The invention discloses a Ictalurus punctatus compound feed, the contents of mass ratio of characteristic materials are as follows: vitamin A 0.005-0.007, vitamin D3 0.004-0.006, vitamin E 0.070-0.090, vitamin K3 0.002-0.004, vitamin B1 0.003-0.005, vitamin B2 0.005-0.007, vitamin B6 0.08-0.012, vitamin B12 0.001-0.003, nicotinamide 0.030-0.050, calcium pantothenate 0.10-0.30, folic acid 0.01-0.03, biotin 0.001-0.002, VC-phosphate 0.300-0.400, inositol 0.070-0.090, antioxidants 0.200-0.300, wheat-middlings 1.000-1.200, ferrous sulfate 0.400-0.600, copper sulfate 0.010-0.030, zinc sulfate 0.150-0.200, manganese sulfate 0.100-0.150, iodine 0.050-0.150, Se 0.050-0.070, cobalt chloride 0.010-0.030, magnesium sulfate 1.000-1.500, zeolite powder 5.0-6.0, xylo-oligosaccharide 0.008-0.012, bacillus licheniformis 0.01, weatings 90.-110., wheat-middlings 110-130, rice bran 75-85, soy bean powder 55-65, soybean meal 190-210, peanut meal 25-35, fish meal 95-105, cottonseed meal 75-85, rapeseed meal 110-130, gem meal 45-55, soybean oil 15-25, lysine 0.8-1.2, methionine 0.8-1.2, salt 2.0-2.5, betaine 3-5, allicin 0.1-0.3, choline chloride 1.0-2.0, calcium dihydrogen phosphate 15-25. Compared with other feeds, the usage rate of feed nutrient ingredients for Ictalurus punctatus is increased by 10-15%, feed coefficient is reduced by 5-10%, feed waste is reduced, nitrogen and phosphorus excretion of Ictalurus punctatus in the environment is reduced, at the same time the survival rate of Ictalurus punctatus is improved significantly.