The invention discloses an ultra-low-capacity liquid preparation containing epoxiconazole, which uses epoxiconazole, or a compound of epoxiconazole and active component II as the active ingredient, and is prepared into an ultra-low-volume liquid preparation by adding auxiliary agents and solvents; The active ingredient II is prochloraz, propiconazole, difenoconazole, chlorothalonil, myclobutanil, ricebendazol, thifuramide, rice blastamide, isofridazine, fluazinam and enoxim Any one or both of the strobilurin. The invention is suitable for ultra-low-capacity spraying, low-capacity spraying and electrostatic spraying, and is used for preventing and controlling diseases of large-area planted crops such as rice, corn, wheat, fruit trees, cotton, vegetables, rubber trees, tea trees, forest trees and sugarcane. The invention has the advantages of high work efficiency, quick effect, long duration of effect, water saving, synergistic effect and the like.