37 results about "Biochemical testing" patented technology

The invention provides an apparatus and methodology to carry out biochemical testing on a centrifugal platform using flow splitting technique. In conventional biochemical testing, reagents need to be loaded individually into each reservoir. By using the flow splitting technique in this invention, one reagent only need to be loaded once, then, it can be evenly distributed into each reaction chambers in single or multiple layers format. The invention greatly reduces the required manpower when large numbers of assays are integrated on one platform. Because of the invention, many medical examinations can be performed efficiently, thus reduce the waste of manpower, time and cost.

This invention provides methods and kits for improved diagnosis of medically relevant conditions by solution based biochemical testing procedures performed in solutions of test samples. The invention provides a method to substitute the cell based morphological information contained within the cytological and / or histological data of the test sample by molecular information obtainable from the solution, wherein the original test sample is dissolved and thus enables for accurate and reproducible assessment of medically relevant diagnosis from dissolved test samples. The method according to the invention comprises the steps of determining the levels of one or more disease markers associated with the condition to be diagnosed, determining the level of one or more normalization markers suitable to substitute the information related to morphological aspects of the sample, comparing and / or combining the data of the disease and normalization markers, and assessing diagnosis of a medically relevant condition.

The invention provides a micro-fluidic chip for chemiluminescence detection, and a using method and a reagent cleaning method thereof, and belongs to the field of biochemical testing devices. The micro-fluidic chip comprises a substrate and a cover plate which form a sealing environment and are used for a micro-fluid to flow, the substrate is covered with the cover plate, and the substrate comprises: a sample adding hole and a diluted solution adding hole at the first layer; a sample quantification groove, a sample overflow groove, a diluted solution quantification groove and a dilution overflow groove at the second layer; an incubation groove at the third layer, solution storage grooves at the fourth layer, a detection groove at the fifth layer and a waste liquid groove at the sixth layer, wherein the sample quantification groove is communicated with the incubation groove, the diluted solution quantification groove is communicated with the incubation groove, the incubation groove is communicated with the detection groove, and the detection groove is communicated with the waste liquid groove through a hydrophobic flow channel. The separation, mixing and detection of a liquid is realized without repeatedly adding a sample, and the whole process is automatically completed, so the efficiency is increased, and the cost is realized; and the cleaning of a reaction reagent is realized, so the working efficiency is increased.

The invention discloses a diabetes predicting model construction method based on electronic medical record data mining. The method comprises the steps of performing electronic medical record data cleaning, constructing a predicting model, performing data integration on the electronic medical record data which are introduced from each server through a unique medical case number, wherein the data comprise basic information, diagnosis data, saccharification testing data and biochemical testing data, and integrating the basic information, the diagnosis information and the like for obtaining a whole sample. Data cleaning is performed for eliminating abnormal data, repeated data and existing error data. The cleaned data are stored in a database. Classification prediction is performed on the cleaned diabetes data. Through a result, the classification precision and the model evaluation index of the improved BP neural network model are higher than that of other algorithm models. The method hasadvantages of improving detection rate of undiagnosed diabetic nephropathy in the population, improving diabetic nephropathy preventing effect and saving a large amount of sanitation resource.

The invention relates to an integrated grating micro-cantilever biochemical sensor and a chip manufacturing method, comprising metal grating and an electrode arranged at the surface of a glass sheet; an insulating layer is covered onto the electrode and the grating, and the glass sheet is provided with a micro-cantilever structure and a specific adsorption layer on the upper surface of the micro-cantilever, and a certain clearance is arranged between the micro-cantilever and the grating, a photoelectric detective circuit is connected with the electrode. The characteristic that the light intensity of the diffraction light spot changes along with the sensitivity of the distance from the grating surface to the lower reflecting surface of the micro-cantilever is utilized to realize the biochemical testing of high sensitivity. The MEMS technology and the mature laser diode, photodetector are utilized, and the mass production can be conducted, and the invention is easy to popularize and apply.

The invention discloses a kit based on single particle diameter for simultaneously detecting beta2-microglobulin in serum and urine specimen. The kit comprises a reagent R1, a reagent R2, a calibration product and a quality control product, wherein the reagent R2 consists of a streptavidin marked latex-biotin marked rabbit anti-human beta2-microglobulin polyclonal antibody and reagent R2 buffer liquid. The kit has the advantages that the reagent sensitivity is improved; the measuring range is greatly increased; the beta2-microglobulin in the blood and urine specimen can be simultaneously detected; meanwhile, most biochemical testing equipment in the market can be compatible; the kit can directly enter the market.

A series of unique biochemical tests are combined to enable unskilled law enforcement and private investigation personnel to rapidly perform sex crime investigations on skin swipes and body fluid residues deposited on specific articles of clothing. The invention also allows spouses to privately identify and monitor infidelity activities of their mate through the application of this test kit to personal clothing and other areas where body fluids may be found.

Present invention belongs to no radiation detective instrument which uses organism enzyme technology foundation, a biosensor adopting electrochemical method testing glucose, uric acid and cholesterol parametric in blood. It features adopting screen print technology printing silver, carbon syrup and insulating paint to substrate material layer, finally over printing self-adhesive to form three electrochemical reaction pools. It can combine relevant detection instrument time-sharing and stepped taking the measurements blood sugar, uric acid and cholesterol three physiological parameters, to satisfy medical clinical detective variety requirement and domestic use.

The invention provides an apparatus and methodology to carry out biochemical testing on a centrifugal platform using flow splitting technique. In conventional biochemical testing, reagents need to be loaded individually into each reservoir. By using the flow splitting technique in this invention, one reagent only need to be loaded once, then, it can be evenly distributed into each reaction chambers in single or multiple layers format. The invention greatly reduces the required manpower when large numbers of assays are integrated on one platform. Because of the invention, many medical examinations can be performed efficiently, thus reduce the waste of manpower, time and cost.

A microfluidic apparatus and methods for fabrication with a fluidic layer and a pattern layer of spots of concentrated reagents that are disposed in wells of a fluidic layer when the two layers are bonded together. Reagents are stored on the chip prior to use. Because reagents are confined to specific wells, contamination of the channels and other microfluidic structures of the fluidic layer are avoided. The fluidic layer also has a system of vacuum channels and at least one vacuum void to store vacuum potential for controlled micro-fluidic pumping. The top and bottom surfaces of the bonded layers are sealed. The chip can be used for point of care diagnostic assays such as quantitative testing, digital nucleic acid amplification, and biochemical testing such as immunoassays and chemistry testing.

A portable biochemical testing apparatus and operating method thereof are disclosed. The portable biochemical testing apparatus includes a light source module, a sample module, a photoconductive material layer, a touch module, and a control module. At least one sample is disposed in the sample module. The photoconductive material layer is disposed between the sample module and the light source module. The touch module generates a driving signal according to a touch action of the user to drive the light source module to emit a light. When the light is emitted to the photoconductive material layer, the photoconductive material layer will generate a photoelectric driving effect. The at least one sample is affected by the photoelectric driving effect and generates a change corresponding to the touch action.

The invention discloses application of citral and / or a citral-containing plant extract in preparation of a plant resistance inducer. The application range of the plant resistance inducer comprises induction of plant disease resistance, induction of plant stress resistance or promotion of plant growth. The plant disease resistance inducing activity, plant stress resistance inducing activity and plant growth promoting activity of the citral and the citral-containing plant essential oil or extract are determined by biological activity determination, physiological and biochemical testing and other methods; a pesticide preparation, an auxiliary agent and a biostimulant which take citral and citral-containing plant essential oil or extract as active ingredients are prepared, and are applied in the field.

Provided is a biochemical test chip including an insulating substrate, an electrode unit, a first insulating septum, a reactive layer, a second insulating septum, and a color-changing layer. The electrode unit is located on the insulating substrate. The first insulating septum is located on the electrode unit and has an opening. The opening exposes a portion of the electrode unit. The reactive layer is located in the opening. The second insulating septum is located on the first insulating septum. The color-changing layer is located at least on a region outside the reactive layer. The color of the color-changing layer is changed with a change in an environmental factor.

The invention discloses a urine detection system. The urine detection system comprises a controller, a dry chemical urine test unit, a science urine test unit, a urine formed element test unit and a biochemical urine test unit; and the dry chemical urine test unit, the science urine test unit, the urine formed element test unit and the biochemical urine test unit are respectively connected with the controller electrically. A method specifically comprises the steps of: A, obtaining test items of a urine sample; B, performing urine sample detection; C, performing detection result analysis; and F, providing a urine sample detection result. According to the urine sample analysis system and method in the invention, the dry chemical urine test unit, the science urine test unit, the urine formedelement test unit and the biochemical urine test unit are integrated in a body; the limitation of the existing urine sample analysis system is broken through; therefore, urine detection is relativelyconvenient; and a detection result is relatively accurate.

The invention discloses a screening method for strains of lactobacilli generating GABA in chickpea milk. Steps of the screening method are as follows: firstly, pretreatment of chickpea milk samples; secondly, separation of amino acids by means of paper chromatography; thirdly, initial judgment of the lactobacilli generating the GABA; fourthly, secondary judgment of the lactobacilli generating theGABA; fifthly, morphological identification of the lactobacilli generating the GABA; sixthly, physiological and biochemical testing for the lactobacilli generating GABA; and seventhly, identificationof the strains of lactobacilli generating the GABA through a 16SrDNA sequence. According to the screening method, researchers divide No. 2 solutions into two parts in the process of detecting the No.2 mixed solutions through a high performance liquid chromatograph, firstly detect one part of the solutions and record data, and then detect the other part of mixed solutions again after the mixed solutions are statically placed for 20-24 hours and record data to compare the data of the two detections, quantity of the GABA in the solutions after static placement is significantly increased, so asto determine the existence of the strains of lactobacilli generating the GABA in the chickpea milk. Therefore, experimental errors are reduced, and the screening method lays a foundation for developing GABA-rich functional food.

A biochemical nutrient for relieving fatigue, building up body, improving immunity and preventing cardiovascular and cerebrovascular diseases is prepared from ostric meat through granulating, mixing with water, pancreatin and dispase, biochemical reacting, filtering to remove dregs, heating to 80 degc, holding the temp for 30 min for deactivating enzyme, concentrating and sterilizing.

The present disclosure provides a biochemical test chip, including an electrode unit and a protective layer. The protective layer is electrically connected to the electrode unit. The protective layer is configured to oxidize the electrode unit after the electrode unit receives an electron or reduce the electrode unit after the electrode unit loses an electron. There is a potential difference (Ecell0) between the protecting layer and the electrode unit.

The invention is a toilet seat for convenient urine testing, which comprises a seat body and a swing rod. A lead screw is arranged inside the swing rod along the length direction, a slider is installed on the lead screw, and a mobile test paper tray is connected above the slider. A test paper tray is arranged above the tray, a test paper bin is arranged at the end of the swing rod, a darkroom is arranged beside the test paper bin, a camera detection mechanism is installed in the dark chamber, and a discard opening is arranged at the front end of the swing rod housing. The convenient urine test provided by the present invention The toilet seat sets the urine collection and detection device on the seat, and completes the urine collection, urine soaking and paper discarding at the front end of the swing rod, which simplifies the structure of the urine testing system and reduces the cost; using the urine testing toilet seat can Biochemical testing of urine is carried out at every convenience, so that people can know their own health conditions at any time, and carry out prevention and treatment according to the test results. It is truly prevention-oriented, self-defense and autonomy, which can effectively improve people's health. levels to prevent disease.

The invention discloses a hemarthria compressa ISAP (Intron Sequence Amplified Polymorphism) fingerprint spectrum establishing method and applications of the method. According to the method, different hemarthria compressa germplasm DNA (Desoxvribose Nucleic Acid) fingerprint spectra are established by virtue of an ISAP molecular marking technology, which is conductive to rapid and accurate identification of clonal hemarthria compressa; compared with the conventional morphology testing and biochemical testing, the method is free from effects of growing environment and seasons, more reliable in result, time-saving and labor-saving; the method has the characteristics of being simple to operate, achieving visual practicability and the like, and can promote the wide application of the ISAP molecular marking technology in accurate, rapid and simple variety identification; besides, the method can be used for identifying the genetic variation on the clonal germplasm of hemarthria compressa, thereby meeting the requirements on early screening of variation on the clonal germplasm of hemarthria compressa and breeding of new varieties.

Provided is a compound. According to the embodiment of the invention, the invention relates to the compound represented by the formula (I), or stereoisomers, tautomers, nitrogen oxides, solvates, metabolites, pharmaceutically acceptable salts or prodrugs of the compound represented by the formula (I). The compound can effectively obtain two or three or more ubiquitin chains and ubiquitin modifiedsubstrates; moreover, the compound can be used for modifying polypeptide or protein side chains with affinity labels, fluorescent groups, PEG or fatty hydrocarbons and the like; and the compound can play an important role in design of polypeptide drugs, biochemical testing, functional optimization and the like.

Provided is a compound. According to the embodiment of the invention, the invention relates to the compound represented by the formula (I), or stereoisomers, tautomers, nitrogen oxides, solvates, metabolites, pharmaceutically acceptable salts or prodrugs of the compound represented by the formula (I). The compound can effectively obtain two or three or more ubiquitin chains and ubiquitin modifiedsubstrates; moreover, the compound can be used for modifying polypeptide or protein side chains with affinity labels, fluorescent groups, PEG or fatty hydrocarbons and the like; and the compound can play an important role in design of polypeptide drugs, biochemical testing, functional optimization and the like.

The invention discloses a hemarthria compressa ISAP (Intron Sequence Amplified Polymorphism) fingerprint spectrum establishing method and applications of the method. According to the method, different hemarthria compressa germplasm DNA (Desoxvribose Nucleic Acid) fingerprint spectra are established by virtue of an ISAP molecular marking technology, which is conductive to rapid and accurate identification of clonal hemarthria compressa; compared with the conventional morphology testing and biochemical testing, the method is free from effects of growing environment and seasons, more reliable in result, time-saving and labor-saving; the method has the characteristics of being simple to operate, achieving visual practicability and the like, and can promote the wide application of the ISAP molecular marking technology in accurate, rapid and simple variety identification; besides, the method can be used for identifying the genetic variation on the clonal germplasm of hemarthria compressa, thereby meeting the requirements on early screening of variation on the clonal germplasm of hemarthria compressa and breeding of new varieties.

The invention discloses an edible beef meat quality detection device. An edible beef meat quality detection device comprises a working panel, a moving system located above the working panel, and a cutting system, an optical detection system and a gas detection system sequentially arranged on the working panel. , fiber detection system; the device of the present invention does not need to use biochemical testing methods to achieve the detection effect of meat quality, and mainly adopts optical detection, odor detection, occlusion detection and statistical detection, which greatly shortens the test period and greatly reduces the test cost. Conditions are provided for the popularization of the equipment; the device of the present invention consumes less in meat quality detection of whole cattle, and can perform partial recovery, so that the loss rate of raw materials is greatly reduced.

A biochemical reaction device and a biochemical testing system relate to the technical field of biochemical testing, the biochemical reaction device comprises a first shell, a second shell and a pressing assembly, the first shell is internally provided with an accommodating cavity, the accommodating cavity is internally provided with a partition assembly to divide the accommodating cavity into a first sub-cavity and a second sub-cavity, the first sub-cavity is used for storing a sample, the second shell is contained in the second sub-cavity, a containing cavity is formed in the second shell, the containing cavity is used for storing reagents, a transportation assembly is arranged on the second shell, one end of the transportation assembly extends into the second shell to be communicated with the containing cavity, and the other end of the transportation assembly extends in the direction close to the separation assembly; one end of the pressing assembly extends into the second sub-cavity to abut against the second shell, and the other end of the pressing assembly is pressed to push the second shell to move relative to the first shell so as to drive the other end of the conveying assembly to penetrate through the partition assembly to communicate with the first sub-cavity; and the sample in the first sub-chamber enters the accommodating cavity through the transportation assembly and reacts with the reagent in the accommodating cavity.

The invention provides a seminal plasma composite quality control product, which is a freeze-dried powder made by mixing a quality control product preservation solution and a seminal plasma original solution; the quality control product preservation solution contains 0.47% to 0.67% sugar and salt. An aqueous solution of 0.07 to 0.17% of semen and 0.63 to 0.83% of enzyme stabilizer; the seminal plasma solution is the seminal plasma obtained by direct centrifugation of completely liquefied fresh human semen; the quality control product preservation solution is mixed with the seminal plasma solution The volume ratio is 1:100~100:1. The present invention uses a unique quality control product preservation solution, mixes it with the seminal plasma at an appropriate volume ratio and then freeze-dries it. This can make various biochemical indicators in the seminal plasma more stable, thereby effectively avoiding the in vitro storage of substances in the semen. It has the disadvantages of being very unstable and difficult to preserve. The prepared seminal plasma composite quality control product has stable performance and is easy to use, and can be used for quality control of seminal plasma biochemical testing projects.

A micro-testing lab for performing tests on biochemical and synthetic materials is provided. The testing lab includes a substrate forming the base material of the test lab; a poly silicon layer formed over the substrate; and a silicon dioxide layer deposited over the poly silicon layer, the poly silicon layer supporting a series of grooves, flow obstacles, and sensors for facilitating material flow, material separation, and material analysis. In a preferred embodiment, material is prepared in a preparation basin and introduced into a groove and propelled there through to at least one flow obstacle separating different molecules of the material to be tested and wherein upon separation, at least one sensor is utilized for performing analysis of the material. Also in preferred embodiments, the lab is field programmable and controllable through a control interface.

A testing device has a base and multiple strips connected to the base. Multiple antigens are placed on each strip. The testing device or strips may be affixed to a sheet under a shield. Fluid can be applied to the testing device or the strips. The testing device can be used for biochemical testing, such as line immunoassay (LIA) testing.

The invention discloses application of limonene in preparation of a plant resistance inducer. The application range of the plant resistance inducer comprises induction of plant disease resistance and induction of plant stress resistance. The plant disease resistance inducing activity and the plant stress resistance inducing activity of the limonene and the plant essential oil or extract containing the limonene are determined by using biological activity determination, physiological and biochemical testing and other methods, and a plant resistance inducer and a biostimulant which take the limonene as an active component are prepared and applied in fields.

The invention relates to an integrated grating micro-cantilever biochemical sensor and a chip manufacturing method, comprising metal grating and an electrode arranged at the surface of a glass sheet; an insulating layer is covered onto the electrode and the grating, and the glass sheet is provided with a micro-cantilever structure and a specific adsorption layer on the upper surface of the micro-cantilever, and a certain clearance is arranged between the micro-cantilever and the grating, a photoelectric detective circuit is connected with the electrode. The characteristic that the light intensity of the diffraction light spot changes along with the sensitivity of the distance from the grating surface to the lower reflecting surface of the micro-cantilever is utilized to realize the biochemical testing of high sensitivity. The MEMS technology and the mature laser diode, photodetector are utilized, and the mass production can be conducted, and the invention is easy to popularize and apply.

Effective monitoring of the acid / base physiology of dental plaque is considered in caries risk assessment. The invention provides a methodology for caries risk assessment and a kit of biochemical tests for acid / alkali generation in dental plaque and in saliva as a screening instrument for identifying subjects with caries. The invention provides simple chair-side tests that measure the ability of dental plaque and / or saliva to metabolize sugars concomitantly with the ability to metabolize urea and other salivary nitrogenous substrates.