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15 results about "Immune resistance" patented technology

Adaptive immune resistance is a process in which the cancer changes its phenotype in response to a cytotoxic or proinflammatory immune response, thereby evading it.

Medical image-based tumor microenvironment state analysis method, system and device

PendingCN122244494AEfficient and accurate determinationMedical data miningBiostatisticsImmune resistanceImaging processing
This application discloses a method, system, and device for analyzing the state of the tumor microenvironment based on medical images, relating to the field of medical image processing technology. First, by acquiring medical images and gene expression data of related tissues within those images, the medical images are preprocessed to obtain image patches, and semantic features of these patches are extracted. An algorithm is then used to calculate a predefined immune resistance mechanism that matches the gene expression data as the dominant immune resistance mechanism. This dominant immune resistance mechanism is then set as a supervisory label for the model, and a prediction model is constructed. The model is trained using a large amount of data, and the medical image to be analyzed is input into the trained prediction model to obtain the predicted category of the resistance mechanism. This application can accurately predict the resistance mechanism of pathological tissues based on medical images and their related gene expression data.
Owner:NAT HEALTH COMMISSION INST OF SCI & TECH

Application of zymosan in promoting plant growth and inducing immune resistance

The invention discloses application of zymosan in promoting plant growth and resisting diseases, and belongs to the field of agriculture. The invention provides an application of zymosan in promoting plant growth, wherein the use concentration is 300-800 ppm. After the zymosan is applied, the plant height growth rate of the plant is increased by 10%-25%, and the root system number, the root system length or the leaf area are remarkably increased. The invention also provides a plant growth promoting composition containing the zymosan. The zymosan also has the activity of inducing plant immune resistance. The zymosan disclosed by the invention has dual functions of promoting growth and resisting diseases, is environment-friendly and high in safety, and has a wide application prospect in green agriculture and sustainable agriculture.
Owner:NORTHWEST A & F UNIV

Camellia japonica endophytic bacteria, bacterial agent and anti-influenza a virus application thereof

ActiveCN120041354Blow toxicityeliminate side effectsBacteriaMicroorganism based processesInflammatory factorsImmune resistance
The application provides a camellia plant endophytic bacteria, a bacterial agent thereof and an anti-influenza virus A application; the camellia plant endophytic bacteria is Bacillus thuringiensis, which is preserved in the China General Microbiological Culture Collection Center with a preservation number of CGMCC No.32945. The fermentation product of the strain shows good antiviral activity in in vitro and in vivo experiments, can effectively inhibit the replication of influenza virus, and protect infected mice from lethal influenza virus; also shows the effect of regulating immune response, enhances the secretion of IFN-gamma by down-regulating the secretion of pro-inflammatory factors such as IL-6 and IL-10, thereby improving the immune resistance of the body.
Owner:GUANGXI UNIV

Application of 2, 4-di-tert-butylphenol nanoemulsion as plant immune resistance inducer

PendingCN121694311ABiocidePlant growth regulatorsBiotechnologyTert butyl phenol
The invention relates to the technical field of agricultural biotechnology and plant protection, and discloses application of 2, 4-di-tert-butylphenol nanoemulsion as a plant immune resistance inducer, the 2, 4-di-tert-butylphenol nanoemulsion comprises the following components: 2, 4-di-tert-butylphenol, ethyl acetate, Tween 80 and water, the 2, 4-di-tert-butylphenol, ethyl acetate, Tween 80 and water are added into the 2, 4-di-tert-butylphenol nanoemulsion for the first time, and the 2, 4-di-tert-butylphenol nanoemulsion is added into the plant immune resistance inducer According to the present invention, 2, 4-di-tert-butylphenol is developed into the plant immune resistance inducer, the problems of poor water solubility and low bioavailability of the compound are solved by using the nano-emulsion technology, the brand new application field of the compound is expanded, and the nano-emulsion belongs to a thermodynamic stable system, is not easily layered or precipitated after long-term storage, and has good storage and transportation stability.
Owner:INNER MONGOLIA UNIVERSITY

Natural porphin salt and use thereof as plant growth regulator and immune resistance inducer

The present disclosure provides a natural porphin salt and a use thereof as a plant growth regulator and a plant immunity inducer. The porphin salt includes a salt of porphin or a salt of chlorin. Compared with the prior art, the porphin salt of the present disclosure has high stability, exhibits a stable and reliable quality during long-term storage, has a long shelf life, and is easy to carry and transport. The porphin salt has prominent water solubility, is easy to prepare into an aqueous solution with a stable content, and exhibits excellent reproducibility when applied to the field. The porphin salt can be conveniently applied at a low concentration with a strong activity and a prominent control effect. Raw materials for preparing the porphin salt are natural and widely available. The preparation of the porphin salt is emission-free, pollution-free, energy-saving, and eco-friendly. In particular, when used as a plant immunity inducer, the porphin salt exhibits a significantly better control effect than the existing products.
Owner:NANJING BAITE BIOLOGICAL ENG

Biotransformation preparation method of curdlan oligosaccharide and application of curdlan oligosaccharide in preparation of immune induced resistance products

PendingCN121555596AFungiBiocideImmune resistanceFood grade
The invention belongs to the field of preparation and application of oligosaccharide active substances, and provides a biotransformation preparation method of curdlan oligosaccharide and application of the curdlan oligosaccharide in preparation of immune induced resistance products. According to the preparation method, a composite oxidation hydrolysis technology is adopted, food-grade and high-purity raw materials are selected, and the curdlan oligosaccharide with the polymerization degree of 4-10 is successfully prepared through the steps of reagent addition in a specific proportion, strict hydrolysis condition control, concentration, impurity removal, membrane filtration purification and the like. After the oligosaccharide is prepared into a solution, the solution is sprayed on Arabidopsis thaliana leaves, the salicylic acid signal channel of Arabidopsis thaliana can be obviously activated, and the activity of related enzymes in the Arabidopsis thaliana can be improved, so that the immune system of plants is activated, the invasion of pathogenic bacteria is effectively resisted, and the disease index is reduced. Therefore, the curdlan oligosaccharide is an efficient plant immune resistance inducer material. The invention not only provides a new effective substance for the field of plant immune induced resistance, but also develops a corresponding preparation method, and shows a wide application prospect.
Owner:QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES) +4

Comprehensive cultivation method for preventing and treating diseases and insect pests of fructus forsythiae

PendingCN121713804ABiocidePlant growth regulatorsContinuous croppingImmune resistance
The invention discloses a comprehensive cultivation method for preventing and controlling diseases and insect pests of forsythia suspensa, and relates to the technical field of forsythia suspensa planting, and the method comprises the following steps: S1, selecting a land parcel meeting the growth requirements of forsythia suspensa, and completing deep ploughing, fertilization, furrowing and necessary soil disinfection; qualified cutting slips are selected, treated and then subjected to cuttage, and seedlings are cultivated through seedling management; seedlings obtained by seedling raising are transplanted and planted according to specified density in a proper period; performing water and fertilizer management and pruning management to maintain the robust growth state of plants; s2, preparing a composite immune resistance inducer; s3, spraying an immune resistance inducer in a programmed manner; s4, synergistically implementing physical prevention and control and biological prevention and control measures; according to the cultivation method, through scientific site selection and standardized basic cultivation, and programmed spraying of the complex immune resistance inducer in a specific ratio in a key phenological period, the pain points of pathogenic bacteria accumulation, easy waterlogging in summer and the like of continuous cropping plots can be solved in a targeted manner, the stress resistance of forsythia suspensa is effectively improved, leaf diseases and chewing pests are effectively prevented, and the yield is increased.
Owner:TIANSHUI AGRI SCI RES INST

A bionic vaginal fluid with moisturizing and anti-inflammatory effects and a preparation method and application thereof

The present application belongs to the technical field of raw materials for female and gender external products, and particularly relates to a bionic vaginal fluid with moisturizing and anti-inflammatory effects and a preparation method and application thereof. The bionic vaginal fluid comprises the following components in parts by weight: polysaccharide of Phaeolepiota aurea 0.1-2 parts and succinyl polysaccharide 0.1-1 part. The present application innovatively uses the combination of polysaccharide of Phaeolepiota aurea and succinyl polysaccharide to prepare the bionic vaginal fluid. The two components cooperate and interact with each other, can play a synergistic effect, and can significantly improve the moisturizing property and anti-inflammatory soothing effect of the bionic vaginal fluid, can provide lubrication and good moisturizing feeling for the vagina, and at the same time help maintain the microecological balance in the vagina and improve the immune resistance of the vagina.
Owner:SHANGHAI DONGLIDA HEALTH RES INST CO LTD +1

Composition containing plant immune resistance inducer and chemical bactericide and application of composition in disease prevention and yield increase of corn

PendingCN121713936ABiocidePlant growth regulatorsImmune resistanceCurvularia
The invention belongs to the technical field of pesticides, and particularly relates to a composition containing a plant immune resistance inducer and a chemical bactericide and application of the composition to promotion of disease resistance and yield increase of corn. The disease index of corn southern leaf blight and corn curvularia leaf spot disease treated by the composition is low and is superior to or close to the prevention effect of a conventional chemical agent treatment group (100% color development), and the yield of corn treated by the composition per mu is increased by 9.7% or above and is close to the yield increase value of the conventional chemical agent treatment group (100% color development).
Owner:HENAN AGRICULTURAL UNIVERSITY

Health-care wine capable of resisting aging, enhancing immunity and prolonging life and preparation process of health-care wine

The invention relates to the technical field of health-care wine, in particular to health-care wine capable of resisting aging, enhancing immunity and prolonging life and a preparation process of the health-care wine capable of resisting aging, enhancing immunity and prolonging life, and the health-care wine capable of resisting aging, enhancing immunity and prolonging life is prepared from the following materials in parts by weight: a wine 1000 parts of Baijiu; animal source components: 5-8 parts of zaocys dhumnade, 5-8 parts of agkistrodon halys, 3-5 parts of deer blood powder and 2-4 parts of Chinese turtle shell; the plant source component comprises a tonifying plant source, a harmonizing plant source and an assistant plant source; according to the invention, the tonifying plant source, the harmonizing plant source and the assistant plant source are combined into the plant source component, and the plant source component and the animal source component form an anti-aging, immune and metabolic regulation network, so that the physiological function of a human body is regulated in a multi-channel manner, and the comprehensive health-care effects of resisting aging, enhancing immune resistance and prolonging life are realized.
Owner:GUIZHOU RONGXIANGTANG HEALTH IND CO LTD

HSM1 gene and application thereof in improving wheat growth period related powdery mildew resistance

PendingCN121737157APlant peptidesFermentationBiotechnologyImmune resistance
The invention relates to the technical field of crop molecular biology and molecular breeding, in particular to an HSM1 gene and application thereof in improving wheat growth period related powdery mildew resistance. The HSM1 gene provided by the invention is a powdery mildew-resistant gene explored from wild two-grain wheat, and is transferred into a common wheat variety Yangmai 158 through multiple hybridization and backcross to obtain a BC5F3 disease-resistant family 16-21, and finally the HSM1 gene is obtained. Results of the specific embodiment of the invention show that a strain with increased expression quantity of the HSM1 gene shows growth period dependent powdery mildew resistance, that is, the plant does not resist diseases in a seedling stage, but the resistance is enhanced after an elongation stage, and high resistance even immune resistance is achieved in a heading stage. The resistance mode provided by the HSM1 gene is beneficial for reducing the energy consumption caused by the expression of the anti-disease gene of the plant, and is beneficial for realizing the high-yield target.
Owner:NANJING AGRICULTURAL UNIVERSITY +1

NLR receptor and application thereof

PendingCN121628945ABacteriaPlant peptidesBiotechnologyImmune resistance
The invention discloses an application of an NLR receptor RCSP (GenBank: XAX32969.1) in endowing or enhancing immune resistance of plants, and the over-expression of the RCSP in the plants can activate ETI and generate very strong systemic resistance, so that the plants can better resist various pathogenic bacteria or viruses and the like.
Owner:CAS CENT FOR EXCELLENCE IN MOLECULAR PLANT SCI

Nutrient solution for preventing tomato phytotoxicity and preparation thereof

PendingCN121248341ASuperphosphatesMagnesium fertilisersPotassium nitrateImmune resistance
The invention discloses a nutrient solution for preventing tomato phytotoxicity and preparation thereof, and belongs to the technical field of agricultural fertilizers. The nutrient solution for preventing tomato phytotoxicity is prepared from the following raw materials in parts by mass: 10 to 15 parts of urea, 10 to 20 parts of ammonium nitrate, 10 to 15 parts of potassium fulvate, 5 to 10 parts of potassium nitrate, 10 to 15 parts of calcium superphosphate, 25 to 35 parts of arabidopsis thaliana extract, 1 to 5 parts of EDTA (Ethylene Diamine Tetraacetic Acid) manganese chelate, 1 to 5 parts of EDTA iron chelate, 5 to 10 parts of compound amino acid, 5 to 10 parts of magnesium sulfate, 10 to 15 parts of calcium nitrate, 1 to 3 parts of copper sulfate and 200 to 300 parts of water. After the nutrient solution for preventing tomato phytotoxicity is added, the growth state of plants can be adjusted, and the immune resistance of the plants is induced, so that the tolerance of tomatoes to pesticides is enhanced. Moreover, the nutrient solution has the capability of resisting broad-spectrum phytotoxicity, and has a prevention effect on various types of phytotoxicity.
Owner:SHAANXI INST OF BIOLOGICAL AGRI

Recombinant newcastle disease viruses and immunogenic compositions for use in immunizing against sars-cov-2 omicron variant

Described herein are recombinant Newcastle disease viruses ("NDVs") comprising a packaged genome, wherein the packaged genome comprises a transgene comprising a nucleotide sequence encoding a protein comprising a SARS-CoV-2 Omicron variant spike protein or portion thereof, or a derivative thereof. Also described herein are recombinant NDVs comprising a packaged genome, wherein the packaged genome comprises a transgene encoding a chimeric F protein, wherein the chimeric F protein comprises a SARS-CoV-2 Omicron variant spike protein ectodomain or a derivative thereof, and NDV F protein transmembrane and cytoplasmic domains. Further, described herein are immunogenic compositions comprising a recombinant NDV(s). The recombinant NDVs and immunogenic compositions are useful for the immunizing against SARS-CoV-2 as well as the prevention of COVID-19.
Owner:MT SINAI SCHOOL OF MEDICINE

Application of N-lauroyl isoleucine in improving resistance of rice sheath blight disease

PendingCN121986787AEasy to degradeNo residual riskBiocidePlant growth regulatorsBiotechnologyImmune resistance
The invention discloses application of N-lauroyl isoleucine to improvement of resistance to rice sheath blight disease, and relates to the technical field of plant immune resistance inducers and green agricultural invests.It is found for the first time that after plants are treated with low-concentration N-lauroyl isoleucine, systematic resistance of rice to the sheath blight disease can be induced by activating an OsNPR1-OsPR2-OsMAPK6 pathway, and therefore the N-lauroyl isoleucine can be used for improving the resistance of the rice sheath blight disease. The N-lauroyl isoleucine can be used as an effective component of a plant immune resistance inducer. The plant immune resistance inducer prepared by taking the N-lauroyl isoleucine as an effective component can be used for preventing and treating through a spraying method, is high in operability, simple and quick, and can be used for effectively preventing and treating the expansion and spreading of diseases. In addition, the N-lauroyl isoleucine is a biological endogenous metabolite, is easy to degrade and has no residual risk; and the N-lauroyl isoleucine is low in cost and conforms to the current agricultural sustainable development direction.
Owner:YUELU MOUNTAIN LAB