72 results about "Azoxystrobin" patented technology

The invention discloses a high-yield gastrodia elata planting method based on Tilia brachypoda fungus material optimization and seed ramie stress resistance activation. According to the high-yield gastrodia elata planting method based on Tilia brachypoda fungus material optimization and seed ramie stress resistance activation, yield increase and quality improvement are achieved through fungus material composite strengthening treatment and a composite strain synergistic inoculation technology. The method comprises the following steps: (1) fermenting a tilia brachypoda substrate by lactobacillus plantarum and soaking in a nano-composite nutrient solution to form a high-activity bacterial material; (2) nitrogen-fixing bacteria, disease-resistant actinomycetes and armillaria mellea are mixed and inoculated according to the proportion of 3: 1: 1, nitrogen supply is improved, and the occurrence rate of black rot is reduced; 3) activating a GASA stress-resistant gene of the seed hemp through a pulsed electric field (5 kV / cm, 10 microseconds), and enabling the germination rate to reach 88.5% in combination with a calcium signal channel strengthening technology; according to the method, the yield per mu of gastrodia elata is increased by 30%-40%, the gastrodin content is increased by 30% or above, the chemical pesticide dosage is reduced by 55%, the strain passage purity is stable, the method is suitable for large-scale planting in multiple climate areas, and an innovative solution is provided for green production of traditional Chinese medicinal materials.

The present application relates to the field of microbiological technology, and particularly relates to a pathogenic bacterium causing root rot symptoms of red heart disease of Astragalus membranaceus and application thereof, the pathogenic bacterium is Fusarium sp. Fusarium sp. FUS-001-2025, preserved in China General Microbiological Culture Collection Center on March 16, 2026, with the preservation number of CGMCC No. 42529; it is determined to be a new recorded strain of Fusarium sp. through morphological and molecular identification, and the bactericide sensitivity determination shows that 25% silthiofam·prochloraz has the strongest inhibition effect, 25% bromothalonil, 50% azoxystrobin and 70% methylthiophanate have significant inhibition at high concentrations. The present application provides an important pathogenic bacterium resource for the pathogenic mechanism, disease resistance evaluation and development of control agents of red heart disease of Astragalus membranaceus.

The invention discloses a bactericide composition for preventing and treating earthen archaeological site mushroom diseases and application of the bactericide composition, triazole bactericides and methoxyl acrylate bactericides are used as active ingredients and compounded with a synergist, the mass ratio of triazole to azoxystrobin is 1: 1-1: 9, the content of the synergist is 0.01%-0.1% of the total mass, the content of the methoxyl acrylate bactericides is 0.01%-0.1% of the total mass, and the content of the methoxyl acrylate bactericides is 0.01%-0.1% of the total mass. The composition shows a remarkable synergistic effect, the FIC index is smaller than or equal to 0.5, and the composition has an efficient killing effect on spores, hyphae and sporocarps of common mushrooms in earthen ruins. The composition ensures safety to a ruins body material, shows a color difference value [delta] E < 3, a penetration depth greater than 5 cm, and maintains long-term stability in a humid environment for at least 12 months. The bactericide formula is systematically optimized for earthen ruins mushroom diseases for the first time, and various macro fungi including coprinus brachypoda, coprinus comatus, pleurotus ostreatus and pleurotus citrinopileatus are effectively prevented and treated. Through laboratory screening, synergistic effect testing, permeability and safety evaluation and field application verification, the composition has an excellent prevention and treatment effect.

Provided is a synthesis method for azoxystrobin, comprising: in a water-oil system of an organic solvent and an aqueous solution of trimethylamine, a compound represented by formula I reacts with 2-cyanophenol to obtain azoxystrobin, wherein the molar ratio of the compound represented by formula I to trimethylamine is 1:(0.96-2). The synthesis method has high reaction efficiency, does not produce CO2, avoids the risks of entrainment and overflow, reduces the generation of side reactions and solid waste emissions and is environmentally friendly. In addition, the method does not require the use of solid sodium carbonate or potassium carbonate, and the material reaction system is an oil-water reaction system, so that the reaction efficiency is greatly improved, and the yield can also be maintained at 95% or more, thereby taking both the efficiency (timeliness) and the yield into account and easily achieving continuous reaction, and thus providing technical support for intelligent and unmanned production. Moreover, since trimethylamine can be recycled, the use of one raw material is reduced, and further there is no need for complicated treatment for mixed salts and waste water thereof, thereby significantly reducing the energy consumption.

The application relates to the technical field of anti-transpiration agents, and discloses application of a compound in the field of plant drought resistance and a plant drought resistance preparation. At least one of the compounds of pyrisoxazole, dinotefuran, azoxystrobin and fluopicolide and the plant drought resistance preparation can significantly reduce a water transpiration rate, improve the resistance of plants to general water shortage, and reduce economic losses of plants caused by drought and water shortage.

A method for preparing a cyclodextrin-metal-organic framework (MOF) nano-sustained-release pesticide, the cyclodextrin-metal-organic framework nano-sustained-release pesticide prepared by this method, and the application of this cyclodextrin-metal-organic framework nano-sustained-release pesticide in fruit preservation. The preparation method includes 1) the preparation of γ-CD-MOF; 2) the preparation of a mixture of γ-CD and azoxystrobin; and 3) the preparation of a γ-CD-MOF / azoxystrobin nano-sustained-release pesticide. Biocompatible γ-cyclodextrin is used as the organic ligand, with K... + γ-CD-MOF materials were prepared using ion centers. The synthesis process conditions were optimized, and a universal synthesis method was established. Azoxystrobin fungicide was loaded into γ-CD-MOF materials to prepare a slow-release pesticide. The process conditions were optimized, and when the solvent ratio was 10:6, the material morphology was a uniform cubic shape with an average particle size of 1.93 μm.

The invention belongs to the technical field of pesticides, and relates to 11 bactericide compositions for mainly preventing and treating crop diseases caused by pyricularia oryzae and colletotrichum gloeosporioides. The compound YJY-22 provided by the invention is novel in structure and unique in action mode, and has no cross resistance with isoprothiolane, fenoxanil, pyraclostrobin, tricyclazole, azoxystrobin, mancozeb, captan, difenoconazole, prochloraz, chlorothalonil and tebuconazole. As the action mechanism of the compound YJY-22 is different from that of the medicament, and the compound YJY-22 and the medicament have no cross resistance, the compound YJY-22 and the medicament are compounded, so that the sterilization range can be expanded, the sterilization effect can be enhanced, the drug resistance of phytopathogen can be delayed, the safety to crops is good, the prevention and control spectrum is expanded, and the requirements of pesticide reduction and synergism are met.

The invention relates to a fungicide composition for preventing and treating peanut root rot as well as preparation and application of the fungicide composition. The invention aims to solve the technical problems of unstable field control effect, high chemical pesticide residue and high drug resistance risk of biological control in peanut root rot control. Bacillus velezensis YJ02 with good biocompatibility is compounded with azoxystrobin (a biological fungicide generates antibacterial substances and induces plant defensive enzymes, and a chemical fungicide is combined to rapidly inhibit respiration of pathogenic bacteria) to prevent and treat peanut root rot; the technical effects that the efficient synergistic control effect (for example, the control effect reaches up to 86.79%) is achieved, the application amount of chemical pesticides is reduced (for example, the dosage of azoxystrobin is only 9.82% of the conventional dosage), the drug resistance risk of pathogenic bacteria is effectively reduced, the morbidity and disease index are reduced, and environment friendliness is achieved are achieved, and high economic benefits and social benefits are achieved.

The invention provides an epoxiconazole azoxystrobin nano suspending agent as well as a preparation method and application thereof, and belongs to the technical field of pesticides. The epoxiconazole and azoxystrobin nano suspending agent is prepared from the following components in percentage by mass: 5 to 20 percent of epoxiconazole, 10 to 30 percent of azoxystrobin, 2 to 5 percent of a wetting agent, 6 to 12 percent of a dispersing agent, 0.2 to 2 percent of a thickening agent, 1 to 5 percent of an anti-freezing agent, 0.01 to 0.5 percent of a preservative, 0.1 to 2 percent of a de-foaming agent and the balance of water. The epoxiconazole and azoxystrobin nano suspending agent is prepared by compounding epoxiconazole and azoxystrobin, has good particle size stability (the particle size D90 is less than or equal to 500nm), and can keep good particle size over-time stability under a low dilution multiple (within 100 times). The nano suspending agent can significantly enhance the prevention and treatment effect on fungal diseases, expand the prevention and treatment spectrum, delay the development of resistance to a single effective component, adapt to flight control pesticide application, and can give full play to the use advantages of the nano suspending agent.

The application discloses a propiconazole-azoxystrobin- clothianidin seed treatment suspending agent and a preparation method and application thereof, and belongs to the technical field of pesticide preparations; the agent takes propiconazole, azoxystrobin and clothianidin as active ingredients, takes beta-nicotinamide mononucleotide (NMN) as a functional antimicrobial component, and is supplemented with styrene-maleic anhydride copolymer sodium salt, fatty alcohol polyoxyethylene ether, xanthan gum, magnesium aluminum silicate, glycerol, polydimethylsiloxane defoaming agent, sodium benzoate, polyvinyl alcohol and deionized water to prepare the agent. The application is suitable for seed coating treatment for preventing and treating rice false smut, thrips and wheat sharp eyespot and aphids; NMN promotes the accumulation of phenolic compounds in the phloem of plants, and cooperates with clothianidin on the same insecticidal target, thereby significantly improving the prevention and treatment effect on aphids and thrips; the degradation product of NMN promotes the proliferation of beneficial microorganisms in the rhizosphere, improves soil enzyme activity, and realizes soil micro-ecological restoration.

This invention relates to a hybridoma cell line that secretes a monoclonal antibody against azoxystrobin and its application, belonging to the field of immunochemistry. The hybridoma cell line of this invention was deposited on November 12, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 46742, and classified as a monoclonal cell line. The monoclonal antibody secreted by the invented hybridoma cell line exhibits good detection sensitivity (IC50) against azoxystrobin. 50 With a value of 0.049 ng / mL, it can be used for the detection of antimicrobial residues.

The invention discloses an application of micafungin in preparation of a medicine for inhibiting fungi, and an application of micafungin and trifloxystrobin combined medicine in preparation of a medicine for inhibiting fungi, especially an inhibition effect on magnaporthe oryzae. Research finds that micafungin has an inhibition effect on magnaporthe oryzae. Micafungin and trifloxystrobin are combined for use and have a synergistic effect, so that the drug resistance of the trifloxystrobin drug-resistant magnaporthe oryzae can be overcome, and the antibacterial effect on the magnaporthe oryzae is improved. Research finds that micafungin has a broad-spectrum antifungal effect and also has an inhibition effect on botrytis cinerea, fusarium moniliforme, linseed fungus and other fungi besides the inhibition effect on magnaporthe oryzae.

11 fungicide compositions mainly used for controlling crop diseases caused by Pyricularia oryzae and Colletotrichum spp.. Compound YJY-22 has a novel structure and a unique mode of action, and exhibits no cross-resistance with isoprothiolane, fenoxanil, pyraclostrobin, tricyclazole, azoxystrobin, mancozeb, captan, difenoconazole, prochloraz, chlorothalonil, or tebuconazole. Because compound YJY-22 and the described agents have different mechanisms of action and have no cross-resistance, combining compound YJY-22 and the described agents not only can broaden the antifungal spectrum and enhance antifungal efficacy, but also can delay fungicide resistance of plant pathogens, ensure high crop safety, expand the control spectrum, and meet the requirement of pesticide reduction with increased efficiency.

The application belongs to the field of metal organic framework materials (MOFs), and particularly relates to an amino-functionalized UIO-66 (Zr) and a preparation method and application thereof. The application mainly utilizes an amino ligand containing an aminobenzoic acid group and UIO-66 (Zr) to form a complex, which has good binding capacity with azoxystrobin and other pesticide molecules and saccharide substances, and can reduce the ultraviolet band gap value, so as to improve the laser desorption / ionization efficiency of the analyte. Compared with the mass spectrum peak intensity of the organic matrix, the amino-functionalized UIO-66 (Zr) material shows lower noise and detection limit and higher signal intensity in the MALDI-TOF-MS detection, which is beneficial to realize high-sensitivity and high-throughput detection of pesticides and saccharide substances.

The invention discloses AS-PCR primers and a method for detecting drug resistance of peronophythora litchii to azoxystrobin. An AS-PCR primer capable of being used for detecting whether peronophythora litchii has drug resistance to azoxystrobin or not is obtained by comparing differential sequences of a peronophythora litchii strain capable of resisting azoxystrobin and a peronophythora litchii strain sensitive to azoxystrobin, and a method for detecting the drug resistance of peronophythora litchii to azoxystrobin is constructed based on the AS-PCR primer. The detection specificity is good, and the sensitivity is high. The AS-PCR primer and the detection method are used for amplifying a to-be-detected strain, and if a single band with the consistent size can be obtained, the detected strain is anti-azoxystrobin peronophythora litchii. Compared with a traditional detection method, the detection method disclosed by the invention is short in time consumption, simple, convenient and feasible, is beneficial to quickly monitoring early epidemic of peronophythora litchii anti-azoxystrobin groups, and provides scientific guidance for scientific prevention and control of peronophythora litchii.

The application discloses a preparation method of flumetover intermediate (E)-(5,6-dihydro-[1,4,2]-dioxazin-3-yl)-(2-hydroxyphenyl)-methanone-O-methyl oxime, which is obtained by converting the configuration of (Z)-(5,6-dihydro-[1,4,2]-dioxazin-3-yl)-(2-hydroxyphenyl)-methanone-O-methyl oxime into (E)-(5,6-dihydro-[1,4,2]-dioxazin-3-yl)-(2-hydroxyphenyl)-methanone-O-methyl oxime by using an acidic reagent in the presence of a phase transfer catalyst. The application innovatively converts the useless (Z) structure, which is usually abandoned as an impurity, into the valuable flumetover intermediate (E) structure through configuration conversion, so that the useless substance can be turned into treasure, resources can be optimized, and the problems in the synthesis of the flumetover intermediate (E) structure in the prior art can be solved.

The application discloses a kind of azoxystrobin continuous crystallization method, belong to pesticide fungicide technical field.It includes the following steps: first crystallizer, second crystallizer, third crystallizer, fourth crystallizer head-to-tail sequentially interconnect, and from top to bottom are set, the crystal slurry in the crystallizer utilizes height difference self-flow discharge;First, the concentration is 25-30% mass concentration of butyl acetate solution containing azoxystrobin is carried out to crystal operation;After the crystal of butyl acetate solution containing azoxystrobin is precipitated, butyl acetate solution containing azoxystrobin is added to first crystallizer, temperature control is at 53-57 ℃ temperature, stays for a certain time;Then the crystal slurry is overflowed or pumped into second crystallizer, third crystallizer, fourth crystallizer in sequence and is cooled and crystallized, the crystal slurry in fourth crystallizer is overflowed or pumped into transfer tank or centrifuge, and the product is obtained after the crystal slurry is post-treated.The particle size uniformity of the crystalline crystal obtained by the continuous crystallization method provided by the application.

The invention discloses a synergistic bactericidal composition and application thereof in prevention and treatment of kidney bean diseases, and belongs to the technical field of pesticides. The active ingredients of the composition comprise citral, azoxystrobin and difenoconazole. Through a specific ratio, the three active ingredients show a remarkable synergistic effect when preventing and treating fusarium, and the problem that the prevention effect of an existing bactericide is reduced due to drug resistance is solved. The composition provided by the invention has the advantages of high efficiency, low toxicity and reduced dosage, and provides a new thought for developing a novel green compound bactericide.

The invention relates to the field of pesticide compositions, in particular to a pesticide suspending agent containing thiophanate-methyl and trifloxystrobin and a preparation method of the pesticide suspending agent. The pesticide suspending agent containing the thiophanate-methyl and the trifloxystrobin, provided by the invention, is prepared from the following raw materials in parts by mass: 5 to 6 parts of the trifloxystrobin, 40 to 42 parts of the thiophanate-methyl, 3 to 5 parts of a wetting dispersant, 2 to 3 parts of a dispersant, 1 to 3 parts of a wetting emulsifier, 1 to 2 parts of a suspending thixotropic agent, 3 to 5 parts of an anti-freezing agent, 0.1 to 0.3 part of a preservative, 0.1 to 0.3 part of a thickening agent, 0.1 to 0.3 part of a de-foaming agent and 35 to 45 parts of water. The pesticide suspending agent containing thiophanate methyl and trifloxystrobin provided by the invention is excellent in stability, low in irritation to crops and good in environmental compatibility, and has good popularization and application values.

The present application discloses a synthesis method for azoxystrobin, comprising a step of: reacting a compound of Formula I with 2-cyanophenol in a water-oil system of an organic solvent and an aqueous solution of trimethylamine to obtain azoxystrobin, wherein a molar ratio of the compound of Formula I to trimethylamine is 1:(0.96-2). The synthesis method of the present application has advantages of high reaction efficiency, no CO2 generation, avoidance of the risk of entrained overflow, reduced secondary reactions, reduced solid waste emissions, and environmental friendliness. Use of solid sodium carbonate or potassium carbonate is avoided and the material reaction system is an oil-water reaction system. The reaction efficiency is significantly improved and the yield can reach 95% or above. Both efficiency (timeliness) and yield can be taken into account, and continuous reactions can be realized easily, providing technical support for intelligent, unmanned production.

The invention relates to the technical field of pesticides, and discloses a seed treatment agent and application thereof. The seed treatment agent comprises an active component and an auxiliary agent, wherein the active ingredients are prepared from flonicamid, thiram and azoxystrobin. The invention also relates to application of the seed treating agent in prevention and treatment of diseases and insect pests of food crops and oil crops. The invention provides the seed treatment agent containing the three active ingredients of flonicamid, thiram and azoxystrobin, the product stability is improved, the seed treatment agent can tolerate high and low temperature intervals, meanwhile, the product suspension rate is high, the coating falling rate is low, the seed treatment safety is good, and the seed treatment agent can be subsequently used in different countries and regions and is beneficial to large-scale popularization and application. The seed treatment agent provided by the invention is simple in preparation process and simple and convenient to operate.

The application discloses a special medicine fertilizer of metalaxyl-M and azoxystrobin, and a preparation method and application thereof, and belongs to the technical field of special medicine fertilizers. The special medicine fertilizer of metalaxyl-M and azoxystrobin is composed of the following components in percentage by weight: 0.1-2% of metalaxyl-M, 0.1-2% of azoxystrobin, 1-10% of fungicide metabolite, 0.5-1.5% of sophorose lipid, 0.2-3% of ethylene glycol, 5-20% of nitrogen, phosphorus and potassium, 0.1-2% of calcium, 0.1-2% of magnesium, and the balance of water-soluble organic matter filler. The fungicide metabolite and the sophorose lipid prepared by the specific method are synergistic with the metalaxyl-M and the azoxystrobin, so that the purpose of reducing the application amount of the pesticide fertilizer and increasing the efficiency is achieved.

The invention relates to the technical field of resource recovery of products in bactericide synthesis, and discloses a resource recovery method of an azoxystrobin mother liquor desolventizing material. The method comprises the following steps: by taking an azoxystrobin mother liquor desolventizing material as a raw material, sequentially carrying out more than two times of alkali washing impurity removal, more than two times of acid washing impurity removal, water washing impurity removal, desolventizing, devitrifying, separating and recrystallizing to obtain an azoxystrobin finished product. The method solves the problems of high treatment cost and resource waste caused by the fact that the existing one-pot synthesis of azoxystrobin mother liquor contains many impurities, azoxystrobin cannot be recycled and can only be treated as hazardous waste. The separation and recovery process provided by the invention is mild in condition and has relatively high economic and social benefits.

The invention relates to a synthesis method of an azoxystrobin intermediate, and belongs to the technical field of organic synthesis.The synthesis method comprises the steps that benzofuranone serves as a raw material and is directly condensed with formate under the action of alkali, then dimethyl sulfate is methylated, and 3-(alpha-methoxyl) methylene benzofuranone is obtained. The use of expensive trimethyl orthoformate is avoided, and the cheap and easily available formate is adopted, so that the raw material cost of the azoxystrobin intermediate is greatly reduced, and the method is simple in process route, high in yield and suitable for industrial production.

This invention relates to a method for synthesizing azoxystrobin, belonging to the field of organic synthesis technology. The method uses 2-(2-(chloromethyl)phenyl)-3-methoxyacrylonitrile and 2-hydroxy-6-trifluoromethylpyridine as raw materials, condensing them under alkaline conditions to obtain an etherified intermediate, which is then directly hydrolyzed and esterified with methanol under acidic conditions to obtain azoxystrobin. This method avoids the use of expensive 3-isochloroketone as a raw material, using inexpensive 2-(2-(chloromethyl)phenyl)-3-methoxyacrylonitrile prepared from o-methylphenylacetonitrile as the key fragment, further reducing the cost of azoxystrobin raw materials. Furthermore, the process route is simple, the yield is high, and it is suitable for industrial production.

This invention discloses a mixing vessel for producing suspensions containing pyraclostrobin and fludioxonil, belonging to the field of material mixing technology. It includes a mixing vessel body with a lid, and a drive frame inside the mixing vessel body. The drive frame is equipped with a stirring assembly, a liquid-liquid exchange assembly, and an external liquid-inward pushing assembly. The stirring assembly is located in the middle of the mixing vessel body to continuously stir the suspension. This invention utilizes the liquid-liquid exchange assembly, employing the reciprocating motion of a piston within the exchange plunger body, to forcibly draw liquid from the bottom of the vessel body to the surface for discharge, forming a forced vertical circulation. This allows newly added pyraclostrobin technical, thickeners, defoamers, and other lightweight materials to be quickly carried below the liquid surface, preventing prolonged floating, excessively high local concentrations, and the formation of clumps (fish eyes). The forced vertical circulation and horizontal pushing significantly shorten the overall mixing time and significantly reduce energy consumption.

The invention discloses a pesticide synergist and a preparation method thereof. The synergist is prepared from 7-9 parts of potassium oleate, 1-2 parts of dipotassium phosphate and 1-2 parts of 2-hydroxy-4-methylvaleric acid according to a specific mass ratio. The preparation method comprises the following steps: stirring and mixing the components at normal temperature until the components are completely dissolved to form a homogeneous solution. The synergist disclosed by the invention can be compounded with chemical pesticides such as triadimefon, carbendazim and azoxystrobin for use, and by enhancing the attachment and permeation of the pesticides on the surfaces of plants and the binding efficiency of the pesticides and pathogenic bacteria targets, the control effect of 90% or above can be still maintained under the condition that the dosage of the chemical pesticides is reduced by 50%-80%, and pesticide residues and environmental risks are remarkably reduced. The invention has the advantages of easily available raw materials, simple process and low cost, is suitable for large-scale production, and has important significance for realizing agricultural pesticide reduction and synergism and sustainable development.

This invention relates to a method of controlling, limiting or preventing an infestation of a plant by Oomycetes, which comprises applying to propagation material of said plant, a pesticidal combination comprising a phosphorus-based compound as active ingredient A, and an active ingredient B selected from acibenzolar-S-methyl, fludioxonil, fluxapyroxad, inpyrfluxam, mefentrifluconazole, prothioconazole, sedaxane, triticonazole, oxathiapiprolin, fluoxapiprolin, azoxystrobin, difenoconazole, fluopyram, ipconazole, metyltetraprole, silthiofam, dimethomorph, thiophanate-methyl, natamycin, benzovindiflupyr, pydiflumetofen, picarbutrazox, isocycloseram, cyclobutrifluram, broflanilide, thiamethoxam, imidacloprid, clothianidin, cyantraniliprole, chlorantraniliprole, tetraniliprole, fipronil, and any mixture thereof.

The invention discloses bacillus velezensis S44 mediated chitosan nano-particles as well as a preparation method and application of the bacillus velezensis S44 mediated chitosan nano-particles. The preparation method of the chitosan nanoparticles comprises the following steps: inoculating bacillus velezensis S44 into an LB culture medium, culturing for 36-60 hours, and filtering to remove cells to obtain a filtered supernatant; uniformly mixing the filtered supernatant and a chitosan solution, and incubating for 36 to 60 hours, so as to obtain chitosan nanoparticles; the bacillus velezensis S44 is preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No: 66680. The preparation method is convenient and environmentally friendly, the obtained chitosan nanoparticles (S44-CNPs) are small in particle size (1t, 100 nm) and excellent in antibacterial activity, are equivalent to common pesticide azoxystrobin and are higher than common TPP-CNPs nanoparticles, and the huge potential of marine microorganism natural products for green synthesis of novel nano pesticides is proved.