64 results about "Dry mouth" patented technology

The invention discloses a quantitative evaluation method for the dry mouth degree of a wine product after drinking, which comprises the following steps: step 1, tested mice are divided into a control group and a test group, the mice in the control group do not ingest alcohol, the test group performs single gavage on wine products with different dry mouth degrees, and the total amount of alcohol in the single gavage on the wine products of the mice in the test group is the same; and step 2, at different time points, detecting the change conditions of the mouth dryness biochemical index contents of the mice in the control group and the test group, scoring the mouth dryness degree, and evaluating the mouth dryness degree of the corresponding wine body drunk by the mice according to the score. The method has the advantages of being easy and convenient to operate, high in sensitivity, high in practicability and the like, subjective evaluation can be conducted on the dry mouth effect of the wine sample instead of a crowd test, damage to the human body is reduced, the evaluation result is more objective, an evaluation system for the comfort degree of the wine after drinking is widened, and a new evaluation method is provided for further researching and improving the comfort degree of the wine product after drinking.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a kidney-tonifying and liver-nourishing compound preparation and a preparation method thereof. The compound preparation comprises 5-15 parts of roasted herba epimedii, 5-15 parts of fructus cnidii, 50-70 parts of roasted radix astragali and 10-30 parts of pulp of dogwood fruit. The traditional Chinese medicine composition has remarkable curative effects on various diseases and chronic strain caused by deficiency of liver and kidney and deficiency of blood and essence, such as dizziness, blurred vision, fatigue, swelling and pain of waist, back and limbs, dry mouth and eyes, limb ache and weakness, irregular menstruation, incapability of holding weight or hemiplegia and the like, and has a very good application prospect.

This invention discloses a traditional Chinese medicine composition for improving fever in wind-heat common cold, belonging to the field of traditional Chinese medicine preparation technology. Addressing the shortcomings of existing Western medicines that suppress fever through central nervous system suppression, easily damaging organs and inhibiting microcirculation, and the limitations of traditional Chinese medicine preparations such as bitter and cold properties that astringe pathogens, causing low-grade fever rebound, damaging yin and spleen, and insufficient ability to resolve phlegm and strengthen the body, this invention innovatively combines the principles of monarch, minister, assistant, and guide herbs in a synergistic formulation based on the core microscopic pathogenesis of wind-heat common cold: "constriction of visceral microvessels, stagnation of heat pathogens, high fever depleting body fluids, fluid deficiency and blood stasis, and phlegm production due to stagnation." This invention is prepared using gardenia, platycodon, angelica, peppermint, ophiopogon, dandelion, lily, coix seed, and rehmannia as core raw materials. It utilizes pungent and dispersing herbs to open up the microcirculation of the body surface and lungs, dispersing stagnant heat and replacing the traditional bitter and cold heat-suppressing mechanism. Combined with heat-clearing and anti-inflammatory components, it targets and inhibits the release of inflammatory factors, resulting in stable fever reduction. Small doses of yin-nourishing herbs repair the damage to body fluids and blood caused by high fever, reversing the pathology of fluid deficiency and blood stasis. Spleen-strengthening and dampness-removing herbs harmonize the medicinal properties and strengthen the spleen. This invention achieves a balance of hot and cold properties, and addresses both tonification and purgation, providing a one-stop solution for complex symptoms such as fever, sore throat, nasal congestion, yellow phlegm, dry mouth, weakness, and fatigue caused by dampness in wind-heat colds. It provides stable fever reduction without rebound, and avoids the side effects of Western medicine and bitter and cold Chinese patent medicines. It addresses both the symptoms and the root cause, effectively avoiding post-cold sequelae and reducing the recurrence rate. Furthermore, the preparation process is simple, allowing for processing into various dosage forms, suitable for industrial mass production and widespread clinical application, possessing extremely high medical value and market potential.

The invention discloses a traditional Chinese medicine compound composition with an effect of preventing and treating radioactive injury as well as a preparation method and application thereof. The traditional Chinese medicine compound composition is prepared from 5-15 parts of American ginseng, 3-6 parts of sea-buckthorn and 10-30 parts of rhizoma polygonati. The composition is proportioned and optimized according to the theory of treatment based on syndrome differentiation, and the medicines are combined to achieve the effects of tonifying qi, activating blood and nourishing yin. Clinical experiment results show that the traditional Chinese medicine compound composition provided by the invention has a remarkable effect of preventing and treating radioactive injury, particularly has a remarkable curative effect in the aspects of improving oral mucositis, dry mouth, weakness, sleep disorder and the like after radiotherapy, and is safe in clinical medication.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a ginseng and licorice root formula for treating renal hematuria, its preparation method, and its application. The ginseng and licorice root formula for treating renal hematuria of this invention comprises the following raw materials in parts by weight: 5-15 parts of Codonopsis pilosula, 15-30 parts of Rehmannia glutinosa, 5-15 parts of Ligustrum lucidum, 5-15 parts of Eclipta prostrata, 5-15 parts of Imperata cylindrica, 5-15 parts of Rubia cordifolia, 5-15 parts of Cirsium japonicum, 5-15 parts of Taraxacum mongolicum, 5-8 parts of Prunus persica, and 3-5 parts of Glycyrrhiza uralensis. Clinical trials have shown that the ginseng and licorice root formula for treating renal hematuria of this invention not only reduces urinary red blood cells but also improves traditional Chinese medicine clinical symptoms such as lower back and knee weakness, fixed or stabbing lower back pain, pale complexion, fatigue, dry mouth, bitter taste, sore throat, rough skin, and poor appetite. It has good therapeutic effects, reliable safety, and can significantly improve the treatment efficacy of chronic nephritis syndrome.

The invention belongs to the technical field of traditional Chinese medicines, and mainly relates to a traditional Chinese medicine composition for clearing heat from throat, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: 0.9 to 1.5 parts by weight of radix scrophulariae, 1.2 to 5.0 parts by weight of radix polygonati officinalis, 1.0 to 3.0 parts by weight of radix glehniae, 1.0 to 1.5 parts by weight of radix rehmanniae, 1.0 to 3.0 parts by weight of radix ophiopogonis, 1.5 to 6.0 parts by weight of gypsum and 0.5 to 3.0 parts by weight of liquorice root. The preparation method of the traditional Chinese medicine preparation comprises the working procedures of processing, burdening, extracting, concentrating, preparing a soft material, granulating, drying and finishing granules. The traditional Chinese medicine composition or the traditional Chinese medicine preparation for clearing heat from throat can relieve symptoms such as red and swollen pharynx, dry mouth and dry throat, pharyngalgia, pharynx itching, scorching fever, less phlegm and foreign body sensation of pharynx caused by heat evil, and has a remarkable curative effect on chronic pharyngitis. Through a unified preparation method, the accuracy of the quality and dosage of the used medicinal materials and the stability of the treatment effect are ensured.

The invention discloses a radioactive xerostomia depth prediction system based on multi-source channel fusion, and relates to the technical field of image processing, and the system comprises a preprocessing module which is used for obtaining a CT image, a Dose distribution image, GTV and parotid gland structure data and corresponding follow-up visit information before radiotherapy of a head and neck cancer case, carrying out data preprocessing, and dividing a data set; the multi-source data fusion module is divided into a 3D Multi-GTVCNN model and a 3D Multi-PACNN model which are respectively used for fusing CT, Dose and GTV data of any size and CT, Dose and parotid gland data of the same size; the decision fusion module is used for fusing prediction results of the two multi-source data modules; and the prediction module is used for predicting the xerostomia. According to the method, the GTV contour is innovatively introduced as input, the models are trained according to different data characteristics, and the prediction performance is improved through decision fusion, so that the models can extract richer characteristics, the error-tolerant rate is increased, and the accuracy and stability of radioactive xerostomia prediction are improved.

The invention discloses a formula and a preparation method of a disease-preventing health-care oral liquid. The health-care food is prepared from the following raw materials in parts by weight: 4 to 6 milliliters of purple perilla seed oil, 5 to 7 milliliters of walnut oil, 100 to 150 milligrams of algal oil, 200 to 250 milligrams of grape seed extract, 50 to 80 milligrams of selenium-enriched yeast, 80 to 120 milligrams of vitamin C, 80 to 120 milligrams of vitamin E, 0.6 to 1.0 milligram of vitamin B1 (thiamine) and 0.6 to 1.0 milligram of vitamin B2 (riboflavin). After being taken by multiple persons for a period of time, the traditional Chinese medicine composition is proved to be safe to take, free of adverse reaction and obvious in health care effect, old people feel weak in action, heavy in whole body, dry in mouth and throat and insomnia and constipation before taking the traditional Chinese medicine composition, symptoms are relieved after taking the traditional Chinese medicine composition, and the traditional Chinese medicine composition is safe to take, free of adverse reaction and obvious in health care effect. Young people are good in working state and honor in spirit, and children are fast in learning progress, good in taste, high in adaptability and beneficial to popularization, and can play a positive role in prevention before illness.

The invention discloses an application of bead exosome-like nano-vesicles in treatment of Sjogren's syndrome. The bead exosome-like nano-vesicle is prepared through a differential centrifugation method and an ultracentrifugation method, and toxicological evaluation shows that the bead exosome-like nano-vesicle has good safety and can be used for in-vivo and in-vitro treatment. In-vivo experiments prove that the Sjogren's syndrome model mouse treated by the bead exosome-like nano-vesicles has significantly increased salivary secretion and significantly improved dry mouth symptom; in-vitro experiments further show that the nano vesicles can also significantly improve the activity and the water secretion function of salivary gland epithelial cells in the Sjogren's syndrome. The exosome-like nano-vesicles are successfully extracted from bead leaves and are creatively used for treating the Sjogren's syndrome, and a brand new thought and a material source are provided for research and development of medicines for treating the Sjogren's syndrome.

The invention belongs to the technical field of heating tobacco products, and provides an aerosol generating substrate and a preparation method thereof, an aerosol generating product, the aerosol generating substrate comprises a tobacco material, an aerosol forming agent and a taste improving agent, the taste improving agent comprises a calcium phosphate compound or a composition of the calcium phosphate compound and an oxide, and the taste improving agent comprises a calcium phosphate compound or a composition of the calcium phosphate compound and the oxide. The molar ratio of the calcium element to the phosphorus element in the taste improver is 1.1-2.0. The mouth feel improver is basically stable in processing or using environments such as high temperature and the like, does not release unpleasant substances and other substances without obvious sense organ positive promotion, has the capability of mildly improving acidic mouth feel, and does not generate mouth dryness.

The invention discloses artificial saliva and a preparation method of artificial saliva hydrogel. The artificial saliva is prepared from the following raw materials in parts by mass: 0.5 to 1 g of KCl, 0.2 to 0.4 g of K2HPO4, 0.2 to 0.8 g of NaCl, 0.2 to 0.4 g of KH2P O4, 10.04 to 20.8 g of CaCl2, 1.5 to 3 g of Nacaboxymethlecellulose, 60 to 120 mg of brown moss alcohol, 495 to 1000 ml of natural coconut juice and 5 to 10 ml of herba sarcandrae extract. By selecting the glabrous sarcandra herb extract, anti-inflammatory and anti-tumor treatment is realized, so that the traditional Chinese medicine composition has a remarkable effect on dry mouth caused by radiotherapy; through the form of a gel bead preparation, the beverage is more portable and unique in taste. The gel beads serve as one of oral local administration preparations, and after the gel beads are exploded, drugs can target small glands which are located below oral mucosa and secrete saliva, and the rapid drug effect is achieved. Direct local administration to the oral mucosa may provide rapid drug action, activate small salivary glands within the buccal mucosa, while avoiding systemic drug exposure and off-target effect.

Kit and method for treating patients with dry mouth syndrome. The kit includes a dental mouthpiece with one or more near-infrared light sources. Once placed in the oral cavity, it directs the light toward the selected target tissue (salivary glands, submandibular glands, or both) for the treatment of patients with dry mouth syndrome. The kit and method can be used to treat Sjögren's syndrome, patients taking multiple medications, diabetic patients, or patients with a reduced number of salivary glands, resulting in a marked, temporary, or permanent decrease in saliva production.

The present invention belongs to the technical field of traditional Chinese medicine, and mainly relates to a traditional Chinese medicine composition for clearing the throat and relieving sore throat, a traditional Chinese medicine preparation, and their preparation methods and applications. The traditional Chinese medicine composition is composed of the following traditional Chinese medicines in parts by weight: 0.9-1.5 parts by weight of Scrophulariae Radix, 1.2-5.0 parts by weight of Polygonati Odorati Rhizoma, 1.0-3.0 parts by weight of Glehniae Radix, 1.0-1.5 parts by weight of Rehmanniae Radix, 1.0-3.0 parts by weight of Ophiopogonis Radix, 1.5-6.0 parts by weight of Gypsum Fibrosum, and 0.5-3.0 parts by weight of Glycyrrhizae Radix. The preparation method of the traditional Chinese medicine preparation includes processes of processing, proportioning, extraction, concentration, soft material preparation, granulation, drying, and sizing. The traditional Chinese medicine composition or preparation for clearing the throat and relieving sore throat can relieve symptoms such as red and swollen pharynx, dry mouth and throat, sore throat, itchy throat, burning sensation, less phlegm, and foreign body sensation in the pharynx caused by pathogenic heat, and shows significant curative effect on the treatment of chronic pharyngitis. Through a unified preparation method, the quality and dosage accuracy of the medicinal materials used are ensured, as well as the stability of the treatment effect.

The application discloses a traditional Chinese medicine compound for treating Sjogren's syndrome and a preparation method and application thereof. The traditional Chinese medicine compound is prepared from Huangqi, Danshen, Maidong and Dendrobium officinale. The traditional Chinese medicine for treating Sjogren's syndrome has the functions of tonifying qi, generating fluid, nourishing yin, moistening dryness, promoting blood circulation and removing blood stasis. The traditional Chinese medicine for treating Sjogren's syndrome has unique advantages, can obviously improve the dry mouth, anti-fatigue, submandibular gland lymphocyte infiltration and T cell subpopulation proportion disorder of Sjogren's syndrome, and is an effective pure traditional Chinese medicine preparation.

The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for relieving muscles and penetrating rashes, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5-30 parts of pachouli, 10-40 parts of kudzu vine, 5-30 parts of notopterygium, 10-40 parts of talc, 5-30 parts of red peony root, 5-30 parts of thin soja bean, 5-30 parts of lophatherum gracile, 5-30 parts of raw rehmannia, and 10-30 parts of forsythia. The traditional Chinese medicine composition has the effects of dispelling dampness and relieving muscles, clearing heat and penetrating rashes, and can effectively improve the symptoms of fever, arthralgia, rash, fatigue, dry mouth and bitter taste, thick and greasy tongue fur and the like of patients with chikungunya fever caused by dampness stagnation in muscles and joints and heat entering the interior.

The present invention belongs to the technical field of edible and medicinal compositions, and specifically relates to an edible and medicinal composition for assisting in regulating blood sugar, and its preparation method, application, and preparation. The edible and medicinal composition is composed of mulberry leaves, black sesame seeds, polygonatum, and yam. Animal experiments of the present invention show that only four edible and medicinal substances, namely mulberry leaves, black sesame seeds, polygonatum, and yam, as the edible and medicinal composition can have a good hypoglycemic effect. Compared with the prior art, the composition of the present invention has simple components, reasonable compatibility, low cost, small dosage, and fast short-term hypoglycemic effect. The edible and medicinal composition of the present invention not only has a significant effect on lowering blood sugar after meals, but also has a significant effect on improving complications such as dry mouth and thirst that are common in "Qi and Yin deficiency type" diabetes. Its raw materials are natural and harmless, highly safe, and the overall nature and taste are sweet and flat, making it suitable for long-term use.

The utility model discloses a water feeder for relieving mouth dryness of a stomach tube patient. Comprising a water supply bottle and a clamping device, and the clamping device is used for clamping the water supply bottle; the water supply bottle comprises a water storage bottle and a telescopic suction nozzle, and the telescopic suction nozzle is installed on the water storage bottle; wherein the telescopic suction nozzle comprises a suction nozzle, a telescopic suction pipe and a shaping pipe, one end of the telescopic suction pipe is connected with the suction nozzle, and the shaping pipe is arranged on the periphery of the telescopic suction pipe in a sleeving mode and connected with the suction nozzle; and when the telescopic suction tube is elongated or shortened, the shaping tube and the telescopic suction tube are elongated or shortened, and the suction nozzle is elongated or shortened along the axis of the telescopic suction tube. The water supply bottle is clamped by one end of the clamping device, and the other end of the clamping device is fixed on the nursing bed, so that the water supply bottle can be conveniently adjusted to be close to the head of a patient; the length of the telescopic suction nozzle is adjusted, and the telescopic suction pipe and the shaping pipe are stretched or compressed, so that the suction nozzle extends to the mouth of the patient, the patient can suck drinking water only by slightly rotating the head, and the working efficiency of medical staff is improved.

This invention belongs to the field of traditional Chinese medicine, specifically relating to a traditional Chinese medicine composition for clearing heat and relieving irritability, its preparation method, and its application. The traditional Chinese medicine composition of this invention, by weight, comprises the following raw materials: 5-30 parts Asparagus root, 2-15 parts Chrysanthemum, 5-10 parts Imperata root, 2-5 parts Rose, 3-10 parts Lophatherum leaf, and 3-6 parts Tangerine peel. This traditional Chinese medicine composition for clearing heat and relieving irritability has the effects of clearing and moistening heart fire, relieving depression and irritability, calming the mind and aiding sleep. Clinical studies have shown that this traditional Chinese medicine composition for clearing heat and relieving irritability can effectively improve symptoms such as insomnia, excessive dreaming, palpitations, irritability, dry mouth, bitter taste, oral ulcers, and hypochondriac distension caused by liver qi stagnation and its transformation into fire disturbing the heart.

The invention discloses a traditional Chinese medicine heart nourishing and nerve soothing formula for treating insomnia. The formula is composed of spina date seed, mulberry, dendrobium, trichosanthes peel, cassia seed, dark plum, poria with hostwood and green plum blossom. The heart-nourishing and mind-tranquilizing formula is mainly used for nourishing the heart, tranquilizing the mind, nourishing yin, clearing heat, soothing the liver and relieving depression, and spina date seeds and poria with hostwood in the formula are used as monarch materials to nourish heart yin, tranquilize the mind, stabilize the mind and Mulberry, dendrobium and dark plum are used as ministerial drugs to nourish yin, promote salivation, clear deficiency heat and improve dysphoria, night sweat and dry mouth caused by fire excess from yin deficiency. The semen cassiae has the effects of clearing liver fire and relaxing bowel, and the semen cassiae and the semen cassiae can assist in clearing away the heart-fire and reducing phlegm; the green plum blossom can soothe liver depression without hurting yin, and is capable of soothing liver, harmonizing stomach and regulating qi. The prescription is used for overall conditioning of complex pathogenesis (yin deficiency, liver depression and phlegm heat) of insomnia, and is especially suitable for people with insomnia caused by high pressure, unsmooth emotion and staying up late at present. Compatible medication has local characteristics of new-safety medicine, is particularly beneficial to improvement of insomnia symptoms and the like, and is definite in curative effect and free of toxic and side effects.

A mouthpiece device and method for helping human users with congested sinuses breathe freely through their mouths while sleeping while minimizing the risks of dry mouth and drooling. The device fits between the user's jaws and is configured to apply a gentle jaw and lip opening pressure sufficient to at least partially open a sleeping user's jaw and lips while the jaw and lip muscles are relaxed. At the same time, the device is configured to so that when the user, while still sleeping, activates their jaw or lip muscles to swallow, this action overcomes the gentle opening force, allowing the user to easily swallow without conscious effort. Methods of configuring the device shape and opening forces are also taught. These include using implanted sensors, processors, and actuators configured to optimize the opening forces according to user physiology; and / or wireless connection to external sensing and control devices.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for dispelling wind and moistening dryness as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5 to 20 parts of folium mori, 5 to 15 parts of semen armeniacae amarae, 5 to 25 parts of bulbus fritillariae thunbergii, 5 to 25 parts of radix glehniae, 5 to 25 parts of radix ophiopogonis, 10 to 30 parts of rhizoma phragmitis, 10 to 20 parts of radix peucedani, 5 to 20 parts of herba menthae and 3 to 15 parts of liquorice root. The traditional Chinese medicine composition disclosed by the invention has the effects of dispelling wind, moistening dryness and clearing lung, can effectively relieve cough, throat itching and dry throat, dry lip and nose, no phlegm or less and sticky phlegm and difficulty in cough, or accompanied with dry mouth, pharyngalgia, body fever, headache, red and dry tongue with less saliva, thin white or thin yellow coating and floating pulse of a patient suffering from the flu wind-dryness syndrome, and can be used for treating the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu and wind-dryness syndrome of the flu. The traditional Chinese medicine has a good treatment effect on influenza wind-dryness syndrome.

This invention belongs to the field of traditional Chinese medicine preparation technology, specifically relating to a traditional Chinese medicine composition for treating dry mouth in Sjögren's syndrome and its preparation method. The traditional Chinese medicine composition includes the following raw materials in parts by weight: 10g Rehmannia glutinosa, 9g Scrophularia ningpoensis, 10g Ophiopogon japonicus, 10g Fagopyrum dibotrys, 10g Phragmites communis, 6g Amomum villosum, and 3g Bletilla striata. Depending on clinical diagnosis, other herbs such as Cornus officinalis, Trichosanthes kirilowii, Lophatherum gracile, Paeonia suffruticosa, and Poria cocos may be selectively added. The preparation method includes two decoctions, filtration, and combining the filtrates. It is derived from the Kidney-Nourishing, Heat-Clearing, and Yin-Nourishing Decoction, retaining the core of the Fluid-Increasing Decoction, and adding three lung / stomach meridian-invigorating herbs: Fagopyrum dibotrys, Phragmites communis, and Bletilla striata. The core treatment principle is to nourish yin and generate fluids, clear heat and remove blood stasis, promote tissue regeneration and wound healing, and harmonize the spleen and stomach. Clinical observation shows that it can significantly reduce the VAS score for dry mouth in patients with Sjögren's syndrome, increase static salivary flow rate, and promote the recovery of oral mucosal ulcers and angular cheilitis. It has good safety and can be taken orally for overall conditioning or used as a mouthwash to directly target the affected area.

The invention relates to spray for treating radioactive dry mouth of nasopharynx cancer patients after radiotherapy as well as a preparation method and application of the spray, and belongs to the technical field of biological medicines. The fusion protein comprises a lamin recombinant protein, an FGF8 recombinant protein and an Eda recombinant protein which are mutually fused and connected, the fusion protein is high in purity and relatively small in molecular weight after being purified in multiple steps, the fusion protein has the function of promoting salivary gland somatic cell regeneration in vitro, and the effect of the fusion protein is better than that of the fusion protein obtained from the lamin recombinant protein, the FGF8 full-length protein and the Eda full-length protein. The spray for treating radioactive xerostomia after radiotherapy of nasopharynx cancer patients is prepared from the fusion protein LFE, has the functions of promoting salivary gland cell regeneration and salivary secretion in vivo, has a treatment effect on radioactive xerostomia, and can be widely applied clinically.

The invention provides an external antipyretic pharmaceutical composition as well as a preparation method and application thereof. The composition consists of radix bupleuri, mint, gypsum, raw ephedra, elsholtzia, scutellaria baicalensis, isatis root and rhizoma smilacis glabrae. The preparation method comprises the following steps: mixing the eight medicinal materials, adding water, decocting, and sub-packaging the decoction into bags. Clinical tests prove that the buyi foot bath antipyretic prescription prepared by the invention can effectively improve clinical symptoms such as cough, lung signs, yellow and greasy tongue coating, slippery pulse, dry mouth and throat and the like of a child patient, can effectively reduce the number of disease days of the child patient and shorten the time for reducing the body temperature of the child patient to normal, does not have adverse events, and has a good clinical application prospect. The traditional Chinese medicine composition has obvious curative effects on reducing fever and body temperature of the pneumonia dyspnea and cough phlegm-heat closed lung syndrome and relieving clinical symptoms, and can be used for treating the infantile pneumonia dyspnea and cough phlegm-heat closed lung syndrome.

The invention belongs to the technical field of health-care food, and particularly relates to a medicated diet composition for improving eyesight, regulating spleen and increasing memory as well as a preparation method and application thereof. The medicated diet composition comprises the following raw materials in parts by mass: 9-45 parts of dried snow pears, 6-30 parts of lily bulbs, 3-15 parts of radix codonopsis, 2-10 parts of dried orange peel, 1-5 parts of dried ginger and 3-15 parts of mulberries. The medicated diet composition starts from regulating five internal organs, and gathers force in the liver and the spleen through delicate compatibility and the effect of promoting generation of the five internal organs, so that the effects of improving eyesight, regulating the spleen and increasing memory can be achieved, the efficacy can be lasting, meanwhile, cold and heat purgation and tonification are balanced through medicinal compatibility, and the defect that traditional tonics are poor in nature is overcome. Clinical tests show that the medicated diet composition can effectively improve the clinical symptoms such as eye dryness, eye itching, frequent blinking, memory deterioration, dry mouth or dry throat, poor appetite and the like of patients with liver and kidney deficiency and spleen and stomach deficiency in the sub-health state, and the life quality of the patients is improved.

The breathing assisting device comprises a machine body and a filtering assembly, a circuit board, a connecting cable and other electronic elements are arranged in the machine body, the filtering assembly is arranged on one side of the machine body and comprises a mixing groove and a filtering frame, the mixing groove is formed in one side of the machine body, and the filtering frame is arranged in the mixing groove. The filtering frame is a rectangular frame body with the two sides communicated, and a first rectangular filtering plate is fixedly connected to an opening in one side of the filtering frame. Air entering the machine body from the outside can be filtered under the action of the filtering assembly, small-particle impurities can be adsorbed and filtered under the action of components such as adsorption sponge, and the filtering efficiency is improved; small-particle impurities are prevented from entering the human body to affect health, high-pressure gas entering the human body is moistened under the action of the humidifying assembly, then the moistened gas can moisten the respiratory tract, and the situation that the oral cavity is dry due to long-time intake of the high-pressure gas is avoided.

The invention discloses a special-effect carsickness medicine formula and a preparation process. The special-effect carsickness medicine formula is prepared from the following natural herbal raw materials in parts by weight: 1.5-2.5 parts of plantain herb, 1.5-2.5 parts of viola inconspicua and 1.5-2.5 parts of kalimeris indica. The mechanism innovation is that the plantain herb, the viola inconspicua and the kalimeris indica are synergistically acted on nervous, gastrointestinal and balanced systems of dizziness, and the comprehensive remission rate is increased to 90%. Fast-acting property and durability coexist, the instant granules are taken under the tongue and take effect within 5 minutes, and the sustained-release patch is combined with the ginger extract and continuously acts for 8 hours, so that the requirement of long journeys is met. Natural components are high in safety and free of side effects, and common chemical side effects such as drowsiness and dry mouth in clinical tests are avoided.

The application provides a traditional Chinese medicine composition for treating or improving Sjogren's syndrome, and belongs to the technical field of traditional Chinese medicine pharmacy.The traditional Chinese medicine composition takes asparagus, lily and mulberry as monarch drugs, takes honeysuckle, semen astragali, rush and radix codonopsis as minister drugs, takes turmeric and atractylodes as auxiliary drugs, and takes licorice as a guide drug, and the drugs are combined to have the effects of nourishing yin and moistening dryness, clearing heat and dredging collaterals, tonifying qi and invigorating the spleen, and promoting blood circulation and improving eyesight.The traditional Chinese medicine composition can significantly reduce the water consumption of NOD mice, increase the saliva amount of NOD mice, significantly down-regulate the levels of inflammatory factors TNF-alpha, IL-17 and IL-1beta in the serum of NOD mice, improve the gland structure and lymphocyte infiltration in the submandibular gland tissue of NOD mice, and reduce the submandibular gland injury.In addition, the traditional Chinese medicine composition can significantly reduce the ESSDAI and ESSPRI scores of Sjogren's syndrome patients, improve the clinical symptoms such as dry mouth, dry eyes and salivary gland swelling of the patients, has a high total effective rate in clinical treatment, and can be further developed and researched as a drug for treating Sjogren's syndrome.

The application discloses a composition for preventing and treating osteoporosis and a preparation method and application thereof, and belongs to the field of biopharmacy. The method comprises the following steps: uniformly spraying a sodium bicarbonate aqueous solution on eucommia ulmoides oliver powder, sealing and infiltrating, and then slowly frying, spraying vinegar in the frying process, turning off the fire after the silk is broken, and then spreading and airing to reduce the temperature, and then extracting by ethanol reflux to obtain eucommia ulmoides oliver extract; sterilizing the drynaria rhizome powder at high temperature, adding lactobacillus plantarum after cooling, sealing and fermenting, and then extracting by ethanol reflux to obtain drynaria rhizome extract; and uniformly mixing the extracted eucommia ulmoides oliver extract and the drynaria rhizome extract, D-glucosamine hydrochloride, sodium chondroitin sulfate, epimedium extract and oyster powder to obtain the composition for preventing and treating osteoporosis. The eucommia ulmoides oliver is prepared by the method of sodium bicarbonate salt stir-frying and vinegar stir-frying, and the drynaria rhizome is treated by fermentation, so that the warm and dry properties of the original composition can be neutralized, the side effects of heatiness such as constipation, dry mouth, gum swelling and pain or sore throat can be reduced, and the safety and tolerance of the composition are improved.

The present invention belongs to the technical field of artificial saliva, and specifically discloses an artificial saliva, which is an aqueous solution containing cetylpyridinium chloride, HPMC, glycerol, electrolytes, sweeteners, preservatives, and pH regulators; wherein cetylpyridinium chloride is 0.01-0.12wt.%; HPMC is 0.2-2.5wt.%; and the content of glycerol is 1-5wt.%. In addition, the present invention also includes popping beads containing the artificial saliva and the preparation and application thereof. The artificial saliva of the present invention, based on the combination of the components, can synergistically improve the antibacterial and oral adhesion effects, and is innovatively prepared into a popping bead preparation, which can further improve its oral local application effect.