20 results about "Laboratory mouse" patented technology

The application provides a laboratory mouse tail skinner and an operating method thereof, which comprises a base, a cutting mechanism comprising a first assembly ring and a plurality of cutting assemblies, any cutting assembly comprising a first mounting seat and a cutting knife, the cutting knife being arranged on the first mounting seat and extending towards the center of the first assembly ring, and a skinning mechanism comprising a second assembly ring and a plurality of skinning assemblies, the second assembly ring being arranged concentrically with the first assembly ring, and the skinning assembly comprising a second mounting seat and a skinning knife, the skinning knife being connected to the second mounting seat and facing along the axial direction of the second assembly ring. The application replaces manual operation of a handheld blade with a mechanical structure, effectively avoiding the safety hazard of a sharp blade scratching the fingers of a laboratory worker. In addition, the application has a simple body structure and is convenient to assemble, can flexibly adjust the positions of the cutting assemblies and the skinning assemblies according to laboratory mouse tails of different specifications, has a wide range of applications, and has high practicality and promotional value.

This utility model discloses a transport box for laboratory mice with an anti-collision and buffer structure, including an outer anti-collision box and an inner placement box. The placement box holds the laboratory mice, and the outer wall of the placement box is provided with multiple buffer blocks, which are placed between the outer anti-collision box and the placement box. Both the outer anti-collision box and the top of the placement box are provided with door opening and closing components. The top and bottom of the placement box are provided with upper and lower buffer components, and the opposite side wall is provided with side buffer components. The upper and lower buffer components and the side buffer components are all set in conjunction with the buffer blocks. This utility model provides basic anti-collision protection through the outer anti-collision box, and with the buffer blocks on the outer wall of the placement box, it can initially mitigate the impact of external collisions. The upper and lower buffer components and the side buffer components work together to effectively absorb the vertical and lateral vibrations and bumps during transportation, reducing the stress response or physical injury to the laboratory mice caused by collisions and bumps.

This utility model relates to a simple experimental mouse fixation and tail vein injection device, including a fixation platform, a transparent isolation cover, and a tail fixation component. The transparent isolation cover is used to cover the experimental mouse on the fixation platform. An isolation cover notch is formed at the edge of the open end of the transparent isolation cover, through which the tail of the experimental mouse protrudes. The tail fixation component is used to fix the protruding tail of the experimental mouse on the fixation platform. This utility model combines experimental mouse fixation, tail fixation, and visual monitoring, achieving a dual improvement in drug administration accuracy and simplified experimental operation. It can be operated by a single person and is suitable for precise drug delivery and real-time image monitoring in small animal experiments, possessing high practical value and promising prospects for widespread application.

This invention discloses a blueberry anthocyanin nutritional solid composition for relieving eye discomfort. The composition comprises blueberry anthocyanin solid powder, algal oil powder, zinc gluconate, and selenium-enriched yeast, and may optionally contain lipid nutrients containing gamma-linolenic acid, as well as food additives and excipients. Oral administration of this composition provides the body with various nutritional supports related to ocular surface function and ocular moisture, helping to maintain tear secretion levels, improve tear film stability, and support the normal physiological state of the corneal epithelium, thereby relieving eye dryness and discomfort caused by environmental stimuli or increased eye strain. Animal experiments showed that after 14 days of continuous administration of the composition, experimental mice exhibited a significantly increased tear secretion volume compared to the control group without the composition, with an increase of approximately 165%. Corneal fluorescein staining scores were also significantly reduced, indicating improved ocular surface condition and significantly enhanced eye comfort.

1. Name of the product in this design: Mouse restraint device. 2. Purpose of this design: To fix experimental mice during blood glucose testing. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

This utility model discloses an auxiliary device for tail vein injection in medical experimental mice. Relating to the technical field of medical experimental equipment, the device includes a base with a fixing frame installed near the edge of the top. A fixing component is provided on the top of the base, and an observation component is provided on one outer wall of the fixing frame. The fixing component includes a lower fixing plate and an upper fixing plate, with the upper fixing plate positioned above the lower fixing plate. This auxiliary device for tail vein injection in medical experimental mice allows the upper fixing plate to move upward a certain distance by pulling a lever, overcoming the spring's thrust, and completely separating the upper and lower arc-shaped plates. The mouse is then placed on the lower arc-shaped plate. Releasing the lever causes the upper arc-shaped plate to move downward under the spring's thrust, thus securing the mouse and effectively avoiding the problem of mice being difficult to stabilize due to their active and restless nature.

A posterior nasal nerve dissection and retractor for laboratory mice, belonging to the field of medical device technology, solves the technical problem of limited anatomical space and inconvenient instrument operation during posterior nasal nerve resection in laboratory mice. The solution includes clamps, a limiting rack, and a supporting leaf spring. The inner side of the tail of one clamp handle is fixedly connected to one end of the limiting rack. A first locking hole is provided on the inner side of the tail of the other clamp handle, and the other end of the limiting rack is movably inserted into the first locking hole. The supporting leaf spring is cross-arranged within the area enclosed by the clamp handles and the limiting rack on both sides. Symmetrical light guide grooves are provided between the opposing surfaces of the two clamp heads, and symmetrical grooves are provided between the opposing surfaces of the outer ends of the two clamp heads. A dissector and a retractor are detachably installed in the grooves on both sides, respectively. A protective plate is detachably installed on the outer surface of the clamp head near the retractor. This invention provides a new tool for establishing a stable and reliable experimental mouse model of posterior nasal nerve resection.

This utility model relates to the field of laboratory animal technology in barrier environments, specifically to an automatic water replenishment device for laboratory mice, comprising a mounting plate, a water storage box, a water replenishment pipe, a control pipe, a control column, a mouse cage, a feeding box, and a feeding assembly; the mounting plate is vertically mounted on a wall, the water storage box is mounted on top of the mounting plate, the water replenishment pipe is disposed inside the water storage box with one end located outside the water storage box, and a water purifier is connected to the outer end of the water replenishment pipe, the control pipe is installed in the middle of the water replenishment pipe, the control column is installed inside the control pipe, the mouse cage is mounted on top of the mounting plate with the cages spaced apart, the feeding box is installed inside the mouse cage, and the feeding assembly is installed inside the mounting plate, with the feeding assembly located above the feeding box.

This invention relates to the field of biological experimental equipment technology, specifically to a herbal sitz bath device for laboratory mice. The device includes several mouse cages suspended above a water bath, a fixture mounted on the side wall of each cage, and a sitz bath window adjuster mounted at the bottom of each cage. The fixture is used to softly hold the mouse within the cage and allows it to slide upwards to exit. The sitz bath window adjuster is used to adjust the size of the opening at the bottom of the cage to accommodate mice of different sizes with their anal area exposed in the herbal solution. This invention utilizes a fixture composed of soft clips and a sliding plate. An arc-shaped airbag elastically holds the mouse's limbs and presses them onto the sliding plate. The height of the sliding plate is customized according to the distance between the mouse's forelimbs and hindlimbs. This achieves the goal of avoiding hard damage to the mouse during holding while allowing the mouse to slide upwards and its head to smoothly exit the cage when the fixture is lifted. This solves the technical problems of traditional fixation methods, which easily lead to stress, friction damage, and difficulty in removal from the mouse.

This utility model relates to a temporary storage cabinet for laboratory mice, comprising: a first cabinet having a first inner cavity and a first opening, the first opening and the first inner cavity being in communication; a second cabinet having a second inner cavity and a second opening, the second opening and the second inner cavity being in communication, and the first cabinet and the second cabinet being connected, thereby enabling the first inner cavity of the first cabinet and the second inner cavity of the second cabinet to communicate; the first opening and the second opening being in communication; a door frame assembly including a door frame body and a pivot post, the pivot post being disposed on the door frame body and capable of pivoting relative to the first cabinet and the second cabinet, thereby enabling the door frame body to open and close the first opening and the second opening; and a lock assembly mounted on the door frame body, the lock assembly being used to lock the door frame body onto the first cabinet and the second cabinet.

This invention belongs to the field of biomedical experimental equipment and provides a biological X-ray irradiation cage specifically for laboratory mice. It includes a cage bottom cover with an open cage box cover. A fixed central axis assembly is provided between the bottom cover and the cage box cover. The fixed central axis assembly includes a fixed shaft rotatably mounted on the cage box cover, and several partitions are arranged circumferentially on the fixed shaft. This invention uses a fixed cage to fix the relative positions of the animals in each irradiation location to the irradiation unit, ensuring that the irradiated animals receive equal irradiation distances within the conical radiation area generated by the irradiation unit. The cage height is set to match the body thickness range of the laboratory mice, and partitions are placed between each animal to ensure stable posture, preventing them from standing or stacking, and keeping them at the same horizontal level from the radiation source, achieving consistent irradiation doses and ensuring objective and accurate experimental results.

This invention discloses a method for dynamically and non-invasively evaluating the effects of oral health supplements on the liver based on Micro-CT technology, comprising the following steps: S1, experimental grouping and treatment: experimental mice are divided into a blank group, a model group, and at least one sample group; S2, after injecting all experimental mice with the nanoparticle contrast agent ExiTron nano 6000, liver scans are performed using Micro-CT. After the scans are completed, the raw data are reconstructed into three-dimensional images, and the area under the curve of the standard deviation of liver parenchyma CT values ​​from 0 to 28 days is calculated using CTAn software; S3, definition and evaluation of liver damage. This invention utilizes Micro-CT imaging technology to evaluate the effects of oral health supplements on the liver of mice by dynamically monitoring changes in liver morphology and density, and is particularly suitable for safety assessment and biological effect analysis of health supplements at the liver level.

This application provides a method, device, electronic device, and storage medium for monitoring laboratory mice, belonging to the field of laboratory mouse monitoring technology. The method includes: acquiring multiple consecutive video frame data and experimental physiological data of laboratory mice in a smart breeding cage collected within a preset acquisition time slot; inputting the visual feature information corresponding to the video frame data into a target detection model to perform target analysis operations, obtaining target location information and identification information of the laboratory mice; determining location verification result information based on the identification information and the target location information corresponding to the multiple video frame data; inputting the identification information, the visual feature information corresponding to each video frame data, and the target location information into a behavior detection model to perform behavior detection operations, obtaining target behavior information of the laboratory mice; if the location verification result information and target behavior information meet preset conditions, determining the experimental physiological data as the target physiological data of the laboratory mice. This application can improve the accuracy of physiological data acquisition.

The utility model discloses an experimental mouse feeding frame with smell isolation structure, including the feeding frame that a plurality of isolation frames constitute, and a plurality of isolation frames are fixed by a plurality of support poles, the front support pole is equipped with the hole of inserting, and a plurality of hole of inserting are installed with the isolation board, the support pole is installed with the splicing subassembly, and a plurality of isolation frames are matched and installed with experimental mouse feeding case, the isolation board is equipped with the hole of releasing gas, and the hole of releasing gas is installed with the sealing cover, the utility model discloses the sealing groove and the sealing strip cooperation of isolation frame front and back two sides, can closely adhere to experimental mouse feeding case outer wall, and the gap between feeding case and frame is blocked, and the accurate positioning installation of isolation board through the hole of inserting, positioning groove and fixed groove, and the convenient disassembly and installation, and the high maintenance cleaning efficiency, the splicing subassembly adopts T type splicing groove and splicing block design, and the length of both is identical, and one end penetrates one end sealing, guarantees the adhesion and stability when splicing of adjacent isolation frame, and also is convenient for quick assembly or disassembly.

The utility model discloses a kind of scraping brush devices of automatic cleaning experimental mouse cage, including experimental mouse cage body, transparent observation plate is installed in experimental mouse cage body two sides, top is equipped with cover plate, experimental mouse cage body is installed with scraping brush subassembly in another two sides;Mobile groove is opened in experimental mouse cage body two sides, mobile rod is installed in mobile groove;The scraping brush subassembly includes moving cylinder, the sleeve ring is connected in the moving cylinder output end, the inside of the sleeve ring is also connected with scraping pole;The utility model moves cylinder by sleeve ring and drives scraping pole to move up and down along mobile rod, scraping pole on two sides encloses cage inner wall to form full coverage cleaning area, without manual wiping;The brush bar of scraping pole side is through dense bristle to loosen stain, the arc scraping strip of other side can scrape stubborn dirt, ensure that cage inner wall has no residue;The brush bar is matched with the T type of scraping pole T type of insertion slot Matching connection, can be quickly disassembled and replaced worn bristle.

This utility model provides an animal modeling device, comprising: a support base; a limiting cylinder fixedly installed on the top of the support base; a transparent cylinder disposed on the inner side of the limiting cylinder; and a limiting ring fitted onto the top of the outer side of the transparent cylinder. The animal modeling device provided by this utility model, through the coordinated structure of the limiting ring, limiting frame, moving frame, connecting frame, and perforated plate, allows the operator to move the moving frame upwards when the experimental mouse reaches the preset modeling state in the ice-water mixture within the transparent cylinder. The moving frame causes the connecting frame and the perforated plate at the bottom to rise, and the perforated plate lifts the experimental mouse, allowing it to quickly separate from the ice-water mixture without the need for clamps or other tools to reach into the water and grasp it. This avoids the difficulty of grasping the mouse due to its swimming motion, improves separation efficiency, and ensures the accuracy of the modeling process.

The utility model relates to mouse enema experimental apparatus technical field, especially in kind of mouse enema device for experiment, the utility model discloses a silica gel hose, silica gel soft plug and charge mechanism, the front end of silica gel hose is provided with a plurality of liquid outlet holes, and charge mechanism includes medicine bucket and piston rod, and the end of piston rod is provided with press handle, in the utility model, through the insertion of silica gel hose in the anus of experimental mouse, the anus of experimental mouse is pressed against by moving silica gel soft plug on silica gel hose, then through piston rod, the enema liquid in medicine bucket is pushed into silica gel hose, and the anus of experimental mouse is entered from the liquid outlet hole of the front end of silica gel hose, in the utility model, adopt the insertion of silica gel hose in the anus of experimental mouse, and it is not easy to cause too big reaction of experimental mouse, makes it not easy to move disorderly, and through piston rod, the enema liquid in medicine bucket is pushed into silica gel hose and then enters the anus of experimental mouse, convenient operation and practical.