355results about How to "Achieve healing" patented technology

The invention relates to a bone repair porous bracket, which comprises a substrate with a bionic porous structure and growth factor controlled-release microspheres, wherein the growth factor controlled-release microspheres are adsorbed into gaps of the bionic porous structure on the substrate or are dispersed into the substrate by being uniformly mixed with substrate raw material in a substrate forming process. The invention further provides a rapid forming method for the bone repair porous bracket. The method comprises the following steps of: preparing growth factor controlled-release microspheres; forming a substrate; and adsorbing. The invention further provides another rapid forming method for the bone repairing porous bracket. The method comprises a step for preparing growth factor controlled-release microspheres and a step for forming a substrate. The growth factor controlled-release microspheres are introduced into the bracket, bone growth can be induced under the action of the controlled release of growth factors, and inward bone tissue growth is facilitated through a porous structure formed by degradation of the controlled-release microspheres, so that bone tissue regeneration repair is achieved, and bone healing is facilitated effectively. Three-dimensional printing is performed by adding controlled-release microspheres and adopting a rapid forming technology, and a forming process is simple and rapid.

The invention discloses a multifunctional comprehensive treatment platform, comprising a main machine (1), an articulated arm (2) and a treatment head (3), wherein one end of the articulated arm (2) is connected with the top of the main machine (1), the other end of the articulated arm (2) is provided with the treatment head (3), and the treatment head (3) is a UVB (ultraviolet b) treatment head, or a UVA1 (ultraviolet a1) treatment head, or a high-energy red light treatment head, or an integrated optical source treatment head, or an onychomycosis treatment module or a laser anti-obesity treatment head. The platform uses a rotation fixing device to install and fix different treatment heads with various purposes and has the advantages that on one hand, the disassembly and the assembly are convenient, the connection is reliable, and the replacing is convenient and fast; and on the other hand, the function that one main machine can be equipped with various treatment heads with different functions, the treatment field is wide, a great deal of space is saved for the placement of equipment, and the cost of a hospital or a beauty institution is greatly reduced.

The invention provides lactobacillus gasseri and application thereof for preparing vaginal bacteriostatic drugs. The lactobacillus gasseri is collected in China General Microbiological Culture Collection Center, and has a collection number of CGMCC No. 14109. Study of metabolic performance of the lactobacillus gasseri discovers that, compared with ordinary lactobacillus gasseri, the strain has high lactic acid and hydrogen peroxide production capacity, is excellent in bacteriostatic ability of pathogenic bacteria, and also has outstanding vaginal epithelial cell adhesion ability. Based on theprevious discovered novel properties, the invention further provides application of the lactobacillus gasseri in preparation of vaginal bacteriostatic drugs, so that treatment of multiple bacterial vaginal diseases can be realized. The bacterium agent disclosed by the invention has obvious effects on the bacterial vaginal diseases and is safe, non-toxic, excellent in stability and capable of beingpreserved for a long time. The invention further relates to application of the lactobacillus gasseri in medicines for preventing and/or treating gynecological diseases.

The invention relates to the technical field of medicines, in particular to a novel electret microneedle transdermal drug delivery system. The system comprises an isolation layer and a drug-containing pressure-sensitive adhesive layer arranged on the inner side of the isolation layer, wherein an electret layer made from an electret material is arranged on the outer side of the isolation layer; a controlled-release membrane layer is arranged on the inner side of the drug-containing pressure-sensitive adhesive layer; the electret layer, the isolation layer, the drug-containing pressure-sensitive adhesive layer and the controlled-release membrane layer are arranged in sequence from outside to inside to form a reservoir type patch; a microneedle array layer is arranged on the inner side of the reservoir type patch and comprises a microneedle array formed by a plurality of microneedles; each microneedle is 20-50 microns in diameter; and the spacing between every two adjacent microneedles is 1-1.5mm. According to the system, a drug can conveniently penetrate the skin by optimizing microneedle structure and arrangement; and when the system is used, the microneedles act on the skin firstly, the drug quickly penetrates the skin through the needle holes of the microneedles, and the electret layer accelerates drug penetration to achieve a treatment effect.

The invention a bio-medical and beauty-treatment photodynamic flexible fiber fabric, and belongs to the technical field of fabrics. The fiber fabric comprises an adjustable light source, a fiber bundle and a fiber constrictor, the adjustable light source is connected with the fiber bundle and the fiber constrictor, and the fiber constrictor is connected with flexible fibers; and the flexible fibers are braided into the fiber fabric directly, or arranged on a substrate of another flexible fabric. According to the invention, the problems in accurate control for the light dosage, light wavelength and specific irradiation area of illumination in photodynamic treatment are solved, and the photodynamic flexible fiber fabric is portable, and can be used to realize treatment at home or during movement independent of specific places as a hospital.

Provided are an elastic thread setting method in an endoloop and an elastic thread endoloop. The elastic thread setting method comprises the steps that one or more elastic threads are arranged along the outer wall of an endoloop spearhead, one or more threading holes is formed in the outer wall of the front end of the spearhead, the front ends of the elastic threads penetrate into the corresponding second ports of the threading holes, penetrate through the threading holes and penetrate out of the corresponding first ports of the threading holes, elastic thread loops are formed in a slipknot mode, the loops are reversely arranged on the outer wall of the front end of the spearhead in a sleeving mode, and the pore diameter of each threading hole is larger than the diameter of the corresponding elastic thread and smaller than the diameter of the knot point of the corresponding slipknot; when the tail ends of the elastic threads are tightened to make the loops get away from the pipe orifice of the spearhead and the knot points of the slipknots are tightened to the first pores, the first pores are taken as acting points, and the elastic threads are continuously tightened to make the pore diameters of the elastic thread loops gradually shortened. The invention further discloses the elastic thread endoloop using the setting method, the structure is simple, operation is convenient, an operation can be completed by one person, misoperation can be avoided, the wound surface of target tissues after the operation is extremely small, and postoperative complications and the probability of bleeding can be reduced.

The invention provides lactobacillus plantarum and application thereof in preparing vagina antibacterial medicine. The lactobacillus plantarum is preserved in China General Microbiological Culture Collection Center (CGMCC), and a preservation number of the lactobacillus plantarum is CGMCC No.14111. Research on metabolic performance of the lactobacillus plantarum finds that compared with ordinary lactobacillus plantarum, the lactobacillus plantarum has stronger lactic acid production capacity, very strong hydrogen peroxide generation capacity and very strong bacteriostatic ability on pathogenic bacteria; meanwhile, the lactobacillus plantarum has outstanding vaginal epithelial cell adhesive capacity. Based on newly-found characters, the invention determines new application of the lactobacillus plantarum in preparing the vagina antibacterial medicine. The lactobacillus plantarum can achieve treatment on varieties of bacterial vaginal diseases. The lactobacillus plantarum disclosed by the invention has obvious effect on bacterial vaginal diseases, safety, no toxicity and good stability and can be stored for a long time. The invention further relates to application of the lactobacillus plantarum in medicines for preventing and/or treating gynecological diseases.

The invention discloses an intelligent electric acupuncture apparatus, an intelligent terminal and an amplifying circuit of the intelligent electric acupuncture apparatus, and relates to the technical field of traditional Chinese medicine diagnosis devices. The intelligent electric acupuncture apparatus comprises the intelligent terminal, a signal amplifier and an electric acupuncture needle, wherein the intelligent terminal is used for generating electric acupuncture stimulation signals, the signal amplifier is electrically connected with the intelligent terminal, the electric acupuncture needle is electrically connected with an output electrode of the signal amplifier, the signal amplifier receives the electric acupuncture simulation signals from the intelligent terminal, amplifies the electric acupuncture simulation signals and then outputs the amplified electric acupuncture simulation signals to the electric acupuncture needle through the electrode. According to the electric acupuncture apparatus, the electric acupuncture simulation signals are generated through a smart phone, output to the signal amplifier through a data line and then output to an acupuncture point through a wire. Compared with an existing electric acupuncture apparatus, the electric acupuncture apparatus mainly has the advantages that the signals are diversified and more stable, the treatment information storage function is added, a data transmission module is added so that the cloud analysis function can be conveniently achieved, treatment parameters can be read through one key so that workloads on doctors can be reduced, the amplitude is automatically regulated and increased in the treatment process, and the acupuncture point adaptability is lowered.

The invention discloses an elastic thread ligation device and an elastic thread setting method; a gun head comprises a gun head body, a pull rod mount, a gun head sleeve, an elastic thread pull rod, and a gun head fixing sleeve; the outer wall of the gun head of the ligation device is provided with at least one elastic thread and a corresponding traction line, and the two penetrate one thread hole; the front end of the elastic thread forms a slipknot bail sleeved on the gun head fixing sleeve, and is hooked backwards on a hook; the front end of the traction line is connected with the elastic thread; when the elastic thread is released from the hook, the traction line and the elastic thread are simultaneously drawn, so the bail of the elastic thread and the traction line can leave the gun head; the elastic thread is continuously pulled, the thread hole on the gun head fixing sleeve can press the slipknot on the elastic thread bail; a bail hole diameter of the elastic thread can be reduced under the effect of two opposite forces. The elastic thread ligation device is simple in structure, convenient in operation, so operation can be completed by one person with no maloperation; postoperation wound surface of a target organ is very small, thus reducing postoperation complications and hemorrhagic rate.

The invention relates to the fields of life science and medicine. In particular, the invention relates to cancer therapy. More particularly, the present invention relates to oncolytic adenoviral vectors and cells and pharmaceutical compositions comprising said vectors. The invention also relates to the use of said vector in the manufacture of a medicament for the treatment of cancer in a subject, and to methods of treating cancer in a subject. In addition, the present invention relates to methods of producing GM-CSF in cells and increasing tumor-specific immune responses in subjects, and to the use of the oncolytic adenoviral vectors of the present invention for producing GM-CSF in cells and in subjects Use to increase tumor-specific immune response in patients.

The invention provides a setting method of an elastic thread in an ejection type ligation device and an elastic thread ligation device. The setting method of the elastic thread comprises steps as follows: a loop is formed by the front end of the elastic thread in a slipknot form, the loop is arranged in a loop push piece at the front end of a gun head in a sleeving manner, a slipknot of the loop is clamped outside a thread clamping groove in the front end of the loop push piece, the elastic thread is arranged in the thread clamping groove, and the tail end of the elastic thread is finally clamped into a clamping groove in a gun handle and fixed in a direction of a gun barrel; the loop push piece is propped against an infected part, when an ejection block drives the loop push piece to move forwards, the loop is enabled to be separated from the loop push piece and is arranged on the infected part in a sleeving manner, the tail end of the elastic thread is taken down and tightened, the slipknot of the loop is propped by the thread clamping groove of the loop push piece, and the elastic thread is continuously tightened, so that the pore diameter of the loop of the elastic thread is reduced gradually. The invention further provides an ejection type elastic thread ligation device adopting the method. The ejection type elastic thread ligation device is simple in structure, convenient to operate, accurate in operation and applicable to treatment of hemorrhoids and other anorectal diseases, a wound surface of postoperative target tissue is small, and the probability of postoperative complications and hemorrhage can be reduced.

The invention provides lactobacillus reuteri and an application of the lactobacillus reuteri in preparing a vaginal antibacterial drug. The lactobacillus reuteri is collected in China General Microbiological Culture Collection Center with a collection number of CGMCC No. (China General Microbiological Culture Collection Center number) 14110. A study of metabolic performance of the lactobacillus reuteri finds that the strain has better lactic acid production capacity, very strong hydrogen peroxide generation capacity, very strong antibacterial capacity on pathogenic bacteria and excellent vaginal epithelial cell adhesive capacity compared with the common lactobacillus reuteri. Based on the above novel properties found, the novel application of the lactobacillus reuteri in preparing the vaginal antibacterial drug is determined, and treatment of multiple bacterial vaginal diseases can be achieved. The lactobacillus reuteri has a significant effect on the bacterial vaginal diseases, is safe, nontoxic and good in stability and can be stored for a long term. The invention further relates to an application of the lactobacillus reuteri in drugs for preventing and/or treating gynecological diseases.

The invention discloses a long bone fracture repositioning device, which comprises a proximal end support frame, a distal end support frame, quick drawing extension rods, steel needle fixing clamps and steel needles, wherein the quick drawing extension rods are connected between the proximal end support frame and the distal end support frame, the steel needle fixing clamps are connected to the proximal end support frame and the distal end support frame, the steel needles are clamped by the steel needle fixing clamps, the proximal end support frame and the distal end support frame are same in structure and respectively comprise a transverse chute type repositioning slide plate and two fixed gliding hole plates which are connected to the chute type repositioning slide plate, one surface of each chute type repositioning slide plate is provided with a transverse guide sliding chute, a transverse guide long hole is formed between the bottom of the guide sliding chute and the other surface of the chute type repositioning slide plate, the fixed gliding hole plates are provided with holes for connecting the steel needle fixing clamps, the fixed gliding hole plates are further provided with positioning bulges which are matched with the guide sliding chutes and can slide along the guide sliding chutes. The long bone fracture repositioning device disclosed by the invention is simple in structure, the minimally invasive idea is enhanced, the excellent rate of repositioning is improved, and requirements of fracture repositioning and various malformation correcting can be met to the maximum extent.

The invention provides lactobacillus rhamnosus and application thereof to preparation of a vaginal antibacterial medicine. The lactobacillus rhamnosus is preserved in China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.14184. According to research on the metabolic performance of the lactobacillus rhamnosus, compared with the common lactobacillusrhamnosus, the lactobacillus rhamnosus has higher production capacity of lactic acid and hydrogen peroxide, has higher antibacterial capability on pathogenic bacteria and has prominent vagina epithelial cell adhesion capacity. Based on the above discovered new performance, the new application of the lactobacillus rhamnosus to preparation of the vaginal antibacterial medicine is determined, and various bacterial vaginal diseases can be treated. The lactobacillus rhamnosus has remarkable effect on the bacterial vaginal diseases, is safe, non-toxic and high in stability and can be stored for a long time. The invention also relates to application of the lactobacillus rhamnosus to medicines for preventing and/or treating gynecological diseases.

Gel for preventing and treating gynecological inflammation is disclosed. Raw materials for preparation active components of the gel are composed of hydroxyethyl cellulose, phellodendron, common cnidium fruit, stemona, matrine, chlorhexidine acetate, menthol and borneol. By combining Chinese herbal medicines and chemical medicines for synergism, the gel has effects of rapidly inhibiting and killing pathogenic microorganisms such as staphylococcus aureus, mold, pseudomonas aeruginosa and the like, and has remarkable curative effects on chronic gynecological inflammations such as cervical erosion, leukorrhea with reddish discharge, trichomonas vaginitis and vaginal fungal infection, etc.

The invention relates to a plant health care product for preventing and treating gout, which comprises hawthorn leaves or hawthorn leaves added with auxiliary materials such as one or more of lotus leaves, root of kudzu vine, gastrodia elata, hawthorn branch, folium cortex eucommiae, gynostemma pentaphylla, Eucommia ulmoides, pericarpium citri reticulatae, selfheal and Pu'er tea. The plant health care product provided by the invention can be taken directly after being soaked with water, has significant effect to relieve gout, and has health care and auxiliary effects of reducing blood lipid and blood pressure and the like.

The invention relates to a pulse magnetic far infrared radiation composite energy therapeutic instrument with shifted dual-path outputting polarity, which effectively overcomes the shortages of the existing therapeutic instrument and realizes disease treatment by acupuncture points. The structure of the composite energy therapeutic instrument is characterized in that the energy output end of a control part is connected with the input end of an energy emitter by an energy output lead; the control part consists of a box body and a control circuit which is arranged in the box body; the side wall of the box body is provided with pulse magnetic output polarity switch and an energy output lead; the upper cover of the box body is provided with a time adjusting button, a starting button, an energy adjusting and power supply switch; the energy emitter is composed of a shell, a tank-shaped magnetic core which is arranged in the shell, and an insulated lacquering electrifying coil which is sheathed on a magnetic column arranged in the internal chamber of the magnetic core; an energy disc is arranged on the energy emitter; a temperature control switch is arranged in the shell of the energy emitter closely to the external wall of a tank-shaped magnetic core pouring box; the control wire of the temperature control switch is connected in parallel with a resistance wire and is connected with the energy output end of the control part by the the energy output lead. The pulse magnetic far infrared radiation composite energy therapeutic instrument has novel and unique structure and huge economic and social benefits.

The invention provides a single-component healing capsule and self-healing concrete. The single-component healing capsule provided by the invention comprises a capsule wall, a plugging material plugged at the opening of the capsule wall and a single-component healer plugged in the capsule wall, wherein the single-component healer comprises polyurethane and diluter. The single-component healing capsule provided by the invention takes a mixture of polyurethane and diluter as the healer, and the intermolecular action force of the polyurethane is changed through dilution of the diluter, so that the healer has favorable flowability, and the healer can flow evenly in a crack and be solidified and cemented within certain time after the capsule is ruptured. Experimental results indicate that the healer can be uniformly released into the crack after the single-component healing capsule is ruptured; crack healing is realized through cementation with concrete; and the healing efficiency can be up to 32.2% one day after two capsules are ruptured, the healing efficiency can be up to 77.6% two days after two capsules are ruptured, and the healing efficiency can be up to 75.2% three days after two capsules are ruptured.

The invention discloses DRD1 protein and an application of agonists of DRD1 protein in preparation of medicine for treating related inflammatory diseases of NLRP3 inflammasome. Under the action of endogenous agonist dopamine, the protein induces degradation of NLRP3 protein which is an important component of inflammasome and has the function of inhibiting maturity and secretion of inflammatory factors such as IL-1 beta and the like, so that activation of NLRP3 inflammasome is inhibited. According to the invention, the application of the DRD1 protein serving as a target point of related inflammatory diseases, such as peripheral nervous system inflammation and central nervous system inflammation, of NLRP3 inflammasome is provided, and the DRD1 protein can be used for screening and developing medicine for the related inflammatory diseases of NLRP3 inflammasome; and the artificially synthesized agonists A-68930, (+/-)-SKF-38393hydrocholride, SKF89626 and 6-Chloro-PB hydrobromide of the DRD1 protein are further provided and have anti-inflammatory functions, and original ideas and theoretical support are provided for preparation of anti-inflammatory medicine and treatment of the inflammatory diseases by the agonists and active ingredients of the agonists.

The invention discloses a talipes equines orthosis. The talipes equines orthosis consists of a bone fixation support, a steel needle fixing clamp and a steel needle clamped in the steel needle fixing clamp, wherein the bone fixation support comprises a tibial hole full ring arranged on the middle segment or upper segment of a tibia, a calcaneal C-type hole ring arranged on the middle segment of a calcaneus, a metatarsal proximal C-type hole ring arranged at the promxial position of a metatarsus, and a metatarsal distal C-type hole ring arranged at the distal position of the metatarsus. The talipes equines orthosis solves the technical problem that traditional talipes equines orthoses used for correcting talipes equines have difficulty in meeting the orthosis and treatment needs of talipes equines. The talipes equines orthosis has the advantages that the operation is convenient and safe, the structure is simple and ingenious, an operation is guaranteed to be finished under the microinvasive or noninvasive condition, the damage to the local soft tissue injury and blood supply is avoided to the greatest extent, the fracture healing and function reconstruction are facilitated, the curative effect is high, and the complication is low.

The invention relates to a photothermal preparation based on biliverdin, comprising biliverdin, biliverdin gel, biliverdin- Metal chelates, biliverdin-Biomolecular complex, biliverdin-Biomolecule-Metal functional assembly. The photothermal preparation has the following advantages: 1) near-infrared absorption and good tissue penetration depth, The preparation of this series of biliverdin-based photothermal preparations is of great significance for the development of multifunctional phototherapeutic drugs, and has great potential applications in tumor, dermatosis (such as pigment diseases), vascular diseases and so on. 3) Biocompatibility and metabolic mechanism are clear.

The invention provides a bias assembly and a manufacturing method, a rotating bias field generating device and a magnetotherapy instrument. The bias assembly is formed by splicing and fixing at least two permanent magnet units identical in magnetic induction intensity, the permanent magnet units are equal in length, the cross section of one of the permanent magnet unit is larger than that of the other permanent magnet unit, one end of each permanent magnet unit along the length direction is an N-electrode, and the other end is an S-electrode. The N-electrode of one of the permanent magnet unit is spliced with the S-electrode of the other permanent magnet unit through a splicing surface, and the S-electrode of one permanent magnet unit is spliced with the N-electrode of the other permanent magnet unit through a splicing surface. Magnetic fields of areas near two ends of the bias assembly are both N-electrode and S-electrode magnetic fields, one end is obvious in characteristics of the N-electrode magnetic fields, the other end is obvious in characteristics of the S-electrode magnetic fields, so bias fields are formed at areas of two ends of the bias assembly respectively, and targeted therapy on human bodies can be realized by the aid of the bias field.

The invention discloses a traditional Chinese medicinal mask and a preparation method for the same. The traditional Chinese medicinal mask is prepared from the following raw materials in parts by weight: 5 to 15 parts of stichopus japonicus selenka powder, 5 to 12 parts of indigo naturalis, 3 to 10 parts of portulacae herba, 2 to 14 parts of leonuri herba, 3 to 10 parts of arnebiae radix, 2 to 13 parts of notoginseng radix et rhizoma, 5 to 15 parts of astragali radix, 2 to 8 parts of rhodiolae crenulatae radix et rhizoma, 12 to 25 parts of salviae miltiorrhizae radix et rhizoma, 20 to 35 parts of pearl powder, 3 to 9 parts of typhonii rhizoma, 4 to 12 parts of radix paeoniae alba, 2 to 15 parts of white poria, 12 to 30 parts of angelicae dahuricae radix, 4 to 8 parts of common bletilla tuber, 1 to 4 parts of white muscardine silkworms, 12 to 30 parts of atractylodis macrocephalae rhizoma, 3 to 13 parts of ampelopsis radix, 2 to 16 parts of coptidis rhizoma, 15 to 35 parts of lonicerae japonicae flos, 3 to 12 parts of forsythiae fructus, 6 to 18 parts of aloe, 2 to 14 parts of scutellariae radix, 4 to 8 parts of moringa seeds, 3 to 14 parts of semen ginkgo, 4 to 10 parts of murraya paniculata, 10 to 20 parts of tea tree powder and 3 to 15 parts of sophorae flavescentis radix. The traditional Chinese medicinal mask is effectively used for removing and treating acnes to implement treatment of the acnes. Moreover, the traditional Chinese medicinal mask also has the effects of whitening, moisturizing, sedation and the like, and thus is suitable for groups with various types of skin to use and relatively wide in application range.

The invention relates to a traditional Chinese medicine composition used for treating gastric ulcer and a preparation method thereof. The traditional Chinese medicine composition comprises following ingredients, by weight: 10 to 20 portions of loranthus parasiticus, 10 to 20 portions of Chinese pulsatilla root, 10 to 20 portions of white peony root, 10 to 20 portions of pawpaw, 10 to 20 portions of potato, 10 to 20 portions of honey, 5 to 9 portions of radix astragali, 5 to 9 portions of radix codonopsis, 5 to 9 portions of corydalis tuber, 5 to 9 portions of radix angelicae, 5 to 9 portions of immature bitter orange, 5 to 9 portionsof trogopterus dung, 5 to 9 portions of thunberg fritillary bulb, 5 to 9 portions of fructus forsythia, 5 to 9 portions of licorice, 6 to 14 portions of platycodon grandiflorum, 6 to 14 portions of hairyvein agrimony, 6 to 14 portions of pericarpium citri reticulatae, 2 to 4 portions of pseudo-ginseng, 2 to 4 portions of rhizoma bletillae, 2 to 4 portions of cassia twig, 2 to 4 portions of ginger, and 2 to 4 portions of betel nut. Advantages of the traditional Chinese medicine composition are that: curative effect is significant, side effects are less, and the preparation method is simple.