275 results about "Laboratory mouse" patented technology

The utility model relates to a laboratory mouse rearing cage which comprises a cage body, a side door, a partition plate, a hook, an electronic weighing device and a sliding rod. The side door is arranged on one side wall of the cage body, the electronic weighing device is arranged on one side of the bottom of the cage body, the sliding rods are arranged on the top of the cage body at equal intervals, the height of the partition plate is smaller than that of the cage body, the hooks are arranged on the top of the partition plate at intervals, and the hooks can be hung on the sliding rods. The cage body is divided into the weighing area and the feeding area through the partition plate, when a mouse needs to be weighed when the mouse is fed to a preset time period, the hook is lifted to lift the partition plate, the mouse is driven to the electronic weighing device, the partition plate is put down to prevent the mouse from escaping, the whole mouse can be easily and simply weighed, and therefore the test efficiency is improved, and manpower is saved.

The invention discloses an experimental mouse motion behavior identification method based on depth dynamic perception, and the method comprises the following steps: firstly, constructing an experimental mouse attitude estimation algorithm based on feature focusing and depth fusion, introducing a key point feature focusing mechanism based on SMamba in the algorithm, inhibiting background interference, and obtaining a motion behavior of an experimental mouse; and designing a depth feature fusion module based on cross cyclic convolution, and enhancing the positioning robustness of the key region in the shielding scene. Then, on the basis of the posture estimation algorithm, mouse key point heat maps are extracted to form spatio-temporal feature input of behavior recognition, an experimental mouse behavior recognition algorithm based on double-branch attention perception is constructed, and a skeleton spatio-temporal feature dynamic perception technology based on double-branch attention is introduced into a behavior recognition backbone network; differentiated expression and dynamic modeling of the target behavior are realized, so that four typical motion behaviors of face washing, head raising, turning around and standing of the experimental mouse are accurately identified.

The invention provides a virtual reality multi-sensory stimulation virtual reality system for a stroke laboratory mouse, which relates to the technical field of medical experiments and comprises a treadmill, a treadmill adjusting component, a weight reduction system, a visual system, an auditory stimulation system, a tactile stimulation system, an olfactory stimulation system, a reward and punishment system, an information acquisition system and a main control system. According to the invention, by designing the weight reduction system, the movement of the experimental mouse is adjusted, the virtual reality multi-sensory stimulation experiment of the stroke experimental mouse which cannot support 100% of the weight of the mouse can be realized, and a visual system, an auditory stimulation system, a tactile stimulation system, an olfactory stimulation system and a reward and punishment system are matched; post-stroke nerve remodeling and motion mode reconstruction are promoted through multi-sensory-channel stimulation, and an important foundation is laid for the next step that virtual reality is used for human body rehabilitation training.

The invention discloses an application of a polypeptide Apelin-13 in a medicine for treating psoriasis, in particular to psoriasis-like skin lesion. In an imiquimod (IMQ) cream induced mouse psoriasis model, intraperitoneal injection of Apelin-13 can significantly reduce scale, erythema and skin thickness, and can inhibit proliferation of epithelial spine cells. HE staining and immunohistochemical staining are carried out on the skin tissue of an experimental mouse, and the result shows that Apelin-13 can reduce the expression of the psoriasis marker protein K17, the thickness of the surface layer of the back side skin of the experimental mouse and the downward extension of a spinous layer. Experimental mouse serum ELISA (enzyme-linked immunosorbent assay) detection results show that the Apelin-13 can be used for down-regulating IL-17A (interleukin-17A) which is highly expressed in psoriasis. The polypeptide Apelin-13 can be used as a medicine for treating psoriasis, especially a medicine for treating psoriasis-like skin lesion.

The invention discloses a laboratory mouse fixing mechanism and an explosion experiment device, and relates to the technical field of experiment auxiliary equipment. The conical barrel is of a hollow structure and is provided with a first end and a second end, the diameter of the first end is smaller than that of the second end, and the second end is detachably connected with one end of the barrel body; the fixing structure is arranged on the barrel and comprises a fixing plate and a guide assembly, the fixing plate is clamped in the barrel, the guide assembly comprises a sliding block and a sliding groove, the sliding groove is formed in the side wall of the barrel in a penetrating mode, the length direction of the sliding groove is consistent with the axial direction of the barrel, and the sliding block is clamped in the sliding groove and is in sliding connection with the sliding groove. One end of the sliding block is fixed to the fixing plate. The experimental mouse fixing device has the advantages that the body of an experimental mouse can be fixed through the fixing structure, the head of the experimental mouse can be fixed through the conical barrel, and the better fixing effect is achieved. Meanwhile, a structure for adjusting the angle of the fixing mechanism is arranged, so that the injury degree of explosion to the head of the laboratory mouse at different angles can be studied.

The invention relates to a construction method and application of a loneliness mouse model, and the method comprises the steps: placing an experimental mouse in an isolation region in a transparent acrylic isolation cover through an environment in which physical isolation and social deprivation stimulation coexist, forming a visually accessible but physically isolated social environment with five normal living mice, and continuously inducing chronic loneliness for 4 weeks. The effectiveness of the model is verified through a multi-dimensional evaluation system, including behavioristics (open field, elevated maze and three-box experiment), neuroendocrine (serum noradrenaline and angiotensin II), immune inflammatory factors (IL-1beta, IL-6, TNF-alpha and CCL5) and nerve activation (blue spot, almond nucleus, lateral nucleus septum, medial prefrontal cortex and center joint dorsal nucleus C-Fos staining) indexes. According to the intervention method, dynamic environment abundance and social stimulation are adopted, running wheels are arranged, a modular abundance device is arranged, and a social environment of new mice is introduced, so that pathological phenotypes caused by loneliness are reversed. And a systematic experiment tool is provided for exploring association of aloneness and diseases.

The invention provides a construction method of an invasive candida infection model. The construction method comprises the following steps: S1, laboratory mouse selection, S2, drug preparation, S3, pretreatment, S4, bacterial load observation, S5, candida culture treatment, S6, intragastric administration, and S7, monitoring state evaluation. According to the method, the real state of invasive infection caused by translocation and dissemination of candida colonization from the digestive tract of a clinical candida infected patient can be simulated, the method is closer to clinical practice, the variety and abundance of native flora in the digestive tract of an experimental mouse are reduced through early-stage antibiotic pretreatment, then candida colonization in the digestive tract is achieved through intragastric administration, and the clinical practice is facilitated. Under the action of an inducer, colonized candida is induced to invade and spread through the digestive tract, the invasive candida infection mouse model can be successfully constructed, and the model can highly restore risk factors and pathogenic processes of clinical invasive candida infection and has a good application prospect.

The invention discloses a construction method and application of a bacterium-derived depression mouse model, and belongs to the technical field of biological medicines. The method comprises the following steps: randomly grouping SPF (specific pathogen free) grade C57BL / 6J experimental mice; using drinking water quadruple antibiotics or intragastric administration quadruple antibiotics to deplete mouse background intestinal flora; according to the method, a freshly prepared Eggera tarda bacterial liquid is applied to male mice of 7-9 weeks old in an intragastric administration manner, and the bacterial-derived depression mouse model is constructed. According to the construction method disclosed by the invention, by directly planting the Eggera tarda which has a definite causal relationship with the major depression, multivariable interference introduced by a traditional complex mental stress model is avoided, and a'bacterial origin 'animal model which is more single in variable, clearer in causal relationship and clearer in mechanism is constructed; and an efficient and reliable experimental tool is provided for accurately explaining the specific action mechanism of the'microorganism-intestine-brain axis' mediated by the Eggera tarda in the occurrence and development of the depression.

The utility model provides an efficient out-of-focus myopia model based on an anti-scratch lens fixing device, which comprises a gauze ring, a base, a mounting cylinder and a lens, the inner wall of the lower end of the base is glued with the gauze ring used for shading and dust prevention, and the upper side of the base is movably clamped with the mounting cylinder used for mounting the lens. Compared with the prior art, the laboratory mouse has the advantages that the base is arranged, the through holes in the side edge of the base are matched with the gauze, so that the eyes of the laboratory mouse can be ventilated, the situation that the experiment result is affected by eye discomfort caused by sealing is avoided, and dust and bacteria in the external environment can be intercepted; by matching with sponge columns of which the interiors of spaced through holes are fully sucked with silver ion antibacterial agents, the antibacterial effect can be effectively achieved, infection caused by the influence of bacteria on eye products of laboratory mice is avoided, the stable fixing performance is provided through deformation by arranging a protection plate and a mounting cylinder on the base, and then the lens is fixed more stably.

The invention belongs to the technical field of construction methods of disease animal models, and particularly relates to a construction method and application of a renal syndrome hemorrhagic fever mouse model. According to the HTNV infected mouse model established by the method disclosed by the invention, the symptom of the experimental mouse is close to the clinical symptom of a severe hemorrhagic fever with renal syndrome after challenge, the complete lethality and repeatability are high, and the HTNV infected mouse model has the advantages of simple operation, low cost and high efficiency. The method can be used for research on the HTNV pathogenic mechanism and immune mechanism and research and development of antiviral drugs and vaccines, and has great application value for perfecting an HTNV full-chain prevention and control system.

The utility model relates to a water feeding structure for experimental animal feeding, which comprises a water inlet pipe, a water outlet pipe and a water outlet pipe, the drainage assembly is installed at the bottom of the water inlet pipe, and the drainage assembly is used for guiding water of the water inlet pipe into the cage. According to the water feeding structure for experimental animal feeding, the drainage assembly is arranged, water of the water inlet pipe can be guided into the drainage groove of the drainage block, opening and closing of the drainage groove are achieved through the locking mechanism, the hidden drinking design can avoid the problem that a water source is exposed in the air for a long time and is polluted and deteriorated, and the service life of the water feeding structure is prolonged. The problem that bacteria breed in the cage due to damp when the water basin is overturned can be avoided, and the water drinking requirements of a plurality of laboratory mice can be met at the same time.

A laboratory mouse subcutaneous injection fixing device comprises a workbench, a fixed housing, a positioning support rod, a movable plate, a positioning lock sleeve, a threaded support rod and a fastening retaining ring, an injection opening is formed in the upper portion of the fixed housing, a bearing plate is arranged on the lower portion of the fixed housing, a plurality of supporting legs are connected to the lower portion of the bearing plate, the supporting legs are connected with balancing weights, and a limiting baffle is arranged on the upper portion of the bearing plate. The limiting baffle is connected with the workbench, the lower portion of the workbench is connected with the bearing plate, the bearing plate is provided with sliding blocks, the two sides of the workbench are provided with sliding ways, the sliding blocks are matched with the sliding ways, the sliding blocks are connected with the sliding ways, the sliding blocks slide on the sliding ways, the sliding ways are provided with sliding grooves, the sliding grooves are matched with the rollers, the rollers are connected with the sliding grooves, and the rollers slide on the sliding grooves and are connected with the sliding blocks through shaft rods. The shaft rod is sequentially connected with the sliding block and the roller.

The invention relates to the technical field of laboratory devices, in particular to an intelligent intraperitoneal injection auxiliary fixing device for laboratory mice, which comprises a basic bearing module, and a mouse fixing module, a pressure monitoring module, a control module, an indication module and a power supply module which are mounted on the basic bearing module, wherein the mouse fixing module is used for fixing a mouse, the mouse fixing module comprises a lower arc-shaped latticed clamping plate, an upper arc-shaped clamping plate, a connecting piece and a hook lock, the lower arc-shaped latticed clamping plate and the upper arc-shaped clamping plate are connected through the connecting piece, and the upper arc-shaped clamping plate and the lower arc-shaped latticed clamping plate are jointly matched to clamp the mouse; the abdomen of the mouse faces the lower arc-shaped latticed clamping plate, the hook lock is used for fixing the upper arc-shaped clamping plate and the lower arc-shaped latticed clamping plate, the pressure monitoring module can monitor the stress condition of the mouse in real time, compressive stress or suffocation of the mouse is avoided, and animal welfare is improved.

The utility model discloses a laboratory mouse multi-layer three-dimensional cage structure which comprises a supporting bottom plate for feeding laboratory mice, two ends of the supporting bottom plate extend to form mounting plates, two sides of the supporting bottom plate are provided with side plates, the top of each mounting plate is provided with a separation net, each mounting plate is provided with a ventilation plate, and the other side of each mounting plate is provided with a mounting groove. An inserting groove is formed below the mounting groove, a turning cover plate is mounted in the inserting groove, and a supporting layer is inserted in the inserting groove; a water feeder is installed on the side plate, a feeding opening is further formed in the side plate, and a feeding trough is installed outside the side plate; the multi-layer three-dimensional layout is achieved through the slot type supporting layer, the space utilization rate is increased, the water feeder and the feeding system are independent, the requirement of experimental mice for the activity space is met, and separation net holes are matched with the transparent observation plate to form the three-dimensional activity space; due to the inclined plane design of the feeding trough and the sealing structure of the flip head, the feed residue rate is reduced; the inserting groove type supporting layer is matched with a supporting block locking structure, and the excrement leakage risk is completely eradicated.

The utility model relates to the technical field of experimental animal feeding device design, and discloses an easy-to-clean experimental mouse feeding cage which comprises a feeding box, a hollow inhabitation platform is arranged in the feeding box, and the inhabitation platform divides the feeding box into an inhabitation space and a dirt storage space in the vertical direction. The joints of the adjacent side walls in the inhabiting space and the joints of the inhabiting platform and the four walls in the inhabiting space are all in an arc-shaped connection mode, a box cover is arranged at the top of the feeding box, a guide groove is annularly formed in the top wall of the feeding box, a scraping plate is arranged on the inner side wall of the inhabiting space in an attached mode, the top end of the scraping plate is rotationally connected with a driving plate, and the driving plate is arranged in an L shape; the vertical part of the driving plate is inserted into the guide groove, a driving assembly is arranged in the guide groove, a collecting box is arranged at the inner bottom of the feeding box in a sliding mode, the collecting box is located below the hollowed-out through hole of the inhabiting platform, and a box door is hinged to the position, corresponding to the collecting box, of the feeding box. The cleaning device has the effect of improving the working efficiency of cleaning the laboratory mouse rearing cage.

The utility model discloses a perfusion fixing device for animal experiments. The perfusion fixing device comprises a base; two first threaded cylinders are arranged on the first threaded rod; each second threaded rod is provided with two second threaded cylinders; the supporting plate is arranged between the pair of second threaded rods; and the head fixing plate is arranged at the top of the base. According to the perfusion fixing device provided by the utility model, the positions of the four limb fixing pieces, the position of the head fixing piece and the height of the supporting plate can be adjusted according to the body sizes of laboratory mice, so that the laboratory mice with different body sizes can be stably clamped, and the application range of the perfusion fixing device is greatly expanded; the device can be widely popularized and applied in the field of animal experiment equipment.

The utility model provides a laboratory mouse sterile feeding isolator, which comprises a mounting bracket, a feeding device, an isolating device, an isolating device, an isolating device and a control device, wherein the mounting bracket is provided with a feeding space; the storage device is connected with the feeding space and comprises a storage cavity provided with a first storage opening and a second storage opening; the first opening and closing device is arranged at the first storage opening; the second opening and closing device is arranged at the second storage opening; the second opening and closing device comprises a second opening and closing door; the hook is arranged on the side, close to the second opening and closing door, of the storage cavity; the fixing piece is arranged on the side, away from the storage cavity, of the second opening and closing door, and a kidney-shaped hole is formed in the fixing piece; the connecting rod penetrates through the kidney-shaped hole, and when the second opening and closing door is closed, the connecting rod is arranged on the hook; and the rotating piece is arranged on the connecting rod in a sleeving mode, and the rotating piece and the connecting rod are eccentrically arranged. According to the embodiment of the utility model, the operation convenience of experimenters is improved.

The application provides a laboratory mouse tail skinner and an operating method thereof, which comprises a base, a cutting mechanism comprising a first assembly ring and a plurality of cutting assemblies, any cutting assembly comprising a first mounting seat and a cutting knife, the cutting knife being arranged on the first mounting seat and extending towards the center of the first assembly ring, and a skinning mechanism comprising a second assembly ring and a plurality of skinning assemblies, the second assembly ring being arranged concentrically with the first assembly ring, and the skinning assembly comprising a second mounting seat and a skinning knife, the skinning knife being connected to the second mounting seat and facing along the axial direction of the second assembly ring. The application replaces manual operation of a handheld blade with a mechanical structure, effectively avoiding the safety hazard of a sharp blade scratching the fingers of a laboratory worker. In addition, the application has a simple body structure and is convenient to assemble, can flexibly adjust the positions of the cutting assemblies and the skinning assemblies according to laboratory mouse tails of different specifications, has a wide range of applications, and has high practicality and promotional value.

The utility model aims to provide an auxiliary device for taking out an eyeball retina specimen of an experimental mouse, which relates to the technical field of medical instruments and is characterized in that during use, a cornea of a taken-down eyeball of the mouse is placed below an operating cylinder upwards, and an arc-shaped sheet is controlled to clamp the cornea by rotating a cover plate of a reducing mechanism; mouse eyeballs of different sizes can be fixed through the diameter changing mechanism, in the moving process, the arc-shaped piece abuts against the blade to move towards the circle center of the base to be attached to the cornea, the mounting ring is rotated to cut the cornea, then the clamping mechanism slides downwards to be close to and clamp the cornea and the crystalline lens, and the cornea and the crystalline lens are separated. Then, the optic cup-shaped tissue with the cornea and the crystalline lens removed is reversed, the clamping rod continues to be used for fixing the optic nerve, the cup opening of the optic cup-shaped tissue abuts against the arc-shaped piece, then the clamping rod translates downwards, and the internal retina tissue is completely extruded out of the optic cup-shaped tissue through the innate subretinal space; therefore, an eyeball retina specimen is obtained.

The utility model relates to the technical field of laboratory mouse feeding, and discloses a laboratory mouse heat preservation feeding box which comprises a feeding box body, a supporting plate is fixedly connected to the inner side wall of the feeding box body, a supporting column is fixedly connected to the top of the supporting plate, and a connecting frame is fixedly connected to the top of the supporting column. The breeding box comprises a breeding box body, a connecting frame is fixedly connected to the outer side of the breeding box body, two symmetrically-distributed rotating columns are rotationally connected to the interior of the connecting frame, rotating rods are fixedly connected to the outer sides of the rotating columns, the number of the rotating rods is four, every two adjacent rotating rods are rotationally connected with each other, and connecting rods are fixedly connected to the outer sides of the rotating columns close to the side wall of the breeding box body. The outer side of the connecting rod is rotationally connected with a connecting piece, and the top of the supporting plate is fixedly connected with an air cylinder. The heat preservation breeding box for the laboratory mice has the advantages that the breeding box does not need to be opened, the mice in the breeding box are fed regularly and quantitatively, and the temperature in the breeding box is kept stable.

This utility model discloses a transport box for laboratory mice with an anti-collision and buffer structure, including an outer anti-collision box and an inner placement box. The placement box holds the laboratory mice, and the outer wall of the placement box is provided with multiple buffer blocks, which are placed between the outer anti-collision box and the placement box. Both the outer anti-collision box and the top of the placement box are provided with door opening and closing components. The top and bottom of the placement box are provided with upper and lower buffer components, and the opposite side wall is provided with side buffer components. The upper and lower buffer components and the side buffer components are all set in conjunction with the buffer blocks. This utility model provides basic anti-collision protection through the outer anti-collision box, and with the buffer blocks on the outer wall of the placement box, it can initially mitigate the impact of external collisions. The upper and lower buffer components and the side buffer components work together to effectively absorb the vertical and lateral vibrations and bumps during transportation, reducing the stress response or physical injury to the laboratory mice caused by collisions and bumps.

The invention belongs to the technical field of animal model construction, and particularly provides a construction method and application of a mouse non-alcoholic fatty liver model, and the construction method comprises the following steps: S1, selecting an experimental mouse; s2, a high nitrogen compound aqueous solution with the mass concentration of 4-10 mg / mL is prepared; s3, according to the dosage, the dosage and the administration time, the prepared high-nitrogen compound aqueous solution is fed through the intragastric administration, and the non-alcoholic fatty liver animal model is obtained, the problems that an existing non-alcoholic fatty liver animal model is long in modeling time and expensive in modeling are solved, and the non-alcoholic fatty liver animal model does not need to be fed with high-fat feed, and is simple, convenient and feasible, low in cost, good in repeatability and stable; the establishment period of the non-alcoholic fatty liver animal model can be effectively shortened, the time cost of the medical research of the NAFLD is greatly saved, and a good animal model is provided for researching the pathogenesis and treatment strategy of the NAFLD.

The invention discloses a laboratory mouse feed and a preparation method thereof. The feed consists of the following raw materials in percentage by weight: 32-38% of corn flour, 22-28% of fermented soybean meal, 8-12% of fish meal, 4-6% of silkworm chrysalis meal, 10-15% of low-gluten wheat flour, 2-3% of purple perilla seed oil, 1.5-2.5% of calcium carbonate, 0.8-1.2% of calcium hydrophosphate, 0.3-0.5% of table salt, 0.8-1.2% of microencapsulated compound vitamins, 0.2-0.4% of an enzyme preparation compound, 3-5% of dietary fibers and the balance of mineral premix. The preparation method has the beneficial effects that the vitamin retention rate of the technical scheme is increased by 30-40% compared with a contrast, and the problem of nutrient loss caused by a traditional high-temperature process is solved; the water uniformity is improved by 68% through gradient cooling, the quality guarantee period is prolonged from 50 days to 85-95 days in combination with a microencapsulation technology, and the storage loss is reduced.

A rat and mouse fixing device is used for meeting the requirement for fixing an operation model animal with a device on the back, improving the comfort degree of fixing an experimental mouse, reducing animal stress, prolonging the service life of the model animal, improving the test operation efficiency and enabling test data to be more accurate. Which comprises a cylinder capable of containing a laboratory mouse, a conical thin shell is fixedly arranged at the front end of the cylinder, and vent holes are formed in the shell wall of the conical thin shell at intervals, and is characterized in that an annular groove which annularly extends from the top to the two sides by a certain arc length is formed in the front portion of the cylinder, and a longitudinal groove which longitudinally extends forwards from the rear end is formed in the top of the cylinder; the annular groove and the longitudinal groove are communicated to form a T-shaped groove; and a mouse blocking mechanism capable of moving along the longitudinal groove is arranged at the rear part of the cylinder.

The invention discloses a method for researching an influence mechanism of gastrodin on anxiety-like behaviors after sleep deprivation, and relates to the technical field of pharmacology and behavioral psychology. Comprising the following steps: selecting an ICR male mouse, establishing a sleep deprivation model through an improved multi-platform water environment method, and observing the influence of the expression level of autophagy related protein of the model group mouse on the anxiety-like behavior of the mouse; the method comprises the following specific steps: S1, experiment preparation and reagent preparation; s2, experimental animal grouping; s3, establishing a sleep deprivation model; s4, performing a sleep deprivation experiment and dosing; s5, performing open field experiment on the mouse; s6, performing an elevated cross maze experiment on the mouse; and S7, performing experimental statistics. According to the application, the influence of gastrodin on anxiety-like behaviors of mice after sleep deprivation is systematically discussed for the first time, the action mechanism of the gastrodin is disclosed from the perspective of autophagy related protein, and a new perspective is provided for clinical application of the gastrodin; the mouse sleep deprivation model is successfully established through an improved multi-platform water environment method, and the method is simple and easy to implement and high in repeatability.

The application discloses a method for constructing a Parkinson's disease animal model with improved survival rate and application thereof, and relates to the biomedical field, and comprises the following steps: S1, injecting a gepefron solution into the abdominal cavity of an experimental mouse; S2, performing brain stereotactic injection on the experimental mouse by using a 6-OHDA solution; S3, injecting meloxicam into the abdominal cavity of the experimental mouse, and dynamically adjusting the dosage of meloxicam based on the daily weight change of the experimental mouse; S4, performing postoperative nursing on the experimental mouse, including nutritional support and graded gavage; and S5, performing behavior testing, pathological verification and inflammation evaluation on the experimental mouse, and obtaining a Parkinson's disease animal model through the above steps. The application has the advantages of high postoperative survival rate of the animal and high success rate of modeling.

The utility model discloses an automatic feeding device for laboratory mice, which belongs to the technical field of automatic feeding and comprises a bottom plate, a quantitative feeding mechanism is arranged above the bottom plate, and an alarm mechanism is arranged above the bottom plate. The quantitative feeding mechanism is arranged, the alternating-current power supply box supplies power to the electric actuator, the direct-current power supply box and the slide rheostat are matched to provide 4-20 mA electric signals for the electric actuator, the resistance value of the slide rheostat can be adjusted according to different weights of laboratory mice, and therefore the direct current is adjusted, and the feeding efficiency is improved. The opening degree of a valve is adjusted through an electric actuator, the feeding amount of laboratory mice with different weights is adjusted, meanwhile, an alarm mechanism is further arranged, when food is little, the weight of the food cannot press a sliding plate downwards by an enough distance, an alarm rod cannot make contact with an alarm, and when the alarm rod does not make contact with the alarm, the alarm triggers an alarm, and the alarm rod cannot make contact with the alarm. And a worker is reminded of insufficient food in the storage tank, so that the worker can add the food in time.

This utility model relates to a simple experimental mouse fixation and tail vein injection device, including a fixation platform, a transparent isolation cover, and a tail fixation component. The transparent isolation cover is used to cover the experimental mouse on the fixation platform. An isolation cover notch is formed at the edge of the open end of the transparent isolation cover, through which the tail of the experimental mouse protrudes. The tail fixation component is used to fix the protruding tail of the experimental mouse on the fixation platform. This utility model combines experimental mouse fixation, tail fixation, and visual monitoring, achieving a dual improvement in drug administration accuracy and simplified experimental operation. It can be operated by a single person and is suitable for precise drug delivery and real-time image monitoring in small animal experiments, possessing high practical value and promising prospects for widespread application.

The invention relates to a laboratory mouse fixing device which comprises a fixing table, a glass plate is fixedly mounted at the top of the fixing table, a water outlet is formed in the top of the fixing table, and a fixing mechanism is arranged at the top of the fixing table. According to the fixing device for the laboratory mouse, the laboratory mouse is placed on the glass plate and is slightly pressed and fixed by an experimenter, the controller drives the electric push rod to drive the living body scanner to move downwards, so that the laboratory mouse is scanned, the controller drives the motor to start according to a scanning result after scanning is completed, and then the multiple sets of fixing clamps can be driven to move in the opposite directions; in the experiment process or after the experiment is completed, the controller can be operated to drive the booster pump to start the water in the water tank to be guided into the water collecting box through the water inlet pipe and sprayed out through the spray head, and the water in the water tank is sprayed out through the spray head. Excrement of the laboratory mouse on the glass plate is flushed.

The utility model relates to the field of laboratory mouse fixers. A universal rapid fixing clamp for laboratory mice comprises a supporting bottom plate and further comprises four-limb fixing mechanisms used for fixing four limbs, each four-limb fixing mechanism comprises an elbow clamp, and a first sliding groove used for being detachably connected with the corresponding four-limb fixing mechanism is formed in the supporting bottom plate; the neck fixing mechanism is used for fixing the neck, and a second sliding groove used for being detachably connected with the neck fixing mechanism is formed in the supporting bottom plate; the device further comprises a waist and back fixing mechanism used for fixing the waist and the back, a third sliding groove used for being detachably connected with the waist and back fixing mechanism is formed in the supporting bottom plate, the waist and back fixing mechanism comprises a supporting frame, a pressing block and a pressing plate, and the pressing plate is connected with the supporting frame through an elastic mechanism. According to the experimental mouse fixing device, multi-dimensional fixing of an experimental mouse is achieved through the four-limb fixing mechanism, the waist and back fixing mechanism and the neck fixing mechanism, and the fixing effect is greatly improved.