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Data storage method based on large model
ActiveCN119292524Aefficient storageefficient retrievalInput/output to record carriersBiological models
The invention relates to the technical field of data storage management, in particular to a data storage method based on a large model. The method comprises the following steps: performing input class cluster fragmentation optimization on a target pre-training large model to obtain storage modulus fragmentation data; constructing an intelligent fragmentation storage strategy by using the storage modulus fragmentation data; obtaining target model training data; performing intelligent fragmentation storage on the target model training data by using an intelligent fragmentation storage strategy, and performing redundancy compression optimization to obtain dynamic redundancy storage index data; and training data storage space optimization is carried out according to the dynamic redundancy storage index data, and an optimized data storage strategy is obtained. According to the method, intelligent fragmentation storage and refined data redundancy compression are performed on the data, so that efficient and stable model training data access is realized, the problem of low data storage and access efficiency in a large model training process is solved, and the model training efficiency and reasoning real-time performance are remarkably improved.
Owner:JIANGXI GONGBO NETWORK TECHNOLOGY CO LTD
Power dispatching model lightweight method and system under meta universe, and storage medium
PendingCN119273019Aefficient loadingData processing applicationsNeural learning methodsLevel of detailSimulation
The invention relates to a lightweight method and system for a power dispatching model under meta-universe and a storage medium, and the method comprises the following steps: carrying out the intelligent data simplification of a three-dimensional model based on a deep learning adaptive reduction compression technology in combination with an advanced texture mapping and curve thinning algorithm, so as to optimize the details of the model and reduce the data size, thereby achieving the intelligent data simplification of the three-dimensional model; meanwhile, key features are reserved; through power grid cascade loading and visual elimination, display details of a power grid model are dynamically adjusted according to the visual angle of an observer, and model resource management and dynamic scheduling are realized through asynchronous loading and rendering; in combination with an intelligent preloading and prediction mechanism, a multi-level-of-detail technology and a progressive loading technology are applied to realize rapid loading and rendering of the model, and resource allocation and detail management are refined. According to the invention, the lightweight processing of the three-dimensional model of the power dispatching element universe can be realized, and the goals of real-time efficient rendering and rapid interaction of meteorological data, power grid operation information and a plant station equipment model are achieved.
Owner:STATE GRID TIANJIN ELECTRIC POWER COMPANY +2
Mitochondria-loaded cell membrane vesicle preparation as well as design method, preparation method and application thereof
PendingCN119385968Afast loadingefficient loadingNervous disorderMetabolism disorderNatural sourceDisease
The invention discloses a design and preparation method of a cell membrane vesicle preparation loaded with mitochondria. The design method comprises the following steps: loading the mitochondria into an artificially constructed cell membrane bionic vesicle, and constructing a nano-scale vesicle preparation loaded with the mitochondria inside and a cell membrane outside; the preparation method comprises the following steps: preparing cells into a cell suspension; repeatedly extruding the cell suspension through an extrusion device provided with a filter membrane with a specific aperture; and carrying out differential centrifugation on the extruded liquid to prepare the cell membrane vesicle preparation loaded with mitochondria. The invention also discloses the vesicle preparation obtained by the method and application of the vesicle preparation in preparation of drugs for treating mitochondrial damage related diseases. According to the method, rapid and efficient loading of mitochondria in cells can be realized, and the problems of low yield of mitochondria vesicles from natural sources, limited loading efficiency and the like are solved. The prepared vesicle preparation can effectively protect the physiological function of mitochondria, delay rapid inactivation of mitochondria in the using process and achieve efficient mitochondrial transplantation of damaged cells.
Owner:ZHEJIANG UNIV
Electro-transfection buffer solution and application thereof in exosome loaded polypeptide
ActiveCN119139482Aincrease loading capacityefficient loadingPeptide/protein ingredientsInorganic non-active ingredientsDipotassium phosphateExosome
The invention discloses an electrotransfection buffer solution and application of the electrotransfection buffer solution in exosome loaded polypeptide, and relates to the technical field of biology. The electrotransfection buffer solution is prepared from the following components: 80 to 120 mM of trehalose, 6 to 10 mM of dipotassium phosphate, 12 to 16 percent of iodixanol and a buffer solution. The invention also provides a method for carrying out exosome drug loading by using the electrotransfection buffer solution, more efficient loading of palmitoyl pentapeptide-4 by the exosome is realized, the loading capacity of molecules is improved on the premise of not losing the exosome, a higher collagen expression level can be obtained, and the method disclosed by the invention can be applied to large-scale and large-scale production. And the subsequent yield requirement is met.
Owner:SHENZHEN WINGOR BIO TECH
Colorimetric-fluorescent bimodal nanoprobe for detecting cMyBP-C and micro-fluidic chip
ActiveCN119395300Aefficient loadingavoid interferenceMaterial analysis by observing effect on chemical indicatorBiological material analysisAntiendomysial antibodiesEngineering
The invention discloses a colorimetric-fluorescent bimodal nanoprobe for detecting cMyBP-C and a micro-fluidic chip, and belongs to the technical field of biomedical detection and in-vitro diagnosis. The colorimetric-fluorescent bimodal nanoprobe which takes UCNPs as a core and MOF as a shell and is loaded with horse radish peroxidase and a labeled antibody is prepared by providing a layer-by-layer self-assembly technology; the micro-fluidic chip is prepared according to the probe, the micro-fluidic chip can realize cMyBP-C colorimetric and fluorescence signal bimodal detection, and the technical problems of limited sensitivity, susceptibility to background interference, limited linear range, photobleaching phenomenon, signal instability and the like in single signal detection are solved.
Owner:SHANGHAI XINMIAO BIOLOGICAL TECHNOLOGY CO LTD
Convolutional neural network hardware acceleration system based on Zynq
PendingCN119647537Aefficient accessImprove loading speedArchitecture with single central processing unitEnergy efficient computingActivation functionData stream
The invention discloses a Zynq-based convolutional neural network hardware acceleration system, which is realized based on a Zynq heterogeneous chip and comprises a PL end module, a PS end module and a storage module. The PL end module comprises a convolution acceleration module, a full connection layer acceleration module and a Softmax activation module and is used for completing convolution calculation, full connection operation and activation function processing; the PS end module comprises an input data processing module and a post-processing module and is responsible for loading and preprocessing input data and sorting and screening detection results. The storage module is composed of an on-chip memory and an off-chip memory, wherein the on-chip memory stores an intermediate processing result of input data, a convolution kernel and intermediate feature map data; and the off-chip memory stores the original image data, the weight parameter of the full connection layer and the final detection result. All the modules are connected through a 64-bit AXI bus, the PS end module is responsible for coordinating data flow, and the PL end module executes efficient parallel computing. The system makes full use of the high-performance characteristic of the Zynq heterogeneous architecture, is suitable for an efficient reasoning acceleration scene of the convolutional neural network, and particularly has a wide application prospect in embedded AI equipment.
Owner:GUILIN UNIV OF ELECTRONIC TECH
Browser code block loading method and device, equipment, medium and program product
ActiveCN119576437Aefficient loadingflexible loadingMathematical modelsProgram loading/initiatingProgramming languageCoding block
The invention provides a browser code block loading method and device, equipment, a medium and a program product, and relates to the technical field of computers.The method comprises the steps that first identification information of a first module in a target system currently accessed by a target browser is obtained, and second identification information corresponding to a second module is determined based on the first identification information, the second module is a next module accessed by the target browser predicted based on the first module; according to the first corresponding relation, determining a first new characteristic list corresponding to the second identification information, and screening out a second new characteristic list which does not support the target browser from the first new characteristic list corresponding to the second identification information; the first corresponding relation is a corresponding relation between identification information of each module in the target system and a first new characteristic list corresponding to each module; and when the second identification information is consistent with the identification information of the next module actually accessed by the target browser, outputting the polyfill code block corresponding to the second new characteristic list to the target browser.
Owner:CHINA MOBILE (SUZHOU) SOFTWARE TECH CO LTD +1
Deodorization type chicken manure treatment device
ActiveCN224077220UImprove processing efficiencyachieve hybridSludge treatmentRotary stirring mixersBiotechnologyAgricultural science
The utility model discloses a deodorization type chicken manure treatment device which comprises a feeding box, through holes are formed in the two sides of the bottom of the feeding box, a conveying mechanism penetrates through the through holes and comprises a conveying pipeline, a servo motor is installed at the left end of the conveying pipeline, and an output shaft of the servo motor is connected with an auger through a coupler; a box body is mounted at the top end of the conveying pipeline, and a second through hole communicated with an inner cavity of the box body is formed in the conveying pipeline. The chicken manure deodorization device relates to the technical field of chicken manure deodorization, the conveying mechanism is arranged, chicken manure in the conveying pipeline is conveyed through an auger, and meanwhile, a spraying mechanism on the conveying pipeline sprays a deodorant onto the chicken manure; then the chicken manure sprayed with the deodorant is conveyed by the auger in the conveying pipeline, so that the deodorant and the chicken manure are mixed, the chicken manure is conveyed while being mixed, and the chicken manure treatment efficiency is improved; and the chicken manure can be conveniently guided, so that the treated chicken manure is unloaded into a transfer trolley or a carriage, and the loading of the chicken manure is more efficient.
Owner:LESHAN LONGXIANG MASCH MFG CO LTD
Coal mine conveying device for coal mine excavation
ActiveCN222273199Uefficient loadingEfficient unloadingCleaningSupporting framesMining engineeringElectric machine
The utility model relates to the technical field of conveying, and discloses a coal mine conveying device for coal mine excavation, which comprises a base, a rotating column is rotatably connected to the middle side of the upper part of the base, the upper end of the rotating column is rotatably connected to the middle side of the lower part of a rotating plate, and first mounting blocks are fixedly connected to the middle sides of the front and rear parts of the rotating plate; a balancing weight is fixedly connected between the first mounting blocks, a first motor is fixedly connected to one side of the upper portion of the balancing weight, a rolling wheel is fixedly connected to the output end of the first motor, a second mounting block is fixedly connected to the right side of the middle of the rotating plate, and rotating blocks are fixedly connected to the front side and the rear side of the upper portion of the rotating plate at equal intervals. The base, the rotating column and the rotating plate cooperate, the first motor drives the steel wire rope to adjust the height of the bottom plate, the conveying belt is driven to be adjusted vertically and horizontally, and flexibility is improved; and the cleaning mechanism and the scraper mechanism work together, cleaning is conducted twice through a scraper and a rolling brush driven by a third motor, and the service life of equipment is prolonged.
Owner:泰安市众诚自动化软件有限公司
Traditional Chinese medicine composition and application thereof
PendingCN119587674Agood moisturizing effectfit closelyAntipyreticAnalgesicsRadix Astragali seu HedysariBULK ACTIVE INGREDIENT
The invention discloses a traditional Chinese medicine composition and application thereof. Relates to the technical field. The invention provides application of the traditional Chinese medicine composition, an astragalus membranaceus and cassia twig five-material decoction extracted concentrated solution, an astragalus membranaceus and cassia twig five-material decoction nanoemulsion, an astragalus membranaceus and cassia twig five-material decoction gel plaster and the like. Aiming at the active ingredients of the optimized traditional Chinese medicine composition, the invention develops a nano-emulsion gel plaster preparation for relieving diseases such as muscle pain and rheumatic arthritis. The O / W nano-emulsion technology is used for achieving efficient loading of hydrophilic and hydrophobic functional substances in the radix astragali and cassia twig five-material decoction and the skin penetrating capacity of the hydrophilic and hydrophobic functional substances in the radix astragali and cassia twig five-material decoction. The nanoemulsion is uniformly dispersed in a three-dimensional network structure formed by absorption and swelling of polyacrylic acid, so that the medicine can be slowly and stably released, and the phenomenon of unstable crystallization caused by thermodynamic movement of supersaturated medicine molecules can be hindered. In addition, the gel plaster has a good moisturizing effect and is good in skin attaching feeling and excellent in swelling performance and thixotropic performance.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI +1
Enteritis targeted probiotic delivery system as well as preparation method and application thereof
PendingCN121971653AIncrease productioneffective protectionBacteriaPeptide/protein ingredientsDiseaseInflammatory factors
The invention belongs to the technical field of biological medicine, and discloses an enteritis targeted probiotic delivery system and a preparation method and application thereof, the system comprises: i) a recombinant plasmid for coding an anti-inflammatory functional protein, the plasmid comprising an anti-inflammatory peptide fragment, a surface protein modification and an antibiotic switch; ii) Escherichia coli chassis bacteria which are subjected to genetic engineering modification and have the capability of high yield of outer membrane vesicles; and iii) introducing the recombinant plasmid into the escherichia coli chassis bacterium to obtain a recombinant engineering bacterium. The delivery system disclosed by the invention can target intestinal inflammation parts, deliver anti-inflammatory proteins through the outer membrane vesicles, and specifically release anti-inflammatory factors in an inflammation microenvironment, so that intestinal inflammation response is relieved; according to the present invention, the method can achieve the precise targeting on the intestinal inflammation, can effectively control the remote delivery and the continuous secretion of the anti-inflammatory protein in space and time, has advantages of strong targeting property, lasting effect, small side effect and the like, and provides the new strategy for the safe and efficient treatment of the intestinal inflammation diseases.
Owner:SOUTH CHINA AGRICULTURAL UNIVERSITY
Handcart
ActiveEP4397571A4efficient loadingImprove firmnessSignalling/lighting devicesHand carts with multiple axes
A walk-behind vehicle includes a vehicle body assembly, a driving wheel, a power assembly, a braking assembly, a control assembly and a power supply device. The driving wheel is connected on the vehicle body assembly. The power assembly is mounted in the driving wheel. The braking assembly is arranged on the driving wheel. The control assembly is arranged on the vehicle body assembly and is electrically coupled to the power assembly and the braking assembly. The power supply device is arranged on the vehicle body assembly and is electrically coupled to the power assembly, the braking assembly and the control assembly. The control assembly includes a steering control device, which is electrically connected with the power assembly in the driving wheel on both sides of the vehicle body assembly and configured for controlling a steering of the driving wheel on both sides of the vehicle body assembly.
Owner:GLOBE (JIANGSU) CO LTD
Material taking and loading system capable of being used for electrified railway line
The invention discloses a material taking and truck loading system capable of being used for an electrified railway line, which comprises a movable material taking machine arranged on ground rails on two sides of a goods yard in a sliding manner and capable of taking materials from the goods yard; the transition conveying unit is arranged on a discharging path of the movable material taking machine and can transfer and convey materials. The discharging belt conveyor is arranged on the railway track in parallel and used for receiving materials conveyed by the transition conveying unit. The movable discharging trolley walks on the discharging belt conveyor and is located on one side of the top of the railway track carriage, a contact power grid of the railway track is avoided, the movable discharging trolley is provided with a material receiving end and a double-discharging discharging end, and the position, close to the material receiving end, of the movable discharging trolley is rotationally connected with a turnabout drum. The turnabout drum is connected to a belt of the discharging belt conveyor in a wound mode and changes the moving direction of the belt, materials of the discharging belt conveyor enter the material receiving end after passing through the turnabout drum, the double discharging ends are arranged in parallel at intervals and can be connected with adjacent carriages in the loading process, and the railway line loading device can be suitable for efficient loading of railway lines and is safe and environmentally friendly.
Owner:TIANFU HEAVY IND
Curtain upper beam
ActiveCN224187464UEasy to installEasy to disassembleLight protection screensMechanical engineeringPhysics
Owner:ZHEJIANG YIANO SHADING TECH CO LTD
Electric toothbrush production process
The invention relates to the technical field of electric toothbrushes, in particular to an electric toothbrush production process which comprises the following steps: A, mounting bristles into holes of a fixing plate; b, the fixed plate is subjected to vibration screening treatment; c, carrying out hot melting treatment on the fixed plate subjected to vibration screening treatment, so that the bristles and the fixed plate are bonded to form a brush head; d, the brush head and the brush shell are welded and subjected to laser etching treatment to form a product; e, forming a brush handle with a main machine; f, aligning and assembling the brush handle and the product; wherein the steps from A to D and the step E can be carried out synchronously. After the bristles are inserted into the hole sites of the fixing plate, the postures of the bristles are adjusted through vibration screening treatment, then the bristles are subjected to hot melting treatment, so that the fixing plate and the bristles are bonded, the effect of efficiently and neatly loading the bristles is achieved, and the efficiency is improved.
Owner:DONGGUAN XINCHAOWEI INTELLIGENT TECHNOLOGY CO LTD
Engineered extracellular vesicle for treating central nervous system diseases as well as preparation method and application of engineered extracellular vesicle
PendingCN121950874AIncrease total expressionacross convenienceNervous disorderPeptide/protein ingredientsDiseaseExtracellular vesicle
The invention relates to an engineered extracellular vesicle for treating central nervous system diseases as well as a preparation method and application of the engineered extracellular vesicle. Specifically, the invention provides the expression cassette which has a structure shown as a formula I, a carrier containing the expression cassette, a host cell and extracellular vesicles generated by utilizing the cell. The engineered extracellular vesicles provided by the invention are rich in therapeutic proteins and have excellent blood brain barrier permeability.
Owner:SHAANXI HUIKANG BIO TECH CO LTD +1
Pentatricopeptide repeats (PPR) pipe van loading accessory
ActiveCN222475566USolve the occupancyImprove loading efficiencyPackagingLoading/unloadingMechanical engineeringPentatricopeptide repeat
The utility model discloses a PPR (pentatricopeptide repeats) pipe van loading accessory which comprises a left C-shaped steel and a right C-shaped steel which are used as supporting large arms, three short C-shaped steels in the middle are used as connecting plates, and two groups of winding sling mechanisms are respectively arranged on the left side and the right side to meet the use of quickly retracting and releasing slings; the four winding sling mechanisms are divided into two groups to be arranged on the inner sides of the left C-shaped steel supporting large arm and the right C-shaped steel supporting large arm respectively, and the two winding sling mechanisms on each side are arranged in a mirror symmetry mode and are opposite in movement direction. Each hanging belt winding mechanism comprises two hanging belt guide discs, a clamping pin disc pin shaft, a clamping pin disc, a push-pull pin, a base plate and an electric cylinder. The pipe carrying device is suitable for pipes of other models and types under the same working condition as PPR pipes, improves carrying efficiency, reduces manpower output and manpower cost, and is suitable for large-scale popularization and application.
Owner:SHAANXI WEIXING NEW BUILDING MATERIALS CO LTD
In-vitro culture and separation method of NK cell exosome loaded with PD-1 antibody
ActiveCN119242578Aefficient loadingEfficient expressionCell dissociation methodsBlood/immune system cellsExtracellularMetabolic waste
The invention discloses an in-vitro culture and separation method of an NK cell exosome loaded with a PD-1 antibody, and relates to the technical field of biomedicine, and the in-vitro culture and separation method specifically comprises the following steps: (1) culturing an NK cell; (2) loading a PD-1 antibody; (3) exosome extraction; (4) purifying the exosome; efficient loading of the PD-1 antibody is realized through electroporation, high expression of the antibody in the exosome is ensured, and large-scale production of the exosome is ensured through optimized NK cell culture conditions and an exosome extraction process; inorganic particles are added in cell culture to serve as microcarriers, more attachment points are provided for cells, transmission of nutrient substances and removal of metabolic waste are optimized, the proliferation multiple of the cells is increased, the cell viability is kept, the overall loading efficiency and growth amount of the microcarriers are increased, and therefore growth and proliferation of the NK cells are promoted; the large-scale culture of the cells is realized.
Owner:中乔健工生物科技(广东)有限公司
Nanobody Nb.TB1, engineered plant exosomes, their preparation methods and applications
PendingCN122080199AImprove traversal efficiencyefficient loadingNervous disorderImmunoglobulins against animals/humansNeurological disorderSortase A
This invention discloses a nanobody Nb.TB1, engineered plant exosomes, their preparation methods, and applications, belonging to the field of biomedical technology. The amino acid sequence of the nanobody Nb.TB1 is shown in Seq ID No. 1. Furthermore, this invention proposes a method for preparing engineered plant exosomes, comprising the following steps: S1, extraction of Gastrodia elata exosomes: extracting Gastrodia elata exosomes from Gastrodia elata using an enzymatic method; S2, expression and purification of the blood-brain barrier-crossing nanobody fusion protein with Sortase A ligase; S3, surface modification of the Gastrodia elata exosomes. In addition, this invention also proposes an engineered plant exosome prepared by the above method. Furthermore, this invention proposes the application of the above-mentioned engineered plant exosomes in the preparation of targeted therapeutic drugs for central nervous system diseases. The engineered plant exosomes prepared by this invention exhibit high blood-brain barrier crossing efficiency.
Owner:HUAZHONG AGRI UNIV
Automatic mixing stirrer
ActiveCN224207848Uwell mixedImprove work efficiencyRotating receptacle mixersTransportation and packagingBLENDER/MIXERMechanical engineering
The utility model relates to an automatic mixing stirrer which is characterized in that when metal or villiaumite powder needs to be mixed, the metal or villiaumite powder can be added into a box body from a feeding hole in proportion, the feeding hole is sealed through a sealing door after batching is completed, and then a mixing box is moved to a turnover mechanism, so that the metal or villiaumite powder can be mixed. Supporting legs on the lower portion of the material mixing box are installed in installation grooves in the fixing base, then the lifting assembly is operated, the lifting assembly drives the clamping piece to press the top of the box body, the material mixing box is fixed under cooperation of the clamping piece and the fixing base, then the turnover mechanism is operated, and the turnover mechanism drives the material mixing box to conduct turnover material mixing; the mixing box and the turnover mechanism are arranged in an oblique angle mode, so that when the mixing box is turned over, metal or villiaumite powder in the mixing box can be mixed more evenly, after mixing is completed, the lifting assembly is operated, the clamping piece is moved away from the box body, then the mixing box is taken down from the turnover mechanism to be discharged, and the other mixing box is installed on the turnover mechanism to continue mixing.
Owner:AMC ALUMINUM (CHINA) CO LTD
MODIFIED EXTRACELLULAR VESICLES AND THEIR USES
Owner:CODIAK BIOSCIENCES INC
An implementation method and device of an applet associated with a third-party platform and a medium
ActiveCN116578799Befficient loadingEnergy efficient computingSpecial data processing applicationsProgramming languageThird party
This invention discloses a method, apparatus, and medium for associating a mini-program with a third-party platform. The method includes: receiving a request from a mini-program developer to associate the mini-program with a specified third-party platform; obtaining a third-party platform identifier code from the specified third-party platform; extracting features from the third-party platform identifier code to determine its feature values; and storing the feature values, the third-party platform identifier code, and the mini-program's identifier code in a data table to determine the association relationship between the mini-program and the specified third-party platform. This achieves the technical effect of fast and efficient loading of the mini-program, thereby solving the technical problems in existing technologies, such as page lag, slow loading, and resource waste caused by the need to load a page.
Owner:ZHUHAI FANTAI GEEK TECH CO LTD
A packing tool for slurry pumps
ActiveCN224283032Uefficient loadingAddressing the Risk of DisengagementPump componentsPumpsScrew threadSlurry pump
This utility model discloses a packing tool for a slurry pump, including a fixed shell, a flat shovel, a sealing cap, and a connecting shell. The fixed shell has a rectangular structure and an installation cavity inside. The installation cavity has a through-type structure from top to bottom and an installation groove at the rear end. The flat shovel is installed in the installation cavity, and the sealing cap is fixed in the installation groove by bolts. A connector is located on the left side of the fixed shell, and a connector is installed on the right side of the fixed shell. A connecting shell with a rotatable connection is provided on the connector. Both the connector and the connecting shell have upper and lower sets, and the connecting shell is threadedly connected to the connector. This utility model solves the risk of slipping when packing on a slurry pump, thus allowing for more efficient installation of the packing line into the stuffing box, improving work efficiency. Multiple flat shovels can be assembled and disassembled according to the threaded connection between the connector and the connecting shell, and can be evenly distributed around the shaft according to the bearing thickness, thereby increasing the applicability.
Owner:BAOTOU IRON & STEEL (GROUP) CO LTD
Extracellular vesicle drug delivery system and preparation method and application thereof
ActiveCN116159036Bgood biocompatibilityImprove targetingOrganic active ingredientsAntibacterial agentsExtracellular vesiclePharmaceutical drug
The present invention relates to the field of biomedical technology, and specifically to an extracellular vesicle drug delivery system, a preparation method thereof, and an application thereof. The extracellular vesicle drug delivery system comprises extracellular vesicles, and CircRNA and anti-tuberculosis drugs loaded in the extracellular vesicles. The present invention uses extracellular vesicles as co-carriers of CircRNA and anti-tuberculosis drugs, efficiently loads CircRNA and anti-tuberculosis drugs with anti-tuberculosis immune regulation functions, and then further enhances the targeting of the extracellular vesicle drug delivery system by performing surface targeted modification on the extracellular vesicles. The extracellular vesicle drug delivery system more effectively kills and eliminates Mycobacterium tuberculosis in host cells by combining the anti-tuberculosis immune regulation function of CircRNA and the Mycobacterium tuberculosis inhibitory effect of anti-tuberculosis drugs, thereby providing a new strategy for the development of safe and efficient anti-tuberculosis drugs.
Owner:DONGGUAN SOUTHEAST CENTRAL HOSPITAL (DONGGUAN SOUTHEAST TRADITIONAL CHINESE MEDICINE MEDICAL SERVICE CENTER DONGGUAN FIRST HOSPITAL AFFILIATED TO GUANGDONG MEDICAL UNIVERSITY)
Mine card parking planning method and device and mine card
The invention discloses a parking planning method and device for a mine card and the mine card, and aims to optimize the parking position of the mine card, enable the parking position of the mine card to be safe and guarantee the loading efficiency of an excavator. The parking planning method of the mine card comprises the following steps: acquiring an excavation working face and a travelable area of the mine card based on a target mine scene of mine card work; determining a safe reachable area of the mine truck according to the excavation working face and the travelable area; based on the mechanism characteristics of the excavator, high-quality working space of the excavator is obtained; based on the safe reachable area and the overlapped area of the high-quality working space of the excavator, the parking point of the mine truck is determined; wherein the working performance of the excavator in the high-quality working space is superior to that of the excavator in the non-high-quality working space; and planning a parking scheme of the mine card according to a preset starting point of the mine card and the parking point.
Owner:SANY AUTOMOBILE MFG CO LTD
Glass plate package manufacturing method and manufacturing device
ActiveCN114286788Befficient loadinggood precisionShock-sensitive articlesRigid containersGlass sheetPallet
The manufacturing method of a glass plate package (PB) comprises: a position measuring step, in which a measuring device (25) is used to measure the position of a pallet (P); and a correction step, in which a control device (9) is used to control a loading device (8) in a manner to correct the loading position of a glass plate (G) relative to the pallet (P) based on the position information of the pallet (P) measured in the position measuring step.
Owner:NIPPON ELECTRIC GLASS CO LTD
Pedal control mechanism of safety valve of caterpillar truck and caterpillar truck
ActiveCN224326772Ufast loadingefficient loadingOperating means/releasing devices for valvesServomotor componentsStanding frameVehicle frame
The utility model provides a caterpillar conveyor safety valve's footrest control mechanism and caterpillar conveyor, the footrest control mechanism includes: safety valve, is used for setting in the main frame of caterpillar conveyor, safety valve transition pull rod is used for setting between safety valve and standing frame, the top end of safety valve transition pull rod is used for with safety valve valve rod end articulates and connects, the middle part of safety valve transition pull rod is used for with the main frame of caterpillar conveyor articulates and connects, the bottom end of safety valve transition pull rod is suspended and located one side of standing frame, footrest, sets up in the standing frame of caterpillar conveyor, footrest with standing frame articulates and connects, push -and -pull drive mechanism sets up between footrest and the bottom end of safety valve transition pull rod, push -and -pull drive mechanism under the rotation of footrest pushes the bottom end of safety valve transition pull rod and swings. The application has improved the working stability and control stability of caterpillar conveyor safety valve.
Owner:SHANDONG KEN STONE HEAVY MACHINERY CO LTD
Method and device for performing three-dimensional rendering on large-scale DEM data, medium and program product
PendingCN121962380AHigh precisionImprove adaptability3D-image rendering3D modellingResolution thresholdOriginal data
The invention discloses a method and device for three-dimensional rendering of large DEM data, a medium and a program product, and the method comprises the steps: obtaining original DEM data, converting the original DEM data based on a preset target geographic coordinate system, and obtaining basic raster data; performing iterative resampling on the basic raster data based on a preset down-sampling strategy until raster data generated by resampling meets a preset minimum tile resolution threshold, and obtaining a plurality of layers of raster data; dividing each layer of raster data based on a preset tile size to generate tile data; storing the tile data and the corresponding metadata into a preset database; obtaining a rendering parameter, and calculating an index set and a loading priority of the to-be-loaded tile based on the rendering parameter; matching tile data from a preset database based on the index set, and performing gridding processing on the tile data to generate a terrain geometric object; and rendering the terrain geometric object based on a preset scene to complete visual display.
Owner:SOUTH SURVEYING & MAPPING INSTR
La-CPAN-PEI defluorination material as well as preparation method and application thereof
ActiveCN121797281AAvoid chain segment motionAvoid modifiable problemsOther chemical processesSpecific water treatment objectivesPtru catalystFluoride
The invention discloses a La-CPAN-PEI defluorination material as well as a preparation method and application thereof, and belongs to the technical field of water treatment. The preparation method of the material comprises the following steps: performing heat treatment on polyacrylonitrile fibers in protective gas to obtain cyclized polyacrylonitrile fibers; and dispersing the cyclized polyacrylonitrile fiber, an alkali catalyst, an organic lanthanum source and polyethyleneimine in a degassed alcoholic solution, and carrying out solvothermal reaction to obtain the La-CPAN-PEI defluorination material. According to the method, the pH response characteristic of the PEI chain is utilized, the fluorine ion adsorption process is precisely regulated and controlled, and the process shows the characteristics of acid adsorption and alkali removal and dynamic balance of an intermediate pH region. The material has high adsorption capacity, excellent selectivity and simple and convenient acid-base cyclic regeneration capacity through the synergistic effect of three mechanisms of electrostatic attraction, conformation mass transfer and precipitation immobilization, and has a good application prospect in deep treatment of fluorine-containing wastewater.
Owner:HEFEI INSTITUTE OF PHYSICAL SCIENCE CHINESE ACADEMY OF SCIENCES