184 results about "Vitamin b6" patented technology

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

The invention discloses a stable vitamin B6 composition and a preparation method thereof. The pH value of the vitamin B6 injection is controlled to be 2.5-2.8, and the impurity content in the product is remarkably reduced by controlling the heating and cooling rate in the terminal sterilization process, so that the product stability and the clinical use safety are improved.

Various benefits to intestinal health are made by delivery of an active agent to the colon of an animal, including a human. Active ingredients include of riboflavin, vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, folic acid, β-carotene, vitamin B1, niacin, vitamin B5, vitamin B6, biotin, vitamin B12, omega-3 fatty acids and combinations thereof. Benefits include increased concentration of at least one short-chain fatty acid its salt thereof in the intestine, increased microbiome diversity in the intestine, increased beneficial bacteria in the intestine, increased the butyrate synthesis pathway in the intestine, improved barrier function of the intestine, reduced redox potential of the gut, reduced amount of gas produced in the intestine; and stimulation of intestinal immune responses.

The invention discloses a composition with a sleep improving function as well as a preparation method and application thereof, and the composition is prepared from the following raw materials in parts by weight: 50-100 parts of acanthopanax root, 30-50 parts of lotus seed, 50-100 parts of spina date seed, 30 parts of lily, 30 parts of longan, 30-50 parts of poria cocos, 30 parts of radix ophiopogonis, 10-30 parts of rehmannia, 10-30 parts of gastrodia elata, 2 parts of glutamic acid, 0.1 part of vitamin B, 0.1 part of vitamin B6 and 0.1 part of gamma-aminobutyric acid. The traditional single target spot limitation is broken through, a synergistic effect system of tonifying the spleen and soothing the nerves-neurotransmitter regulation and control-intestinal brain axis regulation is formed, a buffer solution of pH simulation biological fluid is adopted as a non-organic extraction medium in the process, the ultrasonic cavitation effect and the plasma activation effect are combined, the temperature is controlled in the whole process, and the preparation method is simple and easy to implement. The problems of vortex, uneven extraction, dead volume, solvent residue, active ingredient damage and the like in traditional extraction are fundamentally solved, the composition capable of effectively improving the sleep quality is obtained, and animal model and crowd experiments prove that the composition can effectively improve the sleep quality and achieve a good sleep aiding effect.

To provide a composition for hair capable of improving the volume of hair while suppressing the entanglement of hair, and to provide a hair treatment method using the composition for hair.SOLUTION: This composition for the hair is obtained by formulating (A) an amino acid-based cationic surface active agent with (B) one or more kinds selected from pantothenic acids, vitamin C or its salts, vitamin B3 or its salts and vitamin B6 or its salts. The hair treatment method uses the composition for hair.SELECTED DRAWING: None

The present invention provides a homocysteine-reducing composition that rapidly lowers blood homocysteine ​​levels to an appropriate level without causing any concerns about side effects. [Solution] A composition for reducing homocysteine ​​levels, comprising one or more B vitamins selected from vitamin B6, vitamin B12, and folic acid, and β-NMN as active ingredients. The β-NMN content is in the range of 22.32% to 89.29% by weight. Vitamin C and vitamin B2 may also be added.

The application belongs to the technical field of health products, and provides a growth-promoting amino butyric acid tablet and a preparation method thereof. 12 The preparation method of the amino butyric acid tablet is as follows: first, vitamin B1, vitamin B2, vitamin B6, vitamin B , vitamin D, folic acid and a first part of fillers are fully mixed and dried to obtain premix I; then, amino acids (gamma-amino butyric acid and L-lysine), the first part of premix I and a first part of binders are uniformly mixed; then, the remaining premix I is added and uniformly mixed to obtain premix II; then, calcium citrate, magnesium oxide, ferrous fumarate and sodium selenite are fully mixed, the remaining binders are dissolved in water and sprayed, wet granulation is carried out, and the granules are dried; finally, total mixing is carried out, and the tablet is pressed to be prepared. Through the improvement of the preparation process, the stability and content uniformity of B vitamins are improved, and the growth-promoting effect is improved.

This invention provides a method for culturing Aspergillus oryzae, a culture kit, a method for producing mycoprotein, and mycoprotein, all of which result in a culture of Aspergillus oryzae that is rich in γ-aminobutyric acid compared to ordinary Aspergillus oryzae, yields a large amount of microbial cells, and improves the mushroom-like flavor of the purified mycoprotein. [Solution] A method for culturing γ-aminobutyric acid-enriched Aspergillus oryzae is provided, characterized by adding glutamic acid and / or its salt and a vitamin B6-containing component to a culture medium for culturing the Aspergillus oryzae. A culture kit for γ-aminobutyric acid-enriched Aspergillus oryzae is also provided, comprising Aspergillus oryzae and a culture medium for culturing the Aspergillus oryzae, wherein the culture medium contains glutamic acid and / or its salt and a vitamin B6-containing component. Furthermore, a γ-aminobutyric acid-enriched mycoprotein and a method for producing the same are also provided, characterized by having a γ-aminobutyric acid content of 400 mg or more per 100 g dry weight of mycoprotein.

The present composition comprises magnesium-L-threonate and a neurotransmitter such as, but not limited to phosphatidylserine and optionally, at least one of vitamin C, vitamin B6, and vitamin D3. The composition has been shown to increase at least one of memory or cognition in clinical study subjects. The present disclosure is further directed to methods of identifying and a subject with a memory or cognitive deficiency and administering a therapeutically effective amount of a formula comprising magnesium-L-threonate and a neurotransmitter to improve the memory and / or cognitive deficiency. In some implementations, the magnesium-L-threonate is Magtein®. It is also intended that any other neurotransmitter that results in a synergistic composition of the magnesium-L-threonate and the neurotransmitter by administered to improve a subject's memory and / or cognition.

This invention discloses a culture medium for the mass sporulation of *Substantia macrantha* and its application. The culture medium comprises the following components: lactose 21-23 g / L, yeast extract 14-16 g / L, potassium chloride 0.4-0.6 g / L, magnesium sulfate 0.4-0.6 g / L, potassium dihydrogen phosphate 0.4-0.6 g / L, disodium hydrogen phosphate 0.55-0.75 g / L, sodium molybdate dihydrate 5-7 mg / L, vitamin B6 50-60 mg / L, arginine 20-30 mg / L, and agar 18-22 g / L, diluted to volume with double-distilled water, with a natural pH. Using the culture medium prepared according to this invention to culture *Substantia macrantha* significantly increases the spore yield (164-fold), reaching 2.21 × 10⁻⁶. 8 conidia / cm 2 This provides a reference for the mass production of the fungal spores.

The present invention provides a package of a micronutrient supplement for promoting the digestive function of the intestinal tract of a body, the micronutrient supplement consisting of two types of unit dosage forms in one package for sale to a purchaser wherein the first type of unit dosage form contains VB6 and a compound thereof, and the second type of unit dosage form contains VB6 and a compound thereof. The first type of unit dosage form contains Zn and compounds thereof, the second type of unit dosage form contains Zn and compounds thereof or VD and compounds thereof, and the first type of unit dosage form does not contain Zn and VD, and the second type of unit dosage form does not contain VB6, the micronutrient supplement being provided in a manner of administration twice a day, the first type of unit dosage form is taken in an awakening period, and the second type of unit dosage form is taken in a sleep period. The packaging product can be matched with the biological clock rhythm of an organism, the absorption and utilization rate of micronutrients is increased, and then the intestinal digestion function is improved.

This invention discloses a composition that helps improve sleep and its application in infant formula. The composition comprises plant fermentation products, theanine, magnesium oxide, milk mineral salts, ferric pyrophosphate, vitamin B6, vitamin C, and vitamin D3. The plant fermentation products are obtained by fermenting licorice powder, jujube seed powder, poria cocos powder, angelica powder, and hawthorn powder with *Lactobacillus helveticus* and *Lactobacillus rhamnosus*, followed by sterilization, filtration, concentration, and freeze-drying. This invention employs multi-strain mixed fermentation, and the synergistic effect between different microorganisms can effectively increase the concentration of natural active substances in the extract. The resulting plant fermentation products can effectively enhance the sleep-improving effect of the composition.

A skin-improving agent containing the following components (A)-(C). (A) at least one substance selected from the group consisting of L-cysteine, derivatives thereof, and salts thereof; (B) at least one substance selected from ascorbic acid, derivatives thereof, and salts thereof; and (C) one or more than two selected from the group consisting of vitamin B5, vitamin B6, vitamin B2, vitamin E, gamma-oryzanol, angelica sinensis and an extract thereof.

The invention belongs to the technical field of vitamin content detection, and particularly relates to a method for measuring the content of various water-soluble vitamins B. The water-soluble vitamins B comprise vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B7, vitamin B12 and nicotinamide. A high performance liquid chromatograph and an electrospray detector are used as detection instruments, and chromatographic conditions are as follows: a mobile phase A is ammonium formate or ammonium acetate, a mobile phase B is methanol, and gradient elution is performed; the gradient elution procedure is as follows: a solvent of a test sample is a mixed solution of acetonitrile, water and glacial acetic acid, and the volume ratio of the acetonitrile to the water to the glacial acetic acid is 5: 95: 0.5; the atomization temperature of the electrospray detector is 35 DEG C; the method is better in separation degree and higher in specificity and sensitivity.

The application discloses an Epithalon vitamin B6 coupled derivative and a preparation method and application thereof, and belongs to the technical field of medicines and cosmetics. The structure of the Epithalon vitamin B6 coupled derivative is: the Epithalon vitamin B6 coupled derivative has improved skin barrier passing ability and stability compared with vitamin B6 and Epithalon, has good stability, good transdermal effect, excellent health promotion and disease prevention functions such as sleep aid, and solves the defects of instability, poor permeability and inconvenient use of Epithalon and vitamin B6 in the prior art, and meanwhile, the Epithalon vitamin B6 coupled derivative has the functions of Epithalon and vitamin B6, and solves the technical problems of the need for separate addition of Epithalon and vitamin B6 in functional cosmetics and health products, the inactivation of Epithalon and vitamin B6 due to environmental influence, and short action time.

The invention discloses a preparation for improving male erectile function and sperm quality. The health-care food is characterized by being prepared from the following raw materials in parts by weight: 30-50 parts of herba epimedii extract, 20-40 parts of herba cistanche extract, 15-30 parts of fructus lycii extract, 18-35 parts of semen cuscutae extract, 10-25 parts of herba cynomorii extract, 8-20 parts of maca powder, 6-18 parts of raspberry extract, 0.5-2 parts of lycopene, 1-3 parts of L-carnitine and 0.3-1 part of vitamin B family (vitamin B1, vitamin B2, vitamin B6 and vitamin B12 are mixed according to the mass ratio of 1: 1: 2: 0.5). The herba epimedii extract is selected as a main component, the content of icariin is regulated to be not lower than 60%, the high-content icariin can more effectively promote sex hormone secretion, enhance sexual desire and improve erectile function, the total content of echinacoside and verbascoside in the herba cistanche extract is not lower than 45%, and the herba epimedii extract and the herba cistanche extract have the effect of promoting sex hormone secretion, enhancing sexual desire and improving erectile function. The two components have the effects of tonifying kidney yang and benefiting essence and blood, and can enhance kidney functions.

The invention provides saccharomyces cerevisiae INM3205 with high yield of vitamin B6 and application of the saccharomyces cerevisiae INM3205, the strain is saccharomyces cerevisiae INM3205, the strain is preserved in the Guangdong Microbial Culture Collection Center on July 16, 2025, the preservation number is GDMCC No: 66697, and the preservation address is the fifth floor, No. 59 building, No. 100 Courtyard, Xianlie Middle Road, Guangzhou City, Guangdong Province. The method has the advantages that the method has the capability of generating a flavor substance 2, 4-decadienal, so that the baked product is richer in flavor during the storage period.

The present disclosure relates to an oral product, a process for producing the oral product, as well as to uses of said oral product. The oral product is solid and in chewable form comprising a combination of active ingredients, wherein the combination comprises: (i) caffeine; (ii) a combination of B vitamins comprising at least vitamin B2, vitamin B3, vitamin B6, vitamin B9 and vitamin B12; and (iii) L-theanine; at least one binding agent; and at least one bulking agent selected from the group consisting of a sugar alcohol, or a sugar, or a combination of at least one sugar alcohol and at least one sugar.

The invention relates to the technical field of skin care, and discloses a composition for improving skin aging and a preparation method and application thereof. The feed additive is prepared from the following raw materials in parts by mass: 18 to 30 parts of yeast extract, 18 to 30 parts of rhizoma curcumae longae extract, 12 to 25 parts of mixed herbal extract, 12 to 25 parts of linear aspartame extract, 5 to 15 parts of green tea extract, 0 to 4 parts of vitamin B3, 0 to 3 parts of vitamin B5, 0 to 2 parts of vitamin B7, 0 to 2 parts of vitamin B12, 0 to 1 part of vitamin B6, 0 to 1 part of vitamin B1, 0 to 1 part of vitamin B2 and 0 to 1 part of folic acid. The preparation method of the capsule preparation comprises the following steps: taking the raw materials according to the mass parts of the composition, and uniformly mixing to obtain an intermediate product; controlling the mass content of water in the intermediate product to be less than or equal to 5.0% And filling the intermediate product into a plant-based capsule shell. Human body trial feeding verifies that the composition can effectively improve skin cell metabolism, relieve inflammatory response, clear ROS and AGEs, inhibit melanogenesis, promote skin hydration and delay skin photoaging.

This invention discloses a lutein-infused massage and care eye ointment containing precious Chinese medicinal herbs, free of eight major allergens, and suitable for all ages. Each tube contains 10 grams. The formula uses lutein as its core ingredient, combined with artificial musk, bear bile powder, pearl powder, ginseng, and Ganoderma lucidum, along with eye-protecting ingredients such as wolfberry, chrysanthemum, cassia seed, and buddleja flower. It is supplemented with sodium hyaluronate and vitamin B6, using medical-grade hypoallergenic petrolatum as a base. The ointment is strictly free of eight major allergens, making it safe and gentle, suitable for people aged 3 to 100. This invention features a simple process, can be industrially produced, and can effectively relieve eye fatigue, dry eyes, itchy eyes, bloodshot eyes, dark circles, eye bags, wrinkles, photophobia, and tearing in the wind, among other sub-healthy eye problems. It has extremely high market application and health care value.

The invention belongs to the technical field of aquaculture, and particularly relates to a decapterus maruadsi breeding feed and application thereof in improving the quality of decapterus maruadsi fertilized eggs. The invention provides a decapterus maruadsi breeding feed. The feed comprises a first feed and a second feed which are mutually independent, the first feed comprises a basal feed, fish cream and a nutrition enhancer; the second feed comprises the first feed and oyster meat; the nutrition enhancer contains calcium pantothenate, vitamin B1, vitamin B2, vitamin B6, vitamin C and vitamin F. When the culture feed for the decapterus maruadsi is used for performing nutrient enrichment on parent fishes of the decapterus maruadsi, synchronous development of sexual glands of male and female parent fishes of the decapterus maruadsi can be promoted, the quality of fertilized eggs of the decapterus maruadsi is improved, the good egg rate of the fertilized eggs of the decapterus maruadsi reaches 88.50% and is 39.15% higher than that of a control group, and the fertilization rate of the fertilized eggs reaches 79.58% and is 19.46% higher than that of the control group.

The present application relates to the technical field of nutritional supplement food, more specifically, to a double-protein balanced type of old-age nutritional supplement food and a preparation method thereof. The food comprises calcium, magnesium, zinc, iron, vitamin C, vitamin B6, vitamin E, vitamin B2, sodium selenite, nicotinamide, vitamin D3, vitamin A, vitamin B12, folic acid, vitamin B1 and vitamin K2. The present application is targeted at physiological characteristics and metabolic rules of middle-aged and old people, and scientifically proportioned various vitamins, minerals, essential fatty acids and antioxidant substances required by human body, so as to fully meet daily nutritional requirements of the middle-aged and old people and make up for insufficient dietary intake caused by decreased digestive and absorptive functions.

The invention provides a food composition for enhancing exercise tolerance as well as a preparation method and application of the food composition, and relates to the technical field of foods. The invention discloses a food composition. The composition is prepared from the following components in parts by weight: 6 to 16 parts of bovine blood oligopeptide, 10 to 20 parts of collagen, 1 to 3 parts of beta-carotene, 15 to 26 parts of radix codonopsis extract, 13 to 25 parts of pleurotus nebrodensis polysaccharide, 10 to 30 parts of isomaltooligosacharide, 5 to 10 parts of creatine, 4 to 10 parts of taurine, 0.2 to 0.6 part of vitamin B1, 0.2 to 0.6 part of vitamin B6, 5 to 15 parts of guarana extract, 4 to 12 parts of green tea extract and 4 to 12 parts of green coffee extract. 2-5 parts of L-carnitine, 5-12 parts of cordyceps militaris, 5-12 parts of red ginseng and 5-12 parts of lucid ganoderma. The obtained food composition has the effects of resisting fatigue and improving hypoxia tolerance, and is applied to preparation of food with the effects of enhancing exercise tolerance, resisting hypoxia and relieving fatigue.

The invention discloses a formula and a processing method for ecological culture of crustacean aquatic products, and the formula comprises the following medicines by weight: glycine / methionine chelated trace elements: by taking glycine as an example, not less than 13% of magnesium citrate, 9-20 g of magnesium citrate, not less than 21% of zinc glycinate, 5-9.5 g of zinc glycinate, not less than 15% of manganese glycinate, 3.5-6.5 g of manganese glycinate, not less than 15% of copper glycinate, and 1-2.5 g of copper glycinate; 6-11g of ferrous glycinate with the concentration of more than or equal to 17%; the selenium content of the yeast is 2,000 PPM, and is 1-1.5 g; per kilogram of the vitamin compound comprises 550000-8000000 IU of vitamin A, 150000-45000000 IU of vitamin D3, more than or equal to 3500 milligrams of vitamin E, more than or equal to 1200 milligrams of vitamin K3, more than or equal to 800 milligrams of vitamin B1, more than or equal to 5000 milligrams of vitamin B2, more than or equal to 800 milligrams of vitamin B6, more than or equal to 2000 micrograms of vitamin B12 and more than or equal to 15000 milligrams of vitamin C; the invention relates to the technical field of aquaculture, the formula realizes the virtuous cycle of efficient absorption, sedimentation, slow release, decomposition and supply of trace elements through artificial and natural synergistic nutrition chain design, and achieves the ecological breeding target of'zero emission 'of nutrient substances and'zero addition' of chemical agents.

The present invention relates to a nutritional vitamin complex for pets intended to improve the fur and skin quality of pets such as dogs and cats. The composition of the complex contains omega-3, curcumin, piperine, biotin (vitamin H or vitamin B7), vitamin B2 (riboflavin), vitamin B3 (nicotinic acid or niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 (cyanocobalamin), folic acid (vitamin B9), vitamin E (alpha-tocopherol), vitamin C, zinc (zinc glycine chelate), coenzyme Q10, hydrolysed type II collagen, astaxanthin, DL-methionine, selenium, L-glycine, L-proline, L-phenylalanine, L-leucine, L-isoleucine, L-histidine, L-arginine, L-lysine, L-tyrosine, resveratrol, and a flavouring agent.

The invention discloses eye health care liquid based on cortex berberidis and saffron crocus extracts and a preparation method of the eye health care liquid, and relates to the technical field of traditional Chinese medicine preparations and eye health care, in particular to the eye health care liquid based on the cortex berberidis and saffron crocus extracts and the preparation method of the eye health care liquid. According to the eye health-care liquid, a cortex berberidis extract and a saffron crocus extract are used as main active ingredients, a fructus lycii extract, a radix stemonae extract, a mint extract, a honeysuckle flower extract and other functional ingredients are used as auxiliary ingredients, and sodium hyaluronate, taurine and vitamin B6 are added to enhance the moisturizing, anti-oxidation and metabolic regulation effects. The preparation method comprises the steps of raw material extraction, extract concentration, auxiliary material mixing and pH adjustment, filtration and sterilization and the like. The product is suitable for eye atomization application, has the effects of relieving eye inflammation, improving microcirculation, relieving dryness, redness and swelling and the like, meanwhile strictly controls heavy metal and microbiological indexes, and guarantees use safety.

The invention belongs to the field of wastewater treatment, and discloses a method for treating vitamin B6 wastewater, which comprises the following steps: 1, diluting filtered vitamin B6 wastewater to CODlt; the concentration is 60000 mg / L, and obtaining first wastewater. And 2, carrying out subcritical water catalytic oxidation on the first wastewater to obtain second wastewater. And 3, adding alkali into the second wastewater for deamination to obtain third wastewater. 4, freezing the third wastewater to extract sodium phosphate dibasic dodecahydrate crystals, so as to obtain fourth wastewater. And 5, circularly carrying out membrane concentration treatment on the fourth wastewater, returning membrane concentrated water to the step 2, carrying out subcritical water catalytic oxidation, carrying out evaporative crystallization on membrane permeate liquid to obtain sodium chloride, and freezing the membrane concentrated water after each time of membrane concentration treatment to extract disodium hydrogen phosphate dodecahydrate crystals. And 6, refining the disodium hydrogen phosphate dodecahydrate wet product to obtain the industrial trisodium phosphate dodecahydrate. According to the method, the high COD removal rate is achieved, and phosphate and sodium chloride are recycled.

The application discloses a composition containing burdock polysaccharide for reducing blood sugar of type 2 diabetes patients and a preparation method and application thereof, and belongs to the technical field of medicine and food. The composition contains burdock polysaccharide, chitooligosaccharide, chlorogenic acid, epicatechin, resveratrol, ginsenoside Rd, and vitamin D, vitamin B1, vitamin B6, vitamin B12, magnesium glycinate and thaumatin protein. The application takes burdock polysaccharide as a core long-acting component, takes chitooligosaccharide as a short-acting synergistic component, constructs a long-short-acting synergistic blood sugar reducing system, and realizes the organic combination of rapid blood sugar reduction and stable blood sugar control. Experiments show that the composition can significantly reduce the fasting blood sugar of type 2 diabetes model rats, improve insulin resistance and glucose tolerance, reduce blood lipid and inflammatory factor levels, and reduce oxidative stress damage. The alpha-glucosidase inhibitory activity and in-vivo comprehensive blood sugar reducing effect of the composition are better than those of single burdock polysaccharide, and the composition has good taste and is suitable for long-term use of diabetes patients.

The present invention relates to a nutritional vitamin complex for pets intended to improve the fur and skin quality of pets such as dogs and cats. The composition of the complex contains omega-3, curcumin, piperine, biotin (vitamin H or vitamin B7), vitamin B2 (riboflavin), vitamin B3 (nicotinic acid or niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B12 (cyanocobalamin), folic acid (vitamin B9), vitamin E (alpha-tocopherol), vitamin C, zinc (zinc glycine chelate), coenzyme Q10, hydrolysed type II collagen, astaxanthin, DL-methionine, selenium, L-glycine, L-proline, L-phenylalanine, L-leucine, L-isoleucine, L-histidine, L-arginine, L-lysine, L-tyrosine, resveratrol, and a flavouring agent.

The invention provides a sustained-release medicinal preparation for preventing and treating alopecia as well as a preparation method and application of the sustained-release medicinal preparation, and belongs to the technical field of biological medicines. The medicine for preventing and treating alopecia is prepared from the following components: 1 to 2.5 mg of finasteride, 4 to 6 mg of minoxidil, 20 to 60 mg of spirolactone, 10 to 20 mg of isotretinoin, 3 to 8 mg of vitamin B5, 50 to 100 mg of zinc and 5 to 10 mg of vitamin b6. The components cooperate with one another to activate hair follicle stem cells, increase the number of hair follicles and synergistically enhance the ability of promoting hair regeneration, so that a better alopecia prevention and treatment effect is achieved; the pharmaceutical preparation prepared by selecting a specific filler, an adhesive, a sustained-release framework material and a lubricant in a reasonable proportioning range has good sustained-release performance, the dosage and frequency of the medicine are greatly reduced, and the side effect is far lower than that of an oral medicine in a common dosage form.