The invention discloses a Chinese-Western compound medicine preparation for treating pseudomembranous enteritis. The Chinese-Western compound medicine preparation comprises traditional Chinese medicine components and Western medicine components, wherein the traditional Chinese medicine components are prepared by mainly extracting the following components: papilionaceae mucuna cochinchinensis, phoenix dactylifera, brassica caulorapa, tofieldia divergens, syzygium buxifolium, corn cob, flower of potentilla fruticosa, oreas martiana, glycine max, bidens tripartita, herb of marsh orchis, tofieldia divergens, polytrchum commune, boschniakia himalaica, denseflower blumea herb, rhynchelytrum repens, polycarpaea corymbosa, myriaceis nepalensis, vaccinium fragile and boenninghausenia albiflora; the Western medicine components comprise pectinesterase, magnesium chloride, vitamin k, antibiotic constituents, iron, thiamine, pancreatic enzyme, ceftriaxone sodium and probiotics. According to the Chinese-Western compound medicine preparation, the traditional Chinese medicine therapy and the Western medicine therapy are combined, the effects of warming the middle, tonifying qi, invigorating the spleen for eliminating dampness, nourishing yin, clearing away heat, warming the kidney, tonifying deficiency, clearing heat, removing toxicity, diminishing inflammation, and relieving pain are achieved, harmful bacteria in intestinal tract can be eliminated, the action of bacterial toxin is weakened, the growth of normal flora in intestinal tract is facilitated, the digestion function is improved, the immunity of the whole body is adjusted, the curative effect to the pseudomembranous enteritis is definite, and the Chinese-Western compound medicine preparation takes effect quickly.