammonium chloride, didecyldimethylammonium bromide, poly(hexamethylene biguanide) hydrochloride, dodecyldimethylbenzylammonium chloride, fatty alcohol-polyoxyethylene ether (9), fatty alcohol polyoxyethylen ether (7), fatty alcohol polyoxyethylen ether (8), alkyl polyglucoside, alkanolamides of fatty acids, lauramidopropyl betaine, essence, citric acid monohydrate food grade and deionized water. The method has the advantages of environmentally-friendliness, combination of disinfection and cleaning, synchronous completion of stain removal and disinfection, safety, unstimulating property, and resource conservation.

The invention discloses a method for producing adipic acid, hexamethylenediamine hydrochloride and polyhexamethylene (di)guanidine chloride from waste nylon-66 serving as a raw amerial through depolymerization, which is characterized by comprising the following steps of: depolymerizing the waste nylon-66 by using hydrochloric acid to obtain refined adipic acid and hexamethylenediamine hydrochloride; polymerizing the hexamethylenediamine hydrochloride and dicyandiamide (in a molar ratio of 1:1) at the temperature of between 170 and 190DEG C for 1 to 3 hours to obtain a white or pale yellow solid polyhexamethylene diguanidine chloride; and adding dicyandiamide and ammonium chloride powder in a molar ratio of 1:2 into a reactor, performing reaction at high temperature for 1 to 3 hours, slowly adding hexamethylenediamine hydrochloride powder, continuously reacting for 3 to 7 hours to obtain a white or pale yellow solid polyhexamethylene guanidine chloride. The method improves production efficiency, reduces production cost, and solves the problems of difficult separation of the product hexamethylenediamine due to depolymerization, low yield and poor benefit; and the technological process is environment-friendly, simple and convenient, and is suitable for industrial production.

The present invention relates to a manufacture method of micro-organism-inhibiting gel. The manufacture method comprises the following steps: 1) raw materials are weighed and the weighed raw materialsare cleaned and selected for a standby application; 2) 20 ml of ethanol is taken to dissolve 3 g of methyl 4-hydroxybenzoate to prepare a methyl 4-hydroxybenzoate solution for a standby application;3) radix sophorae flavescentis, cortex phellodendri, fructus cnidii, safflowers and mint are taken, water is added, and the materials are cooked twice to obtain an extractum for a standby application;4) 20 g of carbomer is taken, 100 g of purified water is added, and the carbomer is soaked for 24 hours until fully swollen to obtain a gel matrix for a standby application; 5) the methyl 4-hydroxybenzoate solution is mixed with the extractum, polyhexamethylene biguanide hydrochloride and glycerin are added, triethanolamine is added dropwise to adjust pH to 7, purified water is supplemented to atotal mass of 1,000 g, and stirring and mixing evenly are conducted for a standby application; and 6) sub-packaging, inspecting, packaging, and storing after qualified are conducted. Advantages are asfollows: the micro-organism-inhibiting gel with an average micro-organism-inhibiting rate of 50% or more against staphylococcus aureus, candida albicans and escherichia coli can be prepared, and themicro-organism-inhibiting gel has remarkable results in diseases of genital itching, waist and abdomen pains, abnormal leukorrhea, frequent urination, odynuria, etc.

The invention relates to a composition for killing microorganisms. The composition is utilized mainly for hygienic hand disinfection, surgical hand disinfection, skin and mucosa disinfection and killing of microorganisms on object surfaces. The composition adopts poly(hexamethylene biguanide) hydrochloride and ethanol as main active ingredients for sterilization and isopropanol as a combination sterilization synergist, wherein ethanol concentration is in a range of 238 to 467 g / L, poly(hexamethylene biguanide) hydrochloride concentration is in a range of 0.01 to 15 g / L and isopropanol concentration is in a range of 9 to 54 g / L. According to needs, the composition can be added with a humectant, a stabilizer, a thickener and the like to be prepared into different forms of preparations. The composition has the advantages of good sterilization effects, fast onset, no need of washing, high stability, reduction of stimulation effects of products on skin, and favorable functions of moisturizing and protecting skin.

The present invention provides a method for controlling allergens by applying an anti-allergenic effective amount of one or more anti-allergenic agents selected from hyperbranched polymers, amines (including tertiary amines), hops extracts, anti-allergenic iodo derivatives, quaternary ammonium compounds, hydantoins and hydantoin blends, polyhexamethylenebiguanidine hydrochloride, natural oils, anti-allergenic natural acids, sodium carbonate, chelating agents, cyclic ketone acids (e.g., dehydroacetic acid (DHA) and salts thereof (including sodium dehydroacetate and the monohydrate thereof)), anti-allergenic surfactants, organic phosphates, hydrogen peroxide, butylene glycol, phenoxyethanol, sodium salicylate, and mixtures thereof, to the allergens or a substrate on which they are located. These anti-allergenic agents are particularly effective at controlling household allergens, such as dust mites.

Disclosed is a cleaning agent containing a 0.0001-0.01% by weight aqueous solution or aqueous dispersion (A) of a linear poly(meth)acrylamide having an average molecular weight determined from limiting viscosity of not less than 5 106, a polyhexamethylene biguanide hydrochloride (B) represented by the formula (1) below, and at least one compound (C) selected from the group consisting of propylene glycol, dipropylene glycol, tripropylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, ethylene glycol, an ether of propylene glycol and an alcohol having 1-3 carbon atoms, an ester of one of them and a fatty acid having 1-3 carbon atoms, glycine and taurine. Formula (1): [-(CH2)m-NH-C(NH)-NH-C(NH)-NH-(CH2)n-]pHCl. In the formula, m and n respectively represent an integer of 2-5, and p represents an integer of 5-16.

The invention relates to a bacteriostatic isolation coating film-forming liquid for a medical inspection platform and a preparation method thereof. The film-forming liquid containing solid micro-particles comprises a silica sol component loaded with nano silver-titanium dioxide, a nano silver-doped organic-modified mesoporous silica antibacterial composite microsphere component, a composite organic resin component, polyhexamethylene biguanide hydrochloride or phosphate, and an other auxiliary agent component. The bacteriostatic isolation coating film-forming liquid can be used for the surfacefilm-forming isolation use of the hospital inspection platform such as various working or operating tables, appliance storage-taking brackets or working cabinets, and has excellent disinfection bacteriostatic function and hydrophobic and easy-cleaning function.

The invention relates to a bactericidal and preservative agent combination for the repair-regeneration of microbial pollution products, which comprises the following active ingredients: a preservative agent A, a preservative agent B, a bactericide, solvents, additives and water, wherein the preservative agent A is formed by bronopol, the preservative agent B is formed by parachlorometaxylenol PCMX and a phenoxyethanol mixture, and the bactericide is formed by 2,2-dibromo-3-nitrilo-propionamide DBNPA or polyhexamethylene biguanidine hydrochloride PHMB. Through one-time addition, the bactericidal and preservative agent combination disclosed by the invention has strong synergistic, preservative and bactericidal effects, and can concurrently have the functions of bactericidal repair and corrosion and mildew prevention in the period of re-storage, thus most of industrial water-based products metamorphosed by microbial pollution are reused. The bactericidal and preservative agent combination disclosed by the invention has the advantages of reasonable formula, advanced process, high cost performance, low toxicity, good operational feasibility, bactericidal and preservative effect, and the like, and is verified through a lot of industrial practices.

The invention discloses an aerial fog disinfectant and a preparation method thereof. The preparation method mainly comprises the steps of preparing poly(hexamethylene biguanide) hydrochloride as a disinfection factor, dimethyl didecyl ammonium sulfide, propylene glycol as a solvent, ethanol, and the like into liquid disinfectant through a certain process and sealing the liquid disinfectant in a pressure-proof vessel and then filling a certain amount of propellant to ensure that the disinfectant is dispersed on the surface of an object in the form of fog. The invention is mainly used for spraying and disinfecting surfaces of hands, skin and ordinary objects to achieve convenient and rapid disinfection effect.

The invention discloses a moisturizing and skin-moistening wash-free gel disinfectant containing hyaluronic acid. The gel disinfectant comprises the following components in percentage by weight: 0.5%-1% of carbomer, 3%-5% of glycerol, 2%-3% of propylene glycol, 1%-5% of an aloe extract, 30%-50% of neutral alcohol, 1%-5% of hyaluronic acid, 0.1%-0.2% of polyhexamethylene biguanidine hydrochloride,and the balance of deionized water. According to the moisturizing and skin-moistening wash-free gel disinfectant containing hyaluronic acid, polyhexamethylene biguanidine hydrochloride and neutral alcohol are used at the same time, so that the disinfectant has an effective sterilization and disinfection effect, the dosage of the neutral alcohol can be reduced, and the harm to the human skin is reduced. Glycerol, the aloe extract and hyaluronic acid can be used for moisturizing the human skin, so that the problems of water shortage, decrustation, itchiness and the like of the human skin due tofrequent use of disinfectants are avoided. In addition, the aloe extract has a strong moisturizing function, and also has the effects of sterilization, bacteriostasis, anti-inflammation and detoxification.

The invention discloses a guanidyl composite disinfection and cleaning hand sanitizer and a preparation method for the same. The hand sanitizer comprises the following chemical compositions: polyhexamethylene biguanidine hydrochloride, polyoxyethylene octylphenol ether, fatty alcohol-polyoxyethylene ether, polyethylene glycol, propylene glycol and deionized water. The preparation method for the hand sanitizer comprises the following steps of adding deionized water in a container, heating, and then adding a polyhexamethylene biguanidine hydrochloride aqueous solution to obtain a pre-solution; sequentially adding polyoxyethylene octylphenol ether, fatty alcohol-polyoxyethylene ether, polyethylene glycol and propylene glycol in the pre-solution to obtain a basic solution; adding all of the residual deionized water in the basic solution to prepare the disinfection and cleaning hand sanitizer. The hand sanitizer disclosed by the invention is high in sterilization effect, high in safety and more stable in properties, and has a skin care function; the product is a colorless clear liquid in character, and is not changed in color in long-time storage.

The invention relates to a disinfectant, in particular to a multifunctional universal disinfectant, which belongs to the technical field of medical supplies for external use. The disinfectant providedby the invention is prepared from the following components in parts by weight: 4 to 6 parts of polyhexamethylene biguanidine hydrochloride, 2 to 4 parts of enzyme, 1 to 3 parts of plant extract, 1 to2 parts of food-grade citric acid monohydrate, 5 to 8 parts of auxiliary bactericide, and 900 to 1200 parts of purified water. According to the disinfectant provided by the invention, by adopting a compound manner of the polyhexamethylene biguanidine hydrochloride, the enzyme and the plant extract, the fundamental form of sterilization and disinfection is changed, and the formula provided by theinvention is a physical sterilization principle which is mild without irritation and is different from a chemical sterilization principle of traditional disinfectants such as iodine and ethyl alcoholcapable of sterilizing but producing irritation at the same time.

The invention relates to a gynecological collagen lotion and a preparation method thereof. The gynecological collagen lotion is prepared from 0.5-10% of glycerinum, 0.5-10% of propylene glycol, 0.5-10% of cocamidopropyl betaine, 0.01-0.2% of menthol, 0.01-0.1% of collagen, 0.01-2.0% of fructo-oligosaccharide, 0.1-2% of hydroxyethyl cellulose, 0.01-0.5% of polyhexamethylene biguanide hydrochloride,0.01-0.3% of ethylparaben, 1-5% of plant extracts, 0.01-2% of lactobacillus leavening and the balance of purified water till 100%. Due to adoption of the cocamidopropyl betaine and the plant extractsas main raw materials, and by virtue of synergetic functions of the raw materials and auxiliary materials, the gynecological collagen lotion which is good in treatment effect and free of irritation to vulvae can be prepared, and the product has remarkable antibacterial effects on escherichia coli, staphylococcus aureus, candida albicans and the like, and is capable of preventing propagation of harmful bacteria and maintaining cleanliness and health of the vulvae.

The invention relates to a durable fabric mold-proof and antistatic finishing agent. The durable fabric mold-proof and antistatic finishing agent is prepared from the following raw materials: polyhexamethylene biguanide hydrochloride, 1-hydroxy-2-pyridine sulfur copper, tetraisopropyl titanic acid, sulfated glycine betaine, polyvinyl alcohol, citric acid, isothiazolinone, white carbon black, SCJ-2000, bentonite, cellulose acetate butyrate and sodium polyacrylate. A fabric treated by the finishing agent has antibacterial, mold-proof and antistatic effects, mothproof and odor-removing functions, samll use amount and low cost.

The invention discloses a vagina cleaning care lotion and a preparation method thereof. The vagina cleaning care lotion for external use is prepared from raw materials as follows: radix sophorae flavescentis, phellodendron bark, fructus cnidii, borneol, tea tree oil, rosemary, alum, hydrolyzed collagen, polyhexamethylene biguanidine hydrochloride, chlorhexidine acetate and water; after radix sophorae flavescentis, fructus cnidii and phellodendron bark are boiled with water in proportion and extracted, an extracting solution is concentrated to the relative density of 1.01-1.04, chlorhexidine acetate, borneol, tea tree oil, rosemary, alum, hydrolyzed collagen, polyhexamethylene biguanidine hydrochloride and water are added, and the anti-germ care lotion suitable for vagina cleaning of both men and women is obtained through mixing, filling and packaging. The lotion has the efficacy of clearing heat, removing toxicity, clearing dampness and killing parasites to relieve itching, inhibits growth of harmful germs of the vagina, clears away peculiar smell and effectively relieves female vulvitis, vaginal itching and other symptoms. The formula is reasonable, and the vagina cleaning care lotion doesn't have toxic and side effects or allergic reaction and has good treatment and prevention functions on gynecological diseases such as germ infection of the vulva, the vagina and the urethra and the like.

The invention relates to the technical field of wet tissue and provides multifunctional wet tissue and a preparation method therefor. The multifunctional wet tissue comprises a substrate and a wet-tissue compounded solution infiltrated into the substrate, wherein the wet-tissue compounded solution comprises the following ingredients in parts by weight: 0.01-0.1 part of aloe vera extract, 0.1-0.5 part of cucumber juice, 1-5 parts of herba menthae essential oil, 0.2-0.4 part of pine needle oil, 0.3-0.6 part of orange peel essential oil, 1.5-3 parts of borneol, 0.4-0.8 part of polyhexamethylene biguanide hydrochloride, 1.2-3.6 parts of propylene glycol, 1.5-3 parts of lauryl-alcohol polyoxyethylene ether, 0.2-0.4 part of solubilizer and 85-95 parts of deionized water. The problem in the priorart that the wet tissue is relatively single in function is solved, and the prepared wet tissue integrates the effects of cleaning, moisturizing, sterilizing and refreshing.

The invention provides a topical pharmaceutical composition for preventing and treating bacterial vaginosis. The pharmaceutical composition comprises the following traditional Chinese medicine materials in parts by mass: 25-35 parts of curcuma zedoary, 20-30 parts of fructus cnidii, 45-55 parts of radix sophorae flavescentis, 5-15 parts of alumen, 10-20 parts of fructus kochiae, 10-20 parts of rhizoma atractylodis, 90-110 parts of flos rosae rugosae, 10-14 parts of golden cypress, 8-10 parts of cortex dictamni, 4-6 parts of borneol, 8-12 parts of aloe vera gel, 1-3 parts of vitamin E, 0.1-0.2 part of hyaluronic acid, 0.2-0.4 part of polyhexamethylene biguanide hydrochloride, and 1-2 parts of lactic acid milk. The pharmaceutical composition provided by the invention has obvious inhibition effect on bacteria, also has obvious inhibition effect on candida albicans, but has no inhibition effect on lactobacillus. The pharmaceutical composition has obvious treatment effect on female bacterial vaginosis after clinical use, and has no stimulation on vagina.

The invention provides a disinfecting washing agent. The disinfecting washing agent is prepared from, by weight, 10-15 parts of an anionic surfactant or a nonionic surfactant, 1-3 parts of sodium alginate, 3-5 parts of lignosulfonate, 5-8 parts of polyhexamethylene biguanidine hydrochloride, 5-10 parts of divaricate saposhnikovia extract, 1-3 parts of an active enzyme and 40-50 parts of deionized water. The disinfecting washing agent has the dual functions of stain removal and disinfection, and is mild, free of simulation or toxin and friendly to the environment.

The invention discloses antibacterial coating for the surface layer of medical equipment and a preparation method of the antibacterial coating. The antibacterial coating comprises, by weight, 28-35 parts of epoxy resin, 20-30 parts of organic siloxane resin, 8-16 parts of ash-calcium powder, 6-12 parts of calcium silicon, 4-8 parts of talcum powder, 3-6 parts of mica powder, 4-7 parts of castor oil, 3-8 parts of chitosan, 5-10 parts of zeolite powder, 3-6 parts of zirconium phosphate, 2.5-4.3 parts of nano silver, 3-5 parts of nano titanium dioxide, 4-7 parts of nano zinc oxide, 3-6 parts of activated carbon, 2-5 parts of bamboo carbon powder, 2.3-3.8 parts of polyhexamethylene biguanidine hydrochloride, 3.5-5.2 parts of titanate coupling agent, 1.5-2.6 parts of dispersing agent, 2.4-3.6 parts of preservatives, 1.8-3.4 parts of leveling agent, 0.8-2.2 parts of defoaming agent and 15-23 parts of water. The antibacterial coating is good in adhesiveness, less prone to falling and excellent in antibacterial effect.

The invention discloses a fabric mildew-resistant antiseptic and a preparation and an application method thereof. The fabric mildew-resistant antiseptic comprises the following raw materials by weightpercentage: 10-30% of a mildew inhibitor, 15-30% of an antiseptic, 1-10% of an emulsifier, 1-15% of a cross-linking agent, and 20-65% of a solvent; wherein the mildew inhibitor is selected from at least one of tebuconazole, didecyl dimethyl ammonium chloride, dioctadecyl dimethyl ammonium chloride, pyrithione urea, and TCMTB; the antiseptic is selected from at least one of chlorothalonil, sodiumpyrithione, beta-thujaplicin, and polyhexamethyl biguanide. The fabric mildew-resistant antiseptic has good mildew-resistant and anti-microbial effects, has no influence on performance of fabric and no generation of harmful substances, and has the advantages of environmental protection, good safety, and no stimulation on skin; and the method has the advantages of simple production technology, short production period, less energy consumption, and low cost, and is in favor of popularization in middle and small-sized enterprises.

The invention discloses a deodorizing bacteriostat cat litter and a manufacturing method thereof, and belongs to the technical field of pet supplies. The cat litter is made by raw materials of modified zeolite particles, silica gel, activated carbon, polycyclohexane biguanide hydrochloride, lemon essence, and a binding material. A NaCl solution is used to modify the zeolite particles, and adsorption exchange capacity of zeolite on ammonia nitrogen is improved, and deodorizing capability of the zeolite on pet cat litter is enhanced. The cat litter is also added with the polycyclohexane biguanide hydrochloride, that is, PHMB, which has a bactericidal effect. The polycyclohexane biguanide hydrochloride cooperated with silica gel can effectively restrain various bacteria generated in an excretion process of a pet cat, so as to provide a healthy living environment for the pet cat. The cat litter does not have dust in use, the cat litter is deodorant and bacteriostatic, and emits fragrance.The cat litter is simple in manufacturing process, and is suitable for popularization and application.

The invention discloses a disinfecting and sterilizing cleanser for computers and a preparation method thereof. The cleanser can quickly clean the computers and kill bacteria and microbes on the computer surface. The cleanser is composed of polyhexamethylene bis-guanidine hydrochloride, polyhexamethylene mono-guanidine hydrochloride, octyl phenol polyethenoxy ether, coconut diethanolamide and deionized water. The method comprises the following steps: adding part of deionized water into a container, heating, adding a polyhexamethylene mono-guanidine hydrochloride solid and a polyhexamethylene bis-guanidine hydrochloride water solution, and sufficiently stirring; sequentially adding the octyl phenol polyethenoxy ether and coconut diethanolamide, and stirring uniformly; adding the rest of deionized water, and mixing and stirring to obtain the disinfecting and sterilizing cleanser for computers. The cleanser has efficient cleaning power, can forcefully remove dirt and clear away fingerprints, oil stains and the like without water washing, is not corrosive, can keep the digital product clean and bright, and can generate a protective layer on the surface of the digital product after use to prevent dust from being adsorbed.

The invention relates to the field of glass protective liquid, in particular to an anti-fog spray and a preparation method thereof. The anti-fog spray is prepared from the following components in percentage by mass: 0.1-10% of an antifogging agent, 0.1-10% of an antibacterial agent, 0.1-10% of a stabilizer, 0.5-10% of an anti-static agent, and 80-98% of a solvent, wherein the antifogging agent comprises one or more of fatty alcohol-polyoxyethylene ether, sodium fatty alcohol polyoxyethylene ether sulfate, octaphenyl polyoxyethyiene, and cocoanutfatty acid N,N-diethanol a; the antibacterial agent comprises one or more of chlorothalonil, beta-thu and polyhexamethylene biguanidine hydrochloride; and the anti-static agent comprises one of N-hexadecylpyridine nitrate and sodium alkyl benzene sulfonate. By adopting a macromolecular surfactant to be better combined with silicon dioxide of glass, good durability and stability are achieved; through adding of the anti-static agent, charges on the glass surface can be eliminated, so that dust is not prone to adhering to the glass surface, and safe and stable performance is achieved; and through adding of the antibacterial agent, any corrosioneffect on various metal is avoided, the antibacterial and anti-mold effects are can be achieved, the poisonless and harmless effects are achieved, and use is wide.

The invention discloses a chitosan quaternary ammonium salt multi-sterilization-system contact lens care solution, which is prepared from sterilization agents, moisture preservation agents, cleaning agents, buffer agents, osmotic pressure regulating agents and chelating agents, wherein the sterilization agents comprise chitosan quaternary ammonium salt and one or a mixture of several kinds of materials selected from poly-quaternary ammonium salt, polyhexamethylene biguanidine hydrochloride, polyaminopropyl biguanide and myristoyl propyl dimethylamine. The chitosan quaternary ammonium salt multi-sterilization-system contact lens care solution has the advantages that the content of each sterilization agent can be reduced through a multi-sterilization-agent system; the cooperated and matching effect between the sterilization agents can be sufficiently utilized; good sterilization performance and biocompatibility can be ensured; the duplex effects of sterilization and moisture preservation are achieved.