Bacteriostatic isolation coating composition for medical inspection platform and preparation method thereof
An isolation coating and platform technology, applied in coatings, biocide-containing paints, antifouling/underwater coatings, etc., can solve the problems of poor thermal stability and mechanical properties, unsuitable for surface treatment, etc., and achieve excellent mechanical properties Performance, the effect of excellent antibacterial effect
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preparation example 1
[0076] Preparation of silica sol loaded with nano silver-titanium dioxide
[0077] 1) Weigh 17.0 mg of silver nitrate, add 100 ml of deionized water to dissolve and prepare a 1 mmol / L silver nitrate solution, and store the prepared silver nitrate solution in a brown volumetric flask away from light. Take 60ml of the above-mentioned silver nitrate solution and place it in a conical reaction flask with a stirring bar, add 9ml of 40mM sodium citrate solution as a stabilizer, stir for 5min, then add dropwise 6ml of 10mM sodium borohydride under rapid stirring and dark conditions The solution was stirred while adding dropwise, and magnetic stirring was continued for 3 h after the dropwise addition was completed to obtain a clear nano-silver solution.
[0078] 2) Take 50mL of the above nano-silver solution, slowly drop it into 600g of 10% silica sol solution (silicon dioxide dispersion solution), avoid light, and ultrasonically disperse evenly.
[0079] 3) Weigh 1.2 g of nano-titan...
preparation example 2
[0081] Preparation of Organically Modified Mesoporous Silica-Nanosilver Antibacterial Composite Microspheres
[0082] 1) Take 10g of mesoporous silica powder and 3g of polyvinylpyrrolidone organic modifier, disperse them in 100ml of distilled water respectively, heat the two solutions to 60°C for mixing and stirring, add 50ml of DMF solvent and 0.5g of triethoxy After the silane coupling agent was stirred for 2 hours, it was filtered by a vacuum pump, the filter cake was washed with deionized water, dried and ground to a size of no more than 80 nm, and organically modified silica microspheres were obtained.
[0083] 2) In a reaction device equipped with stirring and a thermometer, mix 200ml of 50mg / ml organically modified silica microsphere aqueous dispersion with 10ml of 10mM AgNO 3 The solutions were mixed, and stirred at room temperature for 2 hours in the dark, and then 5ml of 20mM sodium borohydride solution was added dropwise under stirring conditions. After the dropwise...
preparation example 3
[0085] Preparation of Polyvinyl Alcohol Dispersion of Antibacterial Composite Microspheres
[0086] At 60°C, the antibacterial composite microspheres obtained in Preparation Example 2 were added to a certain amount of 3wt% mass fraction of polyvinyl alcohol transparent solution, magnetically stirred for 60min, then ultrasonically oscillated for dispersal for 15min, and then magnetically stirred for 60min again after ultrasonically oscillated. Obtain the antimicrobial microparticle dispersion, wherein the mass percent of the antibacterial microsphere in the antibacterial composite microsphere dispersion is 12%.
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