3 results about "Chronic otitis" patented technology

The invention relates to the field of medical application of hydrogel, in particular to light-operated hydrogel, a preparation method of the light-operated hydrogel and application of the light-operated hydrogel to treatment of chronic otitis media, and the light-operated hydrogel is prepared by taking gelatin methacryloyl derivatives GelMA and sulfonated chitosan methacryloyl derivatives SCSMA as main framework materials and mixing the gelatin methacryloyl derivatives GelMA and the sulfonated chitosan methacryloyl derivatives SCSMA as auxiliary framework materials. The SCSMA is prepared by introducing a methacryloyl group on a sulfonated chitosan SCS molecular chain, so that the SCSMA is endowed with photo-crosslinking capability, and the SCSMA and GelMA form a three-dimensional network structure under an illumination condition; ofloxacin is loaded on the light-operated hydrogel, LAP is added for realizing a light cross-linking reaction, and CaCl2 is added as a divalent ion regulating agent for enhancing the network stability and regulating and controlling the drug release behavior; the hydrogel disclosed by the invention can exist in a middle ear cavity for a long time and is gradually degraded, meanwhile, the sustained release of a local antibacterial drug is realized, and the problems of high flowability, short drug effect maintaining time, limited local anti-infection effect and the like of traditional ear drops are solved.

The invention discloses a chronic otitis media CT report automatic generation system based on a visual-language large model, and belongs to the technical field of radiation medicine. The system comprises a data acquisition and processing module for acquiring image data and text data and preprocessing the data; the vision-language large model training module is used for inputting the preprocessed data into a vision-language large model for training and adjusting and optimizing model parameters; and the report generation interaction module is used for generating a structured report by utilizing the trained vision-language large model. According to the system, the visual-language large model is applied to the field of CT report generation and typing diagnosis of chronic otitis media for the first time, the technical blank in the field is filled, and a new path is developed for intelligent diagnosis of chronic otitis media.

This invention discloses a traditional Chinese medicine composition for improving otitis media, belonging to the field of traditional Chinese medicine health care technology. Addressing the shortcomings of Western medicine treatments for otitis media, which often lead to microcirculatory abnormalities and recurring symptoms, and the limitations of traditional Chinese medicine's reliance on bitter and cold herbs to block ear orifices and treat only the symptoms without addressing the root cause, this invention is based on a precise formulation of the core pathogenesis of liver and gallbladder microcirculatory disorders and gallbladder meridian stagnation and heat disturbing the ear orifices. The core ingredients of this composition are lotus leaf, angelica dahurica, jujube seed, gardenia, bergamot, and platycodon, with a scientifically reasonable ratio and mild medicinal properties. In the formula, bergamot acts as the principal ingredient to soothe the liver and gallbladder; lotus leaf and gardenia act as assistant ingredients to clear heat and promote diuresis; angelica dahurica opens the orifices and drains pus; jujube seed relieves spasms and calms the mind; and platycodon acts as the guiding ingredient to carry the medicine upwards and relax blood vessels. The synergistic effect of these herbs counteracts the vasoconstrictive side effects of bitter and cold herbs and Western medicine. This invention can improve liver and gallbladder microcirculation and inhibit the release of inflammatory factors, fundamentally resolving symptoms such as ear fullness, ear pain, and middle ear effusion caused by acute and chronic otitis media, while also improving problems such as bitter taste in the mouth and insomnia caused by liver and gallbladder stagnation and heat. This composition has significant therapeutic effects, a low recurrence rate, and no toxic side effects. It can be formulated into various preparations to suit long-term conditioning for various populations, thus making up for the technical shortcomings of existing treatment options.