The present invention provides a dynamic model directed angiography three-dimensional reconstruction method, pertaining to an intersectional field of digital image processing and medicine imaging, for satisfying special requests of auxiliary detection and surgery guidance for cardiovascular disease in clinical medicine. The invention includes steps of angiography image preprocessing, vascellum segmentation, vascellum skeleton and radii extraction, model directed vascellum base element recognition, vascellum matching and vascellum three-dimensional reconstruction. The invention also provides a cardiovascular dynamic model construction method including steps of cardiovascular slice data extraction, cordis static and dynamic model building, and static and dynamic model building. According to the invention, good angiography three-dimensional reconstruction result may be obtained, which effectively assists detection and surgery guidance for cardiovascular disease, thereby satisfying clinical requests.