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252results about "Tourniquets" patented technology

Wearable monitor for the early detection of internal bleeding events after cardiac catheterization

PendingUS20260157650A1CatheterSensors
A wearable monitor is configured for early detection of internal bleeding events and particularly hematomas after vascular catheterization including cardiac catheterization. The wearable monitor is placed over an access location following the vascular catheterization procedure and the wearable monitor system periodically runs diagnostic test to detect changes in the tissue around the vascular access location. An emitter device may input an emitter input into the tissue and a detector device may then measure the emitter input after it has passed through the tissue, an emitter output. A computer may receive the data from the detector device and operate a program that determines changes in the tissue and in particular, pooling of blood in the tissue. The emitters may be electrodes that input an electromagnetic input, or an ultrasound emitter that inputs ultrasound sound waves, or a Near IR emitter that emits Near IR electromagnetic radiation.
Owner:HEMASENSE INC

A highly effective tourniquet

ActiveCN224269380UTourniquetsMechanical engineeringTourniquet
This utility model provides a high-efficiency tourniquet, relating to the field of tourniquet technology. It includes a tourniquet body, a connecting collar, a first connecting member, a second connecting member, a vertical rod, a first auxiliary member, a second auxiliary member, and a third auxiliary member. By rotating the vertical rod, the first connecting member is coiled around its outer surface. As the first connecting member moves, the first auxiliary member moves closer to the vertical rod. This causes the third auxiliary member to shift, separating the toothed part from the blocking ring. At this point, the tourniquet body, located between the toothed part and the blocking ring, can be pulled, causing it to adhere tightly to the patient's wound. Then, the vertical rod can be released, eliminating the external tension on the third auxiliary member. This causes the toothed part to move back towards the blocking ring, thus preventing further movement of the tourniquet body and effectively stopping bleeding from the wound.
Owner:JIANGXI RUSHANG BIOTECHNOLOGY CO LTD

Multifunctional tourniquet for controlling bleeding in boundary area under field conditions

PendingCN122163276ATourniquetsHuman bodyMuscle contraction
The present application relates to the technical field of tourniquet, in particular to a multifunctional tourniquet for controlling bleeding in the junctional area under field conditions, comprising a tourniquet assembly. The present application ingeniously locks the tourniquet body and the human body limb by setting two groups of anti-skid mechanisms comprising fixing belts, positioning plates, clamping blocks and device sleeves. When the clamping blocks are precisely inserted into the clamping grooves on both sides of the device sleeve under the action of the spring restoring force, a rigid closed structure surrounding the limb is formed. This structure can effectively resist the axial shear force generated by the movement of the wounded, the change of body position or the contraction of limb muscles. At the same time, the linkage system composed of the device sleeve and the positioning belt can disperse the local stress. Even if there is sweat or blood on the surface to cause lubrication, the mechanical self-locking design of the multi-point clamping can also prevent the overall tourniquet from sliding or twisting, so as to maintain constant ring pressure and position in the dynamic jolt environment of field evacuation, greatly reducing the risk of tourniquet failure and secondary bleeding caused by instrument displacement.
Owner:903 HOSPITAL OF THE JOINT LOGISTICS SUPPORT FORCE OF THE PEOPLES LIBERATION ARMY OF CHINA

45-degree oval thoracic curet

The utility model relates to a 45-degree oval thoracic cavity curettage spoon, which belongs to the technical field of medical supplies. The utility model discloses handle and harrow hook are connected as an organic whole, the harrow hook includes the harrow hook main part and the spatula who are connected, the spatula is arranged at the front end of the harrow hook main part, the handle is arranged at the rear end of the harrow hook main part, and the spatula adopts oval long groove type design. The utility model has simple and reasonable structure design, is safe and reliable, convenient to operate, can be applied to single-hole and multi-hole thoracoscope, and satisfies the use demand.
Owner:ZHONGSHAN XIAOLAN PEOPLES HOSPITAL

An endoscopic spine surgery patch

ActiveCN224387531Uavoid running aroundavoid runningSuture equipmentsInternal osteosythesisSpinal columnEndoscopic Procedure
The utility model discloses a kind of endoscope surgery pasting film, it is related to medical supplies technical field, including first film, second film, water baffle and liquid collecting and guiding bag.The bottom surface of first film is used to paste on skin.Second film is located on the top surface of first film, and the accommodating cavity that is formed with upward protrusion between second film and first film.Water baffle is located in accommodating cavity, and the region formed by surrounding water baffle is used to accommodate liquid.Liquid collecting and guiding bag is connected with one side of second film, and the bag opening of liquid collecting and guiding bag is towards the opening of water baffle, so that the liquid in the region formed by surrounding water baffle can flow into liquid collecting and guiding bag.In the process of operation by doctor, water baffle can be resisted by second film with physiological saline and patient's blood and other liquids, that is, water baffle plays a blocking role to liquid, so that liquid in the process of operation all stays in the region formed by surrounding water baffle, avoid the pollution of the surrounding environment of operation area.
Owner:THE FIFTH AFFILIATED HOSPITAL SUN YAT SEN UNIV

Tourniquet

PCT designated stageWO2026127784A1Tourniquets
A tourniquet comprises a sheath, an air bladder disposed inside the sheath, an air supply assembly connected to the air bladder and allowing air to be pumped into the air bladder, a detachable compression element which comprises an upper contact part and a lower connecting part and is designed to interact with the air bladder, and a means for securing the sheath to a person's body, said means being connected to the sheath. The compression element is made of a polymeric material that is resistant to elastic deformation under pressure when the tourniquet is in use. The upper contact part of the compression element is designed so that an attachment can be fastened thereto for applying pressure to a region of the body. The compression element is designed so that the upper contact part can be positioned above a wound, in the region of a blood vessel.
Owner:CHUPRINA YURY GRIGOREVICH

A post- varicose vein surgery wound compression hemostasis device

PendingCN122251087ATourniquetsVaricose vein surgeryVaricose vein
The application discloses a post-varicose vein surgery wound compression hemostasis device, which comprises a device main body for fixing on a limb, a pressure increasing module arranged on the device main body and an anti-reverse mechanism. The pressure increasing module comprises a rotating handle rotatably arranged on the device main body, a pressure push rod with a top end threadedly connected with the rotating handle and a compression pad arranged at the bottom end of the pressure push rod; the pressure push rod is slidably connected with the device main body. When the rotating handle is rotated clockwise, the pressure push rod is driven to move towards the skin side, so that the compression pad applies compression pressure on the wound. The anti-reverse mechanism is connected with the rotating handle and is used for preventing the rotating handle from being rotated counterclockwise, thereby preventing the compression pressure from being released accidentally. The device can accurately and stably maintain the compression pressure on the wound, avoids postoperative rebleeding or hematoma formation caused by pressure attenuation, and has the characteristics of convenient operation, safety and reliability.
Owner:THE SECOND AFFILIATED HOSPITAL ARMY MEDICAL UNIV

Compression hemostat

PendingCN122140319ATourniquetsMechanical engineeringHemostat
The application discloses a compression hemostat, and relates to the technical field of medical devices, and the compression hemostat comprises a pressing device, a fixing part and a temperature adjusting module, the pressing device comprises a pressing part and an adjusting mechanism for adjusting the contact pressure of the pressing part, the pressing device is installed on the fixing part, the fixing part is used for being fixed on a patient, so that the pressing device is kept fixed with the patient's limbs when the pressing device works, and the temperature adjusting module is used for adjusting the temperature of the pressing part, and the temperature adjusting module comprises a display screen used for displaying at least one kind of information in temperature, pressure and bleeding state, through the adjustment of the temperature of the pressing part, the patient can upgrade passive hemostasis to active auxiliary treatment according to the sensitivity and feeling of cold and heat.
Owner:YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE

A multifunctional control device for assisting endoscopic intervention

The application relates to the technical field of medical equipment, in particular to a multifunctional control device for assisting endoscope interventional treatment, which comprises a foot pedal device, a cluster control box, a holding device and a signal line, the cluster control box is connected with the foot pedal device through the signal line, a plurality of holding devices are connected with the cluster control box, a control panel center is installed in the cluster control box, the holding device comprises a fixed base, a sliding push base, a sliding block body, a half-ring supporting body and a buckle cover body, the sliding push base is slidingly installed on the fixed base, a module fixing assembly is arranged at the right end of the fixed base, L-shaped limiting edge plates are symmetrically arranged at the two sides of the sliding push base, the sliding block body is slidingly installed on the sliding push base through the limiting edge plates, the application can make a plurality of endoscope examination operation modules be concentrated together, manual control is completely replaced by foot pedal electric control through mode function switching, and the task amount of hands is reduced.
Owner:JILIN UNIVERSITY

A preoperative assessment-based wrist hemostasis system and method

The application discloses a wrist hemostasis system and method based on preoperative evaluation, and relates to the technical field of intelligent medical treatment, and comprises the following steps: acquiring patient data and corresponding medication data, inputting the patient data into a preset weighted scoring model, and outputting a preoperative bleeding risk level; the patient data comprises platelet count, international normalized ratio (INR), and activated partial thromboplastin time (APTT); according to the preoperative bleeding risk level, setting an individualized compression initial pressure and a basic compression time length; the compression initial pressure is a fixed multiple of systolic pressure, and the compression time length is a matching value in a preset interval; after the hemostasis device is controlled to be boosted to the initial pressure, a stepwise decompression program is executed, the compression pressure is gradually reduced, and a distal PPG signal is synchronously monitored; when the PPG signal is stable and reappears, the corresponding pressure is recorded as a blood flow recovery pressure; while reducing the risk of bleeding and rebleeding, the safety, stability and individual adaptation degree of the wrist hemostasis process are improved.
Owner:SHENZHEN MATERNITY & CHILD HEALTHCARE HOSPITAL

Vertical electric hemostat

ActiveCN224344969UAchieve angle adjustmentSurgical furnitureTourniquets
The utility model relates to the technical field of hemostasis instrument, disclose a vertical electric hemostasis instrument, including base, install the storage frame on the outer wall of base, rotate and install the hemostasis instrument host computer on the top of base, the top of base rotatory installation has the connecting column, the top of connecting column installs the adjusting mechanism of drive hemostasis instrument host computer vertical rotation, the adjusting mechanism includes the mounting bracket, the inside rotatory installation of mounting bracket has the pivot no.
Owner:ANHUI FINAL TECH CO LTD

An appendiceal orifice support device for endoscopic retrograde appendectomy

ActiveCN224387481UEasy to pushshooting stabilitySuture equipmentsInternal osteosythesisAppendix lumenGeneral surgery
The application relates to the field of medical instruments, and provides an appendix orifice supporting device for endoscopic retrograde appendix treatment, which comprises a support head, a support base, an unfolding piece, a first direction line, a second direction line and an opening and closing piece. A channel is arranged on a colonoscope. The support base is arranged around the front end of the colonoscope. The unfolding piece is arranged in at least three groups and is arranged in sequence along the support base. The opening and closing piece is located in the channel and is divided into a pushing end and a connecting end. The pushing end is located outside the colonoscope. When the pushing end is pushed, the connecting end moves along the channel and extends out of the channel. The support head is an elastic structure with expansion characteristics, and the bottom is connected with the connecting end and the unfolding piece. The application has the advantages of conveniently providing support for the appendix orifice and providing the effect of extending a sub-scope into the appendix cavity for shooting, exploration and treatment on the basis of facilitating colonoscope treatment.
Owner:XIAMEN CHANG GUNG MEMORIAL HOSPITAL CO LTD

Arthroscopic approach water leakage prevention device

PendingCN122163334ASuture equipmentsInternal osteosythesisMedicineArticular cavity
The present application relates to a kind of arthroscopic approach water leakage prevention device, including the elastic cover with dome structure, the sealing valve being arranged in the center position of cover and negative pressure suction mechanism, sealing valve has the conical hollow structure extending to base direction and gradually reducing outer diameter, reverse compensation sealing is realized using joint cavity infusion liquid pressure, cover base edge is equipped with flexible sealing skirt, by the negative pressure interface connection external negative pressure source, so that cover and skin form negative pressure sealing space, the device can be connected in series by negative pressure interface multiple occluder, and equipped with detachable guide rod auxiliary coaxial positioning.The present application uses non-insertion type surface adsorption occlusion, effectively solve the space interference and tissue damage problem in multiple tunnel operation, realize the dynamic water stop of pressure self-adaption, with the advantages of simple operation, sealing stable, strong dissection adaptability, can significantly improve the operation visual clarity and maintain joint cavity pressure stability.
Owner:NANJING GENERAL HOSPITAL NANJING MILLITARY COMMAND P L A

Wearable ai-assisted pressure-controlled ischemic preconditioning training device

PendingCN122163275ALavatory sanitorySensorsPhysical medicine and rehabilitationIschemia preconditioning
This invention relates to the field of medical and health device technology, and discloses a wearable AI-assisted pressure-controlled ischemia pretreatment training device, including a support base. A support plate is fixedly connected to the inner side of the support base, and a restraint strap is detachably connected to the inner side of the support plate. Two airbags are installed inside the restraint strap. Two fixed cylinders are fixedly connected to the outer side of the support base. A connecting tube 1 and a connecting tube 2 are sequentially connected to the outer side of each fixed cylinder. The end of the connecting tube 2 away from the fixed cylinder is connected to the interior of the airbags. A movable plate is slidably connected inside the fixed cylinders, and a movable rod is fixedly connected to the outer side of the movable plate. By setting up airbags 1 and 2 and combining them with an AI pretreatment training system, coordinated ischemia and reperfusion training of two target organs (finger and arm) can be achieved. This dual-site training stimulates a stronger anti-ischemic injury protection mechanism in the body, broadening the applicable population and training scenarios of the device.
Owner:BEIJING SPORT UNIV

Adapter device for connecting a surgical instrument and a robotic system for surgery

The invention relates to an adapter device 1 for connecting a surgical instrument 2 to a robotic system incompatible with the surgical instrument 2, comprising an adapter housing 3, a series of first transmission elements 5 for connecting to drives 14 of the robotic system on a side surface of the adapter housing 3, a series of second transmission elements 6 mechanically connected to the first transmission elements 5 for connecting to outputs 7 of the surgical instrument 2, and a mechanical transmission 8 arranged within the adapter housing 3 between at least one of the first transmission elements 5 and at least one of the second transmission elements 6. The invention further relates to a robotic system for surgery with an adapter device 1.
Owner:ARTS GMBH

Negative pressure suction sheath and endoscope assembly

This application provides a negative pressure suction sheath and an endoscope assembly, relating to the field of medical device technology. An ultrasonic transducer is installed on the sheath seat or sheath tube of the negative pressure suction sheath. The output end of the ultrasonic transducer is connected to a metal layer inside the sheath tube. During surgery, if stone fragments cause blockage inside the sheath tube, ultrasonic waves can be generated by activating the ultrasonic transducer. These waves propagate to the metal layer of the sheath tube, where energy is transmitted to the metal layer in the form of mechanical vibration, causing the metal layer to vibrate mechanically, thereby facilitating the smooth removal of the blockage stone fragments.
Owner:HUNAN VATHIN MEDICAL INSTR CO LTD

In-vivo clot meshing structure

ActiveCN224330996UEfficient and quick to retrieveCuts effectively and quicklySuture equipmentsInternal osteosythesisHuman bodyEndoscope
The utility model discloses a kind of in-vivo blood clot cutting net structures, including the outer tube structure being cooperated with endoscope, the middle tube structure being arranged in outer tube structure and being cooperated with outer tube structure, and the inner core structure being arranged in middle tube structure;Wherein, the middle tube structure can be inserted or pulled out along outer tube structure, the inner core structure can be inserted or pulled out along middle tube structure.This application provides a kind of in-vivo blood clot cutting net structure, can be inserted into human body by the channel of endoscope, and can be deployed into adjustable angle's fishing net structure in human body, can effectively and quickly complete the fishing and cutting of large blood clot, and need not repeat extraction and insertion endoscope, that is, improve the cutting efficiency of large blood clot, also avoid the pain that repeat extraction and insertion endoscope brings to patient.
Owner:汪跃

hooked probe under mirror

This utility model discloses a endoscopic hook knife probe, relating to the field of medical device technology. The endoscopic hook knife probe includes a handle, a rod, and a blade. The two ends of the rod are connected to the handle and the blade, respectively. The connection between the blade and the rod can be configured with a bent structure at an angle between 90° and 120°. The blade includes: a cutting edge disposed on both the inner and outer sides of the bent structure, capable of cutting tissue at the surgical site; and a blunt structure located at the front end of the bent structure, shaped as a smooth hemisphere. This endoscopic hook knife probe can be used in combination with endoscopes and other instruments to perform minimally invasive anterior cervical fusion surgery, filling a technological gap in existing domestic surgical techniques. The endoscopic hook knife probe proposed in this application effectively meets the clinical needs for minimally invasive, visualized, safe, and efficient procedures, significantly improving the ease of operation and surgical efficiency.
Owner:DEHONG PREFECTURE PEOPLES HOSPITAL

Radial artery intelligent compression hemostat and control method thereof

ActiveCN115670572BCatheterSensorsArtery punctureRadial artery puncture
The present application belongs to the technical field of radial artery hemostasis device, and particularly relates to a radial artery intelligent compression hemostasis device, which comprises a shell, a pressure sensor, a speed reducer and a compression rod, the pressure sensor and the speed reducer are both arranged in the shell, the fixed end of the pressure sensor is fixedly connected with the shell, the speed reducer is fixedly arranged at the measuring end of the pressure sensor, the output end of the speed reducer is threadedly connected with one end of the compression rod, a guide channel is arranged on the shell, the compression rod is slidingly arranged in the guide channel, the end of the compression rod away from the speed reducer is provided with a pressing plate, the pressing plate is exposed to the shell, a silica gel compression pad is detachably arranged on the pressing plate, a bandage is arranged on the shell, the bandage is used for binding the radial artery intelligent compression hemostasis device on the wrist of a patient, and at this time, the compression pad is pressed on the radial artery puncture point. The hemostasis device avoids long-time compression of the distal end of the radial artery, avoids insufficient pressure from causing bleeding, and most quickly achieves the purpose of radial artery compression hemostasis, and reduces secondary injury and sequelae after compression.
Owner:ZHEJIANG XILINTE PHARM TECH CO LTD

Wearable system to stop the bleeding

PendingEP4753586A1TourniquetsPersonal protection gear
The present invention relates to a system (S) for controlling bleeding comprising a bulletproof vest (1 ) wearable by a subject having an internal face (11 ), which in use faces said subject, and one or more pockets formed in said internal face (11) and arranged in proximity to the shoulders and / or hips of a subject wearing said bulletproof vest (1), at least one wearable passive safety device (3), in contact with said internal face (11) of said bulletproof vest (1), in which said passive safety device (3) is able to expand as a result of an impact and / or an external command, in such a way as to counteract a bleeding of a subject wearing said system (S), at least one hemostatic cuff (2) operatively connected to said bulletproof vest (1) and configured to envelop a portion of a limb of the subject, and to occlude blood flow to said limb following an impact and / or an external command, wherein said passive safety device (3) and said at least one hemostatic cuff (2) are arranged, when not in use, inside said one or more deformable pockets, and wherein said one or more deformable pockets comprise a means for inflating and activating said passive safety device (3) and said at least one hemostatic cuff (2). The present invention also relates to a program for controlling the operation of said system (S).
Owner:VIOLANTE FRANCESCO SAVERIO

Lung segment bronchial catheter

ActiveCN115227930BSuture equipmentsInternal osteosythesisPartial lobectomyThoracic surgery department
The application provides a lung segment bronchus catheter, which comprises a catheter tail end ventilation and suction interface, a cuff inflation device, an outer tube, an inner tube, a front end cuff and a guide end formed by the inner tube; the cuff is annularly arranged on the outer surface of the catheter head, and is in the form of a ring ball wrapped around the inner tube in the inflated state; the cuff inflation interface and the cuff inflation conduit are communicated between the gap between the outer tube and the inner tube at the catheter tail and lead to the cuff; the catheter ventilation and suction interface is communicated with the inner tube and the guide end formed by the inner tube, and a guide wire is arranged in the catheter ventilation and suction interface to form a straight lumen. The catheter can enter the target lung segment or sub-lung segment bronchus through the operation channel of the bronchoscope, the inflated cuff seals the airway cavity around the lung segment bronchus catheter cavity, then the guide wire is pulled out from the lung segment bronchus catheter cavity, the target lung segment or sub-lung segment is inflated through the catheter ventilation and suction interface, so that the anatomical range of the target lung segment or sub-lung segment after ventilation is revealed, the technical problem that a thoracic surgeon cannot accurately identify the anatomical range of the target lung segment in the operation is effectively solved, and the thoracic surgery anatomical partial lobectomy operation is facilitated.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI

Inflatable radial artery compression device with cinch wristband and method of use

Radial artery compression devices are disclosed. Some embodiments include an inflatable chamber and a frame. Also disclosed are securement bands including a securement band having a free end that passes through a portion of the frame. Systems and methods for securing and / or positioning the securement device with one hand are also disclosed.
Owner:MERIT MEDICAL SYSTEMS INC

Locking mechanism and handle for a surgical device with such a locking mechanism

The invention relates to a locking mechanism for locking a mobile element (160) with a base element (140), wherein the mobile element (160) is guided and movable relative to the base element (140), comprising - a locking pin (162) fixed to the mobile element (160) and oriented transversely to the path of movement and - a labyrinth body (22) pivotably mounted on the base element (140) with a recirculating body (223) which can be slid around by the locking pin (162) and which has sliding surfaces extending parallel to the locking pin (162), including a first sliding surface (223-1) and a second sliding surface (223-2), which are at an acute angle to each other facing the mobile element (160) and are connected at their ends away from the acute angle by a concave third sliding surface (223-3), wherein the locking pin (162) and the labyrinth body (22) are designed to interact in such a way that after initial actuation of the mobile element (160) its return movement is blocked and after further actuation it is allowed again. The invention is characterized by two springs (24, 26) acting antagonistically on the labyrinth body (22), whose opposing torques hold the labyrinth body (22) in a predetermined initial position when it is not interacting with the locking pin (162).
Owner:BOWA ELECTRONICS

An endoscope and endoscope surgery system

PendingCN122140303ASuture equipmentsInternal osteosythesisEndoscopic surgeryCatheter
The application provides an endoscope and an endoscope surgery system, and relates to the endoscope equipment field.The endoscope comprises a catheter assembly and a cutting wire assembly.The catheter assembly comprises an insertion tube, the insertion tube has at least two parallel arranged lumen, the at least two parallel arranged lumen comprises an instrument lumen and at least one cutting wire lumen, the tube wall of each cutting wire lumen is provided with a side opening at the part of the distal end of the lumen wall of the insertion tube, the side opening penetrates to the outer wall of the insertion tube, and the side opening is arranged to extend to the distal end.The cutting wire assembly comprises at least one cutting wire, the cutting wire is arranged in the at least one cutting wire lumen, the distal end of the cutting wire is connected with the distal end of the insertion tube, and the part of the cutting wire corresponding to the side opening is a cutting section.The application can relieve the situation that special instruments are frequently replaced in the surgery process, improve the surgery efficiency, reduce the number of used instruments, and is lower in cost.
Owner:ANHUI YOUNG HEARTY MEDICAL APPLIANCE & EQUIP +1

Devices and methods for catheter alignment

A launching catheter for targeting a second vessel from a first vessel includes a catheter including a proximal portion and a distal portion including a needle aperture and a flat rectangular radiopaque marker. The flat rectangular radiopaque marker disappears under fluoroscopy upon rotation to provide information about rotational alignment of the launching catheter. The launching catheter includes a needle configured to extend through the needle aperture. A method of aligning the catheter includes rotating the catheter in a first blood vessel until the marker has a thickness (e.g., minimal thickness) under fluoroscopy. The thickness indicates rotational alignment of the catheter.
Owner:LIMFLOW +1

Magnetic stone extraction basket handle

This invention relates to a magnetic stone retrieval basket handle, belonging to the field of medical device technology. This magnetic stone retrieval basket handle achieves axial movement and circumferential rotation of the basket's core wires through a non-contact transmission method using magnetic coupling between an outer and inner magnet. Combined with the guiding effect of a steel tube, it ensures the smoothness and precision of the basket's opening, tightening, and rotation operations, avoiding the jamming and loosening problems of traditional mechanical transmission. It simplifies the handle's transmission structure, reduces mechanical wear, and extends the handle's service life. Magnetic transmission eliminates the need for threads, drill holes, or other structures on internal transmission components, facilitating cleaning and disinfection, reducing the risk of infection, and improving the stability and safety of intraoperative stone retrieval operations.
Owner:SPULE (ZHUHAI) BIOTECHNOLOGY CO LTD