146 results about "Dry mouth" patented technology

The invention is directed to manufacturing and testing methods of electronic intraoral devices for diagnose, monitor and treat local and systemic diseases and conditions for humans and animals. More specifically, the current invention deals with manufacturing techniques, testing methods and a testing apparatus of mainly three types of intra-oral devices: (a) electro-stimulators for various applications such as treatment of dry mouth by stimulating saliva secretion, apnea, sleeping disorders, eating disorders (obesity, anorexia, etc.) dysphagia and others, (b) drug delivery devices; and (c) bio-sensing and monitoring devices. The common parts or the devices are: (1) art electronic module embedded in the device: (2) or a power source being embedded in the device; (3) the devices (or part of them) being placed in the oral cavity.

A once-a-day oral milnacipran modified release formulation has been developed. The formulation comprises an extended release dosage unit (optionally containing the immediate release portion) coated with delayed release coating. The milnacipran composition, when administered orally, first passes through the stomach releasing from zero to less than 10% of the total milnacipran dose and then enters the intestines where drug is released slowly over an extended period of time. The release profile is characterized by a 0.05-4 hours lag time period during which less than 10% of the total milnacipran dose is released followed by a slow or extended release of the remaining drug over a defined period of time. The composition provides in vivo drug plasma levels characterized by Tmax at 4-10 hours and an approximately linear drop-off thereafter and Cmax below 3000 ng / ml, preferably below 2000 ng / ml, and most preferably below 1000 ng / ml. The composition allows milnacipran to be delivered over approximately 24 hours, when administered to a patient in need, resulting in diminished incidence or decreased intensity of common milnacipran side effects such as sleep disturbance, nausea, vomiting, headache, tremulousness, anxiety, panic attacks, palpitations, urinary retention, orthostatic hypotension, diaphoresis, chest pain, rash, weight gain, back pain, constipation, vertigo, increased sweating, agitation, hot flushes, tremors, fatigue, somnolence, dyspepsia, dysoria, nervousness, dry mouth, abdominal pain, irritability, and insomnia.

An oral care composition for the treatment of dry mouth comprising a polyethylene oxide with a molecular weight from about 200,000 to about 7,000,000, an anti-bacterial agent, and a sensate.

A once-a-day oral milnacipran pulsatile release composition has been developed that releases the drug in spaced apart “pulses”. The dosage forms are comprised of first, second and optional third dosage units, with each dosage unit having a different drug release profile. This dosage form provides in vivo drug plasma levels characterized by Cmax below 3000 ng / ml, preferably below 2000 ng / ml, and most preferably below 1000 ng / ml. The composition provides pulsatile release of milnacipran to produce a therapeutic effect over approximately 24 hours, when administered to a patient in need, resulting in diminished incidence or decreased intensity of common milnacipran side effects such as sleep disturbance, nausea, vomiting, headache, tremulousness, anxiety, panic attacks, palpitations, urinary retention, orthostatic hypotension, diaphoresis, chest pain, rash, weight gain, back pain, constipation, vertigo, increased sweating, agitation, hot flushes, tremors, fatigue, somnolence, dyspepsia, dysoria, nervousness, dry mouth, abdominal pain, irritability, and insomnia.

An anti-cough, anti-tussive, and throat soothing synergistic herbal formulation comprising of an extract of Piper cubeba, Glycyrrhiza glabra, Acorus calamus Alpinia galanga, Zingiber officinale and pharmaceutically acceptable additives as a syrup, lozenges or chewable tablets for preventing cracking of voice, dryness of mouth and toning of voice, vocal cord; the present invention also provides a method of preparation of this formulation.

A combination drug therapy can be administered to patients to treat xerostomia or dry mouth or Sjogren's syndrome in the form of orally dissolving film or orally disintegrating tablets. Some of the drugs could be synthetic origin and some drugs are obtained from natural sources.

A once-a-day oral milnacipran modified release formulation has been developed. The formulation comprises an extended release dosage unit (optionally containing the immediate release portion) coated with delayed release coating. The milnacipran composition, when administered orally, first passes through the stomach releasing from zero to less than 10% of the total milnacipran dose and then enters the intestines where drug is released slowly over an extended period of time. The release profile is characterized by a 0.05-4 hours lag time period during which less than 10% of the total milnacipran dose is released followed by a slow or extended release of the remaining drug over a defined period of time. The composition provides in vivo drug plasma levels characterized by Tmax at 4-10 hours and an approximately linear drop-off thereafter and Cmax below 3000 ng / ml, preferably below 2000 ng / ml, and most preferably below 1000 ng / ml. The composition provides a therapeutic effect over approximately 24 hours, when administered to a patient in need, resulting in diminished incidence or decreased intensity of common milnacipran side effects such as sleep disturbance, nausea, vomiting, headache, tremulousness, anxiety, panic attacks, palpitations, urinary retention, orthostatic hypotension, diaphoresis, chest pain, rash, weight gain, back pain, constipation, vertigo, increased sweating, agitation, hot flushes, tremors, fatigue, somnolence, dyspepsia, dysoria, nervousness, dry mouth, abdominal pain, irritability, and insomnia.

An anti-intoxication composition and method of making and using are provided for treating and preventing drinker's remorse and other toxic effects of excessive alcohol consumption by humans. The anti-intoxication composition is an acidic mixture containing sweeteners, flavoring agents, food additives and a processed mixture of metallic salts, sulfuric acid, ammonium sulfate and water. When the anti-intoxication composition is ingested, it promotes the beneficial metabolism of alcohol, primarily ethanol, in the body. The beneficial metabolism results in the conversion of alcohol to amino acids and eliminates the toxic reactions of a hangover, including, but not limited to, a pounding headache, nausea, dry mouth, shaking hands, hypersensitivity to bright lights and sounds.

The present invention relates to a method, preferable an oral method, for treating urinary disorders, such as unstable or overactive bladder, while minimizing the occurrences of dry mouth, dyspepsia and reduced stream of tears. The methods of the present invention comprise orally administering to a mammal, preferably a human, a pharmaceutically effective dose of an antimuscarinic agent, such as tolterodine, when needed, whereby a symptomatic relief of urgency and / or frequency is achieved.

The invention discloses a traditional Chinese medicinal composition having functions of enriching yin and nourishing kidney as well as a preparation method and application of the traditional Chinese medicinal composition. The active ingredient of the traditional Chinese medicinal composition is prepared from the following raw materials in parts by weight: 1-5 parts of fruit of Chinese wolfberry, 1-5 parts of black sesame, 1-5 parts of mulberry, 1-5 parts of rhizoma polygonati and 1-7 parts of Chinese yam. The method comprises the steps of weighing the raw materials and decocting the raw materials together with water. According to the traditional Chinese medicinal composition disclosed by the invention, the various components take mutual synergic effect so as to achieve the functions of enriching yin and nourishing kidney, and the traditional Chinese medicinal composition is especially suitable for conditioning the deficiency of kidney and yin causing sub-health status; meanwhile, the traditional Chinese medicinal composition can be also used for relieving dizziness, headache, soreness and weakness of waist and knees, dry mouth and throat, dysphoria in chestpalms-soles and other symptoms; and in addition, since various components are prepared from both medicinal and dietary plants, the composition is sufficient in source, free from any toxic and side effects, and suitable for being taken for a long term.

An oral moisturizer is disclosed to provide relief from dry mouth. The moisturizer may be provided in different flavors that are palatable, with clinical benefits such as anti-nausea, appetite stimulant, etc., in addition to relief from the deteriorating dental effects of dry mouth. One disclosed oral moisturizer includes glycerin, xylitol, sodium hyaluronate, cetylpyridinium chloride, polysorbate surfactants and a palatable flavor.

It is intended to provide a preventive / remedy for urinary disturbance containing a compound, which shows an acetylcholine esterase inhibitory activity but substantially has no butyrylcholine esterase inhibitory activity, showing no side effect and being safe and efficacious without inhibiting the urine collection function; a preventive / remedy for dry mouth induced by the administration of a remedy for urinary disturbance and a preventive or remedy for hyperactive bladder not accompanied by dry mouth; and a method of screening a substance preventing / treating urinary disturbance without inhibiting the urine collection function characterized by comprising measuring and comparing the acetylcholine esterase inhibitory activity and the butyrylcholine esterase inhibitory activity of a test compound.

The invention discloses an officinal and edible medicine, which is prepared from bulk drugs including folium mori, chrysanthemum, almond, selfheal, mint, platycodon grandiflorum, liquorice, rhizoma phragmitis, houttuynia cordata and honeysuckle. Ten bulk drugs are matched scientifically to achieve cooperative functions and are used for treating wind-heat type common cold, clearing away heat and toxic materials, clearing away the lung-heat, and treating hot eyes, headache, cough, dry mouth, swollen sore throat, phlegm-heat, breath with cough, chronic / acute pharyngitis, acute pneumonia and the like. In addition, nine bulk drugs are officinal and edible homologous bulk drugs and mild in property, can be eaten for a long time, has no side effect and can be eaten as food and medicine. The officinal and edible medicine can be prepared into herbal tea for eliminating summer-heat by cooling, healthy beverage or various dosage forms, and has wide taking range.

The invention relates to a traditional Chinese medicine for treating pulmonary tuberculosis, which belongs to the field of medicines. The invention aims to provide the traditional Chinese medicine for treating pulmonary tuberculosis, which adopts the theory of traditional Chinese medicine and has the effects of nourishing Yin and moistening lung, regulating functions of an organism, relieving cough and reducing sputum and the like. In the invention, the prepared traditional Chinese medicine comprises the following active ingredients: dwarf lilyturf tuber, root of straight ladybell, lily, bulbus fritilariae, manyflower solomonseal rhizome, yam, sessile stemona root, bletilla and platycodon root. The traditional Chinese medicine has unique compatibility, can regulate the overall functions of the organism, has the effects of nourishing Yin and moistening lung and relieving cough and reducing sputum, has the effective rate of 83.33 percent and is used for treating pulmonary tuberculosis and yin deficiency of lungs. The traditional chinese medicine provided by the invention is used for treating symptoms containing tussiculation, night sweat, feverish palms and soles, sputum with blood streaks or blood sports, chest ache, dry mouth and lips, shortness of cough, coughing with little viscous sputum, red cheek, dry skin, red tongue and shortage of the production of body fluid, thready pulse or weak or intermittent pulse and the like.

The invention discloses a gargle for relieving thirsty symptom and a preparation method thereof. The active ingredient of the gargle comprises a linseed extract and chitosan and further comprises inorganic salt, preservative and water. The preparation method comprises the following steps of: firstly, acquiring water-soluble linseed extract; secondly, adding the components to water, stirring and dissolving at room temperature; filtering and removing impurities and finally fixing the volume to obtain the product. The invention has the features of reducing chronic and transient thirsty symptoms resulting from the situations such as diseases, taking medicine, radiotherapy and chemotherapy or aging and the like; soft and hard tissues in the oral cavity can be lubricated and wetted to relieve the thirsty symptom of a patient with thirsty symptom. Because the product has good water binding ability, the time of keeping the oral cavity wet can be prolonged and the pain, caused by the thirsty, of the patient can be eased; meanwhile, the oral cavity can be cleaned and the halitosis can be prevented. The invention has the advantages of remarkable curative effect, simple preparation method andlow cost and the like; and the gargle for relieving thirsty symptom can be used as medicine for treating thirsty symptom.

Serum compositions for application to endothelial tissue are described which contain an amniotic fluid extract in combination with embryonic stem cells. Formulations containing the serum composition are also described. The serum compositions and formulations may be used to treat conditions of the mouth such as dry mouth and mouth sores.

The invention discloses a Chinese medicine composition for curing sicca syndrome and a preparation method thereof. The Chinese medicine composition for curing the sicca syndrome mainly comprises the following components by weight: 1200-3000 parts of plaster stone, 200-450 parts of honeysuckle, 70-180 parts of the root barks of the peony trees, 70-180 parts of Indian iphigenia bulb, 200-450 parts of radix gentianae macrophyllae, 2000-450 parts of hedyotis diffusa, 200-450 parts of radix scrophulariae, 70-180 parts of radix puerariae, 200-450 parts of arisaema heterophyllum, 200-450 parts of coix Seeds, 200-450 parts of dried rehamnnia roots, 70-180 parts of radix paeoniae rubra, 200-450 parts of radix astragali and 200-450 parts of Japanese honeysuckle stems. The Chinese medicine composition for curing the sicca syndrome has the effects of nourishing yin, cooling blood, clearing heat, promoting diuresis, tonifying qi and dredging collaterals, and suitable for curing pain caused by dry eyes, dry mouths, dry skins, dry joints and the like.

The invention relates to a functional health food and in particular relates to a food for changing damp heat constitution and a preparation process thereof. According to reasonable compatibility of medicines, a synergistic effect can be achieved among the effects of the medicines, and the food has the effects of treating symptoms, such as usual dirty and oily complexion, high probability of acne and comedo, red fur and yellow and greasy tongue nature, bitter taste and dry mouth, somatic heaviness and tiredness, annoyance and slacking, eyestring redness, dry or viscous bound stool, scanty dark urine, and high probability of male scrotal moisture and female leukorrhagia, of people with the damp heat constitution.

The present invention relates to a honeysuckle-lotus plumule beverage with functions of heat clearing and pathogenic fire reducing, and a preparation method thereof. The honeysuckle-lotus plumule beverage is prepared from dandelion, lotus plumule, lophatherum gracile, reed rhizome, heartleaf houttuynia herb, honeysuckle, and the like. The honeysuckle-lotus plumule beverage has characteristics of dry mouth and tongue alleviating, excessive heart fire reducing, body fluid regeneration, and fantod removing, and is suitable for people with excessive internal heat.

The invention relates to a medical biological oral liquid, in particular to a medical biological blood sugar level reducing oral liquid and a preparation method thereof. The oral liquid consists of a bitter gourd extracting solution, a rhizoma polygonati extracting solution, a Chinese yam extracting solution, a rhizoma anemarrhenae extracting solution, a radix polygonati officinalis extracting solution, a radix ophiopogonis extracting solution, a radix rehmanniae extracting solution, a radices trichosanthis extracting solution, a fructus lycii extracting solution, a folium mori extracting solution, a radix puerariae extracting solution, a poria with hostwood extracting solution, a liquorice extracting solution, a platycodon grandiflorum extracting solution, a Rhodiola rosea extracting solution, a rhizoma atractylodis macrocephalae extracting solution, a burdock extracting solution, a schisandra chinensis extracting solution and deionized water. All raw materials are mutually matched, advantages are exerted and disadvantages are overcome, the oral liquid is used for treating symptoms such as weakness of the spleen and the stomach, body fatigue and weakness, dry mouth and reduced appetite, deficiency syndrome of the lung and cough caused by dryness, essence and blood deficiency, internal thermal and consumptive thirst. The oral liquid is capable of clearing heat-fire, helping produce saliva and slake thirst, diminishing swelling and discharging pus, and treating pyreticosis, polydipsia, lung heat, dry cough, internal heat and consumptive thirst, and the oral liquid particularly has a good curative effect for treating diabetes and reducing blood glucose.

The invention discloses a novel application of nitrate on an aspect of preventing radiation-induced salivary gland damage, and belongs to the fields of medicine and health. Upon clinical researches and animal experiments, it finally verifies that the nitrate, through oral administration, can be used for effectively preventing the radiation-induced salivary gland damage and for improving the symptom of xerostomia in patients with head and neck tumors due to radiotherapy. The nitrate disclosed by the invention can be used for preparing medicine which is effective on preventing the radiation-induced salivary gland damage; therefore, a novel way is provided for the clinical treatment of radiation-induced xerostomia.

The invention discloses cool mouthwash with anti-inflammatory effect and a preparation method thereof. Traditional Chinese herbs such as Gynura formosana herb, lawn pennywort herb and root of ural licorice are extracted under ultrasonic assistance; extracting concentrating is performed under the temperature of 45-75 DEG C, solid-liquid ratio of 1:25 to 1:35, ultrasonic power of 300-400 W and treatment time of 30-55 min to obtain extract solution; by adding the extract solution to mouthwash, fewer chemically-synthetic effective ingredients are used, and the produced mouthwash is free of sodiumsaccharin, has mild taste, has the effects such as killing bacteria, diminishing inflammation, cooling, detoxifying and removing bad breath, can effectively prevent oral ulcers, gum bleeding and otherconditions, can bring fresh and cool breath, causes zero astringent taste, dryness or burn feeling after consumption, is applicable to babies, people with oral ulcers and people with gum bleeding andis more widely applicable.

The invention discloses a traditional Chinese medicinal composition for treating infantile diarrhea and a preparation method thereof. The composition comprises the following main raw materials: poria, bighead atractylodes rhizome, fried medicated leaven, scorched hawthorn fruit, malt, yam, lotus seed, pomegranate bark, coix seed, dried tangerine peel, fructus amomi, roasted liquorice, chicken gizzard-membrane and powdered sugar. The traditional Chinese medicinal composition can be used for effectively relieving the symptoms of collywobbles, dry mouth and oliguria caused by diarrhea, has an excellent effect of curing diarrhea, has a good effect on treating infantile diarrhea, and is a safe and effective traditional Chinese medicinal composition for treating infantile diarrhea without side effects. Local common medicinal materials are selected for the composition, and the price of the composition is low, so that the economical burden of a patient can be reduced.

An oral composition for the treatment of dry mouth symptoms and other conditions, a method of forming the oral composition, and a method of using the oral composition are disclosed. The oral composition includes a plurality of enzymes to prevent formation of and / or facilitate the break up of biofilm in an oral cavity and a metal ion management system to inhibit growth of gram negative bacteria.

The invention discloses a health-care product lozenge for pharyngitis and a preparation method thereof. The health-care product lozenge for the pharyngitis comprises the following components by weight part: 20 parts of honeysuckle extractives, 20 parts of fructus forsythiae extractives, 20 parts of scaphium scaphigerum extractives, 15 parts of chrysanthemum extractives, 10 parts of tenuifolia extractives, 10 parts of caulis perllae extractives, 15 parts of scutellaria baicalensis extractives, 20 parts of radix scrophulariae extractives, 75 parts of taurine, 68 parts of mannitol, 48 parts of aspartame, 72 parts of menthol and 12 parts of magnesium stearate. The health-care product lozenge for the pharyngitis provided by the invention is a lozenge composed of pure traditional Chinese medicine ingredients, has the effects of nourishing yin and removing heat as well as relieving sore-throat and relieving pain, and is suitable for chronic pharyngitis patients who suffer dry throat, scorching and pain, dry tickle and dumbness, dry mouth and tongue or bucking. Meanwhile, the health-care product lozenge for the pharyngitis tastes good, is convenient to carry and take and is dependency-free. The preparation method for the health-care product lozenge for the pharyngitis provided by the invention is simple and a conventional device can be used for preparing the health-care product lozenge for the pharyngitis.

The present invention provides a composition comprising olive oil, trimethylglycine and xylitol for treating xerostomia and disorders associated thereto, with very good results in increasing the unstimulated salivary flow, in alleviating the symptoms of xerostomia, including the pain associated to xerostomia, as well as improving the quality of life of affected persons. The composition of the invention has also been proved to protect dentin against demineralization in acid conditions.

The invention discloses a compound combination medicament for treating COPD, a preparation method and an application thereof. The compound combination medicament comprises the following components by weight: 10 to 60 parts of codonopsis pilosula, 20 to 50 parts of rhubarb, 40 to 100 parts of root of scutellaria, 15 to 60 parts of lapis chlorite (fried), 10 to 60 parts of bighead atractylodes rhizome (fried), 20 to 60 parts of poria cocos, 10 to 100 parts of pinellia, 5 to 70 parts of reddish orange, 15 to 120 parts of ephedra, 10 to 110 parts of almond, 10 to 150 parts of agilawood, 10 to 60 parts of liguisticum chuanxiong, 5 to 160 parts of ginger, and 40 to 200 parts of earthworm. The compound combination medicament provided in the invention is used for treating the COPD at the attack stage and is mainly used for treating spleen-deficiency and lung-heat COPD, wherein the symptoms of the spleen-deficiency and lung-heat COPD are cough, asthma, expectoration with yellow or white mucous sputum, dry excrement, dry mouth, abdominal fullness and distension, flat tongue with tooth mark on it, thin and yellow tongue coating, and wiry and slippery pulse. The compound combination medicament provided in the invention is used for treating the COPD at the attack stage and is mainly used for treating spleen-deficiency and lung-heat COPD, wherein the symptoms of the spleen-deficiency and lung-heat COPD are cough, asthma, expectoration with yellow or white mucous sputum, dry excrement, dry mouth, abdominal fullness and distension, flat tongue with tooth mark on it, thin and yellow tongue coating, and wiry and slippery pulse. The compound combination medicament has advantages of good curative effectiveness, short treating course, thorough treatment, no side effects and the like. Moreover, the compound combination medicament, which is made in a form of mixture, tablet, capsule, pellet, is easy to carry and to take.

The invention provides a caulis fici tikouae-coriander root health beverage and a preparation method thereof. The caulis fici tikouae-coriander root health beverage utilizes caulis fici tikouae and coriander root as main materials and also utilizes cape jasmine flower, chrysanthemum, wolfberry, mustard seed, beet leaf and a multi-vitamin nutrition additive as accessory materials. The caulis fici tikouae has effects of clearing heat, disinhibiting dampness, invigorating the circulation of blood and removing toxins. The coriander root has effects of resisting viruses and preventing cold. The main materials are combined with the accessory materials such as the cape jasmine flower, chrysanthemum, wolfberry, mustard seed, beet leaf and multi-vitamin nutrition additive. The formula of the caulis fici tikouae-coriander root health beverage has strict composition, is terse and concise, is all natural and utilizes the harmless raw materials. The caulis fici tikouae-coriander root health beverage is suitable for being drunk by people having symptoms of large endogenous fire and dry mouth.