82 results about "Dry mouth" patented technology

According to the novel mandibular protraction appliance and the digitization-based manufacturing method thereof, a vestibular shield is arranged on the lip side of the lower anterior teeth of the mandibular protraction appliance, and the appliance can effectively seal the oral cavity and improve the dry mouth symptom possibly occurring when a traditional mandibular protraction appliance is worn; the common mouth breathing problem of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) is solved, and the limitation of lip inclination of lower anterior teeth caused by a traditional mandibular advancement appliance is reduced more remarkably.

The invention provides a traditional Chinese medicine compound for treating sicca syndrome and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compounds. The traditional Chinese medicine compound provided by the invention has the effects of eliminating dampness and heat, removing blood stasis and promoting salivation, can safely and effectively treat sicca syndrome by improving functions of exocrine glands and regulating immunity, belongs to a pure traditional Chinese medicine preparation, and has no toxic or side effect. The traditional Chinese medicine compound is proved to be capable of remarkably relieving the sicca syndrome, relieving dry mouth and eye symptoms of a patient, relieving fatigue, regulating and controlling a plurality of signals taking RAGE / TLR4 as a core, inhibiting excessive activation of an HMGB1-RAGE / TLR4-NF-kappa B pro-inflammatory pathway from gene and protein levels, inhibiting generation of pro-inflammatory cytokines, reducing inflammatory response and improving the immunity of the patient. The effect of treating the sicca syndrome is achieved. By acting on STAT3 phosphorylation, Tfh proliferation is inhibited, IL-21 secretion is reduced, humoral immune disorder is relieved, and the sicca syndrome is treated, so that the condition of the sicca syndrome is relieved, and the prognosis of the sicca syndrome is improved.

The present application discloses a device for caring for dry mouth of anesthetized patients, belonging to the field of fluid conveying devices for human body, comprising a water storage module, a water delivery module and an elastic pouch, wherein the inlet end of the water delivery module is connected to the water storage module, and the outlet end of the water delivery module is connected to a temporary storage tube; a water storage sheet is arranged in the elastic pouch, and a plurality of water seepage holes are arranged on the outer surface of the elastic pouch; the elastic pouch and the temporary storage tube are connected via a connecting tube, and the connecting tube is filled with a water diversion cotton swab, and along the axis of the connecting tube, one end of the water diversion cotton swab is inserted into the temporary storage tube, and the other end thereof is tightly fitted with the water storage sheet; the present application uses the water diversion cotton swab and the water delivery module to make the water content of the water storage sheet located in the patient's oral cavity always in an oversaturated state, thereby controlling water to continuously enter the patient's oral cavity in the form of droplets, and realizing continuous water delivery while controlling the water delivery amount, which not only simplifies the nursing procedure for the patient's dry mouth, but also can moisten the patient's oral cavity for a long time, thereby improving the quality of dry mouth care for anesthetized patients.

The invention discloses a quantitative evaluation method for the dry mouth degree of a wine product after drinking, which comprises the following steps: step 1, tested mice are divided into a control group and a test group, the mice in the control group do not ingest alcohol, the test group performs single gavage on wine products with different dry mouth degrees, and the total amount of alcohol in the single gavage on the wine products of the mice in the test group is the same; and step 2, at different time points, detecting the change conditions of the mouth dryness biochemical index contents of the mice in the control group and the test group, scoring the mouth dryness degree, and evaluating the mouth dryness degree of the corresponding wine body drunk by the mice according to the score. The method has the advantages of being easy and convenient to operate, high in sensitivity, high in practicability and the like, subjective evaluation can be conducted on the dry mouth effect of the wine sample instead of a crowd test, damage to the human body is reduced, the evaluation result is more objective, an evaluation system for the comfort degree of the wine after drinking is widened, and a new evaluation method is provided for further researching and improving the comfort degree of the wine product after drinking.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a kidney-tonifying and liver-nourishing compound preparation and a preparation method thereof. The compound preparation comprises 5-15 parts of roasted herba epimedii, 5-15 parts of fructus cnidii, 50-70 parts of roasted radix astragali and 10-30 parts of pulp of dogwood fruit. The traditional Chinese medicine composition has remarkable curative effects on various diseases and chronic strain caused by deficiency of liver and kidney and deficiency of blood and essence, such as dizziness, blurred vision, fatigue, swelling and pain of waist, back and limbs, dry mouth and eyes, limb ache and weakness, irregular menstruation, incapability of holding weight or hemiplegia and the like, and has a very good application prospect.

This invention discloses a traditional Chinese medicine composition for improving fever in wind-heat common cold, belonging to the field of traditional Chinese medicine preparation technology. Addressing the shortcomings of existing Western medicines that suppress fever through central nervous system suppression, easily damaging organs and inhibiting microcirculation, and the limitations of traditional Chinese medicine preparations such as bitter and cold properties that astringe pathogens, causing low-grade fever rebound, damaging yin and spleen, and insufficient ability to resolve phlegm and strengthen the body, this invention innovatively combines the principles of monarch, minister, assistant, and guide herbs in a synergistic formulation based on the core microscopic pathogenesis of wind-heat common cold: "constriction of visceral microvessels, stagnation of heat pathogens, high fever depleting body fluids, fluid deficiency and blood stasis, and phlegm production due to stagnation." This invention is prepared using gardenia, platycodon, angelica, peppermint, ophiopogon, dandelion, lily, coix seed, and rehmannia as core raw materials. It utilizes pungent and dispersing herbs to open up the microcirculation of the body surface and lungs, dispersing stagnant heat and replacing the traditional bitter and cold heat-suppressing mechanism. Combined with heat-clearing and anti-inflammatory components, it targets and inhibits the release of inflammatory factors, resulting in stable fever reduction. Small doses of yin-nourishing herbs repair the damage to body fluids and blood caused by high fever, reversing the pathology of fluid deficiency and blood stasis. Spleen-strengthening and dampness-removing herbs harmonize the medicinal properties and strengthen the spleen. This invention achieves a balance of hot and cold properties, and addresses both tonification and purgation, providing a one-stop solution for complex symptoms such as fever, sore throat, nasal congestion, yellow phlegm, dry mouth, weakness, and fatigue caused by dampness in wind-heat colds. It provides stable fever reduction without rebound, and avoids the side effects of Western medicine and bitter and cold Chinese patent medicines. It addresses both the symptoms and the root cause, effectively avoiding post-cold sequelae and reducing the recurrence rate. Furthermore, the preparation process is simple, allowing for processing into various dosage forms, suitable for industrial mass production and widespread clinical application, possessing extremely high medical value and market potential.

The invention discloses a traditional Chinese medicine compound composition with an effect of preventing and treating radioactive injury as well as a preparation method and application thereof. The traditional Chinese medicine compound composition is prepared from 5-15 parts of American ginseng, 3-6 parts of sea-buckthorn and 10-30 parts of rhizoma polygonati. The composition is proportioned and optimized according to the theory of treatment based on syndrome differentiation, and the medicines are combined to achieve the effects of tonifying qi, activating blood and nourishing yin. Clinical experiment results show that the traditional Chinese medicine compound composition provided by the invention has a remarkable effect of preventing and treating radioactive injury, particularly has a remarkable curative effect in the aspects of improving oral mucositis, dry mouth, weakness, sleep disorder and the like after radiotherapy, and is safe in clinical medication.

The invention belongs to the technical field of nicotine compositions, and particularly relates to a nicotine solid atomized preparation with throat-clearing and sore-throat-relieving effects. According to the preparation, the throat-clearing and sore-throat-relieving functional components are added and are controlled to be mainly deposited at the oropharynx, so that the nicotine is delivered, and meanwhile, the symptoms such as oral pharyngitis and dry mouth caused by electronic cigarette smoking are relieved. When the preparation is used, phase change is avoided, nicotine atomization can be achieved at normal temperature or low temperature (smaller than or equal to 60 DEG C), the conditions of ketone substances, metal leaching and the like cannot be generated, and meanwhile electronic waste cannot be generated; the nicotine component is micronized, second-hand smoke exposure is reduced, the nicotine component is solid aerosol, granular sensation of the throat of the tobacco is reduced, throat hitting sensation closer to that of the cigarette is generated, and therefore the better effect of replacing the cigarette can be achieved, and the conversion rate of replacing the cigarette is increased. In addition, a solid formula is adopted, transportation and carrying are convenient, and the problems of liquid leakage during transportation, liquid leakage during shelving, non-lasting fragrance retention and the like do not exist.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a ginseng and licorice root formula for treating renal hematuria, its preparation method, and its application. The ginseng and licorice root formula for treating renal hematuria of this invention comprises the following raw materials in parts by weight: 5-15 parts of Codonopsis pilosula, 15-30 parts of Rehmannia glutinosa, 5-15 parts of Ligustrum lucidum, 5-15 parts of Eclipta prostrata, 5-15 parts of Imperata cylindrica, 5-15 parts of Rubia cordifolia, 5-15 parts of Cirsium japonicum, 5-15 parts of Taraxacum mongolicum, 5-8 parts of Prunus persica, and 3-5 parts of Glycyrrhiza uralensis. Clinical trials have shown that the ginseng and licorice root formula for treating renal hematuria of this invention not only reduces urinary red blood cells but also improves traditional Chinese medicine clinical symptoms such as lower back and knee weakness, fixed or stabbing lower back pain, pale complexion, fatigue, dry mouth, bitter taste, sore throat, rough skin, and poor appetite. It has good therapeutic effects, reliable safety, and can significantly improve the treatment efficacy of chronic nephritis syndrome.

A formulation for treating and alleviating xerostomia is provided. Formulations comprising a humectant (e.g., propylene glycol), a chelating agent (e.g., EDTA and salts thereof), and a transport promoter (e.g., methylsulfonylmethane (MSM)) are provided.

The invention belongs to the technical field of traditional Chinese medicines, and mainly relates to a traditional Chinese medicine composition for clearing heat from throat, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: 0.9 to 1.5 parts by weight of radix scrophulariae, 1.2 to 5.0 parts by weight of radix polygonati officinalis, 1.0 to 3.0 parts by weight of radix glehniae, 1.0 to 1.5 parts by weight of radix rehmanniae, 1.0 to 3.0 parts by weight of radix ophiopogonis, 1.5 to 6.0 parts by weight of gypsum and 0.5 to 3.0 parts by weight of liquorice root. The preparation method of the traditional Chinese medicine preparation comprises the working procedures of processing, burdening, extracting, concentrating, preparing a soft material, granulating, drying and finishing granules. The traditional Chinese medicine composition or the traditional Chinese medicine preparation for clearing heat from throat can relieve symptoms such as red and swollen pharynx, dry mouth and dry throat, pharyngalgia, pharynx itching, scorching fever, less phlegm and foreign body sensation of pharynx caused by heat evil, and has a remarkable curative effect on chronic pharyngitis. Through a unified preparation method, the accuracy of the quality and dosage of the used medicinal materials and the stability of the treatment effect are ensured.

The invention discloses dendrobium herbal tea and a preparation method thereof, and belongs to the technical field of medicine and food processing.The dendrobium herbal tea is prepared from 3-4 parts of dendrobium officinale, 2-3 parts of radix puerariae, 2-3 parts of rhizoma polygonati, 1-2 parts of chrysanthemum, 1-2 parts of honeysuckle, 3-4 parts of poria cocos, 3-4 parts of semen coicis and 1-2 parts of liquorice through the processes of extraction, filtration, refining, concentration, blending, filling, sterilization and the like. The herba dendrobii herbal tea provided by the invention is formulated according to the theory of traditional Chinese medicine, can help people with fire excess from yin deficiency to improve the conditions of yin impairment and body fluid deficiency, dry mouth and polydipsia, deficiency-heat after illness and the like by nourishing yin, clearing heat, invigorating spleen and excreting dampness, does not cause diarrhea, stomachache and other uncomfortable symptoms caused by spleen and stomach function decline, and is especially suitable for body fluid insufficiency, yin deficiency and internal heat caused by diabetes mellitus.

The utility model discloses a drinking water aerosol inhalation device for radiotherapy patient nursing, which comprises a device main body, a water storage tank, an atomizing cup, an ultrasonic atomizing sheet and a heater, the water storage tank is fixed on one side of the surface of the device main body, the atomizing cup is arranged in the device main body, the ultrasonic atomizing sheet is arranged at the bottom of the atomizing cup, and the heater is arranged on the atomizing cup. The heater is installed in the atomizing cup, heating wires are installed in the heater at equal intervals, a fan is installed at the top of the atomizing cup, a water pump is installed on one side of the bottom of the device body, a corrugated hose is arranged above the device body, and a mouthpiece is arranged at the bottom end of the corrugated hose. The mouth piece not only has a good moistening effect on the oral cavity and can effectively relieve the symptom of dry mouth of a radiotherapy patient, so that water mist inhaled by the patient is kept at a proper temperature, but also is convenient to fix the mouth piece in the mouth, the tightness of the ear hanging rope is adjustable, and the mouth piece is labor-saving and convenient.

The invention discloses a radioactive xerostomia depth prediction system based on multi-source channel fusion, and relates to the technical field of image processing, and the system comprises a preprocessing module which is used for obtaining a CT image, a Dose distribution image, GTV and parotid gland structure data and corresponding follow-up visit information before radiotherapy of a head and neck cancer case, carrying out data preprocessing, and dividing a data set; the multi-source data fusion module is divided into a 3D Multi-GTVCNN model and a 3D Multi-PACNN model which are respectively used for fusing CT, Dose and GTV data of any size and CT, Dose and parotid gland data of the same size; the decision fusion module is used for fusing prediction results of the two multi-source data modules; and the prediction module is used for predicting the xerostomia. According to the method, the GTV contour is innovatively introduced as input, the models are trained according to different data characteristics, and the prediction performance is improved through decision fusion, so that the models can extract richer characteristics, the error-tolerant rate is increased, and the accuracy and stability of radioactive xerostomia prediction are improved.

The invention discloses a formula and a preparation method of a disease-preventing health-care oral liquid. The health-care food is prepared from the following raw materials in parts by weight: 4 to 6 milliliters of purple perilla seed oil, 5 to 7 milliliters of walnut oil, 100 to 150 milligrams of algal oil, 200 to 250 milligrams of grape seed extract, 50 to 80 milligrams of selenium-enriched yeast, 80 to 120 milligrams of vitamin C, 80 to 120 milligrams of vitamin E, 0.6 to 1.0 milligram of vitamin B1 (thiamine) and 0.6 to 1.0 milligram of vitamin B2 (riboflavin). After being taken by multiple persons for a period of time, the traditional Chinese medicine composition is proved to be safe to take, free of adverse reaction and obvious in health care effect, old people feel weak in action, heavy in whole body, dry in mouth and throat and insomnia and constipation before taking the traditional Chinese medicine composition, symptoms are relieved after taking the traditional Chinese medicine composition, and the traditional Chinese medicine composition is safe to take, free of adverse reaction and obvious in health care effect. Young people are good in working state and honor in spirit, and children are fast in learning progress, good in taste, high in adaptability and beneficial to popularization, and can play a positive role in prevention before illness.

The invention discloses an application of bead exosome-like nano-vesicles in treatment of Sjogren's syndrome. The bead exosome-like nano-vesicle is prepared through a differential centrifugation method and an ultracentrifugation method, and toxicological evaluation shows that the bead exosome-like nano-vesicle has good safety and can be used for in-vivo and in-vitro treatment. In-vivo experiments prove that the Sjogren's syndrome model mouse treated by the bead exosome-like nano-vesicles has significantly increased salivary secretion and significantly improved dry mouth symptom; in-vitro experiments further show that the nano vesicles can also significantly improve the activity and the water secretion function of salivary gland epithelial cells in the Sjogren's syndrome. The exosome-like nano-vesicles are successfully extracted from bead leaves and are creatively used for treating the Sjogren's syndrome, and a brand new thought and a material source are provided for research and development of medicines for treating the Sjogren's syndrome.

The invention belongs to the technical field of heating tobacco products, and provides an aerosol generating substrate and a preparation method thereof, an aerosol generating product, the aerosol generating substrate comprises a tobacco material, an aerosol forming agent and a taste improving agent, the taste improving agent comprises a calcium phosphate compound or a composition of the calcium phosphate compound and an oxide, and the taste improving agent comprises a calcium phosphate compound or a composition of the calcium phosphate compound and the oxide. The molar ratio of the calcium element to the phosphorus element in the taste improver is 1.1-2.0. The mouth feel improver is basically stable in processing or using environments such as high temperature and the like, does not release unpleasant substances and other substances without obvious sense organ positive promotion, has the capability of mildly improving acidic mouth feel, and does not generate mouth dryness.

The invention discloses artificial saliva and a preparation method of artificial saliva hydrogel. The artificial saliva is prepared from the following raw materials in parts by mass: 0.5 to 1 g of KCl, 0.2 to 0.4 g of K2HPO4, 0.2 to 0.8 g of NaCl, 0.2 to 0.4 g of KH2P O4, 10.04 to 20.8 g of CaCl2, 1.5 to 3 g of Nacaboxymethlecellulose, 60 to 120 mg of brown moss alcohol, 495 to 1000 ml of natural coconut juice and 5 to 10 ml of herba sarcandrae extract. By selecting the glabrous sarcandra herb extract, anti-inflammatory and anti-tumor treatment is realized, so that the traditional Chinese medicine composition has a remarkable effect on dry mouth caused by radiotherapy; through the form of a gel bead preparation, the beverage is more portable and unique in taste. The gel beads serve as one of oral local administration preparations, and after the gel beads are exploded, drugs can target small glands which are located below oral mucosa and secrete saliva, and the rapid drug effect is achieved. Direct local administration to the oral mucosa may provide rapid drug action, activate small salivary glands within the buccal mucosa, while avoiding systemic drug exposure and off-target effect.

Kit and method for treating patients with dry mouth syndrome. The kit includes a dental mouthpiece with one or more near-infrared light sources. Once placed in the oral cavity, it directs the light toward the selected target tissue (salivary glands, submandibular glands, or both) for the treatment of patients with dry mouth syndrome. The kit and method can be used to treat Sjögren's syndrome, patients taking multiple medications, diabetic patients, or patients with a reduced number of salivary glands, resulting in a marked, temporary, or permanent decrease in saliva production.

The present invention belongs to the technical field of traditional Chinese medicine, and mainly relates to a traditional Chinese medicine composition for clearing the throat and relieving sore throat, a traditional Chinese medicine preparation, and their preparation methods and applications. The traditional Chinese medicine composition is composed of the following traditional Chinese medicines in parts by weight: 0.9-1.5 parts by weight of Scrophulariae Radix, 1.2-5.0 parts by weight of Polygonati Odorati Rhizoma, 1.0-3.0 parts by weight of Glehniae Radix, 1.0-1.5 parts by weight of Rehmanniae Radix, 1.0-3.0 parts by weight of Ophiopogonis Radix, 1.5-6.0 parts by weight of Gypsum Fibrosum, and 0.5-3.0 parts by weight of Glycyrrhizae Radix. The preparation method of the traditional Chinese medicine preparation includes processes of processing, proportioning, extraction, concentration, soft material preparation, granulation, drying, and sizing. The traditional Chinese medicine composition or preparation for clearing the throat and relieving sore throat can relieve symptoms such as red and swollen pharynx, dry mouth and throat, sore throat, itchy throat, burning sensation, less phlegm, and foreign body sensation in the pharynx caused by pathogenic heat, and shows significant curative effect on the treatment of chronic pharyngitis. Through a unified preparation method, the quality and dosage accuracy of the medicinal materials used are ensured, as well as the stability of the treatment effect.

The application discloses a traditional Chinese medicine compound for treating Sjogren's syndrome and a preparation method and application thereof. The traditional Chinese medicine compound is prepared from Huangqi, Danshen, Maidong and Dendrobium officinale. The traditional Chinese medicine for treating Sjogren's syndrome has the functions of tonifying qi, generating fluid, nourishing yin, moistening dryness, promoting blood circulation and removing blood stasis. The traditional Chinese medicine for treating Sjogren's syndrome has unique advantages, can obviously improve the dry mouth, anti-fatigue, submandibular gland lymphocyte infiltration and T cell subpopulation proportion disorder of Sjogren's syndrome, and is an effective pure traditional Chinese medicine preparation.

A mouthpiece device and method for helping human users with congested sinuses breathe freely through their mouths while sleeping while minimizing the risks of dry mouth and drooling. The device fits between the user's jaws and is configured to apply a gentle jaw and lip opening pressure sufficient to at least partially open a sleeping user's jaw and lips while the jaw and lip muscles are relaxed. At the same time, the device is configured to so that when the user, while still sleeping, activates their jaw or lip muscles to swallow, this action overcomes the gentle opening force, allowing the user to easily swallow without conscious effort. Methods of configuring the device shape and opening forces are also taught. These include using implanted sensors, processors, and actuators configured to optimize the opening forces according to user physiology; and / or wireless connection to external sensing and control devices.

The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for relieving muscles and penetrating rashes, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5-30 parts of pachouli, 10-40 parts of kudzu vine, 5-30 parts of notopterygium, 10-40 parts of talc, 5-30 parts of red peony root, 5-30 parts of thin soja bean, 5-30 parts of lophatherum gracile, 5-30 parts of raw rehmannia, and 10-30 parts of forsythia. The traditional Chinese medicine composition has the effects of dispelling dampness and relieving muscles, clearing heat and penetrating rashes, and can effectively improve the symptoms of fever, arthralgia, rash, fatigue, dry mouth and bitter taste, thick and greasy tongue fur and the like of patients with chikungunya fever caused by dampness stagnation in muscles and joints and heat entering the interior.

The present invention belongs to the technical field of edible and medicinal compositions, and specifically relates to an edible and medicinal composition for assisting in regulating blood sugar, and its preparation method, application, and preparation. The edible and medicinal composition is composed of mulberry leaves, black sesame seeds, polygonatum, and yam. Animal experiments of the present invention show that only four edible and medicinal substances, namely mulberry leaves, black sesame seeds, polygonatum, and yam, as the edible and medicinal composition can have a good hypoglycemic effect. Compared with the prior art, the composition of the present invention has simple components, reasonable compatibility, low cost, small dosage, and fast short-term hypoglycemic effect. The edible and medicinal composition of the present invention not only has a significant effect on lowering blood sugar after meals, but also has a significant effect on improving complications such as dry mouth and thirst that are common in "Qi and Yin deficiency type" diabetes. Its raw materials are natural and harmless, highly safe, and the overall nature and taste are sweet and flat, making it suitable for long-term use.

The utility model discloses a water feeder for relieving mouth dryness of a stomach tube patient. Comprising a water supply bottle and a clamping device, and the clamping device is used for clamping the water supply bottle; the water supply bottle comprises a water storage bottle and a telescopic suction nozzle, and the telescopic suction nozzle is installed on the water storage bottle; wherein the telescopic suction nozzle comprises a suction nozzle, a telescopic suction pipe and a shaping pipe, one end of the telescopic suction pipe is connected with the suction nozzle, and the shaping pipe is arranged on the periphery of the telescopic suction pipe in a sleeving mode and connected with the suction nozzle; and when the telescopic suction tube is elongated or shortened, the shaping tube and the telescopic suction tube are elongated or shortened, and the suction nozzle is elongated or shortened along the axis of the telescopic suction tube. The water supply bottle is clamped by one end of the clamping device, and the other end of the clamping device is fixed on the nursing bed, so that the water supply bottle can be conveniently adjusted to be close to the head of a patient; the length of the telescopic suction nozzle is adjusted, and the telescopic suction pipe and the shaping pipe are stretched or compressed, so that the suction nozzle extends to the mouth of the patient, the patient can suck drinking water only by slightly rotating the head, and the working efficiency of medical staff is improved.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition for clearing heat and relieving irritability, its preparation method, and its application. The traditional Chinese medicine composition of this invention, by weight, comprises the following raw materials: 5-30 parts Asparagus root, 2-15 parts Chrysanthemum, 5-10 parts Imperata root, 2-5 parts Rose, 3-10 parts Lophatherum leaf, and 3-6 parts Tangerine peel. This traditional Chinese medicine composition for clearing heat and relieving irritability has the effects of clearing and moistening heart fire, relieving depression and irritability, calming the mind and aiding sleep. Clinical studies have shown that this traditional Chinese medicine composition for clearing heat and relieving irritability can effectively improve symptoms such as insomnia, excessive dreaming, palpitations, irritability, dry mouth, bitter taste, oral ulcers, and hypochondriac distension caused by liver qi stagnation and its transformation into fire disturbing the heart.

The invention discloses a traditional Chinese medicine heart nourishing and nerve soothing formula for treating insomnia. The formula is composed of spina date seed, mulberry, dendrobium, trichosanthes peel, cassia seed, dark plum, poria with hostwood and green plum blossom. The heart-nourishing and mind-tranquilizing formula is mainly used for nourishing the heart, tranquilizing the mind, nourishing yin, clearing heat, soothing the liver and relieving depression, and spina date seeds and poria with hostwood in the formula are used as monarch materials to nourish heart yin, tranquilize the mind, stabilize the mind and Mulberry, dendrobium and dark plum are used as ministerial drugs to nourish yin, promote salivation, clear deficiency heat and improve dysphoria, night sweat and dry mouth caused by fire excess from yin deficiency. The semen cassiae has the effects of clearing liver fire and relaxing bowel, and the semen cassiae and the semen cassiae can assist in clearing away the heart-fire and reducing phlegm; the green plum blossom can soothe liver depression without hurting yin, and is capable of soothing liver, harmonizing stomach and regulating qi. The prescription is used for overall conditioning of complex pathogenesis (yin deficiency, liver depression and phlegm heat) of insomnia, and is especially suitable for people with insomnia caused by high pressure, unsmooth emotion and staying up late at present. Compatible medication has local characteristics of new-safety medicine, is particularly beneficial to improvement of insomnia symptoms and the like, and is definite in curative effect and free of toxic and side effects.

A mouthpiece device and method for helping human users with congested sinuses breathe freely through their mouths while sleeping while minimizing the risks of dry mouth and drooling. The device fits between the user's jaws and is configured to apply a gentle jaw and lip opening pressure sufficient to at least partially open a sleeping user's jaw and lips while the jaw and lip muscles are relaxed. At the same time, the device is configured to so that when the user, while still sleeping, activates their jaw or lip muscles to swallow, this action overcomes the gentle opening force, allowing the user to easily swallow without conscious effort. Methods of configuring the device shape and opening forces are also taught. These include using implanted sensors, processors, and actuators configured to optimize the opening forces according to user physiology; and / or wireless connection to external sensing and control devices.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for dispelling wind and moistening dryness as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5 to 20 parts of folium mori, 5 to 15 parts of semen armeniacae amarae, 5 to 25 parts of bulbus fritillariae thunbergii, 5 to 25 parts of radix glehniae, 5 to 25 parts of radix ophiopogonis, 10 to 30 parts of rhizoma phragmitis, 10 to 20 parts of radix peucedani, 5 to 20 parts of herba menthae and 3 to 15 parts of liquorice root. The traditional Chinese medicine composition disclosed by the invention has the effects of dispelling wind, moistening dryness and clearing lung, can effectively relieve cough, throat itching and dry throat, dry lip and nose, no phlegm or less and sticky phlegm and difficulty in cough, or accompanied with dry mouth, pharyngalgia, body fever, headache, red and dry tongue with less saliva, thin white or thin yellow coating and floating pulse of a patient suffering from the flu wind-dryness syndrome, and can be used for treating the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu. The traditional Chinese medicine has a good treatment effect on influenza wind-dryness syndrome.

This invention belongs to the field of traditional Chinese medicine preparation technology, specifically relating to a traditional Chinese medicine composition for treating dry mouth in Sjögren's syndrome and its preparation method. The traditional Chinese medicine composition includes the following raw materials in parts by weight: 10g Rehmannia glutinosa, 9g Scrophularia ningpoensis, 10g Ophiopogon japonicus, 10g Fagopyrum dibotrys, 10g Phragmites communis, 6g Amomum villosum, and 3g Bletilla striata. Depending on clinical diagnosis, other herbs such as Cornus officinalis, Trichosanthes kirilowii, Lophatherum gracile, Paeonia suffruticosa, and Poria cocos may be selectively added. The preparation method includes two decoctions, filtration, and combining the filtrates. It is derived from the Kidney-Nourishing, Heat-Clearing, and Yin-Nourishing Decoction, retaining the core of the Fluid-Increasing Decoction, and adding three lung / stomach meridian-invigorating herbs: Fagopyrum dibotrys, Phragmites communis, and Bletilla striata. The core treatment principle is to nourish yin and generate fluids, clear heat and remove blood stasis, promote tissue regeneration and wound healing, and harmonize the spleen and stomach. Clinical observation shows that it can significantly reduce the VAS score for dry mouth in patients with Sjögren's syndrome, increase static salivary flow rate, and promote the recovery of oral mucosal ulcers and angular cheilitis. It has good safety and can be taken orally for overall conditioning or used as a mouthwash to directly target the affected area.