33 results about "Vascular anatomy" patented technology

The invention discloses a PICC (Peripherally Inserted Central Catheter) tip precise navigation fixing method and system based on electrocardiogram real-time positioning. High-precision positioning and safe fixing of a catheter tip are realized through a multi-modal data fusion and deep learning technology. The method comprises the following steps: collecting intracavity electrocardiosignals (ECG) in real time through a catheter built-in electrode, and obtaining blood vessel wall contact pressure and temperature data in combination with an optical fiber sensor; an improved wavelet threshold algorithm is adopted to dynamically suppress motion artifacts, and P-wave features are enhanced; the preprocessed ECG signals are input into a spatial-temporal feature fused Transformer model, a time attention layer is used for analyzing P-wave time sequence changes, a space attention layer integrates multi-lead space distribution features, and the positioning precision is optimized in combination with preoperative blood vessel anatomical data; the ECG positioning result and the optical fiber sensing data are fused through Kalman filtering, three-dimensional position information of the tip end of the catheter is generated, and real-time navigation is conducted on an augmented reality interface; and when the P wave amplitude reaches a CAJ threshold value, the contact pressure is safe and no abnormal temperature exists, a shape memory alloy (SMA) fixing ring is triggered to contract, and accurate fixing is achieved. The method solves the problems that a traditional method depends on X rays and is poor in anti-interference performance, has the advantages of being free of radiation, high in real-time performance and adaptive to blood vessel deformation, and is suitable for clinical P catheter implantation.

The invention provides a medical image processing method and a medical image processing device, which can pre-construct a three-dimensional target path image in an occluded blood vessel and solve the technical blind area that the dissection path of a far-end blood vessel cannot be developed due to the fact that a contrast agent cannot pass through the occluded blood vessel in traditional DSA radiography. Moreover, the three-dimensional target path image and a three-dimensional angiography image obtained in the operation can be registered and fused based on a preset mark point to obtain a fused image, and the fused image and the two-dimensional perspective image of the focus area of the patient are registered and fused to obtain a fused image. Accurate space alignment and dynamic superposition of the preoperative three-dimensional target path image, the intraoperative three-dimensional angiography image and the intraoperative two-dimensional perspective image are achieved, a whole-process visible accurate space positioning reference is provided for instrument pushing and vascular access selection of an operator, and the accuracy of surgical operation is improved.

The invention discloses a micro-catheter control method for an acute cerebral infarction interventional thrombectomy, which comprises the following steps: a micro-catheter control system acquires current position state information of a micro-catheter, and drives the micro-catheter to move to a target position according to preset parameters; three-dimensional position coordinates of the microcatheter are obtained in real time through an information acquisition module; the signal processing unit compares the actual position of the microcatheter with a preset target position in real time, judges whether the microcatheter reaches the preset position or not, and receives manually input adjustment parameters when it is monitored that the resistance exceeds a threshold value or the position deviates from a path; and the signal processing unit regenerates a control instruction based on the updated parameters, and drives the microcatheter to continuously move according to the corrected parameter constraint. By acquiring the illness state and blood vessel anatomical structure information of a patient, setting the parameters such as the target position and the moving path of the microcatheter and combining the three-dimensional position coordinate information acquired by the position sensor, the microcatheter can be accurately controlled to reach the target position and move according to the preset path.

The imaging apparatus configured to assess and quantify motion associated with an object and, in a specific case of an eye—retinal vascular anatomy and hemodynamics and generate substantially contrast-free maps of retinal blood flow over a wide field-of-view at up to 590 fps and under short exposure durations (>50 μs), is applicable for diagnosis, study, and management of neurodegenerative conditions (i.e. mild cognitive impairment and Alzheimer's disease) and systemic cardiovascular diseases (i.e. athero- and arteriosclerosis, coronary artery occlusion, and hypertension). The apparatus employs a) a set of apertures substantially blocking light, delivered from a source of light to an illumination arm of the apparatus, from impinging onto an axial point of the front surface of the lens of the illumination arm, and b) polarization gating between the illumination and light-collecting arms of the apparatus. In one implementation, the apparatus is configured to allow for irradiation of the object with an optical field a degree of coherence and / or spectral content of which are varied delivered through the same optical train including the set of apertures.

A system for improving the function of a defective heart includes a tubular membrane, a replacement valve, a set of one or more inlets, and a set of one or more outlets. The tubular membrane encompasses (i) a first chamber of the system, shaped to conform to an interior region of a right atrium of the heart, and (ii) a second chamber of the system, shaped to conform to an interior region of a right ventricle of the heart. The replacement valve is configured to separate the first chamber from the second chamber, and has leaflets for providing flow in only one direction. The one or more inlets connect the first chamber with a first portion of cardiovascular anatomy, and the one or more outlets connect the second chamber with a second portion of cardiovascular anatomy.

This invention discloses an automatic liver segmentation method and system based on anatomical prior guidance of vascular flow direction, belonging to the fields of medical image processing, computer-aided diagnosis, computer vision, and artificial intelligence. The method includes acquiring liver medical images and vascular flow direction features, constructing a three-dimensional vascular direction vector field and vascular topology map, and extracting vascular anatomical prior features using a graph convolutional network; enhancing key vascular region features by combining an attention mechanism and fusing them with liver image features; outputting a liver segment probability map through a decoding network; training the model based on cross-entropy loss, boundary alignment loss, and region consistency loss to achieve end-to-end optimization; and finally outputting the liver segmentation result, which can be used for medical image visualization and surgical planning assistance. This invention improves the accuracy, robustness, and anatomical consistency of liver segmentation, and has good clinical application value.

An example method includes receiving ultrasound (US) data from an echocardiogram probe for a region of interest for of the intracardiac transcatheter procedure. The method also includes constructing a three-dimensional (3D) model of the region of interest based on the US data. The 3D model tracks a set of markers, and a marker of the set of markers has a position on the 3D model. The method additionally includes displaying an output image. The output image comprises an output US image of a portion of the region of interest, overlaid with a portion of the 3D model corresponding to the portion of the region of interest. The portion of the 3D model comprises the marker. In some examples, the marker tracks a stationary position such as a rapid pacing position associated with a feature, including while the feature is in motion.

In various examples, a skirt for creating a seal between an implantable vascular device and vascular anatomy of a patient includes a seamless tubular structure. The tubular structure is formed from a textile material. A plurality of protrusions extend radially outwardly from the tubular structure. The protrusions are formed within and integral with the tubular structure. Each protrusion including an initial shape, wherein the protrusions are configured to flatten with pressure applied in a radially inward direction with respect to the tubular structure and recoil with pressure at least partially removed to regain the initial shapes of the protrusions, such that the protrusions conform to the vascular anatomy to create the seal between the implantable vascular device and the vascular anatomy.

Exemplary methods can be used to modify a base part, form battery devices, or form devices with surface modification. Exemplary methods can form at least one junction in a base part, and devices can have at least one material junction therein. Exemplary devices, systems, and methods can deliver a drug to body tissue. Exemplary devices and methods can transmit a signal to, or receive the signal from, cardiovascular anatomy and / or a nervous system. Exemplary devices can interface with body tissue and methods can fixate a device to body tissue. Exemplary methods can use a microneedle device. Exemplary biopsy systems and methods can use a biopsy device, the biopsy device including a first tube and a second tube nested in the first tube. Exemplary devices, systems, and methods can cauterize target tissue within body tissue, ablate the target tissue, map electrical activity in the target tissue, or a combination thereof.

This invention discloses an independent drive and collaborative control method for a double-layer medical catheter, comprising the following steps: drive system configuration; sensing data acquisition; collaborative control model construction; drive command generation; drive execution and dynamic adjustment; and safety protection. This invention achieves high-precision independent drive of the two layers of catheters by configuring independent drive units and multi-dimensional sensing modules for the double-layer catheter. Combined with Kalman filtering and PID control algorithms, the positioning error of the inner catheter is controlled within 0.1mm, and the posture adjustment accuracy of the outer catheter is improved by 40%, significantly outperforming existing technologies. Through variable-parameter PID control and operation intention prediction adjustment, the drive response time is shortened to within 50ms, eliminating the lag defects of traditional control and achieving instant matching between the doctor's operation intention and catheter movement, improving the smoothness of surgical operations. The dynamic collaborative control model built based on reinforcement learning can adaptively adjust the collaborative relationship according to vascular anatomy, lesion location, and real-time load data.

The present application relates to the technical field of medical image processing, in particular to a BAD identification model construction method and a BAD identification method based on a small sample. In the present application, a first data set is first constructed as a training sample for model pre-training through data augmentation, then a simulated lesion conforming to the clinical pathological rule is generated in combination with the vascular anatomy features of the PPA region to obtain a second data set, and the pre-trained model is efficiently fine-tuned using the second data set to significantly improve the model generalization ability under the condition of a small sample. At the same time, the finally constructed BAD identification model can automatically analyze the image features and output a diagnosis result. Moreover, through the two-stage training strategy, the powerful feature extraction capability of the pre-trained model is retained, and the model is well adapted to the BAD diagnosis task through a small amount of parameter adjustment, thereby effectively improving the model performance and generalization ability under the condition of a small sample data.

The invention relates to systems and methods for generating patient-specific 3D anatomical models of cardiac and vascular anatomy for real-time, near-real time, and / or interactive catheter and interventional tool navigation and tracking.

The invention belongs to the technical field of medical diagnosis, and relates to an intravascular lesion precise positioning system based on quantum dot labeling and a method thereof, and the method comprises the following steps: enriching at a vascular wall lesion to form a labeled lesion after targeted combination; generating a blood vessel three-dimensional structure image representing a blood vessel anatomical structure; planning and generating candidate excitation point coordinates in the abnormal region; synchronously collecting a fluorescence signal returned by the environmental response type quantum dot probe, and generating a time sequence fluorescence response sequence; generating focus local structure parameters; calculating and generating a calibrated standard response curve; generating a quantitative lesion activity index representing the lesion danger level through comprehensive calculation; and fusing the quantitative lesion activity indexes corresponding to all the coordinate points and the image of the three-dimensional structure of the blood vessel to generate an integrated three-dimensional quantitative diagnosis report. According to the invention, the problem that the signal attenuation effect causes serious underestimation of the real signal of the deep focus is solved.

COMPUTER-IMPLEMENTED METHOD FOR ESTIMATING THE FRACTION OF CORONARY RESERVE FLOW, SYSTEM Method for estimating the fraction of coronary reserve flow (FFR) of a vessel comprising: Acquisition (ACQ1) of a first image from an imaging system; Extraction (EXT1) of a first set of data (ENS1) defining anatomical descriptors of a first vessel; Acquisition (ACQ2) of a second set of data (ENS2) comprising at least the heart rate, systolic pressure and myocardial mass;Generation (GEN1) of an output (S1) defining a prediction of a quantity of coronary flow reserve fraction (FFR) by means of the execution of a first machine learning model (MLA1) to produce an output (S1), said first machine learning model (MLA1) implementing a parameterizable loss function including at least one first factor modeling at least one parameterized physical constraint optimized during the training of said model (MLA1), said parameterized physical constraint resulting in particular from a numerical model of hemodynamic equations (MOD1). Figure for the abstract: Fig.5;

The invention provides a branch stent system for reconstructing a visceral artery, and relates to the technical field of vascular intervention medical instruments, the branch stent system comprises a main stent module, the main stent module is provided with a side hole structure, and the side hole structure adaptively adjusts the size of an interface according to the diameter of a branch blood vessel; the branch support module is provided with a connecting structure, and the branch support module and the side hole structure form a connecting channel; and the conveying module comprises a conveying catheter and a release mechanism, and the conveying catheter bears and conveys the branch stent module. According to the branch stent system for reconstructing the visceral artery, accurate butt joint of the branch stent and the main stent is ensured by adjusting the size of the connector in a self-adaptive mode and adjusting the implanting angle and the releasing position in real time, the problems of deviation, untight attachment and the like caused by blood vessel anatomy difference in the prior art are solved, and the safety and the success rate of an operation are improved.

Potential treatment is planned by retrieving three-dimensional data including vascular anatomy and patient vasculature. Generating a post-treatment hemodynamic model based on a patient vasculature, the patient vasculature being modified based on a proposed treatment applicable to the patient vasculature; at least one lesion of the patient vasculature is introduced or enlarged in the post-treatment hemodynamic model to create a long-term hemodynamic model. Blood flow is simulated in a long-term hemodynamic model. A predicted physiological impact of the proposed treatment is generated based on the long-term hemodynamic model.

An angiogram is a study of blood vessels where an angiographic chemical contrast agent is injected while a sequence of images (typically x-rays) are obtained. The contrast pattern on the sequence of images provides information about the vascular anatomy and physiology. The discovery that contrast in blood vessels varies at cardiac frequency in magnitude and phase, which may be visualized as a spatiotemporal reconstruction of cardiac frequency angiographic phenomena, enables a set of processes for increasing the signal to noise ratio or equivalently the informational content of an angiogram. In this invention, the organization of cardiac frequency magnitude and phase enables equivalent information on anatomy and physiology to be obtained with less dose of injected chemical contrast agent, less x-ray dose, and / or less navigation of the injecting catheter within blood vessels. The cardiac frequency magnitude and phase is organized so that the arterial and venous subsystems of circulation have coherence at cardiac frequency. This enables processes for diagnosing deficits of circulation that involve alterations in the transit of blood from the arterial to the venous subsystems of circulation. Furthermore, the discovery of cardiac frequency magnitude and phase organization enables the design and manufacture of lighter and more portable angiography equipment.

A stent graft apparatus for endovascular treatment of aortic diseases includes a balloon-expandable section and a self-expanding section connected by radial sutures to form a unitary device. The balloon-expandable section comprises a metallic framework configured for deployment via balloon inflation and includes a plurality of radially equidistant radiopaque markers for fluoroscopic visualization. The self-expanding section comprises a shape-memory material configured to exert continuous radial force upon release. The connected sections are sequentially deployed through a catheter-based delivery system, allowing the balloon-expandable section to anchor the graft precisely at the treatment site before the self-expanding section is released to conform to the vessel anatomy. This configuration facilitates both accurate positioning and anatomical adaptability, reducing the risk of migration and improving fixation in complex aortic regions. The apparatus may be used to treat aneurysms, dissections, or injuries in various segments of the aorta.

The invention relates to the technical field of medical instruments, and particularly discloses an adjustable bending sheathing canal system. In order to solve the problem that an operator is forced to replace sheathing canals of different specifications midway, the hemostasis device comprises a handle, a sheathing canal and a hemostasis valve assembly, the sheathing canal is provided with a fixed section and an adjustable bending section, a first bending adjusting ring and a second bending adjusting ring are arranged in the adjustable bending section at intervals, a first bending adjusting wire and a second bending adjusting wire are arranged in the sheathing canal in a penetrating mode, the first bending adjusting wire is connected with the first bending adjusting ring, and the second bending adjusting wire is connected with the second bending adjusting ring. The second bending adjusting wire is connected with the second bending adjusting ring, an adjusting assembly is arranged in the handle and comprises a first driving block and a second driving block, and the first driving block can pull the first bending adjusting wire to enable the adjustable bending section to bend with a first curvature radius; the second driving block can pull the second bending adjusting wire to enable the adjustable bending section to bend with a second curvature radius, and the first curvature radius is different from the second curvature radius. Different bending modes can be selected according to the anatomical form of the blood vessel without replacing instruments.

A vascular access guidance platform provides enhanced visualization and accuracy for medical procedures through an integrated extended reality system. The platform comprises an extended reality visualization system configured to display three-dimensional holograms overlaid on patient anatomy, a registration and tracking system for spatial alignment between virtual and physical anatomy, multiple imaging sensors including infrared cameras and ultrasound devices, and a processing system with coordinate transformation algorithms. The system captures anatomical imaging data, generates augmented representations of vascular anatomy, and aligns these representations with physical patient anatomy using registration techniques including optical markers, spatial mapping, and bony landmark registration. The platform maintains real-time tracking capabilities throughout procedures, accommodating patient movement and practitioner repositioning. Applications include intravenous therapy, hemodialysis access, and blood sampling procedures.

The invention relates to systems and methods for generating patient-specific 3D anatomical models of cardiac and vascular anatomy for real-time, near-real time, and / or interactive catheter and interventional tool navigation and tracking.

The present invention is entitled "Pressure Release Feature for Flushable RF Balloon Catheter". An apparatus includes a catheter shaft assembly and an end effector positioned at a distal end of the catheter shaft assembly. The end effector includes a balloon, one or more electrodes positioned on the balloon, and a tip assembly positioned at a distal end of the balloon. The balloon defines an interior configured to receive fluid to inflate the balloon. The balloon is sized and configured to fit within a cardiovascular anatomy. The tip assembly includes a pressure release valve configured to transition between a sealed state and a pressure release state. In the sealed state, the pressure release valve is configured to prevent fluid from leaking out of the interior of the balloon via the pressure release valve. In the pressure release state, the pressure release valve is configured to provide a path for fluid to leak from the interior of the balloon via the pressure release valve.

The outcome of the treatment applied to the treatment of the blood vessel is evaluated by retrieving three-dimensional data including the blood vessel anatomy and the patient vasculature. A post-treatment hemodynamic model is then generated based on the treatment of the vascular anatomy applied to the three-dimensional data. At least one lesion is introduced and expanded to the patient vasculature in the post-treatment hemodynamic model to create a long-term hemodynamic model, and blood flow is simulated in the long-term hemodynamic model. A predicted physiological state of the patient vasculature is generated based on the long-term hemodynamic model.

The invention discloses an elbow balloon device and method, and belongs to the technical field of medical instruments. The device comprises a double-cavity core tube, a balloon body, a nodule transition section, a balloon conical head, a developing ring and a constant-pressure filling device. The balloon body is formed by arranging large-curvature and small-curvature wave-shaped balloon nodules in a non-axisymmetric mode, and the balloon is automatically bent towards the inner side through differential deformation of the outer sides and the inner sides of the nodules when the nodules are filled. Circular arc transition sections are adopted among the nodes to disperse stress and allow elastic deformation; the head of the balloon is conical so as to improve the trafficability; the large and small nodules have the same wave curve radius, but the middle sections have different lengths, and balloon forms with various bending curvatures are formed through permutation and combination of the large and small nodules so as to adapt to different blood vessel anatomical structures. The invention further provides a using method of the device, the positioning precision, the fitting stability and the operation safety of the balloon in the bent blood vessel can be remarkably improved, and the blood vessel injury risk and the operation complexity are effectively reduced.

To provide an EP mapping within the heart or other cardiovascular anatomical structures within a patient.SOLUTION: An apparatus includes a shaft and an end effector at a distal end of the shaft. The end effector is sized to fit in an anatomical passageway within a subject's cardiovascular system. The end effector includes at least one electrode pair that is configured to contact cardiovascular tissue and thereby pick up electrocardiogram signals. Each electrode pair includes first and second electrodes spaced along a longitudinal axis by a gap area located between the electrodes. The gap area has a gap length with respect to the longitudinal axis. A length of one of the electrodes along the longitudinal axis is equal to or greater than the gap length. A ratio of an area defined by the gap area to one electrode area is equal to or less than one.SELECTED DRAWING: None

A vascular access guidance platform (100) provides enhanced visualization and accuracy for medical procedures through an integrated extended reality system. The platform (100) comprises an extended reality visualization system (102) configured to display three-dimensional holograms overlaid on patient anatomy, a registration and tracking system (104) for spatial alignment between virtual and physical anatomy, multiple imaging sensors (110) including infrared cameras and ultrasound devices, and a processing system (106) with coordinate transformation algorithms. The system captures anatomical imaging data, generates augmented representations of vascular anatomy, and aligns these representations with physical patient anatomy using registration techniques including optical markers, spatial mapping, and bony landmark registration. The registration and tracking system (104) utilizes registration sensors (112) and registration targets (114) positioned at predetermined anatomical locations. The platform (100) maintains real-time tracking capabilities throughout procedures, accommodating patient movement and practitioner repositioning. Applications include intravenous therapy, hemodialysis access, and blood sampling procedures.

This application discloses a covered stent comprising multiple first annular structures and multiple second annular structures distributed axially. The surface of each first annular structure is covered and connected to form a covered segment, exhibiting good flexibility and adaptability to complex vascular anatomy. The axial ends of the second annular structures are provided with winding rings, and adjacent second annular structures are interlocked via these winding rings to form a distal stent segment. This structure effectively resists axial shortening and provides stable distal anchoring. The first annular structure at the end of the covered segment and the second annular structure at the beginning of the distal stent segment are also interlocked via winding rings, achieving a reliable connection between the two segments. A third annular structure may also be provided in the distal stent segment to enhance connection stability. Through a zoned design, this application ensures overall stent flexibility and adherence to the vessel wall while extending the distal anchoring area and maintaining unobstructed branch blood flow, significantly improving the clinical efficacy of endovascular repair of branch vessels.

Embodiments include a method for processing images to determine cardiovascular information. The method may include receiving medical imaging data of a patient and segmenting a plurality of computational model candidates for an anatomical model of a vessel including a stenosis region. Segmenting may include generating the plurality of computational model candidates, determining one or more candidate collocation points, assigning a refinement criterion to each collocation point, freezing each collocation point based on whether a termination criterion is met, and repeating until all collocation points are frozen. The method may further include computing one or more pieces of cardiovascular information for the stenosis region in each computational model candidate, determining whether a variation among values meets a threshold associated with a clinical decision regarding the stenosis region, and outputting images, indicators, reports, or simulations indicating information relating to the cardiovascular information.

This application relates to a delivery assembly and delivery system. The inner catheter is provided with a connecting structure, which includes at least two connecting parts. An outer catheter is movably sleeved outside the inner catheter. A stent-accommodating space is formed between the inner wall of the outer catheter and the outer wall of the inner catheter to accommodate the target stent. The stent-accommodating space is used to accommodate the target stent. A binding structure includes at least two binding threads for binding the target stent. Each binding thread is detachably connected to a connecting part of the connecting structure. Considering the differences in vascular anatomy among individuals, and because the proximal insertion window of the main stent of the target stent is adjustable, and the position of the branch stent relative to the branch vessel is adjustable, the probability of interference between the branch device and the main stent during delivery of branch devices can be effectively reduced, avoiding risks such as deformation, displacement, or kinking of the main stent.